Hollow spheroids in ascites of ovarian clear cell carcinoma: How are they formed and how do they behave?

Cytopathology

Volumn 23, Issue 2, 2012, Pages 120-125

  Kato, N ^a   Narutomi, K ^b   Fukase, M ^b   Motoyama, T ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b Tsuruoka Municipal Shonai Hospital   (Japan)

Author keywords

Ascites; Clear cell carcinoma; Heterotransplantation; Hyaluronan; Ovary; Scaffold; Spheroid

Indexed keywords

HYALURONIC ACID;

ABDOMINAL TUMOR; ANIMAL CELL; ARTICLE; ASCITES FLUID CYTOLOGY; ASCITES TUMOR CELL; CANCER CELL CULTURE; CARCINOMA CELL; CLEAR CELL CARCINOMA; CONTROLLED STUDY; FEMALE; HISTOLOGY; IN VITRO STUDY; MOUSE; NONHUMAN; OVARY CARCINOMA; PERITONEAL CAVITY; PRIORITY JOURNAL; TUMOR SPHEROID; XENOTRANSPLANTATION;

ADENOCARCINOMA, CLEAR CELL; ANIMALS; ASCITES; BIOLOGICAL SPECIMEN BANKS; CYTOLOGICAL TECHNIQUES; FEMALE; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; OVARIAN NEOPLASMS; SPHEROIDS, CELLULAR; SUSPENSIONS; TUMOR CELLS, CULTURED;

EID: 84858699255     PISSN: 09565507     EISSN: 13652303     Source Type: Journal    
DOI: 10.1111/j.1365-2303.2011.00847.x     Document Type: Article

References (15)

1. Nishida M, Kuramoto H, Tatsumi H, Miura T, Arai M. Cytological findings of ascites in patients with ovarian clear cell carcinoma. Diagnostic significance and genesis of mirror ball pattern. Nippon Rinsho Saibo Gakkai Zasshi 1979;18:280-94. (in Japanese with English Abstr)
2. Allen HJ, Porter C, Gamarra M, Piver MS, Johnson EAZ. Isolation and morphologic characterization of human ovarian carcinoma cell clusters present in effusions. Expl Cell Biol 1987;55:194-208.
3. Kato N, Takeda J, Fukase M, Motoyama T. Alternate mucoid and hyalinized stroma in clear cell carcinoma of the ovary: a manifestation of serial stromal remodeling. Mod Pathol 2010;23:881-8.
4. Kobayashi H, Man S, Graham CH et al. Acquired multicellular-mediated resistance to alkylating agents in cancer. Proc Natl Acad Sci USA 1993;90:3294-8.
5. Makhija S, Taylor DD, Gibb RK, Gercel-Taylor C. Taxol-induced bcl-2 phosphorylation in ovarian cancer cell monolayer and spheroids. Int J Oncol 1999;14:515-21.
6. L'Esperance S, Bachvarova M, Tetu B, Mes-Masson AM, Bachvarov D. Global gene expression analysis of early response to chemotherapy treatment in ovarian cancer spheroids. BMC Genomics 2008;9:99.
7. Shield K, Ackland ML, Ahmed N, Rice GE. Multicellular spheroids in ovarian cancer metastases: biology and pathology. Gynecol Oncol 2009;113:143-8.
8. Goff BA, Sainz de la Cuesta R, Muntz HG et al. Clear cell carcinoma of the ovary: A distinct histologia type with poor prognosis and resistance to platinum-based chemotherapy in stage III disease. Gynecol Oncol 1996;60:412-7.
9. Tammela J, Geisler JP, Eskew PN, Geisler HE. Clear cell carcinoma of the ovary: poor prognosis compared to serous carcinoma. Eur J Gynecol Oncol 1998;19:438-40.
10. Sugiyama T, Kamura T, Kigawa J et al. Clinical characteristics of clear cell carcinoma of the ovary: a distinct histological type with poor prognosis and resistance to platinum-based chemotherapy. Cancer 2000;88:2584-9.
11. Valentinis B, Morrione A, Peruzzi F et al. Anti-apoptotic signaling of the IGF-1 receptor in fibroblasts following loss of matrix adhesion. Oncogene 1999;18:1827-36.
12. Kimura N, Dota K, Araya Y, Ishidate T, Ishizaka M. Scoring system foe differential diagnosis of malignant mesothelioma and reactive mesothelial cells on cytology specimens. Diagn Cytopathol 2009;37:885-90.
13. Toole BP. Hyaluronan: From extracellular glue to pericellular cue. Nature Rev Cancer 2004;4:528-39.
14. Vracko R. Basal lamina scaffold-anatomy and significance for maintenance of orderly tissue structure. Am J Pathol 1974;77:314-46.
15. Toole BP, Slomiany MG. Hyaluronan, CD44 and emmprin: partners in cancer cell chemoresistance. Drug Resist Updates 2008;11:110-21.