-
1
-
-
0037429722
-
ErbB-4: mechanism of action and biology
-
Carpenter G.ErbB-4: mechanism of action and biology.Exp Cell Res. 2003;284:66-77.
-
(2003)
Exp Cell Res
, vol.284
, pp. 66-77
-
-
Carpenter, G.1
-
2
-
-
30544449081
-
A quantitative protein interaction network for the ErbB receptors using protein microarrays
-
Jones RB,Gordus A,Krall JA,MacBeath G.A quantitative protein interaction network for the ErbB receptors using protein microarrays.Nature. 2006;439:168-74.
-
(2006)
Nature
, vol.439
, pp. 168-174
-
-
Jones, R.B.1
Gordus, A.2
Krall, J.A.3
MacBeath, G.4
-
3
-
-
33746905531
-
Phosphotyrosine interactome of the ErbB-receptor kinase family
-
Schulze WX,Deng L,Mann M.Phosphotyrosine interactome of the ErbB-receptor kinase family.Mol Syst Biol. 2005;1 2005:0008.
-
(2005)
Mol Syst Biol
, vol.1
-
-
Schulze, W.X.1
Deng, L.2
Mann, M.3
-
4
-
-
0028170817
-
Receptor protein-tyrosine kinases and their signal transduction pathways
-
van der Geer P,Hunter T,Lindberg RA.Receptor protein-tyrosine kinases and their signal transduction pathways.Annu Rev Cell Biol. 1994;10:251-337.
-
(1994)
Annu Rev Cell Biol
, vol.10
, pp. 251-337
-
-
van der Geer P1
Hunter, T.2
Lindberg, R.A.3
-
5
-
-
44149120446
-
HER4 intracellular domain (4ICD) activity in the developing mammary gland and breast cancer
-
Jones FE.HER4 intracellular domain (4ICD) activity in the developing mammary gland and breast cancer.J Mammary Gland Biol Neoplasia. 2008;13:247-58.
-
(2008)
J Mammary Gland Biol Neoplasia
, vol.13
, pp. 247-258
-
-
Jones, F.E.1
-
6
-
-
44149089008
-
Role of ErbB4 in breast cancer. J Mammary Gland Biol Neoplasia
-
Sundvall M,Iljin K,Kilpinen S, et al.Role of ErbB4 in breast cancer. J Mammary Gland Biol Neoplasia. 2008;13:259-68.
-
(2008)
, vol.13
, pp. 259-268
-
-
Sundvall, M.1
Iljin, K.2
Kilpinen, S.3
-
7
-
-
36649016921
-
Molecular differentiation of early and late stage laryngeal squamous cell carcinoma: an exploratory analysis
-
Saglam O,Shah V,Worsham MJ.Molecular differentiation of early and late stage laryngeal squamous cell carcinoma: an exploratory analysis.Diagn Mol Pathol. 2007;16:218-21.
-
(2007)
Diagn Mol Pathol
, vol.16
, pp. 218-221
-
-
Saglam, O.1
Shah, V.2
Worsham, M.J.3
-
8
-
-
0004345993
-
Comparative analysis of the EGF-receptor family in pancreatic cancer: expression of HER-4 correlates with a favourable tumor stage
-
Thybusch-Bernhardt A,Beckmann S,Juhl H.Comparative analysis of the EGF-receptor family in pancreatic cancer: expression of HER-4 correlates with a favourable tumor stage.Int J Surg Investig. 2001;2:393-400.
-
(2001)
Int J Surg Investig
, vol.2
, pp. 393-400
-
-
Thybusch-Bernhardt, A.1
Beckmann, S.2
Juhl, H.3
-
9
-
-
41049084427
-
The status and role of ErbB receptors in human cancer
-
Uberall I,Kolar Z,Trojanec R,Berkovcova J,Hajduch M.The status and role of ErbB receptors in human cancer.Exp Mol Pathol. 2008;84:79-89.
-
(2008)
Exp Mol Pathol
, vol.84
, pp. 79-89
-
-
Uberall, I.1
Kolar, Z.2
Trojanec, R.3
Berkovcova, J.4
Hajduch, M.5
-
10
-
-
73549115638
-
Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3K/Akt signaling pathways
-
Ghayad SE,Vendrell JA,Larbi SB, et al.Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3K/Akt signaling pathways.Int J Cancer. 2010;126:545-62.
-
(2010)
Int J Cancer
, vol.126
, pp. 545-562
-
-
Ghayad, S.E.1
Vendrell, J.A.2
Larbi, S.B.3
-
11
-
-
33745714207
-
The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells
-
Naresh A,Long W,Vidal GA, et al.The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells.Cancer Res. 2006;66:6412-20.
-
(2006)
Cancer Res
, vol.66
, pp. 6412-6420
-
-
Naresh, A.1
Long, W.2
Vidal, G.A.3
-
12
-
-
0035266135
-
Expression of erbB-4/HER-4 growth factor receptor isoforms in ovarian cancer
-
Gilmour LM,Macleod KG,McCaig A, et al.Expression of erbB-4/HER-4 growth factor receptor isoforms in ovarian cancer.Cancer Res. 2001;61:2169-76.
-
(2001)
Cancer Res
, vol.61
, pp. 2169-2176
-
-
Gilmour, L.M.1
Macleod, K.G.2
McCaig, A.3
-
13
-
-
27144469023
-
Correlation between human epidermal growth factor receptor family (EGFR, HER2, HER3, HER4), phosphorylated Akt (P-Akt), and clinical outcomes after radiation therapy in carcinoma of the cervix
-
Lee CM,Shrieve DC,Zempolich KA, et al.Correlation between human epidermal growth factor receptor family (EGFR, HER2, HER3, HER4), phosphorylated Akt (P-Akt), and clinical outcomes after radiation therapy in carcinoma of the cervix.Gynecol Oncol. 2005;99:415-21.
-
(2005)
Gynecol Oncol
, vol.99
, pp. 415-421
-
-
Lee, C.M.1
Shrieve, D.C.2
Zempolich, K.A.3
-
14
-
-
33750997293
-
Phosphorylation of ErbB4 on tyrosine 1056 is critical for ErbB4 coupling to inhibition of colony formation by human mammary cell lines
-
Pitfield SE,Bryant I,Penington DJ,Park G,Riese DJ.Phosphorylation of ErbB4 on tyrosine 1056 is critical for ErbB4 coupling to inhibition of colony formation by human mammary cell lines.Oncol Res. 2006;16:179-93.
-
(2006)
Oncol Res
, vol.16
, pp. 179-193
-
-
Pitfield, S.E.1
Bryant, I.2
Penington, D.J.3
Park, G.4
Riese, D.J.5
-
15
-
-
0037456676
-
A constitutively active ErbB4 mutant inhibits drug-resistant colony formation by the DU-145 and PC-3 human prostate tumor cell lines
-
Williams EE,Trout LJ,Gallo RM, et al.A constitutively active ErbB4 mutant inhibits drug-resistant colony formation by the DU-145 and PC-3 human prostate tumor cell lines.Cancer Lett. 2003;192:67-74.
-
(2003)
Cancer Lett
, vol.192
, pp. 67-74
-
-
Williams, E.E.1
Trout, L.J.2
Gallo, R.M.3
-
16
-
-
78651427805
-
Ligand stimulation of ErbB4 and A constitutively-active ErbB4 mutant result in different biological responses in human pancreatic tumor cell lines
-
Mill CP,Gettinger KL,Riese DJ.Ligand stimulation of ErbB4 and A constitutively-active ErbB4 mutant result in different biological responses in human pancreatic tumor cell lines.Exp Cell Res. 2011;317:392-404.
-
(2011)
Exp Cell Res
, vol.317
, pp. 392-404
-
-
Mill, C.P.1
Gettinger, K.L.2
Riese, D.J.3
-
17
-
-
33846296953
-
A constitutively active ERBB4/HER4 allele with enhanced transcriptional coactivation and cell-killing activities
-
Vidal GA,Clark DE,Marrero L,Jones FE.A constitutively active ERBB4/HER4 allele with enhanced transcriptional coactivation and cell-killing activities.Oncogene. 2007;26:462-6.
-
(2007)
Oncogene
, vol.26
, pp. 462-466
-
-
Vidal, G.A.1
Clark, D.E.2
Marrero, L.3
Jones, F.E.4
-
18
-
-
30044452100
-
The ErbB-4 s80 intracellular domain is a constitutively active tyrosine kinase
-
Linggi B,Cheng QC,Rao AR,Carpenter G.The ErbB-4 s80 intracellular domain is a constitutively active tyrosine kinase.Oncogene. 2006;25:160-3.
-
(2006)
Oncogene
, vol.25
, pp. 160-163
-
-
Linggi, B.1
Cheng, Q.C.2
Rao, A.R.3
Carpenter, G.4
-
19
-
-
0032170045
-
Expression of the ErbB-neuregulin signaling network during human cerebellar development: implications for the biology of medulloblastoma
-
Gilbertson RJ,Clifford SC,MacMeekin W, et al.Expression of the ErbB-neuregulin signaling network during human cerebellar development: implications for the biology of medulloblastoma.Cancer Res. 1998;58:3932-41.
-
(1998)
Cancer Res
, vol.58
, pp. 3932-3941
-
-
Gilbertson, R.J.1
Clifford, S.C.2
MacMeekin, W.3
-
20
-
-
52649160344
-
EGFR family: structure physiology signalling and therapeutic targets
-
Burgess AW.EGFR family: structure physiology signalling and therapeutic targets.Growth Factors. 2008;26:263-74.
-
(2008)
Growth Factors
, vol.26
, pp. 263-274
-
-
Burgess, A.W.1
-
21
-
-
7944221151
-
Expression and co-expression of the members of the epidermal growth factor receptor (EGFR) family in invasive breast carcinoma
-
Abd El-Rehim DM,Pinder SE,Paish CE, et al.Expression and co-expression of the members of the epidermal growth factor receptor (EGFR) family in invasive breast carcinoma.Br J Cancer. 2004;91:1532-42.
-
(2004)
Br J Cancer
, vol.91
, pp. 1532-1542
-
-
Abd El-Rehim, D.M.1
Pinder, S.E.2
Paish, C.E.3
-
22
-
-
0032718015
-
Ribozyme-mediated down-regulation of ErbB-4 in estrogen receptor-positive breast cancer cells inhibits proliferation both in vitro and in vivo
-
Tang CK,Concepcion XZ,Milan M, et al.Ribozyme-mediated down-regulation of ErbB-4 in estrogen receptor-positive breast cancer cells inhibits proliferation both in vitro and in vivo.Cancer Res. 1999;59:5315-22.
-
(1999)
Cancer Res
, vol.59
, pp. 5315-5322
-
-
Tang, C.K.1
Concepcion, X.Z.2
Milan, M.3
-
23
-
-
70349556805
-
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4
-
Prickett TD,Agrawal NS,Wei X, et al.Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.Nat Genet. 2009;41:1127-32.
-
(2009)
Nat Genet
, vol.41
, pp. 1127-1132
-
-
Prickett, T.D.1
Agrawal, N.S.2
Wei, X.3
-
24
-
-
0030944455
-
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
-
Graus-Porta D,Beerli RR,Daly JM,Hynes NE.ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling.EMBO J. 1997;16:1647-55.
-
(1997)
EMBO J
, vol.16
, pp. 1647-1655
-
-
Graus-Porta, D.1
Beerli, R.R.2
Daly, J.M.3
Hynes, N.E.4
-
25
-
-
0032499779
-
ErbB2 expression increases the spectrum and potency of ligand-mediated signal transduction through ErbB4
-
Wang LM,Kuo A,Alimandi M, et al.ErbB2 expression increases the spectrum and potency of ligand-mediated signal transduction through ErbB4.Proc Natl Acad Sci U S A. 1998;95:6809-14.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6809-6814
-
-
Wang, L.M.1
Kuo, A.2
Alimandi, M.3
-
26
-
-
77950628416
-
Mechanisms of resistance to HER family targeting antibodies
-
Kruser TJ,Wheeler DL.Mechanisms of resistance to HER family targeting antibodies.Exp Cell Res. 2010;316:1083-100.
-
(2010)
Exp Cell Res
, vol.316
, pp. 1083-1100
-
-
Kruser, T.J.1
Wheeler, D.L.2
-
27
-
-
70649098325
-
Evolving novel anti-HER2 strategies
-
Jones KL,Buzdar AU.Evolving novel anti-HER2 strategies.Lancet Oncol. 2009;10:1179-87.
-
(2009)
Lancet Oncol
, vol.10
, pp. 1179-1187
-
-
Jones, K.L.1
Buzdar, A.U.2
-
28
-
-
0029118223
-
The cellular response to neuregulins is governed by complex interactions of the erbB receptor family
-
Riese DJ,van Raaij TM,Plowman GD,Andrews GC,Stern DF.The cellular response to neuregulins is governed by complex interactions of the erbB receptor family.Mol Cell Biol. 1995;15:5770-6.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5770-5776
-
-
Riese, D.J.1
van Raaij, T.M.2
Plowman, G.D.3
Andrews, G.C.4
Stern, D.F.5
-
29
-
-
33748316606
-
Phosphorylation of ErbB4 on Tyr1056 is critical for inhibition of colony formation by prostate tumor cell lines
-
Gallo RM,Bryant I,Fry R,Williams EE,Riese DJ.Phosphorylation of ErbB4 on Tyr1056 is critical for inhibition of colony formation by prostate tumor cell lines.Biochem Biophys Res Commun. 2006;349:372-82.
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 372-382
-
-
Gallo, R.M.1
Bryant, I.2
Fry, R.3
Williams, E.E.4
Riese, D.J.5
-
30
-
-
4344612132
-
Epidermal growth factor receptor family (EGFR, ErbB2-4) in gliomas and meningiomas
-
Andersson U,Guo D,Malmer B, et al.Epidermal growth factor receptor family (EGFR, ErbB2-4) in gliomas and meningiomas.Acta Neuropathol. 2004;108:135-42.
-
(2004)
Acta Neuropathol
, vol.108
, pp. 135-142
-
-
Andersson, U.1
Guo, D.2
Malmer, B.3
-
31
-
-
0023663092
-
Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing
-
Honegger AM,Dull TJ,Felder S, et al.Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing.Cell. 1987;51:199-209.
-
(1987)
Cell
, vol.51
, pp. 199-209
-
-
Honegger, A.M.1
Dull, T.J.2
Felder, S.3
-
32
-
-
13944269873
-
Cleavable ErbB4 isoform in estrogen receptor-regulated growth of breast cancer cells
-
Junttila TT,Sundvall M,Lundin M, et al.Cleavable ErbB4 isoform in estrogen receptor-regulated growth of breast cancer cells.Cancer Res. 2005;65:1384-93.
-
(2005)
Cancer Res
, vol.65
, pp. 1384-1393
-
-
Junttila, T.T.1
Sundvall, M.2
Lundin, M.3
-
33
-
-
67449146917
-
The juxtamembrane region of the EGF receptor functions as an activation domain
-
Red Brewer M,Choi SH,Alvarado D, et al.The juxtamembrane region of the EGF receptor functions as an activation domain.Mol Cell. 2009;34:641-51.
-
(2009)
Mol Cell
, vol.34
, pp. 641-651
-
-
Red Brewer, M.1
Choi, S.H.2
Alvarado, D.3
-
34
-
-
34547450199
-
The HER4 cytoplasmic domain, but not its C terminus, inhibits mammary cell proliferation
-
Feng SM,Sartor CI,Hunter D, et al.The HER4 cytoplasmic domain, but not its C terminus, inhibits mammary cell proliferation.Mol Endocrinol. 2007;21:1861-76.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 1861-1876
-
-
Feng, S.M.1
Sartor, C.I.2
Hunter, D.3
-
35
-
-
33748288086
-
The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells
-
Muraoka-Cook RS,Sandahl M,Husted C, et al.The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells.Mol Biol Cell. 2006;17:4118-29.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 4118-4129
-
-
Muraoka-Cook, R.S.1
Sandahl, M.2
Husted, C.3
-
36
-
-
35148858828
-
Association of Wwox with ErbB4 in breast cancer
-
Aqeilan RI,Donati V,Gaudio E, et al.Association of Wwox with ErbB4 in breast cancer.Cancer Res. 2007;67:9330-6.
-
(2007)
Cancer Res
, vol.67
, pp. 9330-9336
-
-
Aqeilan, R.I.1
Donati, V.2
Gaudio, E.3
-
38
-
-
1642442499
-
Epidermal growth factor receptor inhibitors: a new prospective in the treatment of lung cancer
-
Tiseo M,Loprevite M,Ardizzoni A.Epidermal growth factor receptor inhibitors: a new prospective in the treatment of lung cancer.Curr Med Chem Anticancer Agents. 2004;4:139-48.
-
(2004)
Curr Med Chem Anticancer Agents
, vol.4
, pp. 139-148
-
-
Tiseo, M.1
Loprevite, M.2
Ardizzoni, A.3
-
39
-
-
0141645488
-
Mechanism of action of anti-HER2 monoclonal antibodies: scientific update on trastuzumab and 2C4
-
Albanell J,Codony J,Rovira A,Mellado B,Gascon P.Mechanism of action of anti-HER2 monoclonal antibodies: scientific update on trastuzumab and 2C4.Adv Exp Med Biol. 2003;532:253-68.
-
(2003)
Adv Exp Med Biol
, vol.532
, pp. 253-268
-
-
Albanell, J.1
Codony, J.2
Rovira, A.3
Mellado, B.4
Gascon, P.5
-
40
-
-
33746905493
-
Rationale for a phase II trial of pertuzumab, a HER-2 dimerization inhibitor, in patients with non-small cell lung cancer
-
Johnson BE,Janne PA.Rationale for a phase II trial of pertuzumab, a HER-2 dimerization inhibitor, in patients with non-small cell lung cancer.Clin Cancer Res. 2006;12:.
-
(2006)
Clin Cancer Res
, vol.12
-
-
Johnson, B.E.1
Janne, P.A.2
-
42
-
-
0027447680
-
Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family
-
Plowman GD,Culouscou JM,Whitney GS, et al.Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family.Proc Natl Acad Sci U S A. 1993;90:1746-50.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1746-1750
-
-
Plowman, G.D.1
Culouscou, J.M.2
Whitney, G.S.3
-
43
-
-
0025757389
-
Tumorigenic transformation of murine keratinocytes by the E5 genes of bovine papillomavirus type 1 and human papillomavirus type 16
-
Leptak C,Ramon Y,Cajal S,Kulke R, et al.Tumorigenic transformation of murine keratinocytes by the E5 genes of bovine papillomavirus type 1 and human papillomavirus type 16.J Virol. 1991;65:7078-83.
-
(1991)
J Virol
, vol.65
, pp. 7078-7083
-
-
Leptak, C.1
Ramon, Y.2
Cajal, S.3
Kulke, R.4
-
44
-
-
0028964483
-
An intact PDGF signaling pathway is required for efficient growth transformation of mouse C127 cells by the bovine papillomavirus E5 protein
-
Riese DJ,DiMaio D.An intact PDGF signaling pathway is required for efficient growth transformation of mouse C127 cells by the bovine papillomavirus E5 protein.Oncogene. 1995;10:1431-9.
-
(1995)
Oncogene
, vol.10
, pp. 1431-1439
-
-
Riese, D.J.1
DiMaio, D.2
-
45
-
-
35548980450
-
Inter-conversion of neuregulin2 full and partial agonists for ErbB4
-
Wilson KJ,Mill CP,Cameron EM, et al.Inter-conversion of neuregulin2 full and partial agonists for ErbB4.Biochem Biophys Res Commun. 2007;364:351-7.
-
(2007)
Biochem Biophys Res Commun
, vol.364
, pp. 351-357
-
-
Wilson, K.J.1
Mill, C.P.2
Cameron, E.M.3
-
46
-
-
0020582124
-
Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus
-
Mann R,Mulligan RC,Baltimore D.Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus.Cell. 1983;33:153-9.
-
(1983)
Cell
, vol.33
, pp. 153-159
-
-
Mann, R.1
Mulligan, R.C.2
Baltimore, D.3
-
47
-
-
0022767368
-
Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production
-
Miller AD,Buttimore C.Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production.Mol Cell Biol. 1986;6:2895-902.
-
(1986)
Mol Cell Biol
, vol.6
, pp. 2895-2902
-
-
Miller, A.D.1
Buttimore, C.2
-
48
-
-
0035989898
-
Constitutively active ErbB4 and ErbB2 mutants exhibit distinct biological activities
-
Penington DJ,Bryant I,Riese DJ.Constitutively active ErbB4 and ErbB2 mutants exhibit distinct biological activities.Cell Growth Differ. 2002;13:247-56.
-
(2002)
Cell Growth Differ
, vol.13
, pp. 247-256
-
-
Penington, D.J.1
Bryant, I.2
Riese, D.J.3
-
49
-
-
0032080266
-
Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2
-
Riese DJ,Komurasaki T,Plowman GD,Stern DF.Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2.J Biol Chem. 1998;273:11288-94.
-
(1998)
J Biol Chem
, vol.273
, pp. 11288-11294
-
-
Riese, D.J.1
Komurasaki, T.2
Plowman, G.D.3
Stern, D.F.4
-
50
-
-
79951996245
-
A high throughput, interactive imaging, bright-field wound healing assay
-
Zordan MD,Mill CP,Riese DJ,Leary JF.A high throughput, interactive imaging, bright-field wound healing assay.Cytometry A. 2011;:227-32.
-
(2011)
Cytometry A
, pp. 227-232
-
-
Zordan, M.D.1
Mill, C.P.2
Riese, D.J.3
Leary, J.F.4
-
51
-
-
1342280368
-
Five carboxyl-terminal residues of neuregulin2 are critical for stimulation of signaling by the ErbB4 receptor tyrosine kinase
-
Hobbs SS,Cameron EM,Hammer RP, et al.Five carboxyl-terminal residues of neuregulin2 are critical for stimulation of signaling by the ErbB4 receptor tyrosine kinase.Oncogene. 2004;23:883-93.
-
(2004)
Oncogene
, vol.23
, pp. 883-893
-
-
Hobbs, S.S.1
Cameron, E.M.2
Hammer, R.P.3
|