Neuroimaging in parkinson's disease: From pathology to diagnosis

Parkinsonism and Related Disorders

Volumn 18, Issue SUPPL. 1, 2012, Pages

  Stoessl, A Jon ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Autonomic dysfunction; Biomarkers; Diagnostic tests; Dopamine; Hyposmia; Pathogenesis; Preclinical detection; REM sleep behaviour disorder

Indexed keywords

6 FLUORODOPAMINE F 18; AMYLOID PROTEIN; APOLIPOPROTEIN E4; BIOLOGICAL MARKER; CHOLINESTERASE; DIHYDROTETRABENAZINE C 11; DOPAMINE; DOPAMINE RECEPTOR STIMULATING AGENT; LEVODOPA; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE C 11; RADIOISOTOPE; UNCLASSIFIED DRUG;

ARTICLE; AUTONOMIC DENERVATION; AUTONOMIC INNERVATION; BODY EQUILIBRIUM; BRADYKINESIA; BRAIN SCINTISCANNING; CHROMOSOME 17; CLINICAL FEATURE; CONSTIPATION; DEMENTIA; DEPRESSION; DIAGNOSTIC TEST; DIFFUSION TENSOR IMAGING; DISEASE COURSE; DOPAMINE DEFICIENCY; DOPAMINE TRANSPORTER SCANNING; ESSENTIAL TREMOR; FRACTIONAL ANISOTROPY; FRONTOTEMPORAL DEMENTIA; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE MUTATION; GLUCOSE METABOLISM; HETEROZYGOSITY; HUMAN; HYPOSMIA; LEWY BODY; NERVE CELL DEGENERATION; NEUROIMAGING; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; PARASOMNIA; PARKINSON DISEASE; PARKINSONISM; PEDUNCULOPONTINE TEGMENTAL NUCLEUS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUALITY OF LIFE; RISK FACTOR; SHY DRAGER SYNDROME; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SMELLING DISORDER; SUBSTANTIA NIGRA;

EID: 84858668900     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/s1353-8020(11)70019-0     Document Type: Article

References (32)

1. Vaillancourt DE, Spraker MB, Prodoehl J, Abraham I, Corcos DM, Zhou XJ, et al. High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease. Neurology 2009 Apr 21;72(16):1378-84.
2. Peran P, Cherubini A, Assogna F, Piras F, Quattrocchi C, Peppe A, et al. Magnetic resonance imaging markers of Parkinson's disease nigrostriatal signature. Brain 2010 Nov;133(11):3423-33.
3. Takeda A, Saito N, Baba T, Kikuchi A, Sugeno N, Kobayashi M, et al. Functional imaging studies of hyposmia in Parkinson's disease. J Neurol Sci 2010 Feb 15; 289(1-2):36-9.
4. Bohnen NI, Muller ML, Kotagal V, Koeppe RA, Kilbourn MA, Albin RL, et al. Olfactory dysfunction, central cholinergic integrity and cognitive impairment in Parkinson's disease. Brain 2010 Jun;133(Pt 6):1747-54.
5. Boileau I, Warsh JJ, Guttman M, Saint-Cyr JA, McCluskey T, Rusjan P, et al. Elevated serotonin transporter binding in depressed patients with Parkinson's disease: a preliminary PET study with [11C]DASB. Mov Disord 2008 Sep 15;23(12):1776-80.
6. Albin RL, Koeppe RA, Bohnen NI, Wernette K, Kilbourn MA, Frey KA. Spared caudal brainstem SERT binding in early Parkinson's disease. J Cereb Blood Flow Metab 2008 Mar;28(3):441-4.
7. Albin RL, Koeppe RA, Chervin RD, Consens FB, Wernette K, Frey KA, et al. Decreased striatal dopaminergic innervation in REM sleep behavior disorder. Neurology 2000 Nov 14;55(9):1410-2.
8. Iranzo A, Valldeoriola F, Lomena F, Molinuevo JL, Serradell M, Salamero M, et al. Serial dopamine transporter imaging of nigrostriatal function in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study. Lancet Neurol 2011 Sep;10(9):797-805.
9. Unger MM, Belke M, Menzler K, Heverhagen JT, Keil B, Stiasny-Kolster K, et al. Diffusion tensor imaging in idiopathic REM sleep behavior disorder reveals microstructural changes in the brainstem, substantia nigra, olfactory region, and other brain regions. Sleep 2010 Jun;33(6):767-73.
10. Kashihara K, Imamura T, Shinya T. Cardiac 123I-MIBG uptake is reduced more markedly in patients with REM sleep behavior disorder than in those with early stage Parkinson's disease. Parkinsonism Relat Disord 2010 May;16(4):252-5.
11. Goldstein DS, Holmes C, Sewell L, Park MY, Sharabi Y. Sympathetic noradrenergic before striatal dopaminergic denervation: relevance to Braak staging of synucleinopathy. Clin Auton Res 2011 Jul 28.
12. Antonini A, Leenders KL, Vontobel P, Maguire RP, Missimer J, Psylla M, et al. Complementary PET studies of striatal neuronal function in the differential diagnosis between multiple system atrophy and Parkinson's disease. Brain 1997;120:2187-95.
13. Yoshita M. Differentiation of idiopathic Parkinson's disease from striatonigral degeneration and progressive supranuclear palsy using iodine-123 metaiodobenzylguanidine myocardial scintigraphy. J Neurol Sci 1998 Feb 18;155(1): 60-7.
14. Ma Y, Huang C, Dyke JP, Pan H, Alsop D, Feigin A, et al. Parkinson's disease spatial covariance pattern: noninvasive quantification with perfusion MRI. J Cereb Blood Flow Metab 2010 Mar;30(3):505-9.
15. Tang CC, Poston KL, Eckert T, Feigin A, Frucht S, Gudesblatt M, et al. Differential diagnosis of parkinsonism: a metabolic imaging study using pattern analysis. Lancet Neurol 2010 Feb;9(2):149-58.
16. Sossi V, Fuente-Fernandez R, Nandhagopal R, Schulzer M, McKenzie J, Ruth TJ, et al. Dopamine turnover increases in asymptomatic LRRK2 mutations carriers. Mov Disord 2010 Dec 15;25(16):2717-23.
17. Khan NL, Scherfler C, Graham E, Bhatia KP, Quinn N, Lees AJ, et al. Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation. Neurology 2005 Jan 11;64(1):134-6.
18. Khan NL, Valente EM, Bentivoglio AR, Wood NW, Albanese A, Brooks DJ, et al. Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: an 18F-dopa PET study. Ann Neurol 2002 Dec;52(6):849-53.
19. Vingerhoets FJG, Schulzer M, Calne DB, Snow BJ. Which clinical sign of Parkinson's disease best reflects the nigrostriatal lesion? Ann Neurol 1997;41:58-64.
20. Doder M, Rabiner EA, Turjanski N, Lees AJ, Brooks DJ. Tremor in Parkinson's disease and serotonergic dysfunction: an 11C-WAY 100635 PET study. Neurology 2003 Feb 25;60(4):601-5.
21. Nandhagopal R, Kuramoto L, Schulzer M, Mak E, Cragg J, Lee CS, et al. Longitudinal progression of sporadic Parkinson's disease: a multi-tracer positron emission tomography study. Brain 2009 Nov;132(Pt 11):2970-9.
22. de la Fuente-Fernandez R, Schulzer M, Kuramoto L, Cragg J, Ramachandiran N, Au WL, et al. Age-specific progression of nigrostriatal dysfunction in Parkinson's disease. Ann Neurol 2011 May;69(5):803-10.
23. Huang C, Tang C, Feigin A, Lesser M, Ma Y, Pourfar M, et al. Changes in network activity with the progression of Parkinson's disease. Brain 2007 Jul;130(Pt 7):1834-46.
24. ZhanW, Kang GA, Glass GA, Zhang Y, Shirley C, Millin R, et al. Regional alterations of brain microstructure in parkinson's disease using diffusion tensor imaging. Mov Disord 2011 Aug 17.
25. Martin WR, Wieler M, Gee M. Midbrain iron content in early Parkinson disease: a potential biomarker of disease status. Neurology 2008 Apr 15;70(16 Pt 2):1411-7.
26. Gerhard A, Pavese N, Hotton G, Turkheimer F, Es M, Hammers A, et al. In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease. Neurobiol Dis 2006 Feb;21(2):404-12.
27. Ouchi Y, Yoshikawa E, Sekine Y, Futatsubashi M, Kanno T, Ogusu T, et al. Microglial activation and dopamine terminal loss in early Parkinson's disease. Ann Neurol 2005 Feb;57(2):168-75.
28. Miyoshi M, Shinotoh H, Wszolek ZK, Strongosky AJ, Shimada H, Arakawa R, et al. In vivo detection of neuropathologic changes in presymptomatic MAPT mutation carriers: a PET and MRI study. Parkinsonism Relat Disord 2010 Jul;16(6):404-8.
29. Bohnen NI, Muller ML, Koeppe RA, Studenski SA, Kilbourn MA, Frey KA, et al. History of falls in Parkinson disease is associated with reduced cholinergic activity. Neurology 2009 Nov 17;73(20):1670-6.
30. MaetzlerW, Liepelt I, Reimold M, Reischl G, Solbach C, Becker C, et al. Cortical PIB binding in Lewy body disease is associated with Alzheimer-like characteristics. Neurobiol Dis 2009 Apr;34(1):107-12.
31. Jokinen P, Scheinin N, Aalto S, Nagren K, Savisto N, Parkkola R, et al. [(11)C]PIB-, [(18)F]FDG-PET and MRI imaging in patients with Parkinson's disease with and without dementia. Parkinsonism Relat Disord 2010 Dec;16(10):666-70.
32. Claassen DO, Lowe VJ, Peller PJ, Petersen RC, Josephs KA. Amyloid and glucose imaging in dementia with Lewy bodies and multiple systems atrophy. Parkinsonism Relat Disord 2011 Mar;17(3):160-5.