메뉴 건너뛰기




Volumn 31, Issue 1, 2013, Pages 3-11

Clopidogrel "Resistance": Where are We Now?

Author keywords

Coagulation Thrombosis; Interventional cardiology; Ischemic heart disease; Vascular biology

Indexed keywords

CLOPIDOGREL;

EID: 84872330167     PISSN: 17555914     EISSN: 17555922     Source Type: Journal    
DOI: 10.1111/j.1755-5922.2011.00296.x     Document Type: Article
Times cited : (31)

References (95)
  • 1
    • 9244251971 scopus 로고    scopus 로고
    • A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents
    • Schomig A, Neumann FJ, Kastrati A, et al. A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents. N Engl J Med 1996;334:1084-1089.
    • (1996) N Engl J Med , vol.334 , pp. 1084-1089
    • Schomig, A.1    Neumann, F.J.2    Kastrati, A.3
  • 2
    • 1642494610 scopus 로고    scopus 로고
    • Antiplatelet therapy for elective coronary stenting: A moving target
    • Claeys MJ. Antiplatelet therapy for elective coronary stenting: A moving target. Semin Vasc Med 2003;3:415-418.
    • (2003) Semin Vasc Med , vol.3 , pp. 415-418
    • Claeys, M.J.1
  • 3
    • 49349114160 scopus 로고    scopus 로고
    • Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents
    • Gori AM, Marcucci R, Migliorini A, et al. Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents. J Am Coll Cardiol 2008;52:734-739.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 734-739
    • Gori, A.M.1    Marcucci, R.2    Migliorini, A.3
  • 4
    • 34250020766 scopus 로고    scopus 로고
    • Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis
    • Buonamici P, Marcucci R, Migliorini A, et al. Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis. J Am Coll Cardiol 2007;49:2312-2317.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2312-2317
    • Buonamici, P.1    Marcucci, R.2    Migliorini, A.3
  • 5
    • 33750479499 scopus 로고    scopus 로고
    • Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement
    • Hochholzer W, Trenk D, Bestehorn HP, et al. Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement. J Am Coll Cardiol 2006;48:1742-1750.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1742-1750
    • Hochholzer, W.1    Trenk, D.2    Bestehorn, H.P.3
  • 6
    • 84872313603 scopus 로고    scopus 로고
    • FDA Drug Safety Communication. Reduced effectiveness of Plavix (clopidogrel) in patients who are poor metabolizers of the drug. Available from Accessed 8 July
    • FDA Drug Safety Communication. Reduced effectiveness of Plavix (clopidogrel) in patients who are poor metabolizers of the drug. Available from: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm203888.htm [Accessed 8 July 2011].
    • (2011)
  • 7
    • 77955638355 scopus 로고    scopus 로고
    • ACCF/AHA clopidogrel clinical alert: Approaches to the FDA "boxed warning": A report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons
    • Holmes DR Jr, Dehmer GJ, Kaul S, Leifer D, O'Gara PT, Stein CM. ACCF/AHA clopidogrel clinical alert: Approaches to the FDA "boxed warning": A report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol 2010;56:321-341.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 321-341
    • Holmes Jr, D.R.1    Dehmer, G.J.2    Kaul, S.3    Leifer, D.4    O'Gara, P.T.5    Stein, C.M.6
  • 8
    • 34249990913 scopus 로고    scopus 로고
    • Clopidogrel resistance?
    • Gurbel PA, Tantry US. Clopidogrel resistance?Thromb Res 2007;120;311-321.
    • (2007) Thromb Res , vol.120 , pp. 311-321
    • Gurbel, P.A.1    Tantry, U.S.2
  • 9
    • 33751546229 scopus 로고    scopus 로고
    • Thrombelastography: Current clinical applications and its potential role in interventional cardiology
    • Hobson AR, Agarwala RA, Swallow RA, Dawkins KD, Curzen NP. Thrombelastography: Current clinical applications and its potential role in interventional cardiology. Platelets 2006;17:509-518.
    • (2006) Platelets , vol.17 , pp. 509-518
    • Hobson, A.R.1    Agarwala, R.A.2    Swallow, R.A.3    Dawkins, K.D.4    Curzen, N.P.5
  • 10
    • 77952229611 scopus 로고    scopus 로고
    • Effects of clopidogrel on "aspirin specific" pathways of platelet inhibition
    • Hobson A, Qureshi Z, Banks P, Curzen N. Effects of clopidogrel on "aspirin specific" pathways of platelet inhibition. Platelets 2009;20:386-390.
    • (2009) Platelets , vol.20 , pp. 386-390
    • Hobson, A.1    Qureshi, Z.2    Banks, P.3    Curzen, N.4
  • 11
    • 35649021844 scopus 로고    scopus 로고
    • A novel fifteen minute test for the assessment of individual time dependent clotting responses to aspirin and clopidogrel using modified thrombelastography
    • Hobson AR, Petley GW, Dawkins KD, Curzen N. A novel fifteen minute test for the assessment of individual time dependent clotting responses to aspirin and clopidogrel using modified thrombelastography. Platelets 2007;18:497-505.
    • (2007) Platelets , vol.18 , pp. 497-505
    • Hobson, A.R.1    Petley, G.W.2    Dawkins, K.D.3    Curzen, N.4
  • 12
    • 0034762075 scopus 로고    scopus 로고
    • Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement
    • Muller I, Seyfarth M, Rudiger S, Wolf B, Pogatsa-Murray G, Schomig A, Gawaz M. Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement. Heart 2001;85:92-93.
    • (2001) Heart , vol.85 , pp. 92-93
    • Muller, I.1    Seyfarth, M.2    Rudiger, S.3    Wolf, B.4    Pogatsa-Murray, G.5    Schomig, A.6    Gawaz, M.7
  • 13
    • 0033545889 scopus 로고    scopus 로고
    • Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin in preventing stent thrombosis after coronary stent implantation
    • Moussa I, Oetgen M, Roubin G, et al. Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin in preventing stent thrombosis after coronary stent implantation. Circulation 1999;99:2364-2366.
    • (1999) Circulation , vol.99 , pp. 2364-2366
    • Moussa, I.1    Oetgen, M.2    Roubin, G.3
  • 15
    • 70450199115 scopus 로고    scopus 로고
    • 2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (Updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (Updating the 2005 Guideline and 2007 Focused Update): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • Kushner GF, Hand M, Smith SC, et al. 2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (Updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (Updating the 2005 Guideline and 2007 Focused Update): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2009;54:2205-2241.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 2205-2241
    • Kushner, G.F.1    Hand, M.2    Smith, S.C.3
  • 16
    • 9644281092 scopus 로고    scopus 로고
    • Identification of low responders to a 300-mg clopidogrel loading dose in patients undergoing coronary stenting
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. Identification of low responders to a 300-mg clopidogrel loading dose in patients undergoing coronary stenting. Thromb Res 2005;115:101-108.
    • (2005) Thromb Res , vol.115 , pp. 101-108
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3
  • 17
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • CURE Steering Committee.
    • CURE Steering Committee. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001;345:494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
  • 18
    • 27644548513 scopus 로고    scopus 로고
    • Addition of clopidogrel to aspirin in 45 852 patients with acute myocardial infarction: Randomised, placebo-controlled trial
    • COMMIT Collaborative Group.
    • COMMIT Collaborative Group. Addition of clopidogrel to aspirin in 45 852 patients with acute myocardial infarction: Randomised, placebo-controlled trial. Lancet 2005;366:1607-1621.
    • (2005) Lancet , vol.366 , pp. 1607-1621
  • 19
    • 20144373281 scopus 로고    scopus 로고
    • Addition of clopidogrel to aspirin and fibrinolytic therapy for Myocardial infarction with ST-segment elevation
    • CLARITY-TIMI 28 Investigators.
    • CLARITY-TIMI 28 Investigators. Addition of clopidogrel to aspirin and fibrinolytic therapy for Myocardial infarction with ST-segment elevation. N Engl J Med 2005;352:1179-1189.
    • (2005) N Engl J Med , vol.352 , pp. 1179-1189
  • 20
    • 0035908781 scopus 로고    scopus 로고
    • Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: The PCI-CURE study
    • Mehta SR, Yusuf S, Peters RJ, et al. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: The PCI-CURE study. Lancet 2001;358:527-533.
    • (2001) Lancet , vol.358 , pp. 527-533
    • Mehta, S.R.1    Yusuf, S.2    Peters, R.J.3
  • 21
    • 33746206423 scopus 로고    scopus 로고
    • Rationale and design of ACTIVE: The atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events
    • Active Steering Committee.
    • Active Steering Committee. Rationale and design of ACTIVE: The atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events. Am Heart J 2006;151:1187-1193.
    • (2006) Am Heart J , vol.151 , pp. 1187-1193
  • 22
    • 77958128969 scopus 로고    scopus 로고
    • Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)
    • Wijns W, Kolh P, Danchin N, et al. Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J 2010;20:2501-2555.
    • (2010) Eur Heart J , vol.20 , pp. 2501-2555
    • Wijns, W.1    Kolh, P.2    Danchin, N.3
  • 23
    • 20344408497 scopus 로고    scopus 로고
    • Stent Thrombosis is associated with an impaired response to anti-platelet therapy
    • Wenaweser P, Hess O. Stent Thrombosis is associated with an impaired response to anti-platelet therapy. J Am Coll Cardiol 2005;45:1748-1752.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1748-1752
    • Wenaweser, P.1    Hess, O.2
  • 25
    • 41149115763 scopus 로고    scopus 로고
    • Point-of-care platelet function assays demonstrate reduced responsiveness to clopidogrel, but not aspirin, in patients with Drug-Eluting Stent Thrombosis whilst on dual antiplatelet therapy
    • Hobson AR, Petley G, Morton G, Dawkins KD, Curzen NP. Point-of-care platelet function assays demonstrate reduced responsiveness to clopidogrel, but not aspirin, in patients with Drug-Eluting Stent Thrombosis whilst on dual antiplatelet therapy. Thrombs J 2008;6:1.
    • (2008) Thrombs J , vol.6 , pp. 1
    • Hobson, A.R.1    Petley, G.2    Morton, G.3    Dawkins, K.D.4    Curzen, N.P.5
  • 26
    • 17744376570 scopus 로고    scopus 로고
    • Randomized trial of high loading dose of clopidogrel for reduction of periprocedural myocardial infarction in patients undergoing coronary intervention
    • Patti G, Colonna G, Pasceri V, Pepe LL, Montinaro A, Di Sciascio G. Randomized trial of high loading dose of clopidogrel for reduction of periprocedural myocardial infarction in patients undergoing coronary intervention. Circulation 2005;111:2009-2106.
    • (2005) Circulation , vol.111 , pp. 2009-2106
    • Patti, G.1    Colonna, G.2    Pasceri, V.3    Pepe, L.L.4    Montinaro, A.5    Di Sciascio, G.6
  • 27
    • 18144371221 scopus 로고    scopus 로고
    • The relation of dosing to clopidogrel responsiveness and the incidence of high post treatment platelet aggregation in patients undergoing coronary stenting
    • Gurbel PA, Bliden KP, Hayes KM, Yoho JA, Herzog WR, Tantry US. The relation of dosing to clopidogrel responsiveness and the incidence of high post treatment platelet aggregation in patients undergoing coronary stenting. J Am Coll Cardiol 2005;45:1392-1396.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1392-1396
    • Gurbel, P.A.1    Bliden, K.P.2    Hayes, K.M.3    Yoho, J.A.4    Herzog, W.R.5    Tantry, U.S.6
  • 28
    • 7544239072 scopus 로고    scopus 로고
    • High clopidogrel loading dose during coronary stenting: Effect on drug response and interindividual variability
    • Angiolillo DJ, Fernandez OA, Bernardo E, et al. High clopidogrel loading dose during coronary stenting: Effect on drug response and interindividual variability. Eur Heart J 2004;25:1903-1910.
    • (2004) Eur Heart J , vol.25 , pp. 1903-1910
    • Angiolillo, D.J.1    Fernandez, O.A.2    Bernardo, E.3
  • 29
    • 33747874088 scopus 로고    scopus 로고
    • A randomized comparison of high clopidogrel LDs in patients with non-ST-segment elevation acute coronary syndromes: The ALBION (Assessment of the Best LD of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial
    • ALBION Trial Investigators.
    • ALBION Trial Investigators. A randomized comparison of high clopidogrel LDs in patients with non-ST-segment elevation acute coronary syndromes: The ALBION (Assessment of the Best LD of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial. J Am Coll Cardiol 2006;48:931-938.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 931-938
  • 30
    • 27744516843 scopus 로고    scopus 로고
    • Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg LDs of clopidogrel: Results of the ISAR-CHOICE (Intracoronary Stenting and Antithrombotic Regimen: Choose Between 3 High Oral Doses for Immediate Clopidogrel Effect) Trial
    • von Beckerath N, Taubert D, Pogatsa-Murray G, Schömig E, Kastrati A, Schömig A. Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg LDs of clopidogrel: Results of the ISAR-CHOICE (Intracoronary Stenting and Antithrombotic Regimen: Choose Between 3 High Oral Doses for Immediate Clopidogrel Effect) Trial. Circulation 2005;112:2946-2950.
    • (2005) Circulation , vol.112 , pp. 2946-2950
    • von Beckerath, N.1    Taubert, D.2    Pogatsa-Murray, G.3    Schömig, E.4    Kastrati, A.5    Schömig, A.6
  • 31
    • 33646551868 scopus 로고    scopus 로고
    • Onset and offset of platelet inhibition after high-dose clopidogrel loading and standard daily therapy measured by a point-of-care assay in healthy volunteers
    • Price MJ, Coleman JL, Steinhubl SR, Wong GB, Cannon CP, Teirstein PS. Onset and offset of platelet inhibition after high-dose clopidogrel loading and standard daily therapy measured by a point-of-care assay in healthy volunteers. Am J Cardiol 2006;98:681-684.
    • (2006) Am J Cardiol , vol.98 , pp. 681-684
    • Price, M.J.1    Coleman, J.L.2    Steinhubl, S.R.3    Wong, G.B.4    Cannon, C.P.5    Teirstein, P.S.6
  • 32
    • 84872315478 scopus 로고    scopus 로고
    • The potential value of near patient platelet function testing in PCI: Randomised comparison of 600 mg versus 900 mg clopidogrel loading doses
    • doi:10.1155/2010/908272.
    • Hobson A, Qureshi Z, Banks P, Curzen N. The potential value of near patient platelet function testing in PCI: Randomised comparison of 600 mg versus 900 mg clopidogrel loading doses. Thrombosis 2010. doi:10.1155/2010/908272.
    • (2010) Thrombosis
    • Hobson, A.1    Qureshi, Z.2    Banks, P.3    Curzen, N.4
  • 33
    • 57549109044 scopus 로고    scopus 로고
    • The antiplatelet effect of higher loading and maintenance dose regimens of clopidogrel the PRINC (Plavix Response in Coronary Intervention) trial
    • Gladding P, Webster M, Zeng I, et al. The antiplatelet effect of higher loading and maintenance dose regimens of clopidogrel the PRINC (Plavix Response in Coronary Intervention) trial. J Am Coll Cardiol Intv 2008;1:612-619.
    • (2008) J Am Coll Cardiol Intv , vol.1 , pp. 612-619
    • Gladding, P.1    Webster, M.2    Zeng, I.3
  • 34
    • 41249093357 scopus 로고    scopus 로고
    • Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: A multicenter randomized prospective study
    • Bonello L, Camoin-Jau L, Arques S, et al. Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: A multicenter randomized prospective study. J Am Coll Cardiol 2008;51:1404-1411.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1404-1411
    • Bonello, L.1    Camoin-Jau, L.2    Arques, S.3
  • 35
    • 34248397644 scopus 로고    scopus 로고
    • A double blind, randomized study on platelet aggregation in patients treated with a daily dose of 150 mg or 75 mg of clopidogrel for 30 days
    • Von Beckerath N, Kastrati A, Wieczorek A, Pogatsa-Murray G, Sibbing D, Graf I, Schomig A. A double blind, randomized study on platelet aggregation in patients treated with a daily dose of 150 mg or 75 mg of clopidogrel for 30 days. Eur Heart J 2007;28:1814-1819.
    • (2007) Eur Heart J , vol.28 , pp. 1814-1819
    • Von Beckerath, N.1    Kastrati, A.2    Wieczorek, A.3    Pogatsa-Murray, G.4    Sibbing, D.5    Graf, I.6    Schomig, A.7
  • 36
    • 33745960402 scopus 로고    scopus 로고
    • Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: Results from the PREMIER registry
    • Spretus JA, Kettelkamp R, Vance C, et al. Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: Results from the PREMIER registry. Circulation 2006;113:2803-2809.
    • (2006) Circulation , vol.113 , pp. 2803-2809
    • Spretus, J.A.1    Kettelkamp, R.2    Vance, C.3
  • 37
    • 17844373254 scopus 로고    scopus 로고
    • Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents
    • Iakovou I, Schmidt T, Bonizzoni E, et al. Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA 2005;293:2126-2130.
    • (2005) JAMA , vol.293 , pp. 2126-2130
    • Iakovou, I.1    Schmidt, T.2    Bonizzoni, E.3
  • 38
    • 64049096437 scopus 로고    scopus 로고
    • Predictors of coronary stent thrombosis: The Dutch Stent Thrombosis Registry
    • van Werkum JW, Heestermans AA, Zomer AC, et al. Predictors of coronary stent thrombosis: The Dutch Stent Thrombosis Registry. J Am Coll Cardiol 2009;53:1399-1409.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1399-1409
    • van Werkum, J.W.1    Heestermans, A.A.2    Zomer, A.C.3
  • 39
    • 61349100778 scopus 로고    scopus 로고
    • Temporal relation between clopidodgrel cessation and stent thrombosis after drug-eluting stent implantation
    • Roy P, Bonello L, Torguson R, et al. Temporal relation between clopidodgrel cessation and stent thrombosis after drug-eluting stent implantation. Am J Cardiol 2009;103:801-805.
    • (2009) Am J Cardiol , vol.103 , pp. 801-805
    • Roy, P.1    Bonello, L.2    Torguson, R.3
  • 40
    • 33847167065 scopus 로고    scopus 로고
    • Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: Data from a large two-institutional cohort study
    • Daemen J, Wenaweser P, Tsuchida K, et al. Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: Data from a large two-institutional cohort study. Lancet 2007;369:667-678.
    • (2007) Lancet , vol.369 , pp. 667-678
    • Daemen, J.1    Wenaweser, P.2    Tsuchida, K.3
  • 41
    • 9644281093 scopus 로고    scopus 로고
    • The difference between clopidogrel responsiveness and post treatment platelet reactivity
    • Samara WM Bliden KP, Tantry US, Gurbel PA. The difference between clopidogrel responsiveness and post treatment platelet reactivity. Thromb Res 2005;115:89-94.
    • (2005) Thromb Res , vol.115 , pp. 89-94
    • Samara, W.M.1    Bliden, K.P.2    Tantry, U.S.3    Gurbel, P.A.4
  • 43
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • Simon T, Verstuyft C, Mary-Krause M, et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med. 2009;360:363-375.
    • (2009) N Engl J Med. , vol.360 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 44
    • 34249990913 scopus 로고    scopus 로고
    • Clopidogrel resistance?
    • Gurbel P, Tantry US. Clopidogrel resistance?Thromb Res 2007;120:311-321.
    • (2007) Thromb Res , vol.120 , pp. 311-321
    • Gurbel, P.1    Tantry, U.S.2
  • 45
    • 33744968214 scopus 로고    scopus 로고
    • Increased risk of atherothrombotic events associated with cytochrome P450 3A5 polymorphism in patients taking clopidogrel
    • Suh JW, Koo BK, Zhang SY, et al. Increased risk of atherothrombotic events associated with cytochrome P450 3A5 polymorphism in patients taking clopidogrel. CMAJ 2006;174:1715-1722.
    • (2006) CMAJ , vol.174 , pp. 1715-1722
    • Suh, J.W.1    Koo, B.K.2    Zhang, S.Y.3
  • 46
    • 1642453779 scopus 로고    scopus 로고
    • Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance
    • Lau WC, Gurbel PA, Watkins PB, et al. Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance. Circulation 2004;109:166-171.
    • (2004) Circulation , vol.109 , pp. 166-171
    • Lau, W.C.1    Gurbel, P.A.2    Watkins, P.B.3
  • 47
    • 43049179414 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents
    • Trenk D, Hochholzer W, Fromm MF, et al. Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents. J Am Coll Cardiol 2008;51:1925-1934.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1925-1934
    • Trenk, D.1    Hochholzer, W.2    Fromm, M.F.3
  • 48
    • 30344457586 scopus 로고    scopus 로고
    • A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants
    • Sim SC, Risinger C, Dahl ML, Aklillu E, Christensen M, Bertilsson L, Ingelman-Sundberg M. A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants. Clin Pharmacol Ther 2006;79:103-113.
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 103-113
    • Sim, S.C.1    Risinger, C.2    Dahl, M.L.3    Aklillu, E.4    Christensen, M.5    Bertilsson, L.6    Ingelman-Sundberg, M.7
  • 51
    • 0042859862 scopus 로고    scopus 로고
    • Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects
    • Fontana P, Dupont A, Gandrille S, Bachelot-Loza C, Reny JL, Aiach M, Gaussem P. Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects. Circulation 2003;108:989-995.
    • (2003) Circulation , vol.108 , pp. 989-995
    • Fontana, P.1    Dupont, A.2    Gandrille, S.3    Bachelot-Loza, C.4    Reny, J.L.5    Aiach, M.6    Gaussem, P.7
  • 52
    • 11144357704 scopus 로고    scopus 로고
    • PIA polymorphism and platelet reactivity following clopidogrel loading dose in patients undergoing coronary stent implantation
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. PIA polymorphism and platelet reactivity following clopidogrel loading dose in patients undergoing coronary stent implantation. Blood Coagul Fibrinolysis 2004;15:89-93.
    • (2004) Blood Coagul Fibrinolysis , vol.15 , pp. 89-93
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3
  • 53
    • 24944465039 scopus 로고    scopus 로고
    • Lack of association between the P2Y12 receptor gene polymorphism and platelet response to clopidogrel in patients with coronary artery disease
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. Lack of association between the P2Y12 receptor gene polymorphism and platelet response to clopidogrel in patients with coronary artery disease. Thromb Res 2005;116:491-497.
    • (2005) Thromb Res , vol.116 , pp. 491-497
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3
  • 54
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • Simon T, Verstuyft C, Mary-Krause M, et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med 2009;360:363-375.
    • (2009) N Engl J Med , vol.360 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 55
    • 31644438586 scopus 로고    scopus 로고
    • Effect of platelet antigen polymorphism on platelet inhibition by aspirin, clopidogrel, or their combination
    • Cooke GE, Liu-Stratton Y, Ferketich AK, et al. Effect of platelet antigen polymorphism on platelet inhibition by aspirin, clopidogrel, or their combination. J Am Coll Cardiol 2006;47:541-546.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 541-546
    • Cooke, G.E.1    Liu-Stratton, Y.2    Ferketich, A.K.3
  • 56
    • 33748125605 scopus 로고    scopus 로고
    • Polymorphisms of the GP IIIa and P2Y12 receptors and modulation of antiplatelet effects of combined aspirin and clopidogrel treatment (abstr)
    • Angiolillo DJ, Bernardo E, Ramirez C, et al. Polymorphisms of the GP IIIa and P2Y12 receptors and modulation of antiplatelet effects of combined aspirin and clopidogrel treatment (abstr). Circulation 2004;110:2013.
    • (2004) Circulation , vol.110 , pp. 2013
    • Angiolillo, D.J.1    Bernardo, E.2    Ramirez, C.3
  • 57
    • 3142512587 scopus 로고    scopus 로고
    • 807 C/T polymorphism of the glycoprotein Ia gene and pharmacogenetic modulation of platelet response to dual antiplatelet treatment
    • Angiolillo DJ, Fernández-Ortiz A, Bernardo E, et al. 807 C/T polymorphism of the glycoprotein Ia gene and pharmacogenetic modulation of platelet response to dual antiplatelet treatment. Blood Coagul Fibrinolysis 2004;15:427-433.
    • (2004) Blood Coagul Fibrinolysis , vol.15 , pp. 427-433
    • Angiolillo, D.J.1    Fernández-Ortiz, A.2    Bernardo, E.3
  • 58
    • 23644433510 scopus 로고    scopus 로고
    • Platelet function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopidogrel treatment
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. Platelet function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopidogrel treatment. Diabetes 2005;54:2430-2435.
    • (2005) Diabetes , vol.54 , pp. 2430-2435
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3
  • 59
    • 33745815689 scopus 로고    scopus 로고
    • Insulin therapy is associated with platelet dysfunction in patients with type 2 diabetes mellitus on dual oral antiplatelet treatment
    • Angiolillo DJ, Bernardo E, Ramirez C, et al. Insulin therapy is associated with platelet dysfunction in patients with type 2 diabetes mellitus on dual oral antiplatelet treatment. J Am Coll Cardiol 2006;48:298-304.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 298-304
    • Angiolillo, D.J.1    Bernardo, E.2    Ramirez, C.3
  • 60
    • 27644536235 scopus 로고    scopus 로고
    • Platelet reactivity in patients and recurrent events post-stenting: Results of the PREPARE POST-STENTING Study
    • Gurbel PA, Bliden KP, Guyer K, et al. Platelet reactivity in patients and recurrent events post-stenting: Results of the PREPARE POST-STENTING Study. J Am Coll Cardiol 2005;46:1820-1826.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1820-1826
    • Gurbel, P.A.1    Bliden, K.P.2    Guyer, K.3
  • 62
    • 29344466941 scopus 로고    scopus 로고
    • Aspirin and clopidogrel drug response in patients undergoing percutaneous intervention: The role of dual drug resistance
    • Lev EI, Patel RT, Maresh KJ, et al. Aspirin and clopidogrel drug response in patients undergoing percutaneous intervention: The role of dual drug resistance. J Am Coll Cardiol 2006;47:27-33.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 27-33
    • Lev, E.I.1    Patel, R.T.2    Maresh, K.J.3
  • 63
    • 77249113768 scopus 로고    scopus 로고
    • Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation
    • Breet NJ, van Werkum JW, Bouman HJ, et al. Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation. JAMA 2010;303:758-763.
    • (2010) JAMA , vol.303 , pp. 758-763
    • Breet, N.J.1    van Werkum, J.W.2    Bouman, H.J.3
  • 64
    • 33845948484 scopus 로고    scopus 로고
    • Platelet responsiveness to clopidogrel in patients with coronary syndrome. Comparison of platelet aggregation induced by ADP and flow cytometric analysis of intraplatelet VASP phosphorylation
    • Morel O, Viellard C, Faure A, et al. Platelet responsiveness to clopidogrel in patients with coronary syndrome. Comparison of platelet aggregation induced by ADP and flow cytometric analysis of intraplatelet VASP phosphorylation. Ann Cardiol Angeiol 2007;56:21-29.
    • (2007) Ann Cardiol Angeiol , vol.56 , pp. 21-29
    • Morel, O.1    Viellard, C.2    Faure, A.3
  • 65
    • 0038354521 scopus 로고    scopus 로고
    • Resistance to thienopyridines: Clinical detection of coronary Stent Thrombosis by monitoring of Vasodilator-Stimulated Phosphoprotein Phosphorylation
    • Barragan P, Bouvier JL, Roquebert PO, et al. Resistance to thienopyridines: Clinical detection of coronary Stent Thrombosis by monitoring of Vasodilator-Stimulated Phosphoprotein Phosphorylation. Catheter Cardiovasc Intev 2003;59:295-302.
    • (2003) Catheter Cardiovasc Intev , vol.59 , pp. 295-302
    • Barragan, P.1    Bouvier, J.L.2    Roquebert, P.O.3
  • 66
    • 2342489360 scopus 로고    scopus 로고
    • A novel modification of the thrombelastograph assay, isolating platelet function, correlates with optical aggregation
    • Craft RM, Chavez JJ, Bresee SJ, Wortham DC, Cohen E, Carroll RC. A novel modification of the thrombelastograph assay, isolating platelet function, correlates with optical aggregation. J Lab Clin Med 2004;143:301-309.
    • (2004) J Lab Clin Med , vol.143 , pp. 301-309
    • Craft, R.M.1    Chavez, J.J.2    Bresee, S.J.3    Wortham, D.C.4    Cohen, E.5    Carroll, R.C.6
  • 67
    • 33847254554 scopus 로고    scopus 로고
    • Delayed thrombin-induced platelet-fibrin clot generation by clopidogrel: A new dose-related effect demonstrated by thrombelastography in patients undergoing coronary artery stenting
    • Gurbel PA, Bliden KP, Guyer K, Aggarwal N, Tantry US. Delayed thrombin-induced platelet-fibrin clot generation by clopidogrel: A new dose-related effect demonstrated by thrombelastography in patients undergoing coronary artery stenting. Thromb Res 2007;119:563-570.
    • (2007) Thromb Res , vol.119 , pp. 563-570
    • Gurbel, P.A.1    Bliden, K.P.2    Guyer, K.3    Aggarwal, N.4    Tantry, U.S.5
  • 68
    • 84872287848 scopus 로고    scopus 로고
    • Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel (TRIGGER-PCI) Available from Accessed 18 August
    • Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel (TRIGGER-PCI) Available from: http://clinicaltrials.gov/ct2/show/NCT00910299 [Accessed 18 August 2010].
    • (2010)
  • 69
    • 77958573028 scopus 로고    scopus 로고
    • Clopidogrel loading dose adjustment according to platelet reactivity monitoring in patients carrying the 2C19 2* loss of function polymorphism
    • Bonello L, Armero S, Mokhtar OA, et al. Clopidogrel loading dose adjustment according to platelet reactivity monitoring in patients carrying the 2C19 2* loss of function polymorphism. J Am Coll Cardiol 2010;56:1630-1636.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 1630-1636
    • Bonello, L.1    Armero, S.2    Mokhtar, O.A.3
  • 70
    • 0030590746 scopus 로고    scopus 로고
    • A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)
    • CAPRIE Steering Committee.
    • CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet 1996;348:1329-1339.
    • (1996) Lancet , vol.348 , pp. 1329-1339
  • 71
    • 78049347838 scopus 로고    scopus 로고
    • New P2Y12 inhibitors versus clopidogrel in percutaneous coronary intervention: A meta-analysis
    • Bellemain-Appaix A, Brieger D, Beygui F, et al. New P2Y12 inhibitors versus clopidogrel in percutaneous coronary intervention: A meta-analysis. J Am Coll Cardiol 2010;56:1542-1551.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 1542-1551
    • Bellemain-Appaix, A.1    Brieger, D.2    Beygui, F.3
  • 72
    • 34347204130 scopus 로고    scopus 로고
    • Clinical evidence for anti-inflammatory effects of antiplatelet therapy in patients with atherothrombotic disease
    • Steinhubl SR, Badimon JJ, Bhatt DL, Herbert JM, Lüscher TF. Clinical evidence for anti-inflammatory effects of antiplatelet therapy in patients with atherothrombotic disease. Vasc Med 2007;12:113-122.
    • (2007) Vasc Med , vol.12 , pp. 113-122
    • Steinhubl, S.R.1    Badimon, J.J.2    Bhatt, D.L.3    Herbert, J.M.4    Lüscher, T.F.5
  • 75
    • 74249088972 scopus 로고    scopus 로고
    • Prasugrel compared with high-dose Clopidogrel in acute coronary syndrome. The randomized, double-blind ACAPULCO study
    • Montalescot G, Sideris G, Cohen R, et al. Prasugrel compared with high-dose Clopidogrel in acute coronary syndrome. The randomized, double-blind ACAPULCO study. Thromb Haemost 2010;103:213-223.
    • (2010) Thromb Haemost , vol.103 , pp. 213-223
    • Montalescot, G.1    Sideris, G.2    Cohen, R.3
  • 76
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • Wiviott SD, Braunwald E, McCabe CH, et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2007;357:2001-2015.
    • (2007) N Engl J Med , vol.357 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 77
    • 70149101223 scopus 로고    scopus 로고
    • Ticagrelor versus clopidogrel in patients with acute coronary syndromes
    • Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2009;361:1045-1057.
    • (2009) N Engl J Med , vol.361 , pp. 1045-1057
    • Wallentin, L.1    Becker, R.C.2    Budaj, A.3
  • 78
    • 71849119604 scopus 로고    scopus 로고
    • Intravenous platelet blockade with cangrelor during PCI
    • Bhatt DL, Lincoff AM, Gibson CM, et al. Intravenous platelet blockade with cangrelor during PCI. N Engl J Med 2009;361:2330-2341.
    • (2009) N Engl J Med , vol.361 , pp. 2330-2341
    • Bhatt, D.L.1    Lincoff, A.M.2    Gibson, C.M.3
  • 79
    • 84872293554 scopus 로고    scopus 로고
    • Bridge Study Maintenance of Platelet Inhibition With Cangrelor (Bridge) Available from Accessed 18 August
    • Bridge Study Maintenance of Platelet Inhibition With Cangrelor (Bridge) Available from: http://clinicaltrials.gov/ct2/show/NCT00767507 [Accessed 18 August 2010].
    • (2010)
  • 80
    • 77954510334 scopus 로고    scopus 로고
    • Elinogrel; Pharmacological principles; preclinical and early phase clinical testing
    • Veno M, Rao SV, Angiolillo DJ. Elinogrel; Pharmacological principles; preclinical and early phase clinical testing. Future Cardiol 2010;6:445-453.
    • (2010) Future Cardiol , vol.6 , pp. 445-453
    • Veno, M.1    Rao, S.V.2    Angiolillo, D.J.3
  • 81
    • 62549101321 scopus 로고    scopus 로고
    • Randomized comparison of adjunctive cilostazol versus high maintenance dose clopidogrel in patients with high post-treatment platelet reactivity: Results of the ACCEL-RESISTANCE (Adjunctive Cilostazol Versus High Maintenance Dose Clopidogrel in Patients With Clopidogrel Resistance) randomized study
    • Jeong YH, Lee SW, Choi BR, et al. Randomized comparison of adjunctive cilostazol versus high maintenance dose clopidogrel in patients with high post-treatment platelet reactivity: Results of the ACCEL-RESISTANCE (Adjunctive Cilostazol Versus High Maintenance Dose Clopidogrel in Patients With Clopidogrel Resistance) randomized study. J Am Coll Cardiol 2009;53:1101-1109.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1101-1109
    • Jeong, Y.H.1    Lee, S.W.2    Choi, B.R.3
  • 82
    • 34248227700 scopus 로고    scopus 로고
    • Incomplete stent apposition and very late stent thrombosis after drug-eluting stent implantation
    • Cook S, Wenaweser P, Togni M, et al. Incomplete stent apposition and very late stent thrombosis after drug-eluting stent implantation. Circulation 2007;115:2426-2434.
    • (2007) Circulation , vol.115 , pp. 2426-2434
    • Cook, S.1    Wenaweser, P.2    Togni, M.3
  • 83
    • 20144388922 scopus 로고    scopus 로고
    • Stent underexpansion and residual reference vessel stenosis are associated with stent thrombosis after successful sirlimus-eluting stent implantation
    • Fujii K, Carlier S, Mintz G, et al. Stent underexpansion and residual reference vessel stenosis are associated with stent thrombosis after successful sirlimus-eluting stent implantation. J Am Coll Cardiol 2005;45:995-998.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 995-998
    • Fujii, K.1    Carlier, S.2    Mintz, G.3
  • 84
    • 0032147104 scopus 로고    scopus 로고
    • Intravascular ultrasound-guided optimized stent deployment. Immediate and 6 months clinical and angiographic results from the Multicenter Ultrasound Stenting in Coronaries Study (MUSIC Study)
    • de Jaegere P, Mudra H, Figulla H, et al. Intravascular ultrasound-guided optimized stent deployment. Immediate and 6 months clinical and angiographic results from the Multicenter Ultrasound Stenting in Coronaries Study (MUSIC Study). Eur Heart J 1998;19:1214-1223.
    • (1998) Eur Heart J , vol.19 , pp. 1214-1223
    • de Jaegere, P.1    Mudra, H.2    Figulla, H.3
  • 85
    • 21044445480 scopus 로고    scopus 로고
    • Endothelial progenitor cell capture by stents coated with antibody against CD34
    • Aoki J, Serruys PW, van Beusekom H, et al. Endothelial progenitor cell capture by stents coated with antibody against CD34. J Am Coll Cardiol 2005;45:1574-1579.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1574-1579
    • Aoki, J.1    Serruys, P.W.2    van Beusekom, H.3
  • 86
    • 64549133799 scopus 로고    scopus 로고
    • Evaluation of individualized clopidogrel therapy after drug-eluting stent implantation in patients with high residual platelet reactivity: Design and rationale of the GRAVITAS trial
    • Price MJ, Berger PB, Angiolillo DJ, et al. Evaluation of individualized clopidogrel therapy after drug-eluting stent implantation in patients with high residual platelet reactivity: Design and rationale of the GRAVITAS trial. Am Heart J 2009;157:818-824.
    • (2009) Am Heart J , vol.157 , pp. 818-824
    • Price, M.J.1    Berger, P.B.2    Angiolillo, D.J.3
  • 87
    • 35048886977 scopus 로고    scopus 로고
    • Blood platelet count and 30-day clinical outcomes after percutaneous coronary intervention. Pooled analysis of four ISAR trials
    • Iijima R, Ndrepepa G, Mehilli J, Bruskina O, Schulz S, Schomig A, Kastrati A. Blood platelet count and 30-day clinical outcomes after percutaneous coronary intervention. Pooled analysis of four ISAR trials. Thromb Haemost 2007;98:852-857.
    • (2007) Thromb Haemost , vol.98 , pp. 852-857
    • Iijima, R.1    Ndrepepa, G.2    Mehilli, J.3    Bruskina, O.4    Schulz, S.5    Schomig, A.6    Kastrati, A.7
  • 88
    • 0038649988 scopus 로고    scopus 로고
    • Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity
    • Gurbel PA, Bliden KP, Hiatt BL, O'Connor CM. Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation 2003;107:2908-2913.
    • (2003) Circulation , vol.107 , pp. 2908-2913
    • Gurbel, P.A.1    Bliden, K.P.2    Hiatt, B.L.3    O'Connor, C.M.4
  • 89
    • 33847130538 scopus 로고    scopus 로고
    • Antiplatelet Therapy in Diabetes Mellitus (OPTIMUS) Study With Diabetes Mellitus and Coronary Artery Disease: Results of the Optimizing Randomized Comparison of a High Clopidogrel Maintenance Dose in Patients
    • Angiolillo DJ, Shoemaker SB, Desai B, et al. Antiplatelet Therapy in Diabetes Mellitus (OPTIMUS) Study With Diabetes Mellitus and Coronary Artery Disease: Results of the Optimizing Randomized Comparison of a High Clopidogrel Maintenance Dose in Patients. Circulation 2007;115;708-716.
    • (2007) Circulation , vol.115 , pp. 708-716
    • Angiolillo, D.J.1    Shoemaker, S.B.2    Desai, B.3
  • 90
    • 84872310367 scopus 로고    scopus 로고
    • TA182 Acute coronary syndrome - prasugrel: Guidance. Available from Accessed 24 August
    • TA182 Acute coronary syndrome - prasugrel: Guidance. Available from: http://guidance.nice.org.uk/TA182/Guidance/pdf/English [Accessed 24 August 2010].
    • (2010)
  • 91
    • 27144475755 scopus 로고    scopus 로고
    • Impact of bleeding severity on clinical outcome among patients with acute coronary syndromes
    • Rao SV, O'Grady K, Pieper KS, et al. Impact of bleeding severity on clinical outcome among patients with acute coronary syndromes. Am J Cardiol 2005;96:1200-1206.
    • (2005) Am J Cardiol , vol.96 , pp. 1200-1206
    • Rao, S.V.1    O'Grady, K.2    Pieper, K.S.3
  • 92
    • 35348913868 scopus 로고    scopus 로고
    • Predictors and impact of major haemorrhage on mortality following percutaneous coronary intervention from the REPLACE-2 trial
    • Feit F, Voeltz MD, Attubato MJ, et al. Predictors and impact of major haemorrhage on mortality following percutaneous coronary intervention from the REPLACE-2 trial. Am J Cardiol 2007;100:1364-1369.
    • (2007) Am J Cardiol , vol.100 , pp. 1364-1369
    • Feit, F.1    Voeltz, M.D.2    Attubato, M.J.3
  • 93
    • 84872292630 scopus 로고    scopus 로고
    • Thrombocyte Activity Reassessment and GEnoTyping for PCI (TARGET-PCI). Available from:Accessed 15 March
    • Thrombocyte Activity Reassessment and GEnoTyping for PCI (TARGET-PCI). Available from: http://www.clinicaltrials.gov/ct2/show/NCT01177592?term=TARGETPCI&rank=1 [Accessed 15 March 2011].
    • (2011)
  • 94
    • 84872359975 scopus 로고    scopus 로고
    • A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects (TRILOGY ACS). Available from:Accessed 23 March
    • A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects (TRILOGY ACS). Available from: http://clinicaltrials.gov/ct2/show/NCT00699998 [Accessed 23 March 2011].
    • (2011)
  • 95
    • 84872321273 scopus 로고    scopus 로고
    • Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin (PEGASUS) Available from:Accessed 23 March
    • Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin (PEGASUS) Available from: http://clinicaltrials.gov/ct2/show/NCT01225562?term=PEGASUS&rank=1 [Accessed 23 March 2011].
    • (2011)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.