Pregnancy after successful cancer treatment: What needs to be considered?

Onkologie

Volumn 35, Issue 3, 2012, Pages 128-132

  Lawrenz, Barbara ^a   Henes, Melanie ^a   Neunhoeffer, Eva ^a   Fehm, Tanja ^a   Huebner, Stephanie ^a   Kanz, Lothar ^a   Marini, Patricia ^a   Mayer, Frank ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Chemotherapy; Desire for children; Pregnancy; Radiotherapy; Teratogenic effects; Young female cancer patients

Indexed keywords

BREAST CANCER; CANCER RADIOTHERAPY; CANCER SURVIVAL; CANCER SURVIVOR; CANCER THERAPY; CHILDHOOD CANCER; DISEASE COURSE; HUMAN; INTRAUTERINE GROWTH RETARDATION; LYMPHOMA; PERINATAL MORTALITY; PREGNANCY; PREMATURITY; RELAPSE; REVIEW; RISK FACTOR;

ABNORMALITIES, DRUG-INDUCED; ABNORMALITIES, RADIATION-INDUCED; ABORTION, SPONTANEOUS; ADULT; CHILD; FEMALE; FETAL GROWTH RETARDATION; HUMANS; NEOPLASMS; OBSTETRIC LABOR, PREMATURE; PREGNANCY; RISK; SURVIVORS;

EID: 84858677806     PISSN: 0378584X     EISSN: 14230240     Source Type: Journal    
DOI: 10.1159/000336830     Document Type: Review

References (47)

1. Jemal A, Clegg LX, Ward E, Ries LA, Wu X, Jamison PM, et al.: Annual report to the nation on the status of cancer, 1975-2001, with a special feature regarding survival. Cancer 2004;101:3-27. (Pubitemid 38812419)
2. Schover LR, Rybicke LA, Martin BA, Bringelsen KA: Having children after cancer. A pilot survey of survivors' attitude and experiences. Cancer 1999; 86:697-709. (Pubitemid 29379417)
3. Partridge AH, Ruddy KJ: Fertility and adjuvant treatment in young women with breast cancer. Breast 2007;16:175-181. (Pubitemid 350028573)
4. Reinmuth S, Liebeskind AK, Wickmann L, et al.: Having children after surviving cancer in childhood or adolescence-results of a Berlin survey. Klin Padiatr 2008;220:159-165. (Pubitemid 351758158)
5. Cvancarova M, Samuelsen SO, Magelssen H, Fossa SD: Reproduction rates after cancer treatment: experience from the Norwegian radium hospital. J Clin Oncol 2009;27:334-343.
6. Green DM, Whitton JA, Stovall M, et al.: Pregnancy outcome of female survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Am J Obstet Gynecol 2002;187:1070-1080. (Pubitemid 35178413)
7. Stensheim H, Cvancarova M, Møller B, Fossa SD: Pregnancy after adolescent and adult cancer: a population-based matched cohort study. Int J Cancer 2011;129:1225-1236.
8. www.ghsg.org/de/das-hodgkin-lymphom/prognose.
9. Saphner T, Tormey DC, Gray R: Annual hazard rates of recurrence for breast cancer after primary therapy. J Clin Oncol 1996;14:2738-2746. (Pubitemid 26329660)
10. Royal College of Obstetricians and Gynecologists: Guideline no. 12. www.rcog.org.uk/files/rcog-corp/upload-files/GT12-PregnancyBreastCancer2004. pdf.
11. EBCTCG: Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomized trials. Lancet 2005;365:1687-1717.
12. Kroman N, Jensen MB, Wohlfahrt J, Ejlertsen B: Pregnancy after treatment of breast cancer-a population-based study on behalf of the Danish Breast Cancer Cooperative Group. Acta Oncol 2008;47: 545-549. (Pubitemid 351878435)
13. Ives A, Saunders C, Bulsara M, Semmens J: Pregnancy after breast cancer: Population based study. BMJ 2007;334:194.
14. Largillier R, Savignoni A, Gligorov J, Chollet P, Guilhaume MN, Spielmann M, Luporsi E, Asselain B, Coudert B, Namer M: Prognostic role of pregnancy occurring before or after treatment of early breast cancer patients aged 35 years: A GET(N). A Working Group analysis. Cancer 2009;115:5155-5165.
15. Sankila R, Heinavaara S, Hakulinen T: Survival of breast cancer patients after subsequent term pregnancy: 'Healthy mother effect'. Am J Obstet Gynecol 1994;170:818-823. (Pubitemid 24224706)
16. Gelber S, Coates AS, Goldhirsch A, Castiglione-Gertsch M, Marini G, Lindtner J, Edelmann DZ, Gudgeon A, Harvey V, Gelber RD: Effect of pregnancy on overall survival after the diagnosis of early-stage breast cancer. J Clin Oncol 2001;19: 1671-1675. (Pubitemid 32230867)
17. Mueller BA, Simon MS, Deapen D, Kamineni A, Malone KE, Daling JR: Childbearing and survival after breast carcinoma in young women. Cancer 2003;98:1131-1140. (Pubitemid 37099897)
18. Azim HA Jr, Santoro L, Pavlidis N, Gelber S, Kroman N, Azim H, Peccatori FA: Safety of pregnancy following breast cancer diagnosis: a metaanalysis of 14 studies. Eur J Cancer 2010;47:74-83.
19. von Schoultz E, Johansson H, Wilking N, Rutqvist LE: Influence of prior and subsequent pregnancy on breast cancer prognosis. J Clin Oncol 1995;13:430-434.
20. Malamos NA, Stahopoulos GP, Keramopoulos A, et al.: Pregnancy and offspring after the appearance of breast cancer. Oncology 1996;53:471-475. (Pubitemid 26388388)
21. Sutton R, Budzar AU, Hortobagyi GN: Pregnancy and offspring after adjuvant chemotherapy in breast cancer patients. Cancer 1999;65:847-850.
22. Janerich DT: The fetal antigen hypothesis: Cancers and beyond. Med Hypotheses 2001;56:101-103. (Pubitemid 32052829)
23. Janerich DT: The influence of pregnancy on breast cancer risk: Is it endocrinological or immunological? Med Hypotheses 1980;6:1149-1155. (Pubitemid 11213916)
24. Surbone A, Petrek J: Pregnancy after breast cancer. The relationship of pregnancy to breast cancer development and progression. Crit Rev Oncol Hematol 1998;27:169-178. (Pubitemid 28278246)
25. Stensheim H, Møller B, van Dijk T, Fossa S: Cause-specific survival for women diagnosed with cancer during pregnancy or lactation: a registrybased cohort study. J Clin Oncol 2009;27:45-51.
26. Dodds L, Marrett LD, Tomkins DJ, et al.: Casecontrol study of congenital anomalies in children of cancer patients. BMJ 1993;307:164-168. (Pubitemid 23199979)
27. Byrne J, Rasmussen SA, Steinhorn SC, Connelly RR, Myers MH, Lynch CF, Flannery J, Austin DF, Holmes FF, Homes GE, Strong LC, Mulvihill JJ: Genetic disease in offspring of long-term survivors of childhood and adolescent cancer. Am J Hum Genet 1998;62:45-52. (Pubitemid 28093833)
28. Meistrich M, Byrne J: Genetic disease in offspring of long-term survivors of childhood and adolescent cancer treated with potentially mutagenic therapies. Am J Hum Genet 2002;70:1069-1071. (Pubitemid 34259328)
29. Berry DL, Theriault RL, Holmes FA, et al.: Management of breast cancer during pregnancy using a standardized protocol. J Clin Oncol 1999; 17:855-861. (Pubitemid 29109315)
30. Winter JF, Boice JD Jr, Frederiksen K, et al.: Radiotherapy for childhood cancer and risk for congenital malformations in offspring: a population-based cohort study. Clin Genet 2009;75:50-56.
31. Hawkins MM: Is there evidence of a therapy-related increase in germ cell mutation among childhood cancer survivors? J Natl Cancer Inst 1991; 83:1643-1650.
32. Sankila R, Olsen JH, Anderson H, et al.: Risk of cancer among offspring of childhood-cancer survivors. Association of the Nordic Cancer Registries and the Nordic Society of Paediatric Heamatology and Oncology. N Engl J Med 1998;338:1339-1344. (Pubitemid 28216662)
33. Mulvihill JJ, McKeen EA, Rosner F, et al.: Pregnancy outcome in cancer patients. Experience in a large cooperative group. Cancer 1987;60:1143-1150. (Pubitemid 17157234)
34. Fossa S, Magelssen H, Melve K, Jacobsen A, Langmark F, Skjoerven R: Parenthood in survivors after adulthood cancer and perinatal health in their offspring: a preliminary report. J Natl Cancer Inst 2005;34:77-82.
35. Velentgas P, Daling JR, Malone KE, Weiss NS, Williams MA, Self SG, Mueller BA: Pregnancy after breast carcinoma: Outcomes and influence on mortality. Cancer 1999;85:2424-2432. (Pubitemid 29244851)
36. Amant F, Deckers S, Van Calsteren K, et al.: Breast cancer in pregnancy: Recommendations of an international consensus meeting. Eur J Cancer 2010;46:3158-3168.
37. Wallace WH, Shalet SM, Hendry JH, et al.: Ovarian failure following abdominal irradiation in childhood: the radiosensitivity of the human oocyte. Br J Radiol 1989;62:995-998. (Pubitemid 19268427)
38. Sanders JE, Hawley J, Levy W, et al.: Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation. Blood 1996;87:3045-3052.
39. Holm K, Nysom K, Brocks V: Ultrasound B-mode changes in the uterus and ovaries and Doppler changes in the uterus after total body irradiation and allogeneic bone marrow transplantation in childhood. Bone Marrow Transplant 1999;23:259-263. (Pubitemid 29078339)
40. Bath LE, Wallace WH, Critchley HO: Late effects of the treatment of childhood cancer on the female reproductive system and the potential for fertility preservation. Br J Obstet Gynaecol 2002;109:107-114. (Pubitemid 37338030)
41. Green DM, Whitton JA, Stovall M, et al.: Pregnancy outcome of female survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Am J Obstet Gynecol 2002;187:1070-1080. (Pubitemid 35178413)
42. Critchley HO, Wallace WE: Impact of cancer treatment on uterine function. J Natl Cancer Inst Monogr 2005;34:64-68.
43. Green DM, Sklar CA, Boice JD Jr, Mulvihill JJ, Whitton JA, Stovall M, Yasui Y: Ovarian failure and reproductive outcomes after childhood cancer treatment: results from the Childhood Cancer Survivor Study. J Clin Oncol 2009;27:2374-2381.
44. Signorello LB, Mulvihill JJ, Green DM, Munro HM, Stovall M, Weathers RE, Mertens AC, Whitton JA, Robison LL, Boice JD Jr: Stillbirth and neonatal death in relation to radiation exposure before conception: a retrospective cohort study. Lancet 2010;376:624-630.
45. Winther JF, Boice JD Jr, Svendsen AL, Frederiksen K, Stovall M, Olsen JH: Spontaneous abortion in a Danish population-based cohort of childhood cancer survivors. Clin Oncol 2008;26: 4340-4346.
46. Lie Fong S, van den Heuvel-Eibrink MM, Eijkemans MJ, Schipper I, Hukkelhoven CW, Laven JS: Pregnancy outcome in female childhood cancer survivors. Hum Reprod 2010;25:1206-1212.
47. Boice JD, Tawn EJ, Winther JF, et al.: Genetic effects of radiotherapy for childhood cancer. Health Phys 2003;85:65-80. (Pubitemid 36706042)