Simulations of the p97 complex suggest novel conformational states of hydrolysis intermediates

Protein Science

Volumn 21, Issue 4, 2012, Pages 475-486

  Wereszczynski, Jeff ^a   McCammon, J Andrew ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b San Diego   (United States)

Author keywords

Molecular dynamics; Molecular dynamics flexible fitting; p97; Small angle X ray scattering

Indexed keywords

AMINO ACID; FLUORINE; FLUOROCARBON; GLUCAGON LIKE PEPTIDE 1; HEXAFLUORO 2 PROPANOL; HYDROCARBON; LEUCINE; PEXIGANAN; PROTEGRIN; TRIFLUOROETHANOL; VILLIN;

ALPHA HELIX; ARTICLE; BACTERIAL STRAIN; BETA SHEET; BIOLOGICAL ACTIVITY; COILED BODY; DIFFERENTIAL SCANNING CALORIMETRY; FLUORINATION; HYDROPHOBICITY; IN VIVO STUDY; KLEBSIELLA PNEUMONIAE; LIGAND BINDING; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DENATURATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN SYNTHESIS; SOLID PHASE SYNTHESIS; STAPHYLOCOCCUS AUREUS;

ADENOSINE TRIPHOSPHATASES; ALGORITHMS; HYDROLYSIS; MOLECULAR DYNAMICS SIMULATION; MULTIPROTEIN COMPLEXES; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SCATTERING, SMALL ANGLE; STRUCTURE-ACTIVITY RELATIONSHIP; X-RAY DIFFRACTION;

EID: 84858658517     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.2024     Document Type: Article

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