-
1
-
-
33646855851
-
Survivin: An inhibitor of apoptosis in pediatric cancer
-
DOI 10.1002/pbc.20805
-
J.R. Fangusaro, H. Caldas, Y.Y. Jiang, and R.A. Altura Survivin: an inhibitor of apoptosis in pediatric cancer Pediatr Blood Cancer 47 2006 4 13 (Pubitemid 43787902)
-
(2006)
Pediatric Blood and Cancer
, vol.47
, Issue.1
, pp. 4-13
-
-
Fangusaro, J.R.1
Caldas, H.2
Jiang, Y.3
Altura, R.A.4
-
2
-
-
0037663452
-
Direct interaction between Survivin and Smac/DIABLO is essential for the anti-apoptotic activity of Survivin during Taxol-induced apoptosis
-
DOI 10.1074/jbc.M300957200
-
Z.Y. Song, X.B. Yao, and M. Wu Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis J Biol Chem 278 2003 23130 23140 (Pubitemid 36830379)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.25
, pp. 23130-23140
-
-
Song, Z.1
Yao, X.2
Wu, M.3
-
3
-
-
28844469941
-
Survivin: A protein with dual roles in mitosis and apoptosis
-
S.P. Wheatley, and A. McNeish Survivin: A protein with dual roles in mitosis and apoptosis Int Rev Cytol Surv Cell Biol 247 2005 35
-
(2005)
Int Rev Cytol Surv Cell Biol
, vol.247
, pp. 35
-
-
Wheatley, S.P.1
McNeish, A.2
-
4
-
-
2342635919
-
Cell death by mitotic catastrophe: A molecular definition
-
DOI 10.1038/sj.onc.1207528
-
M. Castedo, J.L. Perfettini, and T. Roumie Cell death by mitotic catastrophe: a molecular definition Oncogene 23 2004 2825 2837 (Pubitemid 38638845)
-
(2004)
Oncogene
, vol.23
, Issue.REV. ISS. 2
, pp. 2825-2837
-
-
Castedo, M.1
Perfettini, J.-L.2
Roumier, T.3
Andreau, K.4
Medema, R.5
Kroemer, G.6
-
5
-
-
3042537050
-
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy
-
DOI 10.1038/sj.onc.1207572
-
M. Castedo, J.L. Perfettini, and T. Roumier Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy Oncogene 23 2004 4362 4370 (Pubitemid 38850415)
-
(2004)
Oncogene
, vol.23
, Issue.25
, pp. 4362-4370
-
-
Castedo, M.1
Perfettini, J.-L.2
Roumier, T.3
Valent, A.4
Raslova, H.5
Yakushijin, K.6
Horne, D.7
Feunteun, J.8
Lenoir, G.9
Medema, R.10
Vainchenker, W.11
Kroemer, G.12
-
6
-
-
33750611276
-
The case for survivin as a regulator of microtubule dynamics and cell-death decisions
-
DOI 10.1016/j.ceb.2006.08.015, PII S0955067406001256
-
D.C. Altieri The case for survivin as a regulator of microtubule dynamics and cell-death decisions Curr Opin Cell Biol 18 2006 609 615 (Pubitemid 44692469)
-
(2006)
Current Opinion in Cell Biology
, vol.18
, Issue.6
, pp. 609-615
-
-
Altieri, D.C.1
-
7
-
-
0038376119
-
Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension
-
DOI 10.1093/emboj/cdg307
-
S.M.A. Lens, R.M.F. Wolthuis, and R. Klompmaker Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension EMBO J 22 2003 2934 2947 (Pubitemid 36758615)
-
(2003)
EMBO Journal
, vol.22
, Issue.12
, pp. 2934-2947
-
-
Lens, S.M.A.1
Wolthuis, R.M.F.2
Klompmaker, R.3
Kauw, J.4
Agami, R.5
Brummelkamp, T.6
Kops, G.7
Medema, R.H.8
-
8
-
-
0037366067
-
Neuroblastoma: Biological insights into a clinical enigma
-
DOI 10.1038/nrc1014
-
G.M. Brodeur Neuroblastoma: biological insights into a clinical enigma Nat Rev Cancer 3 2003 203 216 (Pubitemid 37328872)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.3
, pp. 203-216
-
-
Brodeur, G.M.1
-
9
-
-
34250683435
-
Neuroblastoma
-
DOI 10.1016/S0140-6736(07)60983-0, PII S0140673607609830
-
J.M. Maris, M.D. Hogarty, R. Bagatell, and S.L. Cohn Neuroblastoma Lancet 369 2007 2106 2120 (Pubitemid 46935947)
-
(2007)
Lancet
, vol.369
, Issue.9579
, pp. 2106-2120
-
-
Maris, J.M.1
Hogarty, M.D.2
Bagatell, R.3
Cohn, S.L.4
-
10
-
-
77953523121
-
Medical progress: Recent advances in neuroblastoma
-
J.M. Maris Medical progress: recent advances in neuroblastoma N Engl J Med 362 2010 2202 2211
-
(2010)
N Engl J Med
, vol.362
, pp. 2202-2211
-
-
Maris, J.M.1
-
11
-
-
84855957229
-
Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe
-
F. Lamers, I. van der Ploeg, and L. Schild Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe Endocr Relat Cancer 18 2011 657 668
-
(2011)
Endocr Relat Cancer
, vol.18
, pp. 657-668
-
-
Lamers, F.1
Van Der Ploeg, I.2
Schild, L.3
-
12
-
-
28544443984
-
Promoting apoptosis as a strategy for cancer drug discovery
-
DOI 10.1038/nrc1736
-
S.W. Fesik Promoting apoptosis as a strategy for cancer drug discovery Nat Rev Cancer 5 2005 876 885 (Pubitemid 41746032)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.11
, pp. 876-885
-
-
Fesik, S.W.1
-
13
-
-
22144460556
-
Apoptosis-based therapies for hematologic malignancies
-
DOI 10.1182/blood-2004-07-2761
-
J.C. Reed, and M. Pellecchia Apoptosis-based therapies for hematologic malignancies Blood 106 2005 408 418 (Pubitemid 40981231)
-
(2005)
Blood
, vol.106
, Issue.2
, pp. 408-418
-
-
Reed, J.C.1
Pellecchia, M.2
-
14
-
-
69149108005
-
Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells
-
J.J. Molenaar, M.E. Ebus, and D. Geerts Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells Proc Natl Acad Sci USA 106 2009 12968 12973
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12968-12973
-
-
Molenaar, J.J.1
Ebus, M.E.2
Geerts, D.3
-
15
-
-
70449727603
-
Antitumor activity of the selective MDM2 antagonist Nutlin-3 against chemoresistant neuroblastoma with wild-type p53
-
T. Van Maerken, L. Ferdinande, and J. Taildeman Antitumor activity of the selective MDM2 antagonist Nutlin-3 against chemoresistant neuroblastoma with wild-type p53 J Natl Cancer Inst 101 2009 1562 1574
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1562-1574
-
-
Van Maerken, T.1
Ferdinande, L.2
Taildeman, J.3
-
16
-
-
0347419432
-
Pediatric neuroblastomas: Genetic and epigenetic 'Danse Macabre'
-
DOI 10.1016/j.gene.2003.09.042
-
M.M. van Noesel, and R. Versteeg Pediatric neuroblastomas: genetic and epigenetic 'Danse Macabre' Gene 325 2004 1 15 (Pubitemid 38030371)
-
(2004)
Gene
, vol.325
, Issue.1-2
, pp. 1-15
-
-
Van Noesel, M.M.1
Versteeg, R.2
-
17
-
-
77950863805
-
BH3 response profiles from neuroblastoma mitochondria predict activity of small molecule Bcl-2 family antagonists
-
K.C. Goldsmith, B.J. Lestini, and M. Gross BH3 response profiles from neuroblastoma mitochondria predict activity of small molecule Bcl-2 family antagonists Cell Death Differ 17 2010 872 882
-
(2010)
Cell Death Differ
, vol.17
, pp. 872-882
-
-
Goldsmith, K.C.1
Lestini, B.J.2
Gross, M.3
-
18
-
-
85046914188
-
Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists
-
B.J. Lestini, K.C. Goldsmith, and M.N. Fluchel Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists Cancer Biol Ther 8 2009 1587 1595
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1587-1595
-
-
Lestini, B.J.1
Goldsmith, K.C.2
Fluchel, M.N.3
-
19
-
-
77949563626
-
Down-modulation of survivin expression and inhibition of tumor growth in vivo by EZN-3042, a locked nucleic acid antisense oligonucleotide
-
P. Sapra, M. Wang, R. Bandaru, H. Zhao, L.M. Greenberger, and I.D. Horak Down-modulation of survivin expression and inhibition of tumor growth in vivo by EZN-3042, a locked nucleic acid antisense oligonucleotide Nucleosides Nucleotides Nucleic Acids 29 2010 97 112
-
(2010)
Nucleosides Nucleotides Nucleic Acids
, vol.29
, pp. 97-112
-
-
Sapra, P.1
Wang, M.2
Bandaru, R.3
Zhao, H.4
Greenberger, L.M.5
Horak, I.D.6
-
20
-
-
70350234507
-
Survivin: A new target for anti-cancer therapy
-
B.M. Ryan, N. O'Donovan, and M.J. Duffy Survivin: a new target for anti-cancer therapy Cancer Treat Rev 35 2009 553 562
-
(2009)
Cancer Treat Rev
, vol.35
, pp. 553-562
-
-
Ryan, B.M.1
O'Donovan, N.2
Duffy, M.J.3
-
21
-
-
34548574823
-
YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts
-
DOI 10.1158/0008-5472.CAN-07-1343
-
T. Nakahara, M. Takeuchi, and I. Kinoyama YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts Cancer Res 67 2007 8014 8021 (Pubitemid 47395135)
-
(2007)
Cancer Research
, vol.67
, Issue.17
, pp. 8014-8021
-
-
Nakahara, T.1
Takeuchi, M.2
Kinoyama, I.3
Minematsu, T.4
Shirasuna, K.5
Matsuhisa, A.6
Kita, A.7
Tominaga, F.8
Yamanaka, K.9
Kudoh, M.10
Sasamata, M.11
-
22
-
-
66649126940
-
Phase i study of YM155, a novel survivin suppressant, in patients with advanced solid tumors
-
T. Satoh, I. Okamoto, and M. Miyazaki Phase I study of YM155, a novel survivin suppressant, in patients with advanced solid tumors Clin Cancer Res 15 2009 3872 3880
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3872-3880
-
-
Satoh, T.1
Okamoto, I.2
Miyazaki, M.3
-
23
-
-
55949118445
-
Phase i and pharmacokinetic study of YM155, a small-molecule inhibitor of survivin
-
A.W. Tolcher, A. Mita, and L.D. Lewis Phase I and pharmacokinetic study of YM155, a small-molecule inhibitor of survivin J Clin Oncol 26 2008 5198 5203
-
(2008)
J Clin Oncol
, vol.26
, pp. 5198-5203
-
-
Tolcher, A.W.1
Mita, A.2
Lewis, L.D.3
-
24
-
-
79151481416
-
A multi-center phase II evaluation of the small molecule survivin suppressor YM155 in patients with unresectable stage III or IV melanoma
-
K.D. Lewis, W. Samlowski, and J. Ward A multi-center phase II evaluation of the small molecule survivin suppressor YM155 in patients with unresectable stage III or IV melanoma Invest New Drugs 29 2011 161 166
-
(2011)
Invest New Drugs
, vol.29
, pp. 161-166
-
-
Lewis, K.D.1
Samlowski, W.2
Ward, J.3
-
25
-
-
76749118103
-
Multicenter phase II trial of YM155, a small-molecule suppressor of survivin, in patients with advanced, refractory, non-small-cell lung cancer
-
G. Giaccone, P. Zatloukal, and J. Roubec Multicenter phase II trial of YM155, a small-molecule suppressor of survivin, in patients with advanced, refractory, non-small-cell lung cancer J Clin Oncol 27 2009 4481 4486
-
(2009)
J Clin Oncol
, vol.27
, pp. 4481-4486
-
-
Giaccone, G.1
Zatloukal, P.2
Roubec, J.3
-
26
-
-
0033922511
-
Inhibitory effect of the reversal agents V-104, GF120918 and pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport
-
R. Evers, M. Kool, and A.J. Smith Inhibitory effect of the reversal agents V-104, GF120918 and pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport Br J Cancer 83 2000 366 374 (Pubitemid 30453578)
-
(2000)
British Journal of Cancer
, vol.83
, Issue.3
, pp. 366-374
-
-
Evers, R.1
Kool, M.2
Smith, A.J.3
Van Deemter, L.4
De Haas, M.5
Borst, P.6
-
27
-
-
37349069575
-
Quantitation of doxorubicin uptake, efflux, and modulation of multidrug resistance (MDR) in MDR human cancer cells
-
DOI 10.1124/jpet.107.127704
-
F. Shen, S. Chu, and A.K. Bence Quantitation of doxorubicin uptake, efflux, and modulation of multidrug resistance (MDR) in MDR human cancer cells J Pharmacol Exp Ther 324 2008 95 102 (Pubitemid 350294163)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.324
, Issue.1
, pp. 95-102
-
-
Shen, F.1
Chu, S.2
Bence, A.K.3
Bailey, B.4
Xue, X.5
Erickson, P.A.6
Montrose, M.H.7
Beck, W.T.8
Erickson, L.C.9
-
28
-
-
0032486795
-
Availability of PSC833, a substrate and inhibitor of poglycoproteins, in various concentrations of serum
-
A.J. Smith, U. Mayer, A.H. Schinkel, and P. Borst Availability of PSC833, a substrate and inhibitor of P-glycoproteins, in various concentrations of serum J Natl Cancer Inst 90 1998 1161 1166 (Pubitemid 28380721)
-
(1998)
Journal of the National Cancer Institute
, vol.90
, Issue.15
, pp. 1161-1166
-
-
Smith, A.J.1
Mayer, U.2
Schinkel, A.H.3
Borst, P.4
-
29
-
-
42349108110
-
Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma
-
DOI 10.1158/0008-5472.CAN-07-5032
-
J.J. Molenaar, M.E. Ebus, and J. Koster Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma Cancer Res 68 2008 2599 2609 (Pubitemid 351556258)
-
(2008)
Cancer Research
, vol.68
, Issue.8
, pp. 2599-2609
-
-
Molenaar, J.J.1
Ebus, M.E.2
Koster, J.3
Van Sluis, P.4
Van Noesel, C.J.M.5
Versteeg, R.6
Caron, H.N.7
-
30
-
-
77956705398
-
System-level analysis of neuroblastoma tumor-initiating cells implicates AURKB as a novel drug target for neuroblastoma
-
O. Morozova, M. Vojvodic, and N. Grinshtein System-level analysis of neuroblastoma tumor-initiating cells implicates AURKB as a novel drug target for neuroblastoma Clin Cancer Res 16 2010 4572 4582
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4572-4582
-
-
Morozova, O.1
Vojvodic, M.2
Grinshtein, N.3
-
31
-
-
2542491777
-
The role of ABC transporters in drug resistance, metabolism and toxicity
-
H. Glavinas, P. Krajcsi, J. Cserepes, and B. Sarkadi The role of ABC transporters in drug resistance, metabolism and toxicity Curr Drug Deliv 1 2004 27 42
-
(2004)
Curr Drug Deliv
, vol.1
, pp. 27-42
-
-
Glavinas, H.1
Krajcsi, P.2
Cserepes, J.3
Sarkadi, B.4
-
32
-
-
34248591193
-
Drugs, their targets and the nature and number of drug targets (vol 5, pg 821, 2006)
-
P. Imming, C. Sinning, and A. Meyer Drugs, their targets and the nature and number of drug targets (vol 5, pg 821, 2006) Nat Rev Drug Discov 6 2007 126
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 126
-
-
Imming, P.1
Sinning, C.2
Meyer, A.3
-
33
-
-
65949125105
-
In vivo antitumor and antimetastatic activity of sunitinib in preclinical neuroblastoma mouse model
-
L. Zhang, K.M. Smith, and A.L. Chong In vivo antitumor and antimetastatic activity of sunitinib in preclinical neuroblastoma mouse model Neoplasia 11 2009 426 435
-
(2009)
Neoplasia
, vol.11
, pp. 426-435
-
-
Zhang, L.1
Smith, K.M.2
Chong, A.L.3
-
34
-
-
33745746815
-
Pharmacological strategies for overcoming multidrug resistance
-
S. Nobili, I. Landini, B. Giglioni, and E. Mini Pharmacological strategies for overcoming multidrug resistance Curr Drug Targets 7 2006 861 879
-
(2006)
Curr Drug Targets
, vol.7
, pp. 861-879
-
-
Nobili, S.1
Landini, I.2
Giglioni, B.3
Mini, E.4
|