-
1
-
-
0023884310
-
Bioactivation of the narcotic drug codeine in human-liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome-P-450 Dbl/Bufi)
-
Dayer P, Desmeules J, Leemann T, et al. Bioactivation of the narcotic drug codeine in human-liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome-P-450 Dbl/Bufi). Biochem Biophys Res Commun. 1988;152:411-416.
-
(1988)
Biochem Biophys Res Commun
, vol.152
, pp. 411-416
-
-
Dayer, P.1
Desmeules, J.2
Leemann, T.3
-
2
-
-
0023795013
-
Polymorphic O-demethylation of codeine
-
Chen ZR, Somogyi AA, Bochner F. Polymorphic O-demethylation of codeine. Lancet. 1988;2:914-915.
-
(1988)
Lancet
, vol.2
, pp. 914-915
-
-
Chen, Z.R.1
Somogyi, A.A.2
Bochner, F.3
-
3
-
-
38349132802
-
The CYP2D6 activity score: Translating genotype information into a qualitative measure of phenotype
-
Gaedigk A, Simon SD, Pearce RE, et al. The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype. Clin Pharmacol Ther. 2008;83:234-242.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 234-242
-
-
Gaedigk, A.1
Simon, S.D.2
Pearce, R.E.3
-
4
-
-
80051793585
-
CYP2D6 polymorphisms and codeine analgesia in postpartum pain management: A pilot study
-
vanderVaart S, Berger H, Sistonen J, et al. CYP2D6 polymorphisms and codeine analgesia in postpartum pain management: a pilot study. Ther Drug Monitor. 2011;33:425-432.
-
(2011)
Ther Drug Monitor.
, vol.33
, pp. 425-432
-
-
Vandervaart, S.1
Berger, H.2
Sistonen, J.3
-
5
-
-
33846643134
-
Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: Characterization of gene duplication events
-
DOI 10.1038/sj.clpt.6100033, PII 6100033
-
Gaedigk A, Ndjountche L, Divakaran K, et al. Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events. Clin Pharmacol Ther. 2007;81:242-251. (Pubitemid 46178274)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.81
, Issue.2
, pp. 242-251
-
-
Gaedigk, A.1
Ndjountche, L.2
Divakaran, K.3
Dianne Bradford, L.4
Zineh, I.5
Oberlander, T.F.6
Brousseau, D.C.7
McCarver, D.G.8
Johnson, J.A.9
Alander, S.W.10
Riggs, K.W.11
Leeder, J.S.12
-
6
-
-
33747134323
-
Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother
-
DOI 10.1016/S0140-6736(06)69255-6, PII S0140673606692556
-
Koren G, Cairns J, Chitayak D, et al. Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother. Lancet. 2006;368:704. (Pubitemid 44223697)
-
(2006)
Lancet
, vol.368
, Issue.9536
, pp. 704
-
-
Koren, G.1
Cairns, J.2
Chitayat, D.3
Gaedigk, A.4
Leeder, S.J.5
-
7
-
-
57749180179
-
Pharmacogenetics of neonatal opioid toxicity following maternal use of codeine during breastfeeding: A case-control study
-
Madadi P, Ross CJD, Hayden MR, et al. Pharmacogenetics of neonatal opioid toxicity following maternal use of codeine during breastfeeding: a case-control study. Clin Pharmacol Ther. 2009;85:31-35.
-
(2009)
Clin Pharmacol Ther
, vol.85
, pp. 31-35
-
-
Madadi, P.1
Cjd, R.2
Hayden, M.R.3
-
8
-
-
69049096090
-
Codeine, ultrarapidmetabolism genotype, and postoperative death
-
Ciszkowski C, Madadi P, Phillips MS, et al. Codeine, ultrarapidmetabolism genotype, and postoperative death. N Engl J Med. 2009;361: 827-828.
-
(2009)
N Engl J Med
, vol.361
, pp. 827-828
-
-
Ciszkowski, C.1
Madadi, P.2
Phillips, M.S.3
-
9
-
-
0025114258
-
Identification of the primary gene defect at the cytochrome-P450 Cyp2d locus
-
Gough AC, Miles JS, Spurr NK, et al. Identification of the primary gene defect at the cytochrome-P450 Cyp2d locus. Nature. 1990;347: 773-776.
-
(1990)
Nature
, vol.347
, pp. 773-776
-
-
Gough, A.C.1
Miles, J.S.2
Spurr, N.K.3
-
10
-
-
0029102348
-
Detection of the poor metabolizer-associated Cyp2d6(D) gene deletion allele by long-Pcr technology
-
Steen VM, Andreassen OA, Daly AK, et al. Detection of the poor metabolizer-associated Cyp2d6(D) gene deletion allele by long-Pcr technology. Pharmacogenetics. 1995;5:215-223.
-
(1995)
Pharmacogenetics
, vol.5
, pp. 215-223
-
-
Steen, V.M.1
Andreassen, O.A.2
Daly, A.K.3
-
11
-
-
37549037483
-
Enhanced buprenorphine analgesia with the addition of ultra-low-dose naloxone in healthy subjects
-
La Vincente SF, White JM, Somogyi AA, et al. Enhanced buprenorphine analgesia with the addition of ultra-low-dose naloxone in healthy subjects. Clin Pharmacol Ther. 2008;83:144-152.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 144-152
-
-
La Vincente, S.F.1
White, J.M.2
Somogyi, A.A.3
-
12
-
-
0033899996
-
Action of naloxone on gender-dependent analgesic and antianalgesic effects of nalbuphine in humans
-
Gear RW, Miaskowski C, Gordon NC, et al. Action of naloxone on gender-dependent analgesic and antianalgesic effects of nalbuphine in humans. J Pain. 2000;1:122-127. (Pubitemid 30640010)
-
(2000)
Journal of Pain
, vol.1
, Issue.2
, pp. 122-127
-
-
Gear, R.W.1
Miaskowski, C.2
Gordon, N.C.3
Paul, S.M.4
Heller, P.H.5
Levine, J.D.6
-
13
-
-
0038054454
-
Ultra-low dose oral naltrexone decreases side effects and potentiates the effect of methadone [1]
-
DOI 10.1016/S0885-3924(03)00139-8
-
Cruciani RA, Lussier D, Miller-Saultz D, et al. Ultra-low dose oral naltrexone decreases side effects and potentiates the effect of methadone. J Pain Symptom Manage. 2003;25:491-494. (Pubitemid 36629270)
-
(2003)
Journal of Pain and Symptom Management
, vol.25
, Issue.6
, pp. 491-494
-
-
Cruciani, R.A.1
Lussier, D.2
Miller-Saultz, D.3
Arbuck, D.M.4
-
14
-
-
0038662902
-
Response of neuropathic trigeminal pain to the combination of low-dose nalbuphine plus naloxone in humans
-
DOI 10.1016/S0304-3940(03)00356-2
-
Schmidt BL, Gear RW, Levine JD. Response of neuropathic trigeminal pain to the combination of low-dose nalbuphine plus naloxone in humans. Neurosci Lett. 2003;343:144-146. (Pubitemid 36577535)
-
(2003)
Neuroscience Letters
, vol.343
, Issue.2
, pp. 144-146
-
-
Schmidt, B.L.1
Gear, R.W.2
Levine, J.D.3
-
15
-
-
0347355442
-
Addition of ultralow dose naloxone to postoperative morphine PCA: Unchanged analgesia and opioid requirement but decreased incidence of opioid side effects
-
DOI 10.1016/j.pain.2003.09.011
-
Cepeda MS, Alvarez H, Morales O, et al. Addition of ultralow dose naloxone to postoperative morphine PCA: unchanged analgesia and opioid requirement but decreased incidence of opioid side effects. Pain. 2004;107:41-46. (Pubitemid 38058697)
-
(2004)
Pain
, vol.107
, Issue.1-2
, pp. 41-46
-
-
Cepeda, M.S.1
Alvarez, H.2
Morales, O.3
Carr, D.B.4
-
16
-
-
84858705453
-
Angelman syndrome.
-
Pagon RA Bird TD Dolan CR et al eds Seattle WA: University of Washington Accessed October 1, 2011
-
Dagli AI, Williams CA. Angelman syndrome. In: Pagon RA, Bird TD, Dolan CR, et al, eds. GeneReviews. Seattle, WA: University of Washington; 1993-2011. Available at http://genetests.org. Accessed October 1, 2011.
-
(1993)
GeneReviews
-
-
Dagli, A.I.1
Williams, C.A.2
-
17
-
-
77955578706
-
Mutations affecting GABAergic signaling in seizures and epilepsy
-
Galanopoulou AS. Mutations affecting GABAergic signaling in seizures and epilepsy. Pflugers Arch. 2010;460:505-523.
-
(2010)
Pflugers Arch.
, vol.460
, pp. 505-523
-
-
Galanopoulou, A.S.1
-
18
-
-
40049099239
-
Epilepsy in Angelman syndrome
-
DOI 10.1016/j.seizure.2007.08.004, PII S1059131107001872
-
Pelc K, Boyd SG, Cheron G, et al. Epilepsy in Angelman syndrome. Seizure. 2008;17:211-217. (Pubitemid 351324161)
-
(2008)
Seizure
, vol.17
, Issue.3
, pp. 211-217
-
-
Pelc, K.1
Boyd, S.G.2
Cheron, G.3
Dan, B.4
-
19
-
-
43449093723
-
Are there distinctive sleep problems in Angelman syndrome?
-
DOI 10.1016/j.sleep.2007.07.001, PII S1389945707002547
-
Pelc K, Cheron G, Boyd SG, et al. Are there distinctive sleep problems in Angelman syndrome? Sleep Med. 2008;9:434-441. (Pubitemid 351664084)
-
(2008)
Sleep Medicine
, vol.9
, Issue.4
, pp. 434-441
-
-
Pelc, K.1
Cheron, G.2
Boyd, S.G.3
Dan, B.4
-
22
-
-
0017913133
-
Naloxone as a GABA antagonist: evidence from iontophoretic, receptor binding and convulsant studies
-
Dingledine R, Iversen LL, Breuker E. Naloxone as a Gaba antagonist-evidence from Iontophoretic, receptor-binding and convulsant studies. Eur J Pharmacol. 1978;47:19-27. (Pubitemid 8244114)
-
(1978)
European Journal of Pharmacology
, vol.47
, Issue.1
, pp. 19-27
-
-
Dingledine, R.1
Iversen, L.L.2
Breuker, E.3
-
23
-
-
62549125960
-
The hypoalgesic effect of oxycodone in human experimental pain models in relation to the CYP2D6 oxidation polymorphism
-
Zwisler ST, Enggaard TP, Noehr-Jensen L, et al. The hypoalgesic effect of oxycodone in human experimental pain models in relation to the CYP2D6 oxidation polymorphism. Basic Clin Pharmacol Toxicol. 2009; 104:335-344.
-
(2009)
Basic Clin Pharmacol Toxicol
, vol.104
, pp. 335-344
-
-
Zwisler, S.T.1
Enggaard, T.P.2
Noehr-Jensen, L.3
-
24
-
-
80053914289
-
The metabolism of opioid agents and the clinical impact of their active metabolites
-
Smith HS. The metabolism of opioid agents and the clinical impact of their active metabolites. Clin J Pain. 2011;27:824-838.
-
(2011)
Clin J Pain.
, vol.27
, pp. 824-838
-
-
Smith, H.S.1
-
25
-
-
67650736252
-
Opioid metabolism
-
Smith HS. Opioid metabolism. Mayo Clinic Proc. 2009;84:613-624.
-
(2009)
Mayo Clinic Proc.
, vol.84
, pp. 613-624
-
-
Smith, H.S.1
|