메뉴 건너뛰기




Volumn 129, Issue 4, 2012, Pages

The role of thrombin receptors PAR1 and PAR4 for PAI-1 storage, synthesis and secretion by human platelets

Author keywords

Blood Platelets; PAR1; PAR4; Plasminogen Activator Inhibitor 1; Thrombin; VEGF

Indexed keywords

ENDOSTATIN; MESSENGER RNA; PADGEM PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 4; THROMBIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE; VASCULOTROPIN;

EID: 84858333888     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.12.021     Document Type: Article
Times cited : (23)

References (46)
  • 1
    • 0028179510 scopus 로고
    • G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets
    • S. Offermanns, K.L. Laugwitz, K. Spicher, and G. Schultz G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets Proc Natl Acad Sci U S A 91 1994 504 508
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 504-508
    • Offermanns, S.1    Laugwitz, K.L.2    Spicher, K.3    Schultz, G.4
  • 2
    • 11844276647 scopus 로고    scopus 로고
    • Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets
    • L. Ma, R. Perini, W. McKnight, M. Dicay, A. Klein, and M.D. Hollenberg Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets Proc Natl Acad Sci U S A 102 2005 216 220
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 216-220
    • Ma, L.1    Perini, R.2    McKnight, W.3    Dicay, M.4    Klein, A.5    Hollenberg, M.D.6
  • 3
    • 67849103774 scopus 로고    scopus 로고
    • Selective sorting of alpha-granule proteins
    • J.E. Italiano Jr., and E.M. Battinelli Selective sorting of alpha-granule proteins J Thromb Haemost 7 Suppl 1 2009 173 176
    • (2009) J Thromb Haemost , vol.7 , Issue.SUPPL. 1 , pp. 173-176
    • Italiano, Jr.J.E.1    Battinelli, E.M.2
  • 4
    • 49649107246 scopus 로고    scopus 로고
    • The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine
    • M. Grenegard, K. Vretenbrant-Oberg, M. Nylander, S. Desilets, E.G. Lindstrom, and A. Larsson The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine J Biol Chem 283 2008 18493 18504
    • (2008) J Biol Chem , vol.283 , pp. 18493-18504
    • Grenegard, M.1    Vretenbrant-Oberg, K.2    Nylander, M.3    Desilets, S.4    Lindstrom, E.G.5    Larsson, A.6
  • 5
    • 79956052911 scopus 로고    scopus 로고
    • Protease-activated receptor 1 (PAR1) signalling desensitization is counteracted via PAR4 signalling in human platelets
    • K. Falker, L. Haglund, P. Gunnarsson, M. Nylander, T.L. Lindahl, and M. Grenegard Protease-activated receptor 1 (PAR1) signalling desensitization is counteracted via PAR4 signalling in human platelets Biochem J 436 2011 469 480
    • (2011) Biochem J , vol.436 , pp. 469-480
    • Falker, K.1    Haglund, L.2    Gunnarsson, P.3    Nylander, M.4    Lindahl, T.L.5    Grenegard, M.6
  • 6
    • 33947308600 scopus 로고    scopus 로고
    • Platelet activation via PAR4 is involved in the initiation of thrombin generation and in clot elasticity development
    • K. Vretenbrant, S. Ramstrom, M. Bjerke, and T.L. Lindahl Platelet activation via PAR4 is involved in the initiation of thrombin generation and in clot elasticity development Thromb Haemost 97 2007 417 424
    • (2007) Thromb Haemost , vol.97 , pp. 417-424
    • Vretenbrant, K.1    Ramstrom, S.2    Bjerke, M.3    Lindahl, T.L.4
  • 7
    • 0036213048 scopus 로고    scopus 로고
    • Role of the PAR4 thrombin receptor in stabilizing platelet-platelet aggregates as revealed by a patient with Hermansky-Pudlak syndrome
    • L. Covic, C. Singh, H. Smith, and A. Kuliopulos Role of the PAR4 thrombin receptor in stabilizing platelet-platelet aggregates as revealed by a patient with Hermansky-Pudlak syndrome Thromb Haemost 87 2002 722 727
    • (2002) Thromb Haemost , vol.87 , pp. 722-727
    • Covic, L.1    Singh, C.2    Smith, H.3    Kuliopulos, A.4
  • 8
    • 33847116251 scopus 로고    scopus 로고
    • Protease-activated receptors differentially regulate human platelet activation through a phosphatidic acid-dependent pathway
    • M. Holinstat, B. Voss, M.L. Bilodeau, and H.E. Hamm Protease-activated receptors differentially regulate human platelet activation through a phosphatidic acid-dependent pathway Mol Pharmacol 71 2007 686 694
    • (2007) Mol Pharmacol , vol.71 , pp. 686-694
    • Holinstat, M.1    Voss, B.2    Bilodeau, M.L.3    Hamm, H.E.4
  • 9
    • 34247133061 scopus 로고    scopus 로고
    • Protease-activating receptor-4 induces full platelet spreading on a fibrinogen matrix: Involvement of ERK2 and p38 and Ca2 + mobilization
    • A. Mazharian, S. Roger, E. Berrou, F. Adam, A. Kauskot, and P. Nurden Protease-activating receptor-4 induces full platelet spreading on a fibrinogen matrix: involvement of ERK2 and p38 and Ca2 + mobilization J Biol Chem 282 2007 5478 5487
    • (2007) J Biol Chem , vol.282 , pp. 5478-5487
    • Mazharian, A.1    Roger, S.2    Berrou, E.3    Adam, F.4    Kauskot, A.5    Nurden, P.6
  • 10
    • 40349085619 scopus 로고    scopus 로고
    • Proteinases and signalling: Pathophysiological and therapeutic implications via PARs and more
    • R. Ramachandran, and M.D. Hollenberg Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more Br J Pharmacol 153 Suppl 1 2008 S263 S282
    • (2008) Br J Pharmacol , vol.153 , Issue.SUPPL. 1
    • Ramachandran, R.1    Hollenberg, M.D.2
  • 11
    • 0030039610 scopus 로고    scopus 로고
    • Calcium-dependent stabilization of type i plasminogen activator inhibitor within platelet alpha-granules
    • I.M. Lang, and R.R. Schleef Calcium-dependent stabilization of type I plasminogen activator inhibitor within platelet alpha-granules J Biol Chem 271 1996 2754 2761
    • (1996) J Biol Chem , vol.271 , pp. 2754-2761
    • Lang, I.M.1    Schleef, R.R.2
  • 12
    • 0021053614 scopus 로고
    • Evidence for a rapid inhibitor to tissue plasminogen activator in plasma
    • J. Chmielewska, M. Ranby, and B. Wiman Evidence for a rapid inhibitor to tissue plasminogen activator in plasma Thromb Res 31 1983 427 436
    • (1983) Thromb Res , vol.31 , pp. 427-436
    • Chmielewska, J.1    Ranby, M.2    Wiman, B.3
  • 13
    • 0025021029 scopus 로고
    • The mechanism of the reaction between human plasminogen-activator inhibitor 1 and tissue plasminogen activator
    • T.L. Lindahl, P.I. Ohlsson, and B. Wiman The mechanism of the reaction between human plasminogen-activator inhibitor 1 and tissue plasminogen activator Biochem J 265 1990 109 113
    • (1990) Biochem J , vol.265 , pp. 109-113
    • Lindahl, T.L.1    Ohlsson, P.I.2    Wiman, B.3
  • 15
    • 0028006095 scopus 로고
    • Platelets inhibit fibrinolysis in vitro by both plasminogen activator inhibitor-1-dependent and -independent mechanisms
    • W.P. Fay, D.T. Eitzman, A.D. Shapiro, E.L. Madison, and D. Ginsburg Platelets inhibit fibrinolysis in vitro by both plasminogen activator inhibitor-1-dependent and -independent mechanisms Blood 83 1994 351 356
    • (1994) Blood , vol.83 , pp. 351-356
    • Fay, W.P.1    Eitzman, D.T.2    Shapiro, A.D.3    Madison, E.L.4    Ginsburg, D.5
  • 16
    • 0030762720 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 (PAI-1) content in platelets from healthy individuals genotyped for the 4G/5G polymorphism in the PAI-1 gene
    • A. Nordenhem, and B. Wiman Plasminogen activator inhibitor-1 (PAI-1) content in platelets from healthy individuals genotyped for the 4G/5G polymorphism in the PAI-1 gene Scand J Clin Lab Invest 57 1997 453 461
    • (1997) Scand J Clin Lab Invest , vol.57 , pp. 453-461
    • Nordenhem, A.1    Wiman, B.2
  • 18
    • 0027933421 scopus 로고
    • Plasminogen activator inhibitor-1 released from activated platelets plays a key role in thrombolysis resistance. Studies with thrombi generated in the Chandler loop
    • H.A. Stringer, P. van Swieten, H.F. Heijnen, J.J. Sixma, and H. Pannekoek Plasminogen activator inhibitor-1 released from activated platelets plays a key role in thrombolysis resistance. Studies with thrombi generated in the Chandler loop Arterioscler Thromb Vasc Biol 14 1994 1452 1458
    • (1994) Arterioscler Thromb Vasc Biol , vol.14 , pp. 1452-1458
    • Stringer, H.A.1    Van Swieten, P.2    Heijnen, H.F.3    Sixma, J.J.4    Pannekoek, H.5
  • 19
    • 10244249152 scopus 로고    scopus 로고
    • Platelets synthesize large amounts of active plasminogen activator inhibitor 1
    • H. Brogren, L. Karlsson, M. Andersson, L. Wang, D. Erlinge, and S. Jern Platelets synthesize large amounts of active plasminogen activator inhibitor 1 Blood 104 2004 3943 3948
    • (2004) Blood , vol.104 , pp. 3943-3948
    • Brogren, H.1    Karlsson, L.2    Andersson, M.3    Wang, L.4    Erlinge, D.5    Jern, S.6
  • 20
    • 0022354051 scopus 로고
    • Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction
    • A. Hamsten, B. Wiman, U. de Faire, and M. Blomback Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction N Engl J Med 313 1985 1557 1563
    • (1985) N Engl J Med , vol.313 , pp. 1557-1563
    • Hamsten, A.1    Wiman, B.2    De Faire, U.3    Blomback, M.4
  • 21
    • 0042093744 scopus 로고    scopus 로고
    • Acute release of plasminogen activator inhibitor-1 in ST-segment elevation myocardial infarction predicts mortality
    • J.P. Collet, G. Montalescot, E. Vicaut, A. Ankri, F. Walylo, and C. Lesty Acute release of plasminogen activator inhibitor-1 in ST-segment elevation myocardial infarction predicts mortality Circulation 108 2003 391 394
    • (2003) Circulation , vol.108 , pp. 391-394
    • Collet, J.P.1    Montalescot, G.2    Vicaut, E.3    Ankri, A.4    Walylo, F.5    Lesty, C.6
  • 22
    • 2442615812 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-type 1: Its plasma determinants and relation with cardiovascular risk
    • T. Hoekstra, J.M. Geleijnse, E.G. Schouten, and C. Kluft Plasminogen activator inhibitor-type 1: its plasma determinants and relation with cardiovascular risk Thromb Haemost 91 2004 861 872
    • (2004) Thromb Haemost , vol.91 , pp. 861-872
    • Hoekstra, T.1    Geleijnse, J.M.2    Schouten, E.G.3    Kluft, C.4
  • 23
    • 0027441963 scopus 로고
    • Fibrinolytic activity, clotting factors, and long-term incidence of ischaemic heart disease in the Northwick Park Heart Study
    • T.W. Meade, V. Ruddock, Y. Stirling, R. Chakrabarti, and G.J. Miller Fibrinolytic activity, clotting factors, and long-term incidence of ischaemic heart disease in the Northwick Park Heart Study Lancet 342 1993 1076 1079
    • (1993) Lancet , vol.342 , pp. 1076-1079
    • Meade, T.W.1    Ruddock, V.2    Stirling, Y.3    Chakrabarti, R.4    Miller, G.J.5
  • 28
    • 0034695685 scopus 로고    scopus 로고
    • The hemostatic system as a regulator of angiogenesis
    • T. Browder, J. Folkman, and S. Pirie-Shepherd The hemostatic system as a regulator of angiogenesis J Biol Chem 275 2000 1521 1524
    • (2000) J Biol Chem , vol.275 , pp. 1521-1524
    • Browder, T.1    Folkman, J.2    Pirie-Shepherd, S.3
  • 29
    • 0021118858 scopus 로고
    • Role of plasma, platelets, and endothelial cells in tumor metastasis
    • G.J. Gasic Role of plasma, platelets, and endothelial cells in tumor metastasis Cancer Metastasis Rev 3 1984 99 114
    • (1984) Cancer Metastasis Rev , vol.3 , pp. 99-114
    • Gasic, G.J.1
  • 30
    • 0035475987 scopus 로고    scopus 로고
    • The role of the coagulation system in tumour angiogenesis
    • G.F. Nash, D.C. Walsh, and A.K. Kakkar The role of the coagulation system in tumour angiogenesis Lancet Oncol 2 2001 608 613
    • (2001) Lancet Oncol , vol.2 , pp. 608-613
    • Nash, G.F.1    Walsh, D.C.2    Kakkar, A.K.3
  • 31
    • 0002982369 scopus 로고    scopus 로고
    • Tumor Growth: A Putative Role for Platelets
    • H.M. Verheul, and H.M. Pinedo Tumor Growth: A Putative Role for Platelets Oncologist 3 1998 II
    • (1998) Oncologist , vol.3
    • Verheul, H.M.1    Pinedo, H.M.2
  • 32
    • 0021365844 scopus 로고
    • Potential role of platelets in the pathogenesis of tumor metastasis
    • P. Mehta Potential role of platelets in the pathogenesis of tumor metastasis Blood 63 1984 55 63
    • (1984) Blood , vol.63 , pp. 55-63
    • Mehta, P.1
  • 33
    • 38949178835 scopus 로고    scopus 로고
    • Angiogenesis is regulated by a novel mechanism: Pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released
    • J.E. Italiano Jr., J.L. Richardson, S. Patel-Hett, E. Battinelli, A. Zaslavsky, and S. Short Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released Blood 111 2008 1227 1233
    • (2008) Blood , vol.111 , pp. 1227-1233
    • Italiano, Jr.J.E.1    Richardson, J.L.2    Patel-Hett, S.3    Battinelli, E.4    Zaslavsky, A.5    Short, S.6
  • 34
    • 79953826916 scopus 로고    scopus 로고
    • Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli
    • M. Chatterjee, Z. Huang, W. Zhang, L. Jiang, K. Hultenby, and L. Zhu Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli Blood 117 2011 3907 3911
    • (2011) Blood , vol.117 , pp. 3907-3911
    • Chatterjee, M.1    Huang, Z.2    Zhang, W.3    Jiang, L.4    Hultenby, K.5    Zhu, L.6
  • 35
    • 73949157474 scopus 로고    scopus 로고
    • Platelet thrombin receptor antagonism and atherothrombosis
    • D.J. Angiolillo, D. Capodanno, and S. Goto Platelet thrombin receptor antagonism and atherothrombosis Eur Heart J 31 2009 17 28
    • (2009) Eur Heart J , vol.31 , pp. 17-28
    • Angiolillo, D.J.1    Capodanno, D.2    Goto, S.3
  • 36
    • 78149336649 scopus 로고    scopus 로고
    • Thrombin receptor antagonists may become an important antiplatelet therapy for coronary artery disease
    • F. Van de Werf Thrombin receptor antagonists may become an important antiplatelet therapy for coronary artery disease Eur Heart J 31 2010 2575 2576
    • (2010) Eur Heart J , vol.31 , pp. 2575-2576
    • Van De Werf, F.1
  • 37
    • 58149280291 scopus 로고    scopus 로고
    • PCR-Based amplification of platelet mRNA sequences obtained from small-scale platelet samples
    • J.M. Rox, J. Muller, and B. Potzsch PCR-Based amplification of platelet mRNA sequences obtained from small-scale platelet samples Methods Mol Biol 496 2009 285 292
    • (2009) Methods Mol Biol , vol.496 , pp. 285-292
    • Rox, J.M.1    Muller, J.2    Potzsch, B.3
  • 38
    • 0021677450 scopus 로고
    • Detection and partial characterization of an inhibitor of plasminogen activator in human platelets
    • L.A. Erickson, M.H. Ginsberg, and D.J. Loskutoff Detection and partial characterization of an inhibitor of plasminogen activator in human platelets J Clin Invest 74 1984 1465 1472
    • (1984) J Clin Invest , vol.74 , pp. 1465-1472
    • Erickson, L.A.1    Ginsberg, M.H.2    Loskutoff, D.J.3
  • 39
    • 0028937232 scopus 로고
    • Conformational studies on plasminogen activator inhibitor (PAI-1) in active, latent, substrate, and cleaved forms
    • E. Sancho, P.J. Declerck, N.C. Price, S.M. Kelly, and N.A. Booth Conformational studies on plasminogen activator inhibitor (PAI-1) in active, latent, substrate, and cleaved forms Biochemistry 34 1995 1064 1069
    • (1995) Biochemistry , vol.34 , pp. 1064-1069
    • Sancho, E.1    Declerck, P.J.2    Price, N.C.3    Kelly, S.M.4    Booth, N.A.5
  • 40
    • 46549096814 scopus 로고
    • Immunoradiometric assay to measure the binding of a specific inhibitor to tissue-type plasminogen activator
    • R.R. Schleef, M. Sinha, and D.J. Loskutoff Immunoradiometric assay to measure the binding of a specific inhibitor to tissue-type plasminogen activator J Lab Clin Med 106 1985 408 415
    • (1985) J Lab Clin Med , vol.106 , pp. 408-415
    • Schleef, R.R.1    Sinha, M.2    Loskutoff, D.J.3
  • 42
    • 57149110022 scopus 로고    scopus 로고
    • High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA
    • P. Mestdagh, T. Feys, N. Bernard, S. Guenther, C. Chen, and F. Speleman High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA Nucleic Acids Res 36 2008 e143
    • (2008) Nucleic Acids Res , vol.36 , pp. 143
    • Mestdagh, P.1    Feys, T.2    Bernard, N.3    Guenther, S.4    Chen, C.5    Speleman, F.6
  • 43
    • 0030954682 scopus 로고    scopus 로고
    • The suicide substrate reaction between plasminogen activator inhibitor 1 and thrombin is regulated by the cofactors vitronectin and heparin
    • M. van Meijer, A. Smilde, G. Tans, M.E. Nesheim, H. Pannekoek, and A.J. Horrevoets The suicide substrate reaction between plasminogen activator inhibitor 1 and thrombin is regulated by the cofactors vitronectin and heparin Blood 90 1997 1874 1882
    • (1997) Blood , vol.90 , pp. 1874-1882
    • Van Meijer, M.1    Smilde, A.2    Tans, G.3    Nesheim, M.E.4    Pannekoek, H.5    Horrevoets, A.J.6
  • 44
    • 53149129492 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 protects endothelial cells from FasL-mediated apoptosis
    • K. Bajou, H. Peng, W.E. Laug, C. Maillard, A. Noel, and J.M. Foidart Plasminogen activator inhibitor-1 protects endothelial cells from FasL-mediated apoptosis Cancer Cell 14 2008 324 334
    • (2008) Cancer Cell , vol.14 , pp. 324-334
    • Bajou, K.1    Peng, H.2    Laug, W.E.3    Maillard, C.4    Noel, A.5    Foidart, J.M.6
  • 45
    • 18244389007 scopus 로고    scopus 로고
    • The pro- or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent
    • L. Devy, S. Blacher, C. Grignet-Debrus, K. Bajou, V. Masson, and R.D. Gerard The pro- or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent FASEB J 16 2002 147 154
    • (2002) FASEB J , vol.16 , pp. 147-154
    • Devy, L.1    Blacher, S.2    Grignet-Debrus, C.3    Bajou, K.4    Masson, V.5    Gerard, R.D.6
  • 46
    • 0023840967 scopus 로고
    • Measurement of plasminogen activator inhibitor 1 in biologic fluids with a murine monoclonal antibody-based enzyme-linked immunosorbent assay
    • P.J. Declerck, M.C. Alessi, M. Verstreken, E.K. Kruithof, I. Juhan-Vague, and D. Collen Measurement of plasminogen activator inhibitor 1 in biologic fluids with a murine monoclonal antibody-based enzyme-linked immunosorbent assay Blood 71 1988 220 225
    • (1988) Blood , vol.71 , pp. 220-225
    • Declerck, P.J.1    Alessi, M.C.2    Verstreken, M.3    Kruithof, E.K.4    Juhan-Vague, I.5    Collen, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.