Clinical significance of fibroblast-specific protein-1 expression on podocytes in patients with focal segmental glomerulosclerosis

Nephron - Clinical Practice

Volumn 120, Issue 1, 2012, Pages

  Samejima, Ken Ichi ^a   Nakatani, Kimihiko ^a   Suzuki, Daisuke ^b   Asai, Osamu ^a   Sakan, Hirokazu ^a   Yoshimoto, Shuhei ^a   Yamaguchi, Yukinari ^a   Matsui, Masaru ^a   Akai, Yasuhiro ^a   Toyoda, Masao ^b   Iwano, Masayuki ^a,c   Saito, Yoshihiko ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b TOKAI UNIVERSITY   (Japan)

^c UNIVERSITY OF FUKUI   (Japan)

Author keywords

Fibroblast specific protein 1; Focal segmental glomerulosclerosis; Podocyte

Indexed keywords

CALVASCULIN; COLLAGEN TYPE 1; MESSENGER RNA;

ADULT; AGED; ARTICLE; CELL COUNT; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS-SECTIONAL STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; FOCAL GLOMERULOSCLEROSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; LASER CAPTURE MICRODISSECTION; MAJOR CLINICAL STUDY; MALE; MINIMAL CHANGE GLOMERULONEPHRITIS; PATHOPHYSIOLOGY; PODOCYTE; PREVALENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; TISSUE SECTION;

ADOLESCENT; ADULT; AGED; BIOLOGICAL MARKERS; BIOPSY; CALCIUM-BINDING PROTEINS; CELL ADHESION; CELL COUNT; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HUMANS; KIDNEY GLOMERULUS; MALE; MIDDLE AGED; NEPHRITIS, INTERSTITIAL; NEPHROSIS, LIPOID; PODOCYTES; RNA, MESSENGER; YOUNG ADULT;

EID: 84858397781     PISSN: None     EISSN: 16602110     Source Type: Journal    
DOI: 10.1159/000334184     Document Type: Article

References (28)

1. Nolasco F, Cameron JS, Heywood EF, Hicks J, Ogg C, Williams DG: Adult-onset minimal change nephrotic syndrome: a longterm follow-up. Kidney Int 1986; 29: 1215-1223. (Pubitemid 16094236)
2. Tune BM, Mendoza SA: Treatment of the idiopathic nephrotic syndrome: regimens and outcomes in children and adults. J Am Soc Nephrol 1997; 8: 824-832. (Pubitemid 27493599)
3. Narasimhan B, Chacko B, John GT, Korula A, Kirubakaran MG, Jacob CK: Characterization of kidney lesions in Indian adults: towards a renal biopsy registry. J Nephrol 2006; 19: 205-210. (Pubitemid 44420113)
4. Nolasco F, Cameron JS, Hicks J, Ogg CS, Williams DG: Adult-onset nephrotic syndrome with minimal changes: response to corticosteroids and cyclophosphamide. Proc Eur Dial Transplant Assoc Eur Ren Assoc 1985; 21: 588-593.
5. Haas M, Spargo BH, Coventry S: Increasing incidence of focal-segmental glomerulosclerosis among adult nephropathies: a 20-year renal biopsy study. Am J Kidney Dis 1995; 26: 740-750.
6. Ponticelli C, Villa M, Banfi G, Cesana B, Pozzi C, Pani A, Passerini P, Farina M, Grassi C, Baroli A: Can prolonged treatment improve the prognosis in adults with focal segmental glomerulosclerosis? Am J Kidney Dis 1999 34 618-625. (Pubitemid 29473046)
7. Rydel JJ, Korbet SM, Borok RZ, Schwartz MM: Focal segmental glomerular sclerosis in adults: presentation, course, and response to treatment. Am J Kidney Dis 1995; 25: 534-542.
8. Cohen AH, Mampaso F, Zamboni L: Glomerular podocyte degeneration in human renal disease: an ultrastructural study. Lab Invest 1977; 37: 30-42. (Pubitemid 8145772)
9. Grishman E, Churg J: Focal glomerular sclerosis in nephrotic patients: an electron microscopic study of glomerular podocytes. Kidney Int 1975; 7: 111-122.
10. Kriz W, Elger M, Nagata M, Kretzler M, Uiker S, Koeppen-Hageman I, Tenschert S, Lemley KV: The role of podocytes in the development of glomerular sclerosis. Kidney Int Suppl 1994; 45:S64-S72.
11. Hara M, Yanagihara T, Kihara I: Urinary podocytes in primary focal segmental glomerulosclerosis. Nephron 2001; 89: 342-347. (Pubitemid 34701770)
12. Matsusaka T, Xin J, Niwa S, Kobayashi K, Akatsuka A, Hashizume H, Wang QC, Pastan I, Fogo AB, Ichikawa I: Genetic engineering of glomerular sclerosis in the mouse via control of onset and severity of podocytespecific injury. J Am Soc Nephrol 2005; 16: 1013-1023. (Pubitemid 41710312)
13. Wharram BL, Goyal M, Wiggins JE, Sanden SK, Hussain S, Filipiak WE, Saunders TL, Dysko RC, Kohno K, Holzman LB, Wiggins RC: Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene. J Am Soc Nephrol 2005; 16: 2941-2952. (Pubitemid 44743492)
14. Regele HM, Fillipovic E, Langer B, Poczewki H, Kraxberger I, Bittner RE, Kerjaschki D: Glomerular expression of dystroglycans is reduced in minimal change nephrosis but not in focal segmental glomerulosclerosis. J Am Soc Nephrol 2000; 11: 403-412. (Pubitemid 30115070)
15. Schmid H, Henger A, Cohen CD, Frach K, Grone HJ, Schlondorff D, Kretzler M: Gene expression profiles of podocyte-associated molecules as diagnostic markers in acquired proteinuric diseases. J Am Soc Nephrol 2003; 14: 2958-2966. (Pubitemid 37305659)
16. Iwano M, Plieth D, Danoff TM, Xue C, Okada H, Neilson EG: Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 2002; 110: 341-350. (Pubitemid 34847966)
17. Okada H, Danoff TM, Kalluri R, Neilson EG: Early role of Fsp1 in epithelial-mesenchymal transformation. Am J Physiol 1997; 273: F563-F574.
18. Li Y, Kang YS, Dai C, Kiss LP, Wen X, Liu Y: Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria. Am J Pathol 2008; 172: 299-308. (Pubitemid 351282018)
19. Yamaguchi Y, Iwano M, Suzuki D, Nakatani K, Kimura K, Harada K, Kubo A, Akai Y, Toyoda M, Kanauchi M, Neilson EG, Saito Y: Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy. Am J Kidney Dis 2009; 54: 653-664.
20. Imai E, Horio M, Nitta K, Yamagata K, Iseki K, Tsukamoto Y, Ito S, Makino H, Hishida A, Matsuo S: Modification of the modification of diet in renal disease (MDRD) study equation for Japan. Am J Kidney Dis 2007; 50: 927-937. (Pubitemid 350130278)
21. Nishitani Y, Iwano M, Yamaguchi Y, Harada K, Nakatani K, Akai Y, Nishino T, Shiiki H, Kanauchi M, Saito Y, Neilson EG: Fibroblastspecific protein 1 is a specific prognostic marker for renal survival in patients with IgAN. Kidney Int 2005; 68: 1078-1085. (Pubitemid 43246424)
22. Suzuki D, Miyazaki M, Naka R, Koji T, Yagame M, Jinde K, Endoh M, Nomoto Y, Sakai H: In situ hybridization of interleukin 6 in diabetic nephropathy. Diabetes 1995; 44: 1233-1238.
23. Yoshimoto S, Nakatani K, Iwano M, Asai O, Samejima K, Sakan H, Terada M, Harada K, Akai Y, Shiiki H, Nose M, Saito Y: Elevated levels of fractalkine expression and accumulation of CD16+ monocytes in glomeruli of active lupus nephritis. Am J Kidney Dis 2007; 50: 47-58. (Pubitemid 46970800)
24. Shi SF, Wang SX, Zhang YK, Zhao MH, Zou WZ: Ultrastructural features and expression of cytoskeleton proteins of podocyte from patients with minimal change disease and focal segmental glomerulosclerosis. Ren Fail 2008; 30: 477-483.
25. Noel LH: Morphological features of primary focal and segmental glomerulosclerosis. Nephrol Dial Transplant 1999; 14(suppl 3):53-57. (Pubitemid 29241713)
26. Bariety J, Nochy D, Mandet C, Jacquot C, Glotz D, Meyrier A: Podocytes undergo phenotypic changes and express macrophagicassociated markers in idiopathic collapsing glomerulopathy. Kidney Int 1998; 53: 918-925. (Pubitemid 28155664)
27. Bariety J, Bruneval P, Hill G, Irinopoulou T, Mandet C, Meyrier A: Posttransplantation relapse of FSGS is characterized by glomerular epithelial cell transdifferentiation. J Am Soc Nephrol 2001; 12: 261-274. (Pubitemid 32116368)
28. Nishimoto K, Shiiki H, Nishino T, Uyama H, Iwano M, Dohi K: Reversible glomerular hypertrophy in adult patients with primary focal segmental glomerulosclerosis. J Am Soc Nephrol 1997; 8: 1668-1678.