Small molecule activation of lecithin cholesterol acyltransferase modulates lipoprotein metabolism in mice and hamsters

Metabolism: Clinical and Experimental

Volumn 61, Issue 4, 2012, Pages 470-481

  Chen, Zhu ^a   Wang, Sheng Ping ^a   Krsmanovic, Mihajlo L ^a   Castro Perez, Jose ^a   Gagen, Karen ^a   Mendoza, Vivienne ^a   Rosa, Ray ^a   Shah, Vinit ^a   He, Timothy ^a   Stout, Steve J ^a   Geoghagen, Neil S ^a   Lee, Sang H ^a   McLaren, David G ^a   Wang, Liangsu ^a   Roddy, Thomas P ^a   Plump, Andrew S ^a   Hubbard, Brian K ^a   Sinz, Christopher J ^a   Johns, Douglas G ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; BILE ACID; CHOLESTEROL ESTER; COMPOUND A; ENZYME ACTIVATOR; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; EX VIVO STUDY; GALLBLADDER; IN VITRO STUDY; IN VIVO STUDY; LIPOPROTEIN BLOOD LEVEL; LIPOPROTEIN METABOLISM; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; PHARMACODYNAMICS; PRIORITY JOURNAL; SINGLE DRUG DOSE; SYRIAN HAMSTER;

ANIMALS; BILE ACIDS AND SALTS; CHOLESTEROL; CHOLESTEROL ESTERS; CRICETINAE; ENZYME ACTIVATION; FEMALE; LIPOPROTEINS; LIPOPROTEINS, HDL; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MESOCRICETUS; MICE; MICE, INBRED C57BL; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; THIADIAZOLES; TRIGLYCERIDES;

EID: 84858442462     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2011.08.006     Document Type: Article

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