Dendritic carrier based on PEG: Design and degradation of acid-sensitive dendrimer-like poly(ethylene oxide)s

Macromolecular Rapid Communications

Volumn 32, Issue 21, 2011, Pages 1722-1728

  Feng, Xiaoshuang ^a,b   Chaikof, Elliot L ^c   Absalon, Christelle ^b   Drummond, Carlos ^d   Taton, Daniel ^a,b   Gnanou, Yves ^a,b  

^a UNIVERSITÉ BORDEAUX 1   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c HARVARD MEDICAL SCHOOL   (United States)

^d CENTRE DE RECHERCHE PAUL PASCAL   (France)

Author keywords

biodegradable; branching; dendrimer; ketal; poly(ethylene oxide)

Indexed keywords

AMPHIPHILES; ANIONIC POLYMERIZATION; CHAINS; DENDRIMERS; ETHYLENE; MASS SPECTROMETRY; POLYETHYLENE OXIDES; SCAFFOLDS;

ANIONIC RING OPENING POLYMERIZATION; BIODEGRADABLE; BRANCHING; CHEMICAL DEGRADATION; DIVERGENT APPROACH; KETAL; MALDI-TOF MASS SPECTROMETRY; PERIPHERAL HYDROXYL;

RING OPENING POLYMERIZATION;

DENDRIMER; DRUG CARRIER; MACROGOL DERIVATIVE;

ARTICLE; CHEMISTRY; DRUG DELIVERY SYSTEM; INSTRUMENTATION; MOLECULAR WEIGHT; SYNTHESIS;

DENDRIMERS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS;

EID: 84858613392     PISSN: 10221336     EISSN: 15213927     Source Type: Journal    
DOI: 10.1002/marc.201100459     Document Type: Article

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58. (n-1)). Here, nâ¥2; I(3.5) and I(0.9) are the integral intensity of the peaks appearing at around 3.5 and 0.9 ppm, respectively; 337 is the molar mass of branching points. For the sake of simplicity, we omitted the contribution from the nine protons arising from each branching points and did not subtract the corresponding intensity from the peak appearing at around 3.5 ppm.