Spontaneous firing in C-fibers and increased mechanical sensitivity in A-fibers of knee joint-associated mechanoreceptive primary afferent neurones during MIA-induced osteoarthritis in the rat

Osteoarthritis and Cartilage

Volumn 20, Issue 4, 2012, Pages 305-313

  Kelly, S ^a,c   Dunham, J P ^a   Murray, F ^b   Read, S ^b   Donaldson, L F ^a   Lawson, S N ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Mechanical sensitivity; Mechanonociceptor; Osteoarthritis pain; Rat; Spontaneous firing; Spontaneous pain

Indexed keywords

IODOACETIC ACID; MONOSODIUM IODOACETATE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRALGIA; ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; INNERVATION; MALE; MECHANICAL STIMULATION; MECHANORECEPTOR; NERVE CONDUCTION; NOCICEPTION; NONHUMAN; OSTEOARTHRITIS; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; SENSORY NERVE; SENSORY NERVE CONDUCTION; WEIGHT BEARING;

ANIMALS; ARTHRITIS, EXPERIMENTAL; IODOACETATES; JOINTS; MALE; MECHANORECEPTORS; MECHANOTRANSDUCTION, CELLULAR; NERVE FIBERS, MYELINATED; NERVE FIBERS, UNMYELINATED; NEURAL CONDUCTION; NEURONS, AFFERENT; OSTEOARTHRITIS; PAIN; RATS; RATS, WISTAR; WEIGHT-BEARING;

EID: 84858618459     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2012.01.002     Document Type: Article

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