Current concepts for rehabilitation and return to sport after knee articular cartilage repair in the athlete

Journal of Orthopaedic and Sports Physical Therapy

Volumn 42, Issue 3, 2012, Pages 254-273

  Mithoefer, Kai ^a   Hambly, Karen ^b   Logerstedt, David ^c   Ricci, Margherita ^d   Silvers, Holly ^e   Villa, Stefano Della ^d  

^a HARVARD VANGUARD MEDICAL ASSOCIATES   (United States)

^b UNIVERSITY OF KENT   (United Kingdom)

^c UNIVERSITY OF DELAWARE   (United States)

^d FIFA MEDICAL CENTRE OF EXCELLENCE   (Switzerland)

^e Santa Monica Orthopaedic and Sports Medicine Group   (United States)

Author keywords

ACI; Chondrocytes; Microfracture; OATS

Indexed keywords

EID: 84858669068     PISSN: 01906011     EISSN: None     Source Type: Journal    
DOI: 10.2519/jospt.2012.3665     Document Type: Review

References (193)

1. Adouni M, Shirazi-Adl A. Knee joint biomechanics in closed-kinetic-chain exercises. Comput Methods Biomech Biomed Engin. 2009;12:661-670. http://dx.doi.org/10.1080/10255840902828375
2. Ahmad CS, Kwak SD, Ateshian GA, Warden WH, Steadman JR, Mow VC. Effects of patellar tendon adhesion to the anterior tibia on knee mechanics. Am J Sports Med. 1998;26:715-724. (Pubitemid 28452799)
3. Alford JW, Lewis P, Kang RW, Cole BJ. Rapid progression of chondral disease in the lateral compartment of the knee following meniscectomy. Arthroscopy. 2005;21:1505-1509. http://dx.doi.org/10.1016/j.arthro.2005.03.036 (Pubitemid 41821032)
4. Alfredson H, Lorentzon R. Superior results with continuous passive motion compared to active motion after periosteal transplantation. A retrospective study of human patella cartilage defect treatment. Knee Surg Sports Traumatol Arthrosc. 1999;7:232-238.
5. Allen MK, Wellen MA, Hart DP, Glasoe WM. Rehabilitation following autologous chondrocyte implantation surgery: Case report using an accelerated weight-bearing protocol. Physiother Can. 2007;59:286-298. http://dx.doi.org/10. 3138/ptc.59.4.286
6. Aroen A, Loken S, Heir S, et al. Articular cartilage lesions in 993 consecutive knee arthroscopies. Am J Sports Med. 2004;32:211-215. (Pubitemid 38141444)
7. Arokoski JP, Jurvelin JS, Vaatainen U, Helminen HJ. Normal and pathological adaptations of articular cartilage to joint loading. Scand J Med Sci Sports. 2000;10:186-198.
8. Asik M, Ciftci F, Sen C, Erdil M, Atalar A. The microfracture technique for the treatment of full-thickness articular cartilage lesions of the knee: Midterm results. Arthroscopy. 2008;24:1214-1220. http://dx.doi.org/10.1016/j. arthro.2008.06.015
9. Axe MJ, Snyder-Mackler L. Operative and postoperative management of the knee. In: Wilmarth MA, ed. Orthopaedic Section Independent Study Course 15.3: Postoperative Management of Orthopaedic Surgeries. La Crosse, WI: APTA Inc; 2005.
10. Ayotte NW, Stetts DM, Keenan G, Greenway EH. Electromyographical analysis of selected lower extremity muscles during 5 unilateral weight-bearing exercises. J Orthop Sports Phys Ther. 2007;37:48-55. http://dx.doi.org/10.2519/ jospt.2007.2354
11. Baker V, Bennell K, Stillman B, Cowan S, Crossley K. Abnormal knee joint position sense in individuals with patellofemoral pain syndrome. J Orthop Res. 2002;20:208-214. http://dx.doi.org/10.1016/S0736-0266(01)00106-1 (Pubitemid 34218264)
12. Barber SD, Noyes FR, Mangine RE, McCloskey JW, Hartman W. Quantitative assessment of functional limitations in normal and anterior cruciate ligament-deficient knees. Clin Orthop Relat Res. 1990;255:204-214. (Pubitemid 20187450)
13. Barrack RL, Skinner HB, Buckley SL. Proprioception in the anterior cruciate deficient knee. Am J Sports Med. 1989;17:1-6. (Pubitemid 19059835)
14. Bartlett W, Skinner JA, Gooding CR, et al. Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: A prospective, randomised study. J Bone Joint Surg Br. 2005;87:640-645. http://dx.doi.org/10.1302/0301-620X.87B5.15905 (Pubitemid 40711636)
15. Bedi A, Feeley BT, Williams RJ, 3rd. Management of articular cartilage defects of the knee. J Bone Joint Surg Am. 2010;92:994-1009. http://dx.doi.org/10.2106/JBJS.I.00895
16. Bekkers JE, Inklaar M, Saris DB. Treatment selection in articular cartilage lesions of the knee: A systematic review. Am J Sports Med. 2009;37 Suppl 1:148S-155S. http://dx.doi.org/10.1177/0363546509351143
17. Brennan SL, Cicuttini FM, Pasco JA, et al. Does an increase in body mass index over 10 years affect knee structure in a population-based cohort study of adult women? Arthritis Res Ther. 2010;12:R139. http://dx.doi.org/10.1186/ar3078
18. Brittberg M, Lindahl A, Nilsson A, Ohlsson C, Isaksson O, Peterson L. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med. 1994;331:889-895. http://dx.doi.org/10.1056/ NEJM199410063311401 (Pubitemid 24299869)
19. Brophy RH, Rodeo SA, Barnes RP, Powell JW, Warren RF. Knee articular cartilage injuries in the National Football League: Epidemiology and treatment approach by team physicians. J Knee Surg. 2009;22:331-338.
20. Buchanan TS, Kim AW, Lloyd DG. Selective muscle activation following rapid varus/valgus perturbations at the knee. Med Sci Sports Exerc. 1996;28:870-876. (Pubitemid 26255910)
21. Bynum EB, Barrack RL, Alexander AH. Open versus closed chain kinetic exercises after anterior cruciate ligament reconstruction. A prospective randomized study. Am J Sports Med. 1995;23:401-406.
22. Chmielewski TL, Hurd WJ, Rudolph KS, Axe MJ, Snyder-Mackler L. Perturbation training improves knee kinematics and reduces muscle co-contraction after complete unilateral anterior cruciate ligament rupture. Phys Ther. 2005;85:740-749; discussion 750-754. (Pubitemid 41060365)
23. Chmielewski TL, Jones D, Day T, Tillman SM, Lentz TA, George SZ. The association of pain and fear of movement/reinjury with function during anterior cruciate ligament reconstruction rehabilitation. J Orthop Sports Phys Ther. 2008;38:746-753. http://dx.doi.org/10.2519/jospt.2008.2887
24. Chmielewski TL, Myer GD, Kauffman D, Tillman SM. Plyometric exercise in the rehabilitation of athletes: Physiological responses and clinical application. J Orthop Sports Phys Ther. 2006;36:308-319. http://dx.doi.org/10. 2519/jospt.2006.2013
25. Chmielewski TL, Stackhouse S, Axe MJ, Snyder- Mackler L. A prospective analysis of incidence and severity of quadriceps inhibition in a consecutive sample of 100 patients with complete acute anterior cruciate ligament rupture. J Orthop Res. 2004;22:925-930. http://dx.doi.org/10.1016/j.orthres.2004.01.007 (Pubitemid 39145106)
26. Chmielewski TL, Zeppieri G, Jr., Lentz TA, et al. Longitudinal changes in psychosocial factors and their association with knee pain and function after anterior cruciate ligament reconstruction. Phys Ther. 2011;91:1355-1366. http://dx.doi.org/10.2522/ptj.20100277
27. Cohen ZA, Roglic H, Grelsamer RP, et al. Patellofemoral stresses during open and closed kinetic chain exercises. An analysis using computer simulation. Am J Sports Med. 2001;29:480-487. (Pubitemid 32661366)
28. Creighton RA, Bach BR, Jr. Arthrofibrosis: Evaluation, prevention, and treatment. Tech Knee Surg. 2005;4:163-172.
29. de Jong SN, van Caspel DR, van Haeff MJ, Saris DB. Functional assessment and muscle strength before and after reconstruction of chronic anterior cruciate ligament lesions. Arthroscopy. 2007;23:21.e1-21.e11. http://dx.doi.org/10.1016/ j.arthro.2006.08.024
30. Delitto A, Rose SJ, McKowen JM, Lehman RC, Thomas JA, Shively RA. Electrical stimulation versus voluntary exercise in strengthening thigh musculature after anterior cruciate ligament surgery. Phys Ther. 1988;68:660-663.
31. Della Villa S, Boldrini L, Ricci M, et al. Clinical outcomes and return-to-sports participation of 50 soccer players after anterior cruciate ligament reconstruction through a sport-specific rehabilitation protocol. Sports Health. 2012;4:17-24. http://dx.doi.org/10.1177/1941738111417564
32. Della Villa S, Kon E, Filardo G, et al. Does intensive rehabilitation permit early return to sport without compromising the clinical outcome after arthroscopic autologous chondrocyte implantation in highly competitive athletes? Am J Sports Med. 2010;38:68-77. http://dx.doi.org/10.1177/0363546509348490
33. Deyle GD, Allison SC, Matekel RL, et al. Physical therapy treatment effectiveness for osteoarthritis of the knee: A randomized comparison of supervised clinical exercise and manual therapy procedures versus a home exercise program. Phys Ther. 2005;85:1301-1317. (Pubitemid 41746276)
34. Ding C, Cicuttini F, Scott F, Cooley H, Boon C, Jones G. Natural history of knee cartilage defects and factors affecting change. Arch Intern Med. 2006;166:651-658. http://dx.doi.org/10.1001/archinte.166.6.651
35. Ding C, Garnero P, Cicuttini F, Scott F, Cooley H, Jones G. Knee cartilage defects: Association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen breakdown. Osteoarthritis Cartilage. 2005;13:198-205. http://dx.doi.org/10.1016/j.joca. 2004.11.007 (Pubitemid 40277277)
36. Drawer S, Fuller CW. Propensity for osteoarthritis and lower limb joint pain in retired professional soccer players. Br J Sports Med. 2001;35:402-408. (Pubitemid 34025288)
37. Ebert JR, Robertson WB, Lloyd DG, Zheng MH, Wood DJ, Ackland T. Traditional vs accelerated approaches to post-operative rehabilitation following matrix-induced autologous chondrocyte implantation (MACI): Comparison of clinical, biomechanical and radiographic outcomes. Osteoarthritis Cartilage. 2008;16:1131-1140. http://dx.doi.org/10.1016/j.joca.2008.03.010
38. Eckstein F, Benichou O, Wirth W, et al. Magnetic resonance imaging-based cartilage loss in painful contralateral knees with and without radiographic joint space narrowing: data from the Osteoarthritis Initiative. Arthritis Rheum. 2009;61:1218-1225. http://dx.doi.org/10.1002/art.24791
39. Eckstein F, Lemberger B, Gratzke C, et al. In vivo cartilage deformation after different types of activity and its dependence on physical training status. Ann Rheum Dis. 2005;64:291-295. http://dx.doi.org/10.1136/ard.2004. 022400 (Pubitemid 40193629)
40. Eitzen I, Holm I, Risberg MA. Preoperative quadriceps strength is a significant predictor of knee function two years after anterior cruciate ligament reconstruction. Br J Sports Med. 2009;43:371-376. http://dx.doi.org/10. 1136/bjsm.2008.057059
41. Eitzen I, Moksnes H, Snyder-Mackler L, Risberg MA. A progressive 5-week exercise therapy program leads to significant improvement in knee function early after anterior cruciate ligament injury. J Orthop Sports Phys Ther. 2010;40:705-721. http://dx.doi.org/10.2519/jospt.2010.3345
42. Escamilla RF. Knee biomechanics of the dynamic squat exercise. Med Sci Sports Exerc. 2001;33:127-141. (Pubitemid 32064409)
43. Escamilla RF, Wickham R. Exercise-based conditioning and rehabilitation. In: Kolt GS, Snyder- Mackler L, eds. Physical Therapies in Sport and Exercise. London, UK: Churchill Livingstone; 2003:143-164.
44. Eskelinen AP, Visuri T, Larni HM, Ritsila V. Primary cartilage lesions of the knee joint in young male adults. Overweight as a predisposing factor. An arthroscopic study. Scand J Surg. 2004;93:229-233. (Pubitemid 39482301)
45. Fitzgerald GK, Axe MJ, Snyder-Mackler L. A decision- making scheme for returning patients to high-level activity with nonoperative treatment after anterior cruciate ligament rupture. Knee Surg Sports Traumatol Arthrosc. 2000;8:76-82.
46. Fitzgerald GK, Axe MJ, Snyder-Mackler L. The efficacy of perturbation training in nonoperative anterior cruciate ligament rehabilitation programs for physical active individuals. Phys Ther. 2000;80:128-140.
47. Fitzgerald GK, Lephart SM, Hwang JH, Wainner RS. Hop tests as predictors of dynamic knee stability. J Orthop Sports Phys Ther. 2001;31:588-597. (Pubitemid 32959742)
48. Fitzgerald JB, Jin M, Grodzinsky AJ. Shear and compression differentially regulate clusters of functionally related temporal transcription patterns in cartilage tissue. J Biol Chem. 2006;281:24095-24103. http://dx.doi.org/10.1074/ jbc.M510858200 (Pubitemid 44274184)
49. Flanigan DC, Harris JD, Trinh TQ, Siston RA, Brophy RH. Prevalence of chondral defects in athletes' knees: A systematic review. Med Sci Sports Exerc. 2010;42:1795-1801. http://dx.doi.org/10.1249/MSS.0b013e3181d9eea0
50. Foster C, Fitzgerald DJ, Spatz P. Stability of the blood lactate-heart rate relationship in competitive athletes. Med Sci Sports Exerc. 1999;31:578-582. (Pubitemid 29173752)
51. Geiser CF, O'Connor KM, Earl JE. Effects of isolated hip abductor fatigue on frontal plane knee mechanics. Med Sci Sports Exerc. 2010;42:535-545. http://dx.doi.org/10.1249/MSS.0b013e3181b7b227
52. Gemmiti CV, Guldberg RE. Shear stress magnitude and duration modulates matrix composition and tensile mechanical properties in engineered cartilaginous tissue. Biotechnol Bioeng. 2009;104:809-820. http://dx.doi.org/10.1002/bit. 22440
53. George SZ, Lentz TA, Zeppieri G, Lee D, Chmielewski TL. Analysis of shortened versions of the Tampa Scale for Kinesiophobia and pain catastrophizing scale for patients after anterior cruciate ligament reconstruction. Clin J Pain. 2012;28:73-80. http://dx.doi.org/10.1097/AJP.0b013e31822363f4
54. Gerber JP, Marcus RL, Dibble LE, Greis PE, Burks RT, LaStayo PC. Effects of early progressive eccentric exercise on muscle size and function after anterior cruciate ligament reconstruction: A 1-year follow-up study of a randomized clinical trial. Phys Ther. 2009;89:51-59. http://dx.doi.org/10.2522/ ptj.20070189
55. Gerber JP, Marcus RL, Dibble LE, Greis PE, Burks RT, Lastayo PC. Safety, feasibility, and efficacy of negative work exercise via eccentric muscle activity following anterior cruciate ligament reconstruction. J Orthop Sports Phys Ther. 2007;37:10-18. http://dx.doi.org/10.2519/jospt.2007.2362 (Pubitemid 46095377)
56. Gillogly SD, Myers TH, Reinold MM. Treatment of full-thickness chondral defects in the knee with autologous chondrocyte implantation. J Orthop Sports Phys Ther. 2006;36:751-764. http://dx.doi.org/10.2519/jospt.2006.2409 (Pubitemid 44563795)
57. Gobbi A, Francisco R. Factors affecting return to sports after anterior cruciate ligament reconstruction with patellar tendon and hamstring graft: A prospective clinical investigation. Knee Surg Sports Traumatol Arthrosc. 2006;14:1021-1028. http://dx.doi.org/10.1007/s00167-006-0050-9 (Pubitemid 44496644)
58. Gobbi A, Nunag P, Malinowski K. Treatment of full thickness chondral lesions of the knee with microfracture in a group of athletes. Knee Surg Sports Traumatol Arthrosc. 2005;13:213-221. http://dx.doi.org/10.1007/s00167-004-0499-3 (Pubitemid 40569105)
59. Grelsamer RP, Klein JR. The biomechanics of the patellofemoral joint. J Orthop Sports Phys Ther. 1998;28:286-298. (Pubitemid 28507346)
60. Grosset JF, Piscione J, Lambertz D, Perot C. Paired changes in electromechanical delay and musculo-tendinous stiffness after endurance or plyometric training. Eur J Appl Physiol. 2009;105:131-139. http://dx.doi.org/10. 1007/s00421-008-0882-8
61. Gudas R, Kalesinskas RJ, Kimtys V, et al. A prospective randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint in young athletes. Arthroscopy. 2005;21:1066-1075. http://dx.doi.org/10.1016/j. arthro.2005.06.018 (Pubitemid 41323870)
62. Hambly K, Bobic V, Wondrasch B, Van Assche D, Marlovits S. Autologous chondrocyte implantation postoperative care and rehabilitation: science and practice. Am J Sports Med. 2006;34:1020-1038. http://dx.doi.org/10.1177/ 0363546505281918 (Pubitemid 43725772)
63. Hangody L, Rathonyi GK, Duska Z, Vasarhelyi G, Fules P, Modis L. Autologous osteochondral mosaicplasty. Surgical technique. J Bone Joint Surg Am. 2004;86-A Suppl 1:65-72. (Pubitemid 38269056)
64. Harris JD, Brophy RH, Siston RA, Flanigan DC. Treatment of chondral defects in the athlete's knee. Arthroscopy. 2010;26:841-852. http://dx.doi.org/10.1016/j.arthro.2009.12.030
65. Harrison RA, Hillman M, Bulstrode S. Loading of the lower limb when walking partially immersed: Implications for clinical practice. Physiotherapy. 1992;78:164-166.
66. Hartigan E, Axe MJ, Snyder-Mackler L. Perturbation training prior to ACL reconstruction improves gait asymmetries in non-copers. J Orthop Res. 2009;27:724-729. http://dx.doi.org/10.1002/jor.20754
67. Hartigan EH, Axe MJ, Snyder-Mackler L. Time line for noncopers to pass return-to-sports criteria after anterior cruciate ligament reconstruction. J Orthop Sports Phys Ther. 2010;40:141-154. http://dx.doi.org/10.2519/jospt.2010. 3168
68. Hewett TE, Myer GD, Ford KR, et al. Biomechanical measures of neuromuscular control and valgus loading of the knee predict anterior cruciate ligament injury risk in female athletes: A prospective study. Am J Sports Med. 2005;33:492-501. http://dx.doi.org/10.1177/0363546504269591 (Pubitemid 40411154)
69. Hewett TE, Paterno MV, Myer GD. Strategies for enhancing proprioception and neuromuscular control of the knee. Clin Orthop Relat Res. 2002;402:76-94. (Pubitemid 35006581)
70. Hewett TE, Stroupe AL, Nance TA, Noyes FR. Plyometric training in female athletes. Decreased impact forces and increased hamstring torques. Am J Sports Med. 1996;24:765-773. (Pubitemid 26394162)
71. Hinterwimmer S, Krammer M, Krotz M, et al. Cartilage atrophy in the knees of patients after seven weeks of partial load bearing. Arthritis Rheum. 2004;50:2516-2520. http://dx.doi.org/10.1002/art.20378 (Pubitemid 39062712)
72. Howard JS, Mattacola CG, Romine SE, Lattermann C. Continuous passive motion, early weight bearing, and active motion following knee articular cartilage repair: Evidence for clinical practice. Cartilage. 2010;1:276-286. http://dx.doi.org/10.1177/1947603510368055
73. Hurtig MB, Fretz PB, Doige CE, Schnurr DL. Effects of lesion size and location on equine articular cartilage repair. Can J Vet Res. 1988;52:137-146.
74. Ikenoue T, Trindade MC, Lee MS, et al. Mechanoregulation of human articular chondrocyte aggrecan and type II collagen expression by intermittent hydrostatic pressure in vitro. J Orthop Res. 2003;21:110-116. http://dx.doi.org/10.1016/S0736-0266(02)00091-8 (Pubitemid 36157627)
75. Ingersoll CD, Grindstaff TL, Pietrosimone BG, Hart JM. Neuromuscular consequences of anterior cruciate ligament injury. Clin Sports Med. 2008;27:383-404. http://dx.doi.org/10.1016/j.csm.2008.03.004 (Pubitemid 351715399)
76. Irrgang JJ, Pezzullo D. Rehabilitation following surgical procedures to address articular cartilage lesions in the knee. J Orthop Sports Phys Ther. 1998;28:232-240. (Pubitemid 28470979)
77. Jackson DW, Lalor PA, Aberman HM, Simon TM. Spontaneous repair of full-thickness defects of articular cartilage in a goat model. A preliminary study. J Bone Joint Surg Am. 2001;83-A:53-64. (Pubitemid 32116108)
78. Jakobsen RB, Engebretsen L, Slauterbeck JR. An analysis of the quality of cartilage repair studies. J Bone Joint Surg Am. 2005;87:2232-2239. http://dx.doi.org/10.2106/JBJS.D.02904 (Pubitemid 41407548)
79. Jones G, Bennell K, Cicuttini FM. Effect of physical activity on cartilage development in healthy kids. Br J Sports Med. 2003;37:382-383. (Pubitemid 37260281)
80. Jones HP, Appleyard RC, Mahajan S, Murrell GA. Meniscal and chondral loss in the anterior cruciate ligament injured knee. Sports Med. 2003;33:1075-1089. (Pubitemid 37491484)
81. Kato T, Terashima T, Yamashita T, Hatanaka Y, Honda A, Umemura Y. Effect of low-repetition jump training on bone mineral density in young women. J Appl Physiol. 2006;100:839-843. http://dx.doi.org/10.1152/japplphysiol.00666.2005 (Pubitemid 43671538)
82. Kim KM, Croy T, Hertel J, Saliba S. Effects of neuromuscular electrical stimulation after anterior cruciate ligament reconstruction on quadriceps strength, function, and patient-oriented outcomes: A systematic review. J Orthop Sports Phys Ther. 2010;40:383-391. http://dx.doi.org/10.2519/jospt.2010.3184
83. Kish G, Modis L, Hangody L. Osteochondral mosaicplasty for the treatment of focal chondral and osteochondral lesions of the knee and talus in the athlete. Rationale, indications, techniques, and results. Clin Sports Med. 1999;18:45-66. (Pubitemid 29066059)
84. Kiviranta I, Tammi M, Jurvelin J, Arokoski J, Saamanen AM, Helminen HJ. Articular cartilage thickness and glycosaminoglycan distribution in the canine knee joint after strenuous running exercise. Clin Orthop Relat Res. 1992;283:302-308.
85. Kocher MS, Steadman JR, Briggs K, Zurakowski D, Sterett WI, Hawkins RJ. Determinants of patient satisfaction with outcome after anterior cruciate ligament reconstruction. J Bone Joint Surg Am. 2002;84-A:1560-1572. (Pubitemid 35014705)
86. Kreuz PC, Steinwachs M, Erggelet C, et al. Importance of sports in cartilage regeneration after autologous chondrocyte implantation: A prospective study with a 3-year follow-up. Am J Sports Med. 2007;35:1261-1268. http://dx.doi.org/10.1177/0363546507300693 (Pubitemid 47084201)
87. Kubo K, Morimoto M, Komuro T, Tsunoda N, Kanehisa H, Fukunaga T. Influences of tendon stiffness, joint stiffness, and electromyographic activity on jump performances using single joint. Eur J Appl Physiol. 2007;99:235-243. http://dx.doi.org/10.1007/s00421-006-0338-y (Pubitemid 46196060)
88. Kujala UM, Kettunen J, Paananen H, et al. Knee osteoarthritis in former runners, soccer players, weight lifters, and shooters. Arthritis Rheum. 1995;38:539-546.
89. Kuster MS. Exercise recommendations after total joint replacement: A review of the current literature and proposal of scientifically based guidelines. Sports Med. 2002;32:433-445. (Pubitemid 34620904)
90. Kvist J. Rehabilitation following anterior cruciate ligament injury: Current recommendations for sports participation. Sports Med. 2004;34:269-280. (Pubitemid 38534750)
91. Kvist J, Ek A, Sporrstedt K, Good L. Fear of re-injury: A hindrance for returning to sports after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2005;13:393-397. http://dx.doi.org/10.1007/s00167- 004-0591-8 (Pubitemid 40991801)
92. Lane Smith R, Trindade MC, Ikenoue T, et al. Effects of shear stress on articular chondrocyte metabolism. Biorheology. 2000;37:95-107. (Pubitemid 30353539)
93. LaStayo PC, Woolf JM, Lewek MD, Snyder- Mackler L, Reich T, Lindstedt SL. Eccentric muscle contractions: Their contribution to injury, prevention, rehabilitation, and sport. J Orthop Sports Phys Ther. 2003;33:557-571. (Pubitemid 38139796)
94. Lephart SM, Abt JP, Ferris CM, et al. Neuromuscular and biomechanical characteristic changes in high school athletes: A plyometric versus basic resistance program. Br J Sports Med. 2005;39:932-938. http://dx.doi.org/10.1136/ bjsm.2005.019083 (Pubitemid 41736357)
95. Lephart SM, Pincivero DM, Rozzi SL. Proprioception of the ankle and knee. Sports Med. 1998;25:149-155. (Pubitemid 28152013)
96. Levy AS, Lohnes J, Sculley S, LeCroy M, Garrett W. Chondral delamination of the knee in soccer players. Am J Sports Med. 1996;24:634-639. (Pubitemid 26314935)
97. Lewek M, Rudolph K, Axe M, Snyder-Mackler L. The effect of insufficient quadriceps strength on gait after anterior cruciate ligament reconstruction. Clin Biomech (Bristol, Avon). 2002;17:56-63. (Pubitemid 34098777)
98. Lin J, Li R, Kang X, Li H. Risk factors for radiographic tibiofemoral knee osteoarthritis: The Wuchuan Osteoarthritis Study. Int J Rheumatol. 2010;2010:385826. http://dx.doi.org/10.1155/2010/385826
99. Logerstedt DS, Snyder-Mackler L, Ritter RC, Axe MJ, Godges JJ. Knee stability and movement coordination impairments: knee ligament sprain. J Orthop Sports Phys Ther. 2010;40:A1-A37. http://dx.doi.org/10.2519/jospt.2010.0303
100. Lohmander LS, Roos H, Dahlberg L, Hoerrner LA, Lark MW. Temporal patterns of stromelysin- 1, tissue inhibitor, and proteoglycan fragments in human knee joint fluid after injury to the cruciate ligament or meniscus. J Orthop Res. 1994;12:21-28. http://dx.doi.org/10.1002/jor.1100120104 (Pubitemid 24070785)
101. Lorenz DS, Reiman MP. Performance enhancement in the terminal phases of rehabilitation. Sports Health. 2011;3:470-480. http://dx.doi.org/10.1177/ 1941738111415039
102. Mac Auley DC. Ice therapy: how good is the evidence? Int J Sports Med. 2001;22:379-384. (Pubitemid 32680893)
103. Manal TJ, Snyder-Mackler L. Practice guidelines for anterior cruciate ligament rehabilitation: A criterion-based rehabilitation progression. Oper Tech Orthop. 1996;6:190-196. (Pubitemid 126666390)
104. Mandelbaum BR, Browne JE, Fu F, et al. Articular cartilage lesions of the knee. Am J Sports Med. 1998;26:853-861. (Pubitemid 28555164)
105. Mandelbaum BR, Silvers HJ, Watanabe DS, et al. Effectiveness of a neuromuscular and proprioceptive training program in preventing anterior cruciate ligament injuries in female athletes: 2-year follow-up. Am J Sports Med. 2005;33:1003-1010. http://dx.doi.org/10.1177/0363546504272261 (Pubitemid 40917549)
106. Marcacci M, Kon E, Delcogliano M, Filardo G, Busacca M, Zaffagnini S. Arthroscopic autologous osteochondral grafting for cartilage defects of the knee: Prospective study results at a minimum 7-year follow-up. Am J Sports Med. 2007;35:2014-2021. http://dx.doi.org/10.1177/0363546507305455 (Pubitemid 350125800)
107. Marder RA, Hopkins G, Jr., Timmerman LA. Arthroscopic microfracture of chondral defects of the knee: A comparison of two postoperative treatments. Arthroscopy. 2005;21:152-158. http://dx.doi.org/10.1016/j.arthro.2004.10.009 (Pubitemid 40202781)
108. Mariani PP, Garofalo R, Margheritini F. Chondrolysis after partial lateral meniscectomy in athletes. Knee Surg Sports Traumatol Arthrosc. 2008;16:574-580. http://dx.doi.org/10.1007/s00167-008-0508-z
109. Markovic G, Dizdar D, Jukic I, Cardinale M. Reliability and factorial validity of squat and countermovement jump tests. J Strength Cond Res. 2004;18:551-555. (Pubitemid 39207775)
110. Markovic G, Mikulic P. Neuro-musculoskeletal and performance adaptations to lower-extremity plyometric training. Sports Med. 2010;40:859-895. http://dx.doi.org/10.2165/11318370-000000000-00000
111. Matthews P, St-Pierre DM. Recovery of muscle strength following arthroscopic meniscectomy. J Orthop Sports Phys Ther. 1996;23:18-26. (Pubitemid 26021779)
112. Mayr HO, Weig TG, Plitz W. Arthrofibrosis following ACL reconstruction-reasons and outcome. Arch Orthop Trauma Surg. 2004;124:518-522. http://dx.doi.org/10.1007/s00402-004-0718-x (Pubitemid 39462471)
113. McAdams TR, Mithoefer K, Scopp JM, Mandelbaum BR. Articular cartilage injury in athletes. Cartilage. 2010;1:165-179. http://dx.doi.org/10.1177/ 1947603509360210
114. McGinty G, Irrgang JJ, Pezzullo D. Biomechanical considerations for rehabilitation of the knee. Clin Biomech (Bristol, Avon). 2000;15:160-166. (Pubitemid 30069981)
115. Messner K, Maletius W. The long-term prognosis for severe damage to weight-bearing cartilage in the knee: A 14-year clinical and radiographic follow-up in 28 young athletes. Acta Orthop Scand. 1996;67:165-168. (Pubitemid 26140405)
116. Mikkelsen C, Werner S, Eriksson E. Closed kinetic chain alone compared to combined open and closed kinetic chain exercises for quadriceps strengthening after anterior cruciate ligament reconstruction with respect to return to sports: A prospective matched follow-up study. Knee Surg Sports Traumatol Arthrosc. 2000;8:337-342.
117. Minas T, Peterson L. Advanced techniques in autologous chondrocyte transplantation. Clin Sports Med. 1999;18:13-44. (Pubitemid 29066058)
118. Mithoefer K, Gill TJ, Cole BJ, Williams RJ, Mandelbaum BR. Clinical outcome and return to competition after microfracture in the athlete's knee: An evidence-based systematic review. Cartilage. 2010;1:113-120. http://dx.doi.org/10.1177/1947603510366576
119. Mithoefer K, Hambly K, Della Villa S, Silvers H, Mandelbaum BR. Return to sports participation after articular cartilage repair in the knee: scientific evidence. Am J Sports Med. 2009;37 Suppl 1:167S-176S. http://dx.doi.org/10.1177/ 0363546509351650
120. Mithoefer K, McAdams T, Williams RJ, Kreuz PC, Mandelbaum BR. Clinical efficacy of the microfracture technique for articular cartilage repair in the knee: An evidence-based systematic analysis. Am J Sports Med. 2009;37:2053-2063. http://dx.doi.org/10.1177/0363546508328414
121. Mithoefer K, Minas T, Peterson L, Yeon H, Micheli LJ. Functional outcome of knee articular cartilage repair in adolescent athletes. Am J Sports Med. 2005;33:1147-1153. http://dx.doi.org/10.1177/0363546504274146 (Pubitemid 41045186)
122. Mithoefer K, Peterson L, Mandelbaum BR, Minas T. Articular cartilage repair in soccer players with autologous chondrocyte transplantation: functional outcome and return to competition. Am J Sports Med. 2005;33:1639-1646. http://dx.doi.org/10.1177/0363546505275647 (Pubitemid 41546736)
123. Mithoefer K, Saris DBF, Farr J, et al. Guidelines for the design and conduct of clinical studies in knee articular cartilage repair: International Cartilage Repair Society recommendations based on current scientific evidence and standards of clinical care. Cartilage. 2011;2:100-121. http://dx.doi.org/10. 1177/1947603510392913
124. Mithoefer K, Williams RJ, 3rd, Warren RF, et al. Chondral resurfacing of articular cartilage defects in the knee with the microfracture technique. Surgical technique. J Bone Joint Surg Am. 2006;88 Suppl 1 Pt 2:294-304. http://dx.doi.org/10.2106/JBJS.F.00292
125. Mithoefer K, Williams RJ, 3rd, Warren RF, et al. The microfracture technique for the treatment of articular cartilage lesions in the knee. A prospective cohort study. J Bone Joint Surg Am. 2005;87:1911-1920. http://dx.doi.org/10.2106/JBJS.D.02846 (Pubitemid 41279120)
126. Mithoefer K, Williams RJ, 3rd, Warren RF, Wickiewicz TL, Marx RG. High-impact athletics after knee articular cartilage repair: A prospective evaluation of the microfracture technique. Am J Sports Med. 2006;34:1413-1418. http://dx.doi.org/10.1177/0363546506288240
127. Mouritzen U, Christgau S, Lehmann HJ, Tanko LB, Christiansen C. Cartilage turnover assessed with a newly developed assay measuring collagen type II degradation products: Influence of age, sex, menopause, hormone replacement therapy, and body mass index. Ann Rheum Dis. 2003;62:332-336. (Pubitemid 36363439)
128. Murphy SL, Smith DM, Clauw DJ, Alexander NB. The impact of momentary pain and fatigue on physical activity in women with osteoarthritis. Arthritis Rheum. 2008;59:849-856. http://dx.doi.org/10.1002/art.23710 (Pubitemid 351847568)
129. Myer GD, Ford KR, Brent JL, Hewett TE. The effects of plyometric vs. dynamic stabilization and balance training on power, balance, and landing force in female athletes. J Strength Cond Res. 2006;20:345-353. http://dx.doi.org/10. 1519/R-17955.1 (Pubitemid 43910681)
130. Myer GD, Ford KR, McLean SG, Hewett TE. The effects of plyometric versus dynamic stabilization and balance training on lower extremity biomechanics. Am J Sports Med. 2006;34:445-455. http://dx.doi.org/10.1177/0363546505281241 (Pubitemid 43260582)
131. Myer GD, Ford KR, Palumbo JP, Hewett TE. Neuromuscular training improves performance and lower-extremity biomechanics in female athletes. J Strength Cond Res. 2005;19:51-60. http://dx.doi.org/10.1519/13643.1 (Pubitemid 40417254)
132. Myer GD, Paterno MV, Ford KR, Hewett TE. Neuromuscular training techniques to target deficits before return to sport after anterior cruciate ligament reconstruction. J Strength Cond Res. 2008;22:987-1014. http://dx.doi.org/10.1519/JSC.0b013e31816a86cd
133. Myer GD, Paterno MV, Ford KR, Quatman CE, Hewett TE. Rehabilitation after anterior cruciate ligament reconstruction: Criteria-based progression through the return-to-sport phase. J Orthop Sports Phys Ther. 2006;36:385-402. http://dx.doi.org/10.2519/jospt.2006.2222 (Pubitemid 43846232)
134. Myer GD, Schmitt LC, Brent JL, et al. Utilization of modified NFL combine testing to identify functional deficits in athletes following ACL reconstruction. J Orthop Sports Phys Ther. 2011;41:377-387. http://dx.doi.org/ 10.2519/jospt.2011.3547
135. Myklebust G, Bahr R. Return to play guidelines after anterior cruciate ligament surgery. Br J Sports Med. 2005;39:127-131. http://dx.doi.org/10.1136/ bjsm.2004.010900 (Pubitemid 40314905)
136. Nugent-Derfus GE, Takara T, O'Neill JK, et al. Continuous passive motion applied to whole joints stimulates chondrocyte biosynthesis of PRG4. Osteoarthritis Cartilage. 2007;15:566-574. http://dx.doi.org/10.1016/j.joca. 2006.10.015 (Pubitemid 46667714)
137. Palmieri RM, Ingersoll CD, Edwards JE, et al. Arthrogenic muscle inhibition is not present in the limb contralateral to a simulated knee joint effusion. Am J Phys Med Rehabil. 2003;82:910-916. http://dx.doi.org/10.1097/01. PHM.0000098045.04883.02 (Pubitemid 37486304)
138. Palmieri-Smith RM, Thomas AC, Wojtys EM. Maximizing quadriceps strength after ACL reconstruction. Clin Sports Med. 2008;27:405-424. http://dx.doi.org/ 10.1016/j.csm.2008.02.001 (Pubitemid 351720990)
139. Paterno MV, Schmitt LC, Ford KR, et al. Biomechanical measures during landing and postural stability predict second anterior cruciate ligament injury after anterior cruciate ligament reconstruction and return to sport. Am J Sports Med. 2010;38:1968-1978. http://dx.doi.org/10.1177/0363546510376053
140. Paulos LE, Rosenberg TD, Drawbert J, Manning J, Abbott P. Infrapatellar contracture syndrome. An unrecognized cause of knee stiffness with patella entrapment and patella infera. Am J Sports Med. 1987;15:331-341. (Pubitemid 17125865)
141. Perlman AI, Sabina A, Williams AL, Njike VY, Katz DL. Massage therapy for osteoarthritis of the knee: A randomized controlled trial. Arch Intern Med. 2006;166:2533-2538. http://dx.doi.org/10.1001/archinte.166.22.2533 (Pubitemid 44913239)
142. Petsche TS, Hutchinson MR. Loss of extension after reconstruction of the anterior cruciate ligament. J Am Acad Orthop Surg. 1999;7:119-127.
143. Piasecki DP, Spindler KP, Warren TA, Andrish JT, Parker RD. Intraarticular injuries associated with anterior cruciate ligament tear: findings at ligament reconstruction in high school and recreational athletes. An analysis of sex-based differences. Am J Sports Med. 2003;31:601-605. (Pubitemid 36875395)
144. Powers CM. The influence of abnormal hip mechanics on knee injury: A biomechanical perspective. J Orthop Sports Phys Ther. 2010;40:42-51. http://dx.doi.org/10.2519/jospt.2010.3337
145. Powers CM. The influence of altered lowerextremity kinematics on patellofemoral joint dysfunction: A theoretical perspective. J Orthop Sports Phys Ther. 2003;33:639-646. (Pubitemid 38139803)
146. Raynor MC, Pietrobon R, Guller U, Higgins LD. Cryotherapy after ACL reconstruction: A metaanalysis. J Knee Surg. 2005;18:123-129.
147. Reinold MM, Wilk KE, Macrina LC, Dugas JR, Cain EL. Current concepts in the rehabilitation following articular cartilage repair procedures in the knee. J Orthop Sports Phys Ther. 2006;36:774-794. http://dx.doi.org/10.2519/jospt. 2006.2228 (Pubitemid 44563797)
148. Risberg MA, Ekeland A. Assessment of functional tests after anterior cruciate ligament surgery. J Orthop Sports Phys Ther. 1994;19:212-217. (Pubitemid 24090054)
149. Risberg MA, Holm I, Myklebust G, Engebretsen L. Neuromuscular training versus strength training during first 6 months after anterior cruciate ligament reconstruction: A randomized clinical trial. Phys Ther. 2007;87:737-750. http://dx.doi.org/10.2522/ptj.20060041 (Pubitemid 46870399)
150. Robertson CM, Warren RF, Rodeo SA, Wickiewicz TL, Williams RJ, 3rd. Return to athletics after fresh osteochondral allografting procedures. Annual Meeting of the American Orthopaedic Society for Sports Medicine, July 17, 2010. Providence, RI: American Orthopaedic Society for Sports Medicine.
151. Rodrigo JJ, Steadman JR, Silliman JF, Fulstone HA. Improvement of full-thickness chondral defect healing in the human knee after debridement and microfracture using continuous passive motion. Am J Knee Surg. 1994;7:109-116.
152. Roi GS, Creta D, Nanni G, Marcacci M, Zaffagnini S, Snyder-Mackler L. Return to official Italian First Division soccer games within 90 days after anterior cruciate ligament reconstruction: A case report. J Orthop Sports Phys Ther. 2005;35:52-61; discussion 61-66. http://dx.doi.org/10.2519/jospt.2005.1583 (Pubitemid 40276839)
153. Roos H. Are there long-term sequelae from soccer? Clin Sports Med. 1998;17:819-831. (Pubitemid 28476030)
154. Salter RB. The biologic concept of continuous passive motion of synovial joints. The first 18 years of basic research and its clinical application. Clin Orthop Relat Res. 1989;242:12-25. (Pubitemid 19131524)
155. Salter RB, Simmonds DF, Malcolm BW, Rumble EJ, MacMichael D, Clements ND. The biological effect of continuous passive motion on the healing of full-thickness defects in articular cartilage. An experimental investigation in the rabbit. J Bone Joint Surg Am. 1980;62:1232-1251. (Pubitemid 11207772)
156. Saris DB, Vanlauwe J, Victor J, et al. Treatment of symptomatic cartilage defects of the knee: Characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture. Am J Sports Med. 2009;37 Suppl 1:10S-19S. http://dx.doi.org/10.1177/ 0363546509350694
157. Schindler OS, Scott WN. Basic kinematics and biomechanics of the patello-femoral joint. Part 1: The native patella. Acta Orthop Belg. 2011;77:421-431.
158. Shapiro F, Koide S, Glimcher MJ. Cell origin and differentiation in the repair of full-thickness defects of articular cartilage. J Bone Joint Surg Am. 1993;75:532-553. (Pubitemid 23171742)
159. Shelbourne KD, Johnson GE. Outpatient surgical management of arthrofibrosis after anterior cruciate ligament surgery. Am J Sports Med. 1994;22:192-197. (Pubitemid 24099335)
160. Shelbourne KD, Klotz C. What I have learned about the ACL: utilizing a progressive rehabilitation scheme to achieve total knee symmetry after anterior cruciate ligament reconstruction. J Orthop Sci. 2006;11:318-325. http://dx.doi.org/10.1007/s00776-006-1007-z (Pubitemid 43806843)
161. Shelbourne KD, Patel DV, Martini DJ. Classification and management of arthrofibrosis of the knee after anterior cruciate ligament reconstruction. Am J Sports Med. 1996;24:857-862. (Pubitemid 26394176)
162. Shelbourne KD, Vanadurongwan B, Gray T. Primary anterior cruciate ligament reconstruction using contralateral patellar tendon autograft. Clin Sports Med. 2007;26:549-565. http://dx.doi.org/10.1016/j.csm.2007.06.008 (Pubitemid 47503516)
163. Shelbourne KD, Wilckens JH, Mollabashy A, DeCarlo M. Arthrofibrosis in acute anterior cruciate ligament reconstruction. The effect of timing of reconstruction and rehabilitation. Am J Sports Med. 1991;19:332-336.
164. Shields RK, Madhavan S, Gregg E, et al. Neuromuscular control of the knee during a resisted single-limb squat exercise. Am J Sports Med. 2005;33:1520-1526. http://dx.doi.org/10.1177/0363546504274150 (Pubitemid 41393106)
165. Shortkroff S, Barone L, Hsu HP, et al. Healing of chondral and osteochondral defects in a canine model: The role of cultured chondrocytes in regeneration of articular cartilage. Biomaterials. 1996;17:147-154. (Pubitemid 26031370)
166. Snyder-Mackler L, Delitto A, Bailey SL, Stralka SW. Strength of the quadriceps femoris muscle and functional recovery after reconstruction of the anterior cruciate ligament. A prospective, randomized clinical trial of electrical stimulation. J Bone Joint Surg Am. 1995;77:1166-1173.
167. Snyder-Mackler L, Delitto A, Stralka SW, Bailey SL. Use of electrical stimulation to enhance recovery of quadriceps femoris muscle force production in patients following anterior cruciate ligament reconstruction. Phys Ther. 1994;74:901-907. (Pubitemid 24297979)
168. Spencer JD, Hayes KC, Alexander IJ. Knee joint effusion and quadriceps reflex inhibition in man. Arch Phys Med Rehabil. 1984;65:171-177. (Pubitemid 14174557)
169. Steadman JR, Briggs KK, Rodrigo JJ, Kocher MS, Gill TJ, Rodkey WG. Outcomes of microfracture for traumatic chondral defects of the knee: Average 11-year follow-up. Arthroscopy. 2003;19:477-484. http://dx.doi.org/10.1053/jars. 2003.50112 (Pubitemid 36560399)
170. Steadman JR, Miller BS, Karas SG, Schlegel TF, Briggs KK, Hawkins RJ. The microfracture technique in the treatment of full-thickness chondral lesions of the knee in National Football League players. J Knee Surg. 2003;16:83-86.
171. Stoddart MJ, Ettinger L, Hauselmann HJ. Enhanced matrix synthesis in de novo, scaffold free cartilage-like tissue subjected to compression and shear. Biotechnol Bioeng. 2006;95:1043-1051. http://dx.doi.org/10.1002/bit.21052 (Pubitemid 44901319)
172. St-Pierre DM, Laforest S, Paradis S, et al. Isokinetic rehabilitation after arthroscopic meniscectomy. Eur J Appl Physiol Occup Physiol. 1992;64:437-443.
173. Strauss EJ, Barker JU, Kercher JS, Cole BJ, Mithoefer K. Augmentation strategies following the microfracture technique for repair of focal chondral defects. Cartilage. 2010;1:145-152. http://dx.doi.org/10.1177/1947603510366718
174. Sturgill LP, Snyder-Mackler L, Manal TJ, Axe MJ. Interrater reliability of a clinical scale to assess knee joint effusion. J Orthop Sports Phys Ther. 2009;39:845-849. http://dx.doi.org/10.2519/jospt.2009.3143
175. Tagesson S, Oberg B, Good L, Kvist J. A comprehensive rehabilitation program with quadriceps strengthening in closed versus open kinetic chain exercise in patients with anterior cruciate ligament deficiency: A randomized clinical trial evaluating dynamic tibial translation and muscle function. Am J Sports Med. 2008;36:298-307. http://dx.doi.org/10.1177/0363546507307867
176. Tew S, Redman S, Kwan A, et al. Differences in repair responses between immature and mature cartilage. Clin Orthop Relat Res. 2001;S142-152. (Pubitemid 32954020)
177. Thambyah A, Goh JC, De SD. Contact stresses in the knee joint in deep flexion. Med Eng Phys. 2005;27:329-335. http://dx.doi.org/10.1016/j.medengphy. 2004.09.002 (Pubitemid 40488774)
178. Thomee P, Wahrborg P, Borjesson M, Thomee R, Eriksson BI, Karlsson J. A new instrument for measuring self-efficacy in patients with an anterior cruciate ligament injury. Scand J Med Sci Sports. 2006;16:181-187. http://dx.doi.org/10. 1111/j.1600-0838.2005.00472.x (Pubitemid 43653860)
179. Thomee P, Wahrborg P, Borjesson M, Thomee R, Eriksson BI, Karlsson J. A randomized, controlled study of a rehabilitation model to improve knee-function self-efficacy with ACL injury. J Sport Rehabil. 2010;19:200-213.
180. Van Assche D, Van Caspel D, Vanlauwe J, et al. Physical activity levels after characterized chondrocyte implantation versus microfracture in the knee and the relationship to objective functional outcome with 2-year follow-up. Am J Sports Med. 2009;37 Suppl 1:42S-49S. http://dx.doi.org/10.1177/0363546509350296
181. Walczak BE, McCulloch PC, Kang RW, Zelazny A, Tedeschi F, Cole BJ. Abnormal findings on knee magnetic resonance imaging in asymptomatic NBA players. J Knee Surg. 2008;21:27-33.
182. Wang Y, Wluka AE, English DR, et al. Body composition and knee cartilage properties in healthy, community-based adults. Ann Rheum Dis. 2007;66:1244-1248. http://dx.doi.org/10.1136/ard.2006.064352 (Pubitemid 47309745)
183. Webster KE, Feller JA, Lambros C. Development and preliminary validation of a scale to measure the psychological impact of returning to sport following anterior cruciate ligament reconstruction surgery. Phys Ther Sport. 2008;9:9-15. http://dx.doi.org/10.1016/j.ptsp.2007.09.003 (Pubitemid 351176733)
184. Wei X, Rasanen T, Messner K. Maturationrelated compressive properties of rabbit knee articular cartilage and volume fraction of subchondral tissue. Osteoarthritis Cartilage. 1998;6:400-409. http://dx.doi.org/10.1053/joca.1998. 0143 (Pubitemid 28529797)
185. Widuchowski W, Widuchowski J, Trzaska T. Articular cartilage defects: study of 25,124 knee arthroscopies. Knee. 2007;14:177-182. http://dx.doi.org/10. 1016/j.knee.2007.02.001 (Pubitemid 46695821)
186. Wilk KE, Escamilla RF, Fleisig GS, Barrentine SW, Andrews JR, Boyd ML. A comparison of tibiofemoral joint forces and electromyographic activity during open and closed kinetic chain exercises. Am J Sports Med. 1996;24:518-527. (Pubitemid 26306941)
187. Wilk KE, Romaniello WT, Soscia SM, Arrigo CA, Andrews JR. The relationship between subjective knee scores, isokinetic testing, and functional testing in the ACL-reconstructed knee. J Orthop Sports Phys Ther. 1994;20:60-73. (Pubitemid 24226521)
188. Williams GN, Chmielewski T, Rudolph K, Buchanan TS, Snyder-Mackler L. Dynamic knee stability: Current theory and implications for clinicians and scientists. J Orthop Sports Phys Ther. 2001;31:546-566. (Pubitemid 32959739)
189. Williams JM, Moran M, Thonar EJ, Salter RB. Continuous passive motion stimulates repair of rabbit knee articular cartilage after matrix proteoglycan loss. Clin Orthop Relat Res. 1994;304:252-262. (Pubitemid 24230693)
190. Wondrasch B, Zak L, Welsch GH, Marlovits S. Effect of accelerated weightbearing after matrix-associated autologous chondrocyte implantation on the femoral condyle on radiographic and clinical outcome after 2 years: A prospective, randomized controlled pilot study. Am J Sports Med. 2009;37 Suppl 1:88S-96S. http://dx.doi.org/10.1177/0363546509351272
191. Wong M, Carter DR. Articular cartilage functional histomorphology and mechanobiology: A research perspective. Bone. 2003;33:1-13. (Pubitemid 36952683)
192. Wright RW, Preston E, Fleming BC, et al. A systematic review of anterior cruciate ligament reconstruction rehabilitation: Part II: open versus closed kinetic chain exercises, neuromuscular electrical stimulation, accelerated rehabilitation, and miscellaneous topics. J Knee Surg. 2008;21:225-234.
193. Zheng N, Fleisig GS, Escamilla RF, Barrentine SW. An analytical model of the knee for estimation of internal forces during exercise. J Biomech. 1998;31:963-967. (Pubitemid 28529574)