PDK1 regulates the generation of oligodendrocyte precursor cells at an early stage of mouse telencephalic development

Genes to Cells

Volumn 17, Issue 4, 2012, Pages 326-335

  Watatani, Kenji ^a   Hirabayashi, Yusuke ^a   Itoh, Yasuhiro ^a   Gotoh, Yukiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; TRANSCRIPTION FACTOR SOX10;

ARTICLE; BRAIN DEVELOPMENT; CORPUS STRIATUM; DEVELOPMENTAL STAGE; EMBRYO; EMBRYO DEVELOPMENT; GENE DELETION; MOUSE; NEOCORTEX; NERVE CELL; NEURAL PRECURSOR CELL; NONHUMAN; OLIGODENDROGLIA; PHYSIOLOGY; PRIORITY JOURNAL; TELENCEPHALON;

ANIMALS; CELL DIFFERENTIATION; FIBROBLAST GROWTH FACTOR 2; MICE; NEURAL STEM CELLS; OLIGODENDROGLIA; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN-SERINE-THREONINE KINASES; TELENCEPHALON;

EID: 84858338391     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2012.01591.x     Document Type: Article

References (40)

1. Abematsu, M., Kagawa, T., Fukuda, S., Inoue, T., Takebayashi, H., Komiya, S. & Taga, T. (2006) Basic fibroblast growth factor endows dorsal telencephalic neural progenitors with the ability to differentiate into oligodendrocytes but not gamma-aminobutyric acidergic neurons. J. Neurosci. Res. 83, 731-743.
2. Alberta, J.A., Park, S.K., Mora, J., Yuk, D., Pawlitzky, I., Iannarelli, P., Vartanian, T., Stiles, C.D. & Rowitch, D.H. (2001) Sonic hedgehog is required during an early phase of oligodendrocyte development in mammalian brain. Mol. Cell. Neurosci. 18, 434-441.
3. Arai, K. & Lo, E.H. (2009) An oligovascular niche: cerebral endothelial cells promote the survival and proliferation of oligodendrocyte precursor cells. J. Neurosci. 29, 4351-4355.
4. Battiste, J., Helms, A.W., Kim, E.J., Savage, T.K., Lagace, D.C., Mandyam, C.D., Eisch, A.J., Miyoshi, G. & Johnson, J.E. (2007) Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development 134, 285-293.
5. Bibollet-Bahena, O. & Almazan, G. (2009) IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways. J. Neurochem. 109, 1440-1451.
6. Bilican, B., Fiore-Heriche, C., Compston, A., Allen, N.D. & Chandran, S. (2008) Induction of Olig2 precursors by FGF involves BMP signalling blockade at the Smad level. PLoS ONE 3, e2863.
7. Cha, T.L., Zhou, B.P., Xia, W., Wu, Y., Yang, C.C., Chen, C.T., Ping, B., Otte, A.P. & Hung, M.C. (2005) Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3. Science 310, 306-310.
8. Chandran, S., Kato, H., Gerreli, D., Compston, A., Svendsen, C.N. & Allen, N.D. (2003) FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway. Development 130, 6599-6609.
9. Chandran, S., Svendsen, C., Compston, A. & Scolding, N. (1998) Regional potential for oligodendrocyte generation in the rodent embryonic spinal cord following exposure to EGF and FGF-2. Glia, 24, 382-389.
10. Cui, Q.L. & Almazan, G. (2007) IGF-I-induced oligodendrocyte progenitor proliferation requires PI3K/Akt, MEK/ERK, and Src-like tyrosine kinases. J. Neurochem. 100, 1480-1493.
11. Emery, B. (2010) Transcriptional and post-transcriptional control of CNS myelination. Curr. Opin. Neurobiol. 20, 601-607.
12. Finzsch, M., Stolt, C.C., Lommes, P. & Wegner, M. (2008) Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression. Development 135, 637-646.
13. Flores, A.I., Mallon, B.S., Matsui, T., Ogawa, W., Rosenzweig, A., Okamoto, T. & Macklin, W.B. (2000) Akt-mediated survival of oligodendrocytes induced by neuregulins. J. Neurosci. 20, 7622-7630.
14. Flores, A.I., Narayanan, S.P., Morse, E.N., Shick, H.E., Yin, X., Kidd, G., Avila, R.L., Kirschner, D.A. & Macklin, W.B. (2008) Constitutively active Akt induces enhanced myelination in the CNS. J. Neurosci. 28, 7174-7183.
15. Fortin, D., Rom, E., Sun, H., Yayon, A. & Bansal, R. (2005) Distinct fibroblast growth factor (FGF)/FGF receptor signaling pairs initiate diverse cellular responses in the oligodendrocyte lineage. J. Neurosci. 25, 7470-7479.
16. Furusho, M., Kaga, Y., Ishii, A., Hebert, J.M. & Bansal, R. (2011) Fibroblast growth factor signaling is required for the generation of oligodendrocyte progenitors from the embryonic forebrain. J. Neurosci. 31, 5055-5066.
17. Gabay, L., Lowell, S., Rubin, L.L. & Anderson, D.J. (2003) Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro. Neuron 40, 485-499.
18. Guillemot, F. (2007) Cell fate specification in the mammalian telencephalon. Prog. Neurobiol. 83, 37-52.
19. Hu, X., Jin, L. & Feng, L. (2004) Erk1/2 but not PI3K pathway is required for neurotrophin 3-induced oligodendrocyte differentiation of post-natal neural stem cells. J. Neurochem. 90, 1339-1347.
20. Kessaris, N., Fogarty, M., Iannarelli, P., Grist, M., Wegner, M. & Richardson, W.D. (2006) Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage. Nat. Neurosci. 9, 173-179.
21. Kessaris, N., Jamen, F., Rubin, L.L. & Richardson, W.D. (2004) Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors. Development 131, 1289-1298.
22. Liu, X., Li, Y., Zhang, Y., Lu, Y., Guo, W., Liu, P., Zhou, J., Xiang, Z. & He, C. (2011) SHP-2 promotes the maturation of oligodendrocyte precursor cells through Akt and ERK1/2 signaling in vitro. PLoS ONE 6, e21058.
23. Lu, Q.R., Cai, L., Rowitch, D., Cepko, C.L. & Stiles, C.D. (2001) Ectopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex. Nat. Neurosci. 4, 973-974.
24. Narayanan, S.P., Flores, A.I., Wang, F. & Macklin, W.B. (2009) Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination. J. Neurosci. 29, 6860-6870.
25. Naruse, M., Nakahira, E., Miyata, T., Hitoshi, S., Ikenaka, K. & Bansal, R. (2006) Induction of oligodendrocyte progenitors in dorsal forebrain by intraventricular microinjection of FGF-2. Dev. Biol. 297, 262-273.
26. Nery, S., Wichterle, H. & Fishell, G. (2001) Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain. Development 128, 527-540.
27. Oishi, K., Watatani, K., Itoh, Y., Okano, H., Guillemot, F., Nakajima, K. & Gotoh, Y. (2009) Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1. Proc. Natl Acad. Sci. USA 106, 13064-13069.
28. Ono, K., Takebayashi, H., Ikeda, K., Furusho, M., Nishizawa, T., Watanabe, K. & Ikenaka, K. (2008) Regional- and temporal-dependent changes in the differentiation of Olig2 progenitors in the forebrain, and the impact on astrocyte development in the dorsal pallium. Dev. Biol. 320, 456-468.
29. Parras, C.M., Hunt, C., Sugimori, M., Nakafuku, M., Rowitch, D. & Guillemot, F. (2007) The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes. J. Neurosci. 27, 4233-4242.
30. Qi, Y., Cai, J., Wu, Y., Wu, R., Lee, J., Fu, H., Rao, M., Sussel, L., Rubenstein, J. & Qiu, M. (2001) Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor. Development 128, 2723-2733.
31. Rowitch, D.H. & Kriegstein, A.R. (2010) Developmental genetics of vertebrate glial-cell specification. Nature 468, 214-222.
32. Setoguchi, T. & Kondo, T. (2004) Nuclear export of OLIG2 in neural stem cells is essential for ciliary neurotrophic factor-induced astrocyte differentiation. J. Cell Biol. 166, 963-968.
33. Sher, F., Rossler, R., Brouwer, N., Balasubramaniyan, V., Boddeke, E. & Copray, S. (2008) Differentiation of neural stem cells into oligodendrocytes: involvement of the polycomb group protein Ezh2. Stem Cells 26, 2875-2883.
34. Stolt, C.C., Lommes, P., Sock, E., Chaboissier, M.C., Schedl, A. & Wegner, M. (2003) The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 17, 1677-1689.
35. Stolt, C.C., Rehberg, S., Ader, M., Lommes, P., Riethmacher, D., Schachner, M., Bartsch, U. & Wegner, M. (2002) Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev. 16, 165-170.
36. Sugimori, M., Nagao, M., Parras, C.M., Nakatani, H., Lebel, M., Guillemot, F. & Nakafuku, M. (2008) Ascl1 is required for oligodendrocyte development in the spinal cord. Development 135, 1271-1281.
37. Takebayashi, H., Nabeshima, Y., Yoshida, S., Chisaka, O. & Ikenaka, K. (2002) The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages. Curr. Biol. 12, 1157-1163.
38. Tekki-Kessaris, N., Woodruff, R., Hall, A.C., Gaffield, W., Kimura, S., Stiles, C.D., Rowitch, D.H. & Richardson, W.D. (2001) Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon. Development 128, 2545-2554.
39. Zhou, Q., Choi, G. & Anderson, D.J. (2001) The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2. Neuron 31, 791-807.
40. Zhou, Q., Wang, S. & Anderson, D.J. (2000) Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors. Neuron 25, 331-343.