Cytotoxicity and antioxidant activity of 23 plant species of Leguminosae family

Iranian Journal of Pharmaceutical Research

Volumn 11, Issue 1, 2012, Pages 295-302

  Khalighi Sigaroodi, Farahnaz ^a   Ahvazi, Maryam ^a   Hadjiakhoondi, Abbas ^b   Taghizadeh, Mitra ^a   Yazdani, Darab ^a   Khalighi Sigaroodi, Shahram ^c   Bidel, Siamak ^d,e  

^a AVICENNA RESEARCH INSTITUTE   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c UNIVERSITY OF TEHRAN   (Iran)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^e UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Antioxidant; Cytotoxicity; Leguminosae; Taverniera spartea

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ANTIOXIDANT; ASTRAGALUS SQUARROSUS EXTRACT; CAESALPINIA GILLIESII EXTRACT; CROTALARIA BURHIA EXTRACT; CYTOTOXIC AGENT; GLEDITSCHIA CASPICA EXTRACT; GLYCYRRHIZA GLABRA EXTRACT; INDIGOFERA ARTICULATA EXTRACT; INDIGOFERA INTRICATA EXTRACT; LATHYRUS ANNUS EXTRACT; LATHYRUS SATIVUS EXTRACT; LOTUS CORNICULATUS EXTRACT; MEDICAGO RIGIDULA EXTRACT; MELILOTUS INDICUS EXTRACT; ONOBRYCHIS ALTISSIMA EXTRACT; PLANT EXTRACT; SOPHORA ALOPECUROIDES EXTRACT; SOPHORA PACHYCARPA EXTRACT; TAVERNIERA CUNEIFOLIA EXTRACT; TAVERNIERA SPARTEA EXTRACT; TEPHROSIA PERSICA EXTRACT; THYMOL; TRIFOLIUM CAMPESTRE EXTRACT; TRIFOLIUM REPENS EXTRACT; TRIGONELLA SPRUNERIANA EXTRACT; UNCLASSIFIED DRUG; VICIA PEREGRINA EXTRACT;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTEMIA; ARTICLE; ASTRAGALUS SQUARROSUS; CAESALPINIA GILLIESII; CONTROLLED STUDY; CROTALARIA BURHIA; CYTOTOXICITY; CYTOTOXICITY TEST; DRUG CYTOTOXICITY; DRUG SCREENING; GLEDITSCHIA CASPICA; GLYCYRRHIZA GLABRA; IC 50; INDIGOFERA ARTICULATA; INDIGOFERA INTRICATA; LATHYRUS ANNUS; LATHYRUS SATIVUS; LC 50; LEGUME; LETHALITY; LOTUS CORNICULATUS; MEDICAGO RIGIDULA; MELILOTUS INDICUS; NONHUMAN; ONOBRYCHIS ALTISSIMA; SOPHORA ALOPECUROIDES; SOPHORA PACHYCARPA; TAVERNIERA CUNEIFOLIA; TAVERNIERA SPARTEA; TEPHROSIA PERSICA; TRIFOLIUM CAMPESTRE; TRIGONELLA SPRUNERIANA; VICIA PEREGRINA; WHITE CLOVER;

EID: 84858590738     PISSN: 17350328     EISSN: 17266890     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Jayaprakasha GK, Negi PS, Jena BS and Jagan Mohan Rao L. Antioxidant and antimutagenic activities of Cinnamomum zeylanicum fruit extracts. J. Food Compost. Anal. (2007) 20: 330-336.
2. Souri E, Amin G, Dehmobed-Sharifabadi A, Nazifi A and Farsam H. Antioxidative activity of sixty plants from Iran. Iranian J. Pharm. Res. (2004) 3: 55-59.
3. Costa-Lotufo LV, Hassan Khan MT, Ather A, Wilke DV, Jimenez PC, Pessoa C, de Moraes MEA and de Moraes MO. Studies of the anticancer potential of plants used in Bangladeshi folk medicine. J. Ethnopharmacol. (2005) 99: 21-30.
4. Quignard ELJ, Pohlit AM, Nunomura SM, Pinto ACS, dos Santos EVM, de Morais SKR, Alecrim AM, Pedroso ACS, Cyrino BRB, de Melo CS, Finney EK, Gomez EO, Souza KS, de Oliveira LCP, Don LC, e Silva LFR, Queiroz MMA, Henrique MC, dos Santos M, Pinto PS and Silva SG. Screening of plants found in Amazonas state for lethality towards brine shrimp. Acta Amazon. (2003) 33: 93-104.
5. Sokmen A. Antiviral and cytotoxic activities of extracts from the cell cultures and respective parts of some turkish medicinal plants. Turk. J. Biol. (2001) 25: 343-350.
6. Wanyoike GN, Chhabra SC, Lang'at-Thoruwa CC and Omarb SA. Brine shrimp toxicity and antiplasmodial activity of five Kenyan medicinal plants. J. Ethnopharmacol. (2004) 90(1): 129-133.
7. Meyer BN, Ferrigni NR, Putnam JE, Jacobsen LB, Nichols DE and McLaughlin JL. Brine shrimp: A convenient general bioassay for active plant constituents. Planta Med. (1982) 45: 31-34.
8. Awal MA, Nahar A, Hossain MS, Bari MA, Rahman M and Haque ME. Brine shrimp toxicity of leaf and seed extracts of Cassia alata Linn. and their antibacterial potency. J. Med. Sci. (2004) 4: 188-193.
9. Alves TMA, Silva AF, Brandao M, Grandi TSM, Samina EFA, Junior AS and Zani CL. Biological screening of Brazilian plants. Mem. Inst. Oswaldo Cruz (2000) 95: 367-373.
10. de Luna JS, dos Santos AF, de Lima MRF, de Omena MC, de Mendonca FAC, Bieber LW and Sant'Ana AEG. A study of the larvicidal and molluscicidal activities of some medicinal plants from northeast Brazil. J. Ethnopharmacol. (2005) 97: 199-206.
11. Rasoanaivo P and Ratsimamanga-Urverg S. Biological Evaluation of Plants with Reference to the Malagasy Flora. Napreca, Madagascar (1993) 9-83.
12. Afolayan AJ, Jimoh FO, Sofidiya MO, Koduru S and Lewu FB. Medicinal potential of the root of Arctotis arctotoides. Pharm. Biol. (2007) 45: 486-493.
13. Han J, Weng X and Bi K. Antioxidants from a Chinese medicinal herb-Lithospermum erythrorhizon. Food Chem. (2008) 106: 2-10.
14. Coruh N, Sagdicoglu Celep AG and Ozgokce F. Antioxidant properties of Prangos ferulacea (L.) Lindl., Chaerophyllum macropodum Boiss. and Heracleum persicum Desf. from Apiaceae family used as food in Eastern Anatolia and their inhibitory effects on glutathione-S-transferase. Food Chem. (2007) 100: 1237-1242.
15. Mothana RAA, Abdo SAA, Hasson S, Althawab FMN, Alaghbari SAZ and Lindequist U. Antimicrobial, antioxidant and cytotoxic activities and phytochemical screening of some Yemeni medicinal plants. eCAM (2010) 7: 323-330.
16. Ahmed Y, Sohrab MH, Al-Reza SM, Tareq FS, Hasan CM and Sattar MA. Antimicrobial and cytotoxic constituents from leaves of Sapium baccatum. Food Chem. Toxicol. (2010) 48: 549-552.
17. Saei-Dehkordi SS, Tajik H, Moradi M and Khalighi-Sigaroodi F. Chemical composition of essential oils in Zataria multiflora Boiss. from different parts of Iran and their radical scavenging and antimicrobial activity. Food Chem. Toxicol. (2010) 48: 1562-1567.
18. Moshafi MH, Sharififar F, Dehghan GR and Ameri A. Bioassay screening of the essential oil and various extracts of fruits of Heracleum persicum Desf. and rhizomes of Zingiber officinale Rosc. using brine shrimp cytotoxicity assay. Iranian J. Pharm. Res. (2009) 8: 59-63.
19. Middleton P, Stewart F, Al-Qahtani S, Egan P, O'Rourke C, Abdulrahman A, Byres M, Middleton M, Kumarasamy Y, Shoeb M, Nahar L, Delazar A and Sarker SD. Antioxidant, antibacterial activities and general toxicity of Alnus glutinosa, Fraxinus excelsior and Papaver rhoeas. Iranian J. Pharm. Res. (2005) 2: 81-86.
20. Suffness M and Pezzuto JM. Assays related to cancer drug discovery. In: Hostettmann K. (ed.) Methods in Plant Biochemistry: Assays for Bioactivity. Vol. 6. Academic Press, London (1990) 71-133.