Impaired spontaneous thrombolytic activity measured by global thrombosis test in males with metabolic syndrome

Thrombosis Research

Volumn 129, Issue 4, 2012, Pages 499-501

  Suehiro, Akira ^a   Wakabayashi, Ichiro ^a   Uchida, Kagehiro ^b   Yamashita, Tsutomu ^c   Yamamoto, Junichiro ^c  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b Biomarker Science Co Ltd   (Japan)

^c KOBE GAKUIN UNIVERSITY   (Japan)

Author keywords

Global thrombosis test (GTT); Metabolic syndrome; PAI 1; Thrombolytic activity

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRIACYLGLYCEROL;

ADULT; ARTICLE; BLEEDING TIME; BLOOD CLOT LYSIS; BLOOD CLOTTING; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FIBRINOLYSIS; GLOBAL THROMBOSIS TEST; HUMAN; IN VITRO STUDY; MALE; METABOLIC SYNDROME X; PRIORITY JOURNAL; SCREENING TEST; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE FUNCTION; THROMBOSIS; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE;

ADULT; COMORBIDITY; HUMANS; JAPAN; MALE; METABOLIC SYNDROME X; PLATELET FUNCTION TESTS; PREVALENCE; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; RISK FACTORS; SENSITIVITY AND SPECIFICITY; THROMBOSIS;

EID: 84858340907     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.06.019     Document Type: Article

References (15)

1. I. Palnomo, H. Moore-Carrasco, M. Alarcon, A. Rojas, F. Espana, and V. Andres Pathophysiology of the proatherothrombotic state in the metabolic syndrome Front Biosci (Schol Ed) 2 2010 194 208
2. M. Nieuwdorp, E.S. Stroes, J.C. Meijers, and H. Büller Hypercoagulability in the metabolic syndrome Curr Opin Pharmacol 5 2005 155 159
3. M.C. Alessi, and I. Juhan-Vague Metabolic syndrome, haemostasis and thrombosis Thromb Haemost 99 2008 995 1000
4. G.P. Van Guilder, G.I. Hoetzer, J.J. Greiner, B.I. Stauffer, and C.A. DeSouza Metabolic syndrome and endothelial fibrinolytic capacity in obese adults Am J Physiol Regul Integr Comp Physiol 294 2008 2007
5. J. Yamamoto, T. Yamashita, H. Ikarugi, T. Taka, M. Hashimoto, and H. Ishii Gorog thrombosis test: a global in-vitro test of platelet function and thrombolysis Blood Coagul Fibrin 14 2003 31 39
6. D.A. Gorog, J. Yamamoto, S. Saraf, H. Ishii, Y. Ijiri, and H. Ikarugi First direct comparison of platelet reactivity and thrombolytic status between Japanese and Western volunteers: Possible relationship to the "Japanese paradox" Int J Cardiol 2010 (Electronic publication ahead of print) doi: 10.1016/j.ijcard.2010.07.002.
7. P. Zimmet, D. Magliano, Y. Matsuzawa, G. Alberti, and J. Shaw The metabolic syndrome: A global public health problem and a new definition J Atheroscler Thromb 12 2005 295 300
8. A. Hanna-Moussa, M.J. Gardner, L.R. Kurukulasuriya, and J.R. Sowers Dysglycemia/prediabetes and cardiovascular risk factors Rev Cardiovasc 10 2009 202 208
9. I.T. Lee, W.J. Lee, H.C. Ou, C.N. Huang, and W.H. Sheu Metabolic syndrome abating the beneficial effect of pravastatin treatment on adhesion of endothelium by monocytes in subjects with hypercholesterolemia Metabolism 58 2009 416 420
10. G. Kang, L. Guo, Z. Guo, X. Ho, Z. Zhou, and H. Zhou Impact of blood pressure and other components of the metabolic syndrome on the development of cardiovascular diseas Circul J 74 2010 456 461
11. B. Gustafson Adipose tissue, inflammation and atherosclerosis J Atheroscler Thromb 17 2010 332 341
12. A.G. Goodwill, M.E. James, and J.C. Frisbee Increased vascular thromboxane generation impairs dilation of skeletal muscle arterioles of obese Zucker rats with reduced oxygen tension Am J Physiol Heart Circ Physiol 295 2008 H1522 H15288
13. M.E. Meltzer, C.J. Doggen, P.G. de Groot, F.R. Rosendaal, and T. Lisman The impact of the fibrinolytic system on the risk of venous and arterial thrombosis Semin Thromb Hemost 35 2009 468 477
14. J. Yamamoto, A. Naemura, Y. Ijiri, K. Ogawa, T. Suzuki, and Y. Shimada The antithrombotic effects of carrot filtrates in rats and mice Blood Coagul Fibrin 19 2008 785 792
15. R.P. Donahue, K. Rejman, L.B. Rafalson, J. Dmochowski, S. Stranges, and M. Trevisan Sex differences in endothelial function markers before conversion to pre-diabetes: does the clock start ticking earlier among women? The Western New York Study Diabetes Care 30 2007 354 359