Contribution of active site glutamine to rate enhancement in ubiquitin C-terminal hydrolases

FEBS Journal

Volumn 279, Issue 6, 2012, Pages 1106-1118

  Boudreaux, David A ^a   Chaney, Joseph ^a   Maiti, Tushar K ^a,b   Das, Chittaranjan ^a  

^a PURDUE UNIVERSITY   (United States)

^b NONE   (India)

Author keywords

CHO hydrogen bond; cysteine proteases; deubiquitinases; oxyanion hole; UCH enzymes

Indexed keywords

ALANINE; CYSTEINE PROTEINASE; GLUTAMINE; GLYCINE; HISTIDINE; HYDROGEN; LYSINE; OXYGEN; PAPAIN; UBIQUITIN C TERMINAL HYDROLASE 1; UBIQUITIN C TERMINAL HYDROLASE 3; UBIQUITIN C TERMINAL HYDROLASE 5; UBIQUITIN THIOLESTERASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; MOLECULAR INTERACTION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; STRUCTURE ANALYSIS; WILD TYPE;

EID: 84858439741     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2012.08507.x     Document Type: Article

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