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Volumn 109, Issue 7, 2012, Pages 968-985

Novel therapeutics for the management of castration-resistant prostate cancer (CRPC)

Author keywords

castration resistant prostate cancer; cytotoxic agents; docetaxel; first line therapy; prostate specific antigen; second line therapy

Indexed keywords

4 [3 [4 CYANO 3 (TRIFLUOROMETHYL)PHENYL] 5,5 DIMETHYL 4 OXO 2 THIOXO 1 IMIDAZOLIDINYL] 2 FLUORO N METHYLBENZAMIDE; ABIRATERONE; ANTINEOPLASTIC AGENT; BCL 2 INHIBITOR; BEVACIZUMAB; BIOLOGICAL MARKER; CABAZITAXEL; CALCITRIOL; CUSTIRSEN; CYTOTOXIC AGENT; DEXAMETHASONE; DOCETAXEL; ENDOTHELIN RECEPTOR ANTAGONIST; EPOTHILONE DERIVATIVE; ERIBULIN; ESTRAMUSTINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR VACCINE; IPILIMUMAB; MITOXANTRONE; OBLIMERSEN; PLACEBO; PREDNISONE; PROSTATE SPECIFIC ANTIGEN; PROSTATE SPECIFIC MEMBRANE ANTIGEN ANTIBODY; PROTEIN TYROSINE KINASE INHIBITOR; SIPULEUCEL T; THALIDOMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR INHIBITOR;

EID: 84858441614     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2011.10643.x     Document Type: Review
Times cited : (25)

References (110)
  • 2
    • 75249099988 scopus 로고    scopus 로고
    • Novel targeted therapies for prostate cancer
    • Macfarlane R, Chi K,. Novel targeted therapies for prostate cancer. Urol Clin North Am 2010; 37: 105-19
    • (2010) Urol Clin North Am , vol.37 , pp. 105-119
    • MacFarlane, R.1    Chi, K.2
  • 3
    • 61549086593 scopus 로고    scopus 로고
    • Screening for prostate cancer: An update
    • Shariat SF, Scardino PT, Lilja H,. Screening for prostate cancer: an update. Can J Urol 2008; 15: 4363-74
    • (2008) Can J Urol , vol.15 , pp. 4363-4374
    • Shariat, S.F.1    Scardino, P.T.2    Lilja, H.3
  • 5
    • 77949910429 scopus 로고    scopus 로고
    • Castrate-resistant prostate cancer: Therapeutic strategies
    • Harzstark A, Small E,. Castrate-resistant prostate cancer: therapeutic strategies. Expert Opin Pharmacother 2010; 11: 937-45
    • (2010) Expert Opin Pharmacother , vol.11 , pp. 937-945
    • Harzstark, A.1    Small, E.2
  • 6
    • 67650376190 scopus 로고    scopus 로고
    • Emerging therapies in castrate-resistant prostate cancer
    • Lassi K, Dawson N,. Emerging therapies in castrate-resistant prostate cancer. Curr Opin Oncol 2009; 21: 260-5
    • (2009) Curr Opin Oncol , vol.21 , pp. 260-265
    • Lassi, K.1    Dawson, N.2
  • 7
    • 12744251833 scopus 로고    scopus 로고
    • Beyond prostate-specific antigen: New serologic biomarkers for improved diagnosis and management of prostate cancer
    • Shariat SF, Canto EI, Kattan MW, Slawin KM,. Beyond prostate-specific antigen: new serologic biomarkers for improved diagnosis and management of prostate cancer. Rev Urol 2004; 6: 58-72
    • (2004) Rev Urol , vol.6 , pp. 58-72
    • Shariat, S.F.1    Canto, E.I.2    Kattan, M.W.3    Slawin, K.M.4
  • 8
    • 69449095278 scopus 로고    scopus 로고
    • Docetaxel down-regulates the expression of androgen receptor and prostate-specific antigen but not prostate-specific membrane antigen in prostate cancer cell lines: Implications for PSA surrogacy
    • Kuroda K, Liu H, Kim S, Guo M, Navarro V, Bander NH,. Docetaxel down-regulates the expression of androgen receptor and prostate-specific antigen but not prostate-specific membrane antigen in prostate cancer cell lines: implications for PSA surrogacy. Prostate 2009; 69: 1579-85
    • (2009) Prostate , vol.69 , pp. 1579-1585
    • Kuroda, K.1    Liu, H.2    Kim, S.3    Guo, M.4    Navarro, V.5    Bander, N.H.6
  • 9
    • 41949104346 scopus 로고    scopus 로고
    • Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group
    • Scher H, Halabi S, Tannock I, et al,. Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group. J Clin Oncol 2008; 26: 1148-59
    • (2008) J Clin Oncol , vol.26 , pp. 1148-1159
    • Scher, H.1    Halabi, S.2    Tannock, I.3
  • 10
    • 66349137641 scopus 로고    scopus 로고
    • Prostate-specific antigen progression predicts overall survival in patients with metastatic prostate cancer: Data from Southwest Oncology Group Trials 9346 (Intergroup Study 0162) and 9916
    • Hussain M, Goldman B, Tangen C, et al,. Prostate-specific antigen progression predicts overall survival in patients with metastatic prostate cancer: data from Southwest Oncology Group Trials 9346 (Intergroup Study 0162) and 9916. J Clin Oncol 2009; 27: 2450-6
    • (2009) J Clin Oncol , vol.27 , pp. 2450-2456
    • Hussain, M.1    Goldman, B.2    Tangen, C.3
  • 11
    • 0029888978 scopus 로고    scopus 로고
    • Suramin-induced decrease in prostate-specific antigen expression with no effect on tumor growth in the LNCaP model of human prostate cancer
    • DOI 10.1093/jnci/88.12.794
    • Thalmann GN, Sikes RA, Chang SM, Johnston DA, von Eschenbach AC, Chung LW,. Suramin-induced decrease in prostate-specific antigen expression with no effect on tumor growth in the LNCaP model of human prostate cancer. J Natl Cancer Inst 1996; 88: 794-801 (Pubitemid 26187388)
    • (1996) Journal of the National Cancer Institute , vol.88 , Issue.12 , pp. 794-801
    • Thalmann, G.N.1    Sikes, R.A.2    Chang, S.-M.3    Johnston, D.A.4    Von Eschenbach, A.C.5    Chung, L.W.K.6
  • 12
    • 0035101380 scopus 로고    scopus 로고
    • The control of prostate-specific antigen expression and gene regulation by pharmacological agents
    • Dixon SC, Knopf KB, Figg WD,. The control of prostate-specific antigen expression and gene regulation by pharmacological agents. Pharmacol Rev 2001; 53: 73-91 (Pubitemid 32173108)
    • (2001) Pharmacological Reviews , vol.53 , Issue.1 , pp. 73-91
    • Dixon, S.C.1    Knopf, K.B.2    Figg, W.D.3
  • 13
    • 33751558449 scopus 로고    scopus 로고
    • Post-therapy changes in PSA as an outcome measure in prostate cancer clinical trials
    • DOI 10.1038/ncponc0664, PII NCPONC0664
    • Fleming MT, Morris MJ, Heller G, Scher HI,. Post-therapy changes in PSA as an outcome measure in prostate cancer clinical trials. Nat Clin Pract Oncol 2006; 3: 658-67 (Pubitemid 44843124)
    • (2006) Nature Clinical Practice Oncology , vol.3 , Issue.12 , pp. 658-667
    • Fleming, M.T.1    Morris, M.J.2    Heller, G.3    Scher, H.I.4
  • 16
    • 77952105685 scopus 로고    scopus 로고
    • Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study
    • Scher H, Beer T, Higano C, et al,. Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study. Lancet 2010; 375: 1437-46
    • (2010) Lancet , vol.375 , pp. 1437-1446
    • Scher, H.1    Beer, T.2    Higano, C.3
  • 18
    • 58149165081 scopus 로고    scopus 로고
    • Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer
    • de Bono JS, Scher HI, Montgomery RB, et al,. Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer. Clin Cancer Res 2008; 14: 6302-9
    • (2008) Clin Cancer Res , vol.14 , pp. 6302-6309
    • De Bono, J.S.1    Scher, H.I.2    Montgomery, R.B.3
  • 19
    • 79551703389 scopus 로고    scopus 로고
    • Abiraterone acetate is well tolerated without concomitant use of corticosteroids
    • author reply e562
    • Attard G, Reid A, de Bono J,. Abiraterone acetate is well tolerated without concomitant use of corticosteroids. J Clin Oncol 2010; 28: e560-1; author reply e562
    • (2010) J Clin Oncol , vol.28
    • Attard, G.1    Reid, A.2    De Bono, J.3
  • 20
    • 77953015030 scopus 로고    scopus 로고
    • Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer
    • Stott S, Lee R, Nagrath S, et al,. Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer. Sci Transl Med 2010; 2: 25ra3
    • (2010) Sci Transl Med , vol.2
    • Stott, S.1    Lee, R.2    Nagrath, S.3
  • 21
    • 77951922478 scopus 로고    scopus 로고
    • Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody
    • Gleghorn J, Pratt E, Denning D, et al,. Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody. Lab Chip 2010; 10: 27-9
    • (2010) Lab Chip , vol.10 , pp. 27-29
    • Gleghorn, J.1    Pratt, E.2    Denning, D.3
  • 25
    • 77951644363 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab, thalidomide, docetaxel, and prednisone in patients with metastatic castration-resistant prostate cancer
    • Ning Y, Gulley J, Arlen P, et al,. Phase II trial of bevacizumab, thalidomide, docetaxel, and prednisone in patients with metastatic castration-resistant prostate cancer. J Clin Oncol 2010; 28: 2070-6
    • (2010) J Clin Oncol , vol.28 , pp. 2070-2076
    • Ning, Y.1    Gulley, J.2    Arlen, P.3
  • 27
    • 38049032293 scopus 로고    scopus 로고
    • Intermittent chemotherapy in patients with metastatic androgen-independent prostate cancer: Results from ASCENT, a double-blinded, randomized comparison of high-dose calcitriol plus docetaxel with placebo plus docetaxel
    • Beer TM, Ryan CW, Venner PM, et al,. Intermittent chemotherapy in patients with metastatic androgen-independent prostate cancer: results from ASCENT, a double-blinded, randomized comparison of high-dose calcitriol plus docetaxel with placebo plus docetaxel. Cancer 2008; 112: 326-30
    • (2008) Cancer , vol.112 , pp. 326-330
    • Beer, T.M.1    Ryan, C.W.2    Venner, P.M.3
  • 28
    • 79957953692 scopus 로고    scopus 로고
    • Randomized, Open-Label Phase III Trial of Docetaxel Plus High-Dose Calcitriol Versus Docetaxel Plus Prednisone for Patients with Castration-Resistant Prostate Cancer
    • Scher HI, Jia X, Chi K, et al,. Randomized, Open-Label Phase III Trial of Docetaxel Plus High-Dose Calcitriol Versus Docetaxel Plus Prednisone for Patients With Castration-Resistant Prostate Cancer. J Clin Oncol 2011; 29: 2191-8
    • (2011) J Clin Oncol , vol.29 , pp. 2191-2198
    • Scher, H.I.1    Jia, X.2    Chi, K.3
  • 30
    • 67650360358 scopus 로고    scopus 로고
    • Docetaxel plus oblimersen sodium (Bcl-2 antisense oligonucleotide): An EORTC multicenter, randomized phase II study in patients with castration-resistant prostate cancer
    • Sternberg C, Dumez H, Van Poppel H, et al,. Docetaxel plus oblimersen sodium (Bcl-2 antisense oligonucleotide): an EORTC multicenter, randomized phase II study in patients with castration-resistant prostate cancer. Ann Oncol 2009; 20: 1264-9
    • (2009) Ann Oncol , vol.20 , pp. 1264-1269
    • Sternberg, C.1    Dumez, H.2    Van Poppel, H.3
  • 31
    • 77957957234 scopus 로고    scopus 로고
    • Randomized phase II study of docetaxel and prednisone with or without OGX-011 in patients with metastatic castration-resistant prostate cancer
    • Chi KN, Hotte SJ, Yu EY, et al,. Randomized phase II study of docetaxel and prednisone with or without OGX-011 in patients with metastatic castration-resistant prostate cancer. J Clin Oncol 2010; 28: 4247-54
    • (2010) J Clin Oncol , vol.28 , pp. 4247-4254
    • Chi, K.N.1    Hotte, S.J.2    Yu, E.Y.3
  • 32
    • 79251516754 scopus 로고    scopus 로고
    • A phase 2 study of estramustine, docetaxel, and bevacizumab in men with castrate-resistant prostate cancer: Results from Cancer and Leukemia Group B Study 90006
    • Picus J, Halabi S, Kelly WK, et al,. A phase 2 study of estramustine, docetaxel, and bevacizumab in men with castrate-resistant prostate cancer: results from Cancer and Leukemia Group B Study 90006. Cancer 2011; 117: 526-33
    • (2011) Cancer , vol.117 , pp. 526-533
    • Picus, J.1    Halabi, S.2    Kelly, W.K.3
  • 33
    • 52049090425 scopus 로고    scopus 로고
    • Phase 1/2 dose-escalation study of a GM-CSF-secreting, allogeneic, cellular immunotherapy for metastatic hormone-refractory prostate cancer
    • Higano C, Corman J, Smith D, et al,. Phase 1/2 dose-escalation study of a GM-CSF-secreting, allogeneic, cellular immunotherapy for metastatic hormone-refractory prostate cancer. Cancer 2008; 113: 975-84
    • (2008) Cancer , vol.113 , pp. 975-984
    • Higano, C.1    Corman, J.2    Smith, D.3
  • 35
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • Kantoff PW, Higano CS, Shore ND, et al,. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010; 363: 411-22
    • (2010) N Engl J Med , vol.363 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3
  • 36
    • 68549135290 scopus 로고    scopus 로고
    • Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
    • Higano C, Schellhammer P, Small E, et al,. Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 2009; 115: 3670-9
    • (2009) Cancer , vol.115 , pp. 3670-3679
    • Higano, C.1    Schellhammer, P.2    Small, E.3
  • 38
    • 62649134676 scopus 로고    scopus 로고
    • Safety and efficacy of the specific endothelin-A receptor antagonist ZD4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: A double-blind, placebo-controlled, randomised, phase 2 trial
    • James N, Caty A, Borre M, et al,. Safety and efficacy of the specific endothelin-A receptor antagonist ZD4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: a double-blind, placebo-controlled, randomised, phase 2 trial. Eur Urol 2009; 55: 1112-23
    • (2009) Eur Urol , vol.55 , pp. 1112-1123
    • James, N.1    Caty, A.2    Borre, M.3
  • 39
    • 73149115110 scopus 로고    scopus 로고
    • Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer
    • Yu E, Wilding G, Posadas E, et al,. Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer. Clin Cancer Res 2009; 15: 7421-8
    • (2009) Clin Cancer Res , vol.15 , pp. 7421-7428
    • Yu, E.1    Wilding, G.2    Posadas, E.3
  • 40
    • 70249151654 scopus 로고    scopus 로고
    • Dasatinib and docetaxel combination treatment for patients with castration-resistant progressive prostate cancer: A phase I/II study (CA180086)
    • abstract 5061 (Meeting Abstracts)
    • Araujo J, Armstrong AJ, Braud EL, et al,. Dasatinib and docetaxel combination treatment for patients with castration-resistant progressive prostate cancer: a phase I/II study (CA180086). J Clin Oncol 2009; 27 (Suppl.): abstract 5061 (Meeting Abstracts)
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL.
    • Araujo, J.1    Armstrong, A.J.2    Braud, E.L.3
  • 41
    • 78649432083 scopus 로고    scopus 로고
    • 177Lu-J591) in patients (pts) with metastatic castrate-resistant prostate cancer (metCRPC)
    • 177Lu-J591) in patients (pts) with metastatic castrate-resistant prostate cancer (metCRPC). J Clin Oncol 2008; 26: 5140
    • (2008) J Clin Oncol , vol.26 , pp. 5140
    • Tagawa, S.T.1    Milowsky, M.I.2    Morris, M.J.3
  • 42
    • 77951523950 scopus 로고    scopus 로고
    • Phase i clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy
    • Ryan CJ, Smith MR, Fong L, et al,. Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy. J Clin Oncol 2010; 28: 1481-8
    • (2010) J Clin Oncol , vol.28 , pp. 1481-1488
    • Ryan, C.J.1    Smith, M.R.2    Fong, L.3
  • 43
    • 68949094223 scopus 로고    scopus 로고
    • Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer
    • Attard G, Reid AH, A'Hern R, et al,. Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J Clin Oncol 2009; 27: 3742-8
    • (2009) J Clin Oncol , vol.27 , pp. 3742-3748
    • Attard, G.1    Reid, A.H.2    A'Hern, R.3
  • 45
    • 0344236282 scopus 로고    scopus 로고
    • A Phase II Study of Estramustine, Docetaxel, and Carboplatin with Granulocyte-Colony-Stimulating Factor Support in Patients with Hormone-Refractory Prostate Carcinoma: Cancer and Leukemia Group B 99813
    • DOI 10.1002/cncr.11829
    • Oh W, Halabi S, Kelly W, et al,. A phase II study of estramustine, docetaxel, and carboplatin with granulocyte-colony-stimulating factor support in patients with hormone-refractory prostate carcinoma: cancer and Leukemia Group B 99813. Cancer 2003; 98: 2592-8 (Pubitemid 37509522)
    • (2003) Cancer , vol.98 , Issue.12 , pp. 2592-2598
    • Oh, W.K.1    Halabi, S.2    Kelly, W.K.3    Werner, C.4    Godley, P.A.5    Vogelzang, N.J.6    Small, E.J.7
  • 46
    • 33846515135 scopus 로고    scopus 로고
    • Weekly Docetaxel and Epirubicin in Treatment of Advanced Hormone-Refractory Prostate Cancer
    • DOI 10.1016/j.urology.2006.09.015, PII S0090429506021376
    • Petrioli R, Paolelli L, Francini E, Manganelli A, Salvestrini F, Francini G,. Weekly docetaxel and epirubicin in treatment of advanced hormone-refractory prostate cancer. Urology 2007; 69: 142-6 (Pubitemid 46161681)
    • (2007) Urology , vol.69 , Issue.1 , pp. 142-146
    • Petrioli, R.1    Paolelli, L.2    Francini, E.3    Manganelli, A.4    Salvestrini, F.5    Francini, G.6
  • 47
    • 77951877997 scopus 로고    scopus 로고
    • A phase i clinical study of high dose ketoconazole plus weekly docetaxel for metastatic castration resistant prostate cancer
    • Figg WD, Woo S, Zhu W, et al,. A phase I clinical study of high dose ketoconazole plus weekly docetaxel for metastatic castration resistant prostate cancer. J Urol 2010; 183: 2219-26
    • (2010) J Urol , vol.183 , pp. 2219-2226
    • Figg, W.D.1    Woo, S.2    Zhu, W.3
  • 48
    • 77749280814 scopus 로고    scopus 로고
    • A phase i open-label study using lenalidomide and docetaxel in castration-resistant prostate cancer
    • (abstract 5156)
    • Petrylak DP, Resto-Garces K, Tibyan M, Mohile SG,. A phase I open-label study using lenalidomide and docetaxel in castration-resistant prostate cancer. J Clin Oncol 2009; 27 (Suppl.): 272s (abstract 5156)
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL.
    • Petrylak, D.P.1    Resto-Garces, K.2    Tibyan, M.3    Mohile, S.G.4
  • 49
    • 0028168202 scopus 로고
    • Human prostate cancer cells: Inhibition of proliferation by vitamin D analogs
    • Schwartz G, Oeler T, UskokoviÄ M, Bahnson R,. Human prostate cancer cells: inhibition of proliferation by vitamin D analogs. Anticancer Res 1994; 14: 1077-81 (Pubitemid 24272570)
    • (1994) Anticancer Research , vol.14 , Issue.3 , pp. 1077-1081
    • Schwartz, G.G.1    Oeler, T.A.2    Uskokovic, M.R.3    Bahnson, R.R.4
  • 50
    • 26944445883 scopus 로고    scopus 로고
    • Clusterin inhibits apoptosis by interacting with activated Bax
    • DOI 10.1038/ncb1291, PII N1291
    • Zhang H, Kim JK, Edwards CA, Xu Z, Taichman R, Wang CY,. Clusterin inhibits apoptosis by interacting with activated Bax. Nat Cell Biol 2005; 7: 909-15 (Pubitemid 41486292)
    • (2005) Nature Cell Biology , vol.7 , Issue.9 , pp. 909-915
    • Zhang, H.1    Kim, J.K.2    Edwards, C.A.3    Xu, Z.4    Taichman, R.5    Wang, C.-Y.6
  • 51
    • 0034719136 scopus 로고    scopus 로고
    • Clusterin is an ATP - Independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state
    • DOI 10.1021/bi002189x
    • Poon S, Easterbrook-Smith SB, Rybchyn MS, Carver JA, Wilson MR,. Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state. Biochemistry 2000; 39: 15953-60 (Pubitemid 32038257)
    • (2000) Biochemistry , vol.39 , Issue.51 , pp. 15953-15960
    • Poon, S.1    Easterbrook-Smith, S.B.2    Rybchyn, M.S.3    Carver, J.A.4    Wilson, M.R.5
  • 52
    • 75149124457 scopus 로고    scopus 로고
    • Clusterin facilitates COMMD1 and I-kappaB degradation to enhance NF-kappaB activity in prostate cancer cells
    • Zoubeidi A, Ettinger S, Beraldi E, et al,. Clusterin facilitates COMMD1 and I-kappaB degradation to enhance NF-kappaB activity in prostate cancer cells. Mol Cancer Res 2010; 8: 119-30
    • (2010) Mol Cancer Res , vol.8 , pp. 119-130
    • Zoubeidi, A.1    Ettinger, S.2    Beraldi, E.3
  • 53
    • 0037083472 scopus 로고    scopus 로고
    • Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy
    • DOI 10.1002/pros.10047
    • July LV, Akbari M, Zellweger T, Jones EC, Goldenberg SL, Gleave ME,. Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy. Prostate 2002; 50: 179-88 (Pubitemid 34137445)
    • (2002) Prostate , vol.50 , Issue.3 , pp. 179-188
    • July, L.V.1    Akbari, M.2    Zellweger, T.3    Jones, E.C.4    Goldenberg, S.L.5    Gleave, M.E.6
  • 54
    • 0033978525 scopus 로고    scopus 로고
    • Testosterone-repressed prostate message-2 is an antiapoptotic gene involved in progression to androgen independence in prostate cancer
    • Miyake H, Nelson C, Rennie PS, Gleave ME,. Testosterone-repressed prostate message-2 is an antiapoptotic gene involved in progression to androgen independence in prostate cancer. Cancer Res 2000; 60: 170-6 (Pubitemid 30058748)
    • (2000) Cancer Research , vol.60 , Issue.1 , pp. 170-176
    • Miyake, H.1    Nelson, C.2    Rennie, P.S.3    Gleave, M.E.4
  • 55
    • 0034772250 scopus 로고    scopus 로고
    • Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480
    • George D, Halabi S, Shepard T, et al,. Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480. Clin Cancer Res 2001; 7: 1932-6 (Pubitemid 32994827)
    • (2001) Clinical Cancer Research , vol.7 , Issue.7 , pp. 1932-1936
    • George, D.J.1    Halabi, S.2    Shepard, T.F.3    Vogelzang, N.J.4    Hayes, D.F.5    Small, E.J.6    Kantoff, P.W.7
  • 56
    • 2442641793 scopus 로고    scopus 로고
    • Association of preoperative plasma levels of vascular endothelial growth factor and soluble vascular cell adhesion molecule-1 with lymph node status and biochemical progression after radical prostatectomy
    • DOI 10.1200/JCO.2004.09.142
    • Shariat S, Anwuri V, Lamb D, Shah N, Wheeler T, Slawin K,. Association of preoperative plasma levels of vascular endothelial growth factor and soluble vascular cell adhesion molecule-1 with lymph node status and biochemical progression after radical prostatectomy. J Clin Oncol 2004; 22: 1655-63 (Pubitemid 41079804)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.9 , pp. 1655-1663
    • Shariat, S.F.1    Anwuri, V.A.2    Lamb, D.J.3    Shah, N.V.4    Wheeler, T.M.5    Slawin, K.M.6
  • 57
    • 77955714649 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled phase III trial comparing docetaxel, prednisone, and placebo with docetaxel, prednisone, and bevacizumab in men with metastatic castration-resistant prostate cancer (mCRPC): Survival results of CALGB 90401
    • Kelly W, Halabi S, Carducci D, et al,. A randomized, double-blind, placebo-controlled phase III trial comparing docetaxel, prednisone, and placebo with docetaxel, prednisone, and bevacizumab in men with metastatic castration-resistant prostate cancer (mCRPC): survival results of CALGB 90401. J Clin Oncol 2010; 28: 18s
    • (2010) J Clin Oncol , vol.28
    • Kelly, W.1    Halabi, S.2    Carducci, D.3
  • 59
    • 79959869773 scopus 로고    scopus 로고
    • Epothilones in prostate cancer
    • Kelly W,. Epothilones in prostate cancer. Urol Oncol 2011; 29: 358-65
    • (2011) Urol Oncol , vol.29 , pp. 358-365
    • Kelly, W.1
  • 62
    • 71249133336 scopus 로고    scopus 로고
    • Phase II study of first-line sagopilone combined with prednisone in patients with metastatic castration-resistant prostate cancer (CRPC)
    • abstract 5059 (Meeting Abstracts)
    • Beer TM, Smith DC, Hussain A, et al,. Phase II study of first-line sagopilone combined with prednisone in patients with metastatic castration-resistant prostate cancer (CRPC). J Clin Oncol 2009; 27 (Suppl.): abstract 5059 (Meeting Abstracts)
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL.
    • Beer, T.M.1    Smith, D.C.2    Hussain, A.3
  • 63
    • 58749099507 scopus 로고    scopus 로고
    • Phase II study of sagopilone (ZK-EPO) plus prednisone as first-line chemotherapy in patients with metastatic androgen-independent prostate cancer (AIPC)
    • abstract 5141
    • Graff J, Smith DC, Neerukonda L, et al,. Phase II study of sagopilone (ZK-EPO) plus prednisone as first-line chemotherapy in patients with metastatic androgen-independent prostate cancer (AIPC). J Clin Oncol 2008; 26 (Suppl.): abstract 5141
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Graff, J.1    Smith, D.C.2    Neerukonda, L.3
  • 64
    • 79959285684 scopus 로고    scopus 로고
    • Phase II study of eribulin mesylate (E7389) in patients with metastatic castration-resistant prostate cancer (CRPC) stratified by prior taxane therapy
    • de Bono JS, Maroto P, Calvo E, et al,. Phase II study of eribulin mesylate (E7389) in patients with metastatic castration-resistant prostate cancer (CRPC) stratified by prior taxane therapy. Genitourinary Cancer Symposium 2009. Available at
    • (2009) Genitourinary Cancer Symposium
    • De Bono, J.S.1    Maroto, P.2    Calvo, E.3
  • 65
    • 70349926513 scopus 로고    scopus 로고
    • A phase III trial of GVAX immunotherapy for prostate cancer in combination with docetaxel versus docetaxel plus prednisone in symptomatic, castration-resistant prostate cancer
    • Small E, Demkow T, Gerritsen WR, et al,. A phase III trial of GVAX immunotherapy for prostate cancer in combination with docetaxel versus docetaxel plus prednisone in symptomatic, castration-resistant prostate cancer. Genitourinary Cancer Symposium 2009. Available at
    • (2009) Genitourinary Cancer Symposium
    • Small, E.1    Demkow, T.2    Gerritsen, W.R.3
  • 66
    • 71249156207 scopus 로고    scopus 로고
    • A phase III trial of GVAX immunotherapy for prostate cancer versus docetaxel plus prednisone in asymptomatic, castration-resistant prostate cancer
    • Higano C, Saad F, Somer B, et al,. A phase III trial of GVAX immunotherapy for prostate cancer versus docetaxel plus prednisone in asymptomatic, castration-resistant prostate cancer. Genitourinary Cancer Symposium 2009. Available at
    • (2009) Genitourinary Cancer Symposium
    • Higano, C.1    Saad, F.2    Somer, B.3
  • 67
    • 66249105438 scopus 로고    scopus 로고
    • Phase i trial of ipilimumab (IPI) alone and in combination with radiotherapy (XRT) in patients with metastatic castration resistant prostate cancer (mCRPC)
    • abstr 5004
    • Beer TM, Slovin SF, Higano CS, et al,. Phase I trial of ipilimumab (IPI) alone and in combination with radiotherapy (XRT) in patients with metastatic castration resistant prostate cancer (mCRPC). J Clin Oncol 2008; 26 (Suppl.): abstr 5004
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Beer, T.M.1    Slovin, S.F.2    Higano, C.S.3
  • 68
    • 58349090027 scopus 로고    scopus 로고
    • Potentiating endogenous antitumor immunity to prostate cancer through combination immunotherapy with CTLA4 blockade and GM-CSF
    • Fong L, Kwek SS, O'Brien S, et al,. Potentiating endogenous antitumor immunity to prostate cancer through combination immunotherapy with CTLA4 blockade and GM-CSF. Cancer Res 2009; 69: 609-15
    • (2009) Cancer Res , vol.69 , pp. 609-615
    • Fong, L.1    Kwek, S.S.2    O'Brien, S.3
  • 69
    • 0029085123 scopus 로고
    • Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate
    • Nelson J, Hedican S, George D, et al,. Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat Med 1995; 1: 944-9
    • (1995) Nat Med , vol.1 , pp. 944-949
    • Nelson, J.1    Hedican, S.2    George, D.3
  • 71
    • 51049106854 scopus 로고    scopus 로고
    • Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa
    • Meng Y, Tang W, Dai Y, et al,. Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa. Mol Cancer Ther 2008; 7: 2192-202
    • (2008) Mol Cancer Ther , vol.7 , pp. 2192-2202
    • Meng, Y.1    Tang, W.2    Dai, Y.3
  • 72
    • 65649130832 scopus 로고    scopus 로고
    • An open-label, multicenter, phase I/II study of single-agent AT-101 in men with castrate-resistant prostate cancer
    • Liu G, Kelly WK, Wilding G, Leopold L, Brill K, Somer B,. An open-label, multicenter, phase I/II study of single-agent AT-101 in men with castrate-resistant prostate cancer. Clin Cancer Res 2009; 15: 3172-6
    • (2009) Clin Cancer Res , vol.15 , pp. 3172-3176
    • Liu, G.1    Kelly, W.K.2    Wilding, G.3    Leopold, L.4    Brill, K.5    Somer, B.6
  • 73
    • 77951887506 scopus 로고    scopus 로고
    • Sunitinib malate for metastatic castration-resistant prostate cancer following docetaxel-based chemotherapy
    • Sonpavde G, Periman PO, Bernold D, et al,. Sunitinib malate for metastatic castration-resistant prostate cancer following docetaxel-based chemotherapy. Ann Oncol 2010; 21: 319-24
    • (2010) Ann Oncol , vol.21 , pp. 319-324
    • Sonpavde, G.1    Periman, P.O.2    Bernold, D.3
  • 74
    • 77952223624 scopus 로고    scopus 로고
    • Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors
    • Olsson A, Bjork A, Vallon-Christersson J, Isaacs JT, Leanderson T,. Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors. Mol Cancer 2010; 9: 107
    • (2010) Mol Cancer , vol.9 , pp. 107
    • Olsson, A.1    Bjork, A.2    Vallon-Christersson, J.3    Isaacs, J.T.4    Leanderson, T.5
  • 76
    • 0032104284 scopus 로고    scopus 로고
    • Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma: A study of 184 cases
    • DOI 10.1002/(SICI)1097-0142(19980601)82:11<2256::AID-CNCR22>3.0. CO;2-S
    • Bostwick D, Pacelli A, Blute M, Roche P, Murphy G,. Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma: a study of 184 cases. Cancer 1998; 82: 2256-61 (Pubitemid 28240834)
    • (1998) Cancer , vol.82 , Issue.11 , pp. 2256-2261
    • Bostwick, D.G.1    Pacelli, A.2    Blute, M.3    Roche, P.4    Murphy, G.P.5
  • 77
    • 4344618391 scopus 로고    scopus 로고
    • Phase I trial of yttrium-90-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for androgen-independent prostate cancer
    • DOI 10.1200/JCO.2004.09.154
    • Milowsky M, Nanus D, Kostakoglu L, Vallabhajosula S, Goldsmith S, Bander N,. Phase I trial of yttrium-90-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for androgen-independent prostate cancer. J Clin Oncol 2004; 22: 2522-31 (Pubitemid 41103739)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.13 , pp. 2522-2531
    • Milowsky, M.I.1    Nanus, D.M.2    Kostakoglu, L.3    Vallabhajosula, S.4    Goldsmith, S.J.5    Bander, N.H.6
  • 79
    • 22044451179 scopus 로고    scopus 로고
    • 177Lutetium-labeled J591, a monoclonal antibody to prostate-specific membrane antigen, in patients with androgen-independent prostate cancer
    • DOI 10.1200/JCO.2005.05.160
    • Bander N, Milowsky M, Nanus D, Kostakoglu L, Vallabhajosula S, Goldsmith S,. Phase I trial of 177lutetium-labeled J591, a monoclonal antibody to prostate-specific membrane antigen, in patients with androgen-independent prostate cancer. J Clin Oncol 2005; 23: 4591-601 (Pubitemid 46224061)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.21 , pp. 4591-4601
    • Bander, N.H.1    Milowsky, M.I.2    Nanus, D.M.3    Kostakoglu, L.4    Vallabhajosula, S.5    Goldsmith, S.J.6
  • 80
    • 79956201428 scopus 로고    scopus 로고
    • 177Lu-J591) in patients (pts) with metastatic castration-resistant prostate cancer (metCRPC)
    • 177Lu-J591) in patients (pts) with metastatic castration-resistant prostate cancer (metCRPC). J Clin Oncol 2010; 28: 4667
    • (2010) J Clin Oncol , vol.28 , pp. 4667
    • Tagawa, S.T.1    Vallabahajosula, S.2    Osborne, J.3
  • 81
    • 76349109469 scopus 로고    scopus 로고
    • Anti-prostate-specific membrane antigen-based radioimmunotherapy for prostate cancer
    • Tagawa ST, Beltran H, Vallabhajosula S, et al,. Anti-prostate-specific membrane antigen-based radioimmunotherapy for prostate cancer. Cancer 2010; 116: 1075-83
    • (2010) Cancer , vol.116 , pp. 1075-1083
    • Tagawa, S.T.1    Beltran, H.2    Vallabhajosula, S.3
  • 82
    • 84858441620 scopus 로고    scopus 로고
    • 177Lu -J591 for Metastatic Castrate Resistant Prostate Cancer (metCRPC)
    • Abst TPS247
    • 177Lu -J591 for Metastatic Castrate Resistant Prostate Cancer (metCRPC). J Clin Oncol 2010; 28 (Suppl.): Abst TPS247
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL.
    • Beltran, H.1    Vallabhajosula, S.2    Kelly, W.K.3
  • 83
    • 80052683665 scopus 로고    scopus 로고
    • 177Lu-J591) and ketoconazole in patients (pts) with high-risk castrate biochemically relapsed prostate cancer (PC) after local therapy
    • Abst TPS248
    • 177Lu-J591) and ketoconazole in patients (pts) with high-risk castrate biochemically relapsed prostate cancer (PC) after local therapy. J Clin Oncol 2010; 28 (Suppl.): Abst TPS248
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL.
    • Tagawa, S.T.1    Osborne, J.2    Christos, P.J.3
  • 84
    • 70349740108 scopus 로고    scopus 로고
    • Phase II multicenter study of chemotherapy (chemo)-naive castration-resistant prostate cancer not exposed to ketoconazole (keto), treated with abiraterone acetate (AA) plus prednisone
    • Ryan C, Efstathiou E, Smith M, et al,. Phase II multicenter study of chemotherapy (chemo)-naive castration-resistant prostate cancer not exposed to ketoconazole (keto), treated with abiraterone acetate (AA) plus prednisone. J Clin Oncol 2009; 27: 5046
    • (2009) J Clin Oncol , vol.27 , pp. 5046
    • Ryan, C.1    Efstathiou, E.2    Smith, M.3
  • 85
    • 77951591066 scopus 로고    scopus 로고
    • Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer
    • Danila DC, Morris MJ, de Bono JS, et al,. Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer. J Clin Oncol 2010; 28: 1496-501
    • (2010) J Clin Oncol , vol.28 , pp. 1496-1501
    • Danila, D.C.1    Morris, M.J.2    De Bono, J.S.3
  • 86
    • 80054054179 scopus 로고    scopus 로고
    • Abiraterone acetate (AA) plus low dose prednisone (P) improves overall survival (OS) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) who have progressed after docetaxel-based chemotherapy (chemo): Results of COU-AA-301, a randomized, double-blind, placebo-controlled phase III study
    • Abstract LBA5
    • De Bono J, Logothetis CJ, Fizazi K, et al,. Abiraterone acetate (AA) plus low dose prednisone (P) improves overall survival (OS) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) who have progressed after docetaxel-based chemotherapy (chemo): results of COU-AA-301, a randomized, double-blind, placebo-controlled phase III study. 35th ESMO Congress. 2010; Abstract LBA5
    • (2010) 35th ESMO Congress
    • De Bono, J.1    Logothetis, C.J.2    Fizazi, K.3
  • 89
    • 77949412572 scopus 로고    scopus 로고
    • A phase II study of paclitaxel poliglumex in combination with transdermal estradiol for the treatment of metastatic castration-resistant prostate cancer after docetaxel chemotherapy
    • Beer TM, Ryan C, Alumkal J, Ryan CW, Sun J, Eilers KM,. A phase II study of paclitaxel poliglumex in combination with transdermal estradiol for the treatment of metastatic castration-resistant prostate cancer after docetaxel chemotherapy. Anticancer Drugs 2010; 21: 433-8
    • (2010) Anticancer Drugs , vol.21 , pp. 433-438
    • Beer, T.M.1    Ryan, C.2    Alumkal, J.3    Ryan, C.W.4    Sun, J.5    Eilers, K.M.6
  • 90
    • 77957682309 scopus 로고    scopus 로고
    • Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
    • de Bono J, Oudard S, Ozguroglu M, et al,. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet 2010; 376: 1147-54
    • (2010) Lancet , vol.376 , pp. 1147-1154
    • De Bono, J.1    Oudard, S.2    Ozguroglu, M.3
  • 91
    • 53249120043 scopus 로고    scopus 로고
    • Satraplatin in patients with advanced hormone-refractory prostate cancer (HRPC): Overall survival (OS) results from the phase III satraplatin and prednisone against refractory cancer (SPARC) trial
    • (Meeting Abstracts)
    • Sartor AO, Petrylak DP, Witjes JA, et al,. Satraplatin in patients with advanced hormone-refractory prostate cancer (HRPC): overall survival (OS) results from the phase III satraplatin and prednisone against refractory cancer (SPARC) trial. J Clin Oncol 2008; 26: 5003 (Meeting Abstracts)
    • (2008) J Clin Oncol , vol.26 , pp. 5003
    • Sartor, A.O.1    Petrylak, D.P.2    Witjes, J.A.3
  • 92
    • 34547119271 scopus 로고    scopus 로고
    • Activity of second-line chemotherapy in docetaxel-refractory hormone-refractory prostate cancer patients: Randomized phase 2 study of ixabepilone or mitoxantrone and prednisone
    • DOI 10.1002/cncr.22811
    • Rosenberg JE, Weinberg VK, Kelly WK, et al,. Activity of second-line chemotherapy in docetaxel-refractory hormone-refractory prostate cancer patients: randomized phase 2 study of ixabepilone or mitoxantrone and prednisone. Cancer 2007; 110: 556-63 (Pubitemid 47106144)
    • (2007) Cancer , vol.110 , Issue.3 , pp. 556-563
    • Rosenberg, J.E.1    Weinberg, V.K.2    Kelly, W.K.3    Michaelson, D.4    Hussain, M.H.5    Wilding, G.6    Gross, M.7    Hutcheon, D.8    Small, E.J.9
  • 93
    • 79953693527 scopus 로고    scopus 로고
    • Ixabepilone, mitoxantrone, and prednisone for metastatic castration-resistant prostate cancer after docetaxel-based therapy: A phase 2 study of the department of defense prostate cancer clinical trials consortium
    • [Epub ahead of print]. DOI: 10.1002/cncr.25810
    • Harzstark AL, Rosenberg JE, Weinberg VK, et al,. Ixabepilone, mitoxantrone, and prednisone for metastatic castration-resistant prostate cancer after docetaxel-based therapy: a phase 2 study of the department of defense prostate cancer clinical trials consortium. Cancer 2010; [Epub ahead of print]. DOI: 10.1002/cncr.25810
    • (2010) Cancer
    • Harzstark, A.L.1    Rosenberg, J.E.2    Weinberg, V.K.3
  • 94
    • 77949876930 scopus 로고    scopus 로고
    • A phase II study of patupilone in patients (pts) with metastatic castration- resistant prostate cancer (CRPC) who have progressed after docetaxel
    • (Meeting Abstracts)
    • Beardsley EK, Saad F, Eigl B, et al,. A phase II study of patupilone in patients (pts) with metastatic castration- resistant prostate cancer (CRPC) who have progressed after docetaxel. J Clin Oncol 2009; 27: 5139 (Meeting Abstracts)
    • (2009) J Clin Oncol , vol.27 , pp. 5139
    • Beardsley, E.K.1    Saad, F.2    Eigl, B.3
  • 95
    • 29844447100 scopus 로고    scopus 로고
    • A retrospective evaluation of second-line chemotherapy response in hormone-refractory prostate carcinoma: Second-line taxane-based therapy after first-line epothilone-B analog ixahepilone (BMS-247550) therapy
    • DOI 10.1002/cncr.21559
    • Rosenberg J, Galsky M, Rohs N, et al,. A retrospective evaluation of second-line chemotherapy response in hormone-refractory prostate carcinoma: second line taxane-based therapy after first-line epothilone-B analog ixabepilone (BMS-247550) therapy. Cancer 2006; 106: 58-62 (Pubitemid 43033322)
    • (2006) Cancer , vol.106 , Issue.1 , pp. 58-62
    • Rosenberg, J.E.1    Galsky, M.D.2    Rohs, N.C.3    Weinberg, V.K.4    Oh, W.K.5    Kelly, W.K.6    Small, E.J.7
  • 96
    • 0037009822 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma
    • Saad F, Gleason D, Murray R, et al,. A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma. J Natl Cancer Inst 2002; 94: 1458-68
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1458-1468
    • Saad, F.1    Gleason, D.2    Murray, R.3
  • 98
    • 0642337996 scopus 로고    scopus 로고
    • Combined analysis of two multicenter, randomized, placebo-controlled studies of pamidronate disodium for the palliation of bone pain in men with metastatic prostate cancer
    • DOI 10.1200/JCO.2003.05.147
    • Small E, Smith M, Seaman J, Petrone S, Kowalski M,. Combined analysis of two multicenter, randomized, placebo-controlled studies of pamidronate disodium for the palliation of bone pain in men with metastatic prostate cancer. J Clin Oncol 2003; 21: 4277-84 (Pubitemid 46621802)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.23 , pp. 4277-4284
    • Small, E.J.1    Smith, M.R.2    Seaman, J.J.3    Petrone, S.4    Kowalski, M.O.5
  • 99
    • 0141688330 scopus 로고    scopus 로고
    • Randomized, double-blind, controlled trial of mitoxantrone/prednisone and clodronate versus mitoxantrone/prednisone and placebo in patients with hormone-refractory prostate cancer and pain
    • DOI 10.1200/JCO.2003.03.042
    • Ernst D, Tannock I, Winquist E, et al,. Randomized, double-blind, controlled trial of mitoxantrone/prednisone and clodronate versus mitoxantrone/prednisone and placebo in patients with hormone-refractory prostate cancer and pain. J Clin Oncol 2003; 21: 3335-42 (Pubitemid 46613484)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.17 , pp. 3335-3342
    • Ernst, D.S.1    Tannock, I.F.2    Winquist, E.W.3    Venner, P.M.4    Reyno, L.5    Moore, M.J.6    Chi, K.7    Ding, K.8    Elliott, C.9    Parulekar, W.10
  • 100
    • 78349290889 scopus 로고    scopus 로고
    • A randomized phase III trial of denosumab versus zoledronic acid in patients with bone metastases from castration-resistant prostate cancer
    • (LBA4507) (Meeting Abstracts)
    • Fizazi K, Carducci MA, Smith MR, et al,. A randomized phase III trial of denosumab versus zoledronic acid in patients with bone metastases from castration-resistant prostate cancer. J Clin Oncol 2010; 28: 18s (LBA4507) (Meeting Abstracts)
    • (2010) J Clin Oncol , vol.28
    • Fizazi, K.1    Carducci, M.A.2    Smith, M.R.3
  • 103
    • 0037086536 scopus 로고    scopus 로고
    • A multiinstitutional, concurrent chemoradiation trial of strontium-89, estramustine, and vinblastine for hormone refractory prostate carcinoma involving bone
    • DOI 10.1002/cncr.10437
    • Akerley W, Butera J, Wehbe T, et al,. A multiinstitutional, concurrent chemoradiation trial of strontium-89, estramustine, and vinblastine for hormone refractory prostate carcinoma involving bone. Cancer 2002; 94: 1654-60 (Pubitemid 34241101)
    • (2002) Cancer , vol.94 , Issue.6 , pp. 1654-1660
    • Akerley, W.1    Butera, J.2    Wehbe, T.3    Noto, R.4    Stein, B.5    Safran, H.6    Cummings, F.7    Sambandam, S.8    Maynard, J.9    Di Rienzo, G.10    Leone, L.11
  • 105
    • 66349089867 scopus 로고    scopus 로고
    • Phase II trial of consolidation docetaxel and samarium-153 in patients with bone metastases from castration-resistant prostate cancer
    • Fizazi K, Beuzeboc P, Lumbroso J, et al,. Phase II trial of consolidation docetaxel and samarium-153 in patients with bone metastases from castration-resistant prostate cancer. J Clin Oncol 2009; 27: 2429-35
    • (2009) J Clin Oncol , vol.27 , pp. 2429-2435
    • Fizazi, K.1    Beuzeboc, P.2    Lumbroso, J.3
  • 108
    • 69049105440 scopus 로고    scopus 로고
    • Denosumab in men receiving androgen-deprivation therapy for prostate cancer
    • Smith MR, Egerdie B, Hernandez Toriz N, et al,. Denosumab in men receiving androgen-deprivation therapy for prostate cancer. N Engl J Med 2009; 361: 745-55
    • (2009) N Engl J Med , vol.361 , pp. 745-755
    • Smith, M.R.1    Egerdie, B.2    Hernandez Toriz, N.3
  • 109
    • 0035260751 scopus 로고    scopus 로고
    • Painful osteoblastic metastases: The role of nuclear medicine
    • Silberstein E, Eugene L, Saenger S,. Painful osteoblastic metastases: the role of nuclear medicine. Oncology 2001; 15: 157-63 (Pubitemid 33739474)
    • (2001) ONCOLOGY , vol.15 , Issue.2 , pp. 157-163
    • Silberstein, E.B.1


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