Interleukin-10 promoter microsatellite polymorphisms influence the immune response to heparin and the risk of heparin-induced thrombocytopenia

Thrombosis Research

Volumn 129, Issue 4, 2012, Pages 465-469

  Pouplard, Claire ^a   Cornillet Lefebvre, Pascale ^c,d   Attaoua, Redha ^e   Leroux, Dorothée ^a   Lecocq Lafon, Carinne ^c,d   Rollin, Jérôme ^a,b   Grigorescu, Florin ^e   Nguyen, Philippe ^c,d   Gruel, Yves ^a,b  

^a SERVICE DE DERMATOLOGIE   (France)

^b UNIVERSITÉ DE TOURS   (France)

^c University Hospital of Reims   (France)

^d UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^e UNIV MONTPELLIER   (France)

Author keywords

gene polymorphisms; heparin; IL10; thrombocytopenia

Indexed keywords

GENOMIC DNA; HEPARIN; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 10; LOW MOLECULAR WEIGHT HEPARIN; THROMBOCYTE FACTOR 4;

ADULT; AGED; AMPLIFIED FRAGMENT LENGTH POLYMORPHISM; ARTICLE; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; DNA EXTRACTION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; HAPLOTYPE; HEPARIN INDUCED THROMBOCYTOPENIA; HUMAN; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MICROSATELLITE MARKER; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; THROMBOCYTE COUNT; THROMBOCYTOPENIA; TREATMENT DURATION;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; FRANCE; HEPARIN; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-10; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PREVALENCE; PROMOTER REGIONS, GENETIC; RISK ASSESSMENT; RISK FACTORS; THROMBOCYTOPENIA;

EID: 84858338630     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.09.033     Document Type: Article

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