High-dose Spatially Fractionated GRID Radiation Therapy (SFGRT): A comparison of treatment outcomes with Cerrobend vs. MLC SFGRT

International Journal of Radiation Oncology Biology Physics

Volumn 82, Issue 5, 2012, Pages 1642-1649

  Neuner, Geoffrey ^a   Mohiuddin, Majid M ^b   Vander Walde, Noam ^c   Goloubeva, Olga ^d   Ha, Jonathan ^e   Yu, Cedric X ^a   Regine, William F ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cerrobend; GRID; Multileaf collimator (MLC); Palliation; Spatially fractionated radiation (SFGRT)

Indexed keywords

CERROBEND; FRACTIONATED RADIATION; GRID; MULTILEAF COLLIMATORS; PALLIATION;

HEALTH; RADIOTHERAPY; TOXICITY; TUMORS;

SURVEYS;

ANUS CANCER; ARTICLE; BLEEDING; BREAST CANCER; CANCER RADIOTHERAPY; COLON CANCER; CONTROLLED STUDY; CORREBEND BLOCK SPATIALLY FRACTIONATED GRID RADIATION THERAPY; DYSPHAGIA; DYSPNEA; ESOPHAGUS CANCER; EXTERNAL BEAM RADIOTHERAPY; FEMALE; HEAD AND NECK CANCER; HUMAN; INTERMETHOD COMPARISON; LIVER CANCER; LUNG CANCER; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MULTILEAF COLLIMATOR SPATIALLY FRACTIONATED GRID RADIATION THERAPY; ODOR; OVARY CANCER; PAIN; PALLIATIVE THERAPY; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE; RANGE OF MOTION; RETROSPECTIVE STUDY; SARCOMA; SKIN CANCER; SPATIALLY FRACTIONATED GRID RADIATION THERAPY; THYROID CANCER; TREATMENT OUTCOME; TREATMENT RESPONSE; TUMOR VOLUME;

DOSE FRACTIONATION; EQUIPMENT DESIGN; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; LUNG NEOPLASMS; MALE; NEOPLASMS; PAIN; PALLIATIVE CARE; PARTICLE ACCELERATORS; RADIATION EQUIPMENT AND SUPPLIES; RADIATION INJURIES; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; TUMOR BURDEN;

EID: 84858706256     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.01.065     Document Type: Article

References (15)

1. Johnson CR, Thames HD, Huang DT, Schmidt-Ullrich RK. The tumor volume and clonogen number relationship: Tumor control predictions based upon tumor volume estimates derived from computed tomography. Int J Radiat Oncol Biol Phys 1995;33:281-287.
2. Mohiuddin M, Curtis DL, GrizosWT, Komarnicky L. Palliative treatment of advanced cancer using multiple nonconfluent pencil beam radiation. A pilot study. Cancer 1990;66:114-118. (Pubitemid 20197094)
3. Marks H. Clinical experience with irradiation through a grid. Radiology 1952;58:338-342.
4. Mohiuddin M, Fujita M, Regine WF, Megooni AS, Ibbott GS, Ahmed MM. High-dose spatially-fractionated radiation (GRID): A new paradigm in the management of advanced cancers. Int J Radiat Oncol Biol Phys 1999;45:721-727. (Pubitemid 29462655)
5. Huhn JL, Regine WF, Valentino JP, Meigooni AS, Kudrimoti M, Mohiuddin M. Spatially fractionated GRID radiation treatment of advanced neck disease associated with head and neck cancer. Technol Cancer Res Treat 2006;5:607-612. (Pubitemid 46075034)
6. Penagaricano JA, Moros EG, Ratanatharathorn V, Yan Y, Corry P. Evaluation of spatially fractionated radiotherapy (GRID) and definitive chemoradiotherapy with curative intent for locally advanced squamous cell carcinoma of the head and neck: Initial response rates and toxicity. Int J Radiat Oncol Biol Phys 2010 Apr;76(5):1369-1375.
7. Ha JK, Zhang G, Naqvi SA, Regine WF, Yu CX. Feasibility of delivering grid therapy using a multileaf collimator. Med Phys 2006;33:76-82. (Pubitemid 43121035)
8. Zhang H, Wang JZ, Mayr N, et al. Fractionated grid therapy in treating cervical cancers: Conventional fractionation or hypofractionation? Int J Radiat Oncol Biol Phys 2008;70:280-288. (Pubitemid 350251047)
9. Mohiuddin M, Kudrimoti M, Regine W, Meigooni A, Ahmed M, Zwicker R. Spatially fractionated radiation (SFR) in the management of advanced cancers. Int J Radiat Oncol Biol Phys 2002;54:342-343.
10. Somaiah N,Warrington J, Taylor H, Ahmad R, Tait D, Glees J. High dose spatially fractionated radiotherapy (SFR) using a megavoltage GRID in advanced lung tumors: Preliminary experience in UK. Int J Radiat Oncol Biol Phys 2008;72:S490.
11. Kudrimoti M, Mohiuddin M, Ahmed M, Meigooni A, Hanna N, Regine W, Huhn J. Use of high dose spatially fractionated radiation (GRID therapy) in management of large, poor prognostic stage III (> 10cms) soft tissue sarcomas. Int J Radiat Biol Oncol Phys 2004;60:S575.
12. Sathishkumar S, Boyanovsky B, Karakashian AA, et al. Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: Implications for endothelial apoptosis. Cancer Biol Ther 2005;4:979-986. (Pubitemid 41598594)
13. Sathishkumar S, Dey S, Meigooni AS, et al. The impact of TNF-alpha induction on therapeutic efficacy following high dose spatially fractionated (GRID) radiation. Technol Cancer Res Treat 2002;1:141-147. (Pubitemid 36554427)
14. Fuks Z, Kolesnick R. Engaging the vascular component of the tumor response. Cancer Cell 2005;8:89-91. (Pubitemid 41132735)
15. Crosbie JC, Anderson RL, Rothkamm K, et al. Tumor cell response to synchrotron microbeam radiation therapy differs markedly from cells in normal tissues. Int J Radiat Oncol Biol Phys 2010;77:886-894.