5-lipoxygenase deficiency impairs innate and adaptive immune responses during fungal infection

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Secatto, Adriana ^a   Rodrigues, Lilian Cataldi ^a   Serezani, Carlos Henrique ^b   Ramos, Simone Gusmão ^a   Dias Baruffi, Marcelo ^a   Faccioli, Lúcia Helena ^a   Medeiros, Alexandra I ^c  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; HERMES ANTIGEN; IMMUNOGLOBULIN G; LEUKOTRIENE B4; LEUKOTRIENE C4; NITRIC OXIDE; PADGEM PROTEIN;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; COLONY FORMING UNIT; CONTROLLED STUDY; EFFECTOR CELL; ENZYME DEFICIENCY; HISTOPLASMA CAPSULATUM; HISTOPLASMOSIS; HOST RESISTANCE; IN VITRO STUDY; IN VIVO STUDY; INFECTION SENSITIVITY; INNATE IMMUNITY; LUNG; MACROPHAGE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHAGOCYTOSIS; ANIMAL; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; CYTOTOXICITY; FLOW CYTOMETRY; HISTOPLASMA; HUMORAL IMMUNITY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MICROBIOLOGY; MORTALITY; MOUSE MUTANT; PERITONEUM MACROPHAGE; PHYSIOLOGY; SURVIVAL RATE; T LYMPHOCYTE;

AJELLOMYCES CAPSULATUS; MUS;

ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; CELL PROLIFERATION; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; FLOW CYTOMETRY; HISTOPLASMA; HISTOPLASMOSIS; IMMUNITY, HUMORAL; IMMUNITY, INNATE; LEUKOTRIENE B4; LEUKOTRIENE C4; LUNG; LYMPHOCYTE ACTIVATION; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; NITRIC OXIDE; PHAGOCYTOSIS; SURVIVAL RATE; T-LYMPHOCYTES;

EID: 84858637961     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031701     Document Type: Article

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