Plasma profiling by a protein array approach identifies IGFBP-1 as a novel biomarker of abdominal aortic aneurysm

Atherosclerosis

Volumn 221, Issue 2, 2012, Pages 544-550

  Ramos Mozo, P ^a   Rodriguez, C ^c   Pastor Vargas, C ^b   Blanco Colio, L M ^a   Martinez Gonzalez, J ^c   Meilhac, O ^e   Michel, J B ^e   De Ceniga, M Vega ^d   Egido, J ^a   Martin Ventura, J L ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b HOSPITAL UNIVERSITARIO FUNDACIÓN JIMÉNEZ DÍAZ   (Spain)

^c Institut Català de Ciències Cardiovasculars   (Spain)

^d HOSPITAL DE GALDAKAO   (Spain)

^e INSERM   (France)

Author keywords

Abdominal aortic aneurysm; Biomarkers; Platelets; Thrombosis

Indexed keywords

EOTAXIN 2; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN C;

ABDOMINAL AORTA ANEURYSM; AGED; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MICROARRAY; THROMBOCYTE AGGREGATION; THROMBUS; WESTERN BLOTTING;

AGED; AORTIC ANEURYSM, ABDOMINAL; AORTOGRAPHY; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CULTURE MEDIA, CONDITIONED; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR I; LINEAR MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PLATELET AGGREGATION; PREDICTIVE VALUE OF TESTS; PROTEIN ARRAY ANALYSIS; PROTEOMICS; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; RISK FACTORS; SPAIN; TISSUE CULTURE TECHNIQUES; TOMOGRAPHY, X-RAY COMPUTED; UP-REGULATION;

EID: 84858705916     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.01.009     Document Type: Article

References (30)

1. Sakalihasan N., Limet R., Defawe O.D. Abdominal aortic aneurysm. Lancet 2005, 365:1577-1589.
2. Michel J.B., Martin-Ventura J.L., Egido J., et al. Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans. Cardiovasc Res 2011, 90:18-27.
3. Baxter B.T., Terrin M.C., Dalman R.L. Medical management of small abdominal aortic aneurysms. Circulation 2008, 117:1883-1889.
4. Urbonavicius S., Urbonaviciene G., Honore B., Henneberg E.W., Vorum H., Lindholt J.S. Potential circulating biomarkers for abdominal aortic aneurysm expansion and rupture-a systematic review. Eur J Vasc Endovasc Surg 2008, 36:273-280.
5. Golledge J., Tsao P.S., Dalman R.L., Norman P.E. Circulating markers of abdominal aortic aneurysm presence and progression. Circulation 2008, 118:2382-2392.
6. Blanco-Colio L.M., Lopez J.A., Martinez-Pinna R., Egido J., Martin-Ventura J.L. Vascular proteomics, a translational approach: from traditional to novel proteomic techniques. Expert Rev Proteomics 2009, 6:461-464.
7. Nordon I., Brar R., Hinchliffe R., Cockerill G., Loftus I., Thompson M. The role of proteomic research in vascular disease. J Vasc Surg 2009, 49:1602-1612.
8. Granger J., Siddiqui J., Copeland S., Remick D. Albumin depletion of human plasma also removes low abundance proteins including the cytokines. Proteomics 2005, 5:4713-4718.
9. Schwenk J.M., Igel U., Kato B.S., et al. Comparative protein profiling of serum and plasma using an antibody suspension bead array approach. Proteomics 2010, 10:532-540.
10. Martinez-Pinna R., Barbas C., Blanco-Colio L.M., et al. Proteomic and metabolomic profiles in atherothrombotic vascular disease. Curr Atheroscler Rep 2010, 12:202-208.
11. Golledge A.L., Walker P., Norman P.E., Golledge J. A systematic review of studies examining inflammation associated cytokines in human abdominal aortic aneurysm samples. Dis Markers 2009, 26:181-188.
12. Golledge J., Clancy P., Moran C., et al. The novel association of the chemokine CCL22 with abdominal aortic aneurysm. Am J Pathol 2010, 176:2098-2106.
13. Caligiuri G., Rossignol P., Julia P., et al. Reduced immunoregulatory CD31+ T cells in patients with atherosclerotic abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 2006, 26:618-623.
14. Badimon L., Martínez-González J., Royo T., Lassila R., Badimon J.J. A sudden increase in plasma epinephrine levels transiently enhances platelet deposition on severely damaged arterial wall. Thromb Haemost 1999, 82:1736-1742.
15. Motani A.S., Anggård E.E., Ferns G.A. Recombinant insulin-like growth factor-1 modulates aggregation in human platelets via extracellular calcium. Life Sci 1996, 58:PL269-PL274.
16. Kodali R., Hajjou M., Berman A.B., et al. Chemokines induce matrix metalloproteinase-2 through activation of epidermal growth factor receptor in arterial smooth muscle cells. Cardiovasc Res 2006, 69:706-715.
17. van Kuijk J.P., Flu W.J., Chonchol M., Bax J.J., Verhagen H.J., Poldermans D. Metabolic syndrome is an independent predictor of cardiovascular events in high-risk patients with occlusive and aneurysmatic peripheral arterial disease. Atherosclerosis 2010, 210:596-601.
18. Lang C.H., Nystrom G.J., Frost R.A. Tissue-specific regulation of IGF-I and IGF-binding proteins in response to TNFalpha. Growth Horm IGF Res 2001, 11:250-260.
19. Norman P., Le M., Pearce C., Jamrozik K. Infrarenal aortic diameter predicts all-cause mortality. Arterioscler Thromb Vasc Biol 2004, 24:1278-1282.
20. Houard X., Rouzet F., Touat Z., et al. Topology of the fibrinolytic system within the mural thrombus of human abdominal aortic aneurysms. J Pathol 2007, 212:20-28.
21. Houard X., Touat Z., Ollivier V., et al. Mediators of neutrophil recruitment in human abdominal aortic aneurysms. Cardiovasc Res 2009, 82:532-541.
22. Panek B., Gacko M., Pałka J. Metalloproteinases, insulin-like growth factor-I and its binding proteins in aortic aneurysm. Int J Exp Pathol 2004, 85:159-164.
23. Gibson T.L., Cohen P. Inflammation-related neutrophil proteases, cathepsin G and elastase, function as insulin-like growth factor binding protein proteases. Growth Horm IGF Res 1999, 9:241-253.
24. Mañes S., Mira E., Barbacid M.M., et al. Identification of insulin-like growth factor-binding protein-1 as a potential physiological substrate for human stromelysin-3. J Biol Chem 1997, 272:25706-25712.
25. Wheatcroft S.B., Kearney M.T. IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis. Trends Endocrinol Metab 2009, 20:153-162.
26. Motani A., Rutherford C., Anggard E.E., Ferns G.A. Insulin-like growth factor binding protein-1 inhibits arterial smooth muscle cell proliferation in vitro but does not reduce the neointimal response to balloon catheter injury. Atherosclerosis 1995, 118:57-66.
27. Gustafsson T., Andersson P., Arnqvist H.J. Different inhibitory actions of IGFBP-1, -2 and -4 on IGF-I effects in vascular smooth muscle cells. J Endocrinol 1999, 161:245-253.
28. Karey K.P., Sirbasku D.A. Human platelet-derived mitogens, II: subcellular localization of insulin like growth factor I to the alpha-granule and release in response to thrombin. Blood 1989, 74:1093-1100.
29. Myronovych A., Murata S., Chiba M., et al. Role of platelets on liver regeneration after 90% hepatectomy in mice. J Hepatol 2008, 49:363-372.
30. Marcinkiewicz M., Gordon P.V. A role for plasmin in platelet aggregation: differential regulation of IGF release from IGF-IGFBP complexes?. Growth Horm IGF Res 2008, 18:325-334.