The inability of tapeworm Hymenolepis diminuta and fluke Dicrocoelium dendriticum to metabolize praziquantel

Veterinary Parasitology

Volumn 185, Issue 2-4, 2012, Pages 168-174

  Vokřál, Ivan ^a   Jirásko, Robert ^b   Jedličková, Veronika ^b   Bártíková, Hana ^a   Skálová, Lenka ^a   Lamka, Jiří ^a   Holčapek, Michal ^b   Szotáková, Barbora ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^b UNIVERSITY OF PARDUBICE   (Czech Republic)

Author keywords

Biotransformation; Dicrocoelium dendriticum; Hymenolepis diminuta; Praziquantel

Indexed keywords

PRAZIQUANTEL;

ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DICROCOELIUM; DICROCOELIUM DENDRITICUM; DRUG METABOLISM; DRUG URINE LEVEL; ENZYME METABOLISM; EX VIVO STUDY; FEMALE; HOST RANGE; HYMENOLEPIS DIMINUTA; INCUBATION TIME; LIQUID LIQUID EXTRACTION; LIVER HOMOGENATE; METABOLITE; MICROBIAL METABOLISM; MICROSOME; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; RAT; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; ANTHELMINTICS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DICROCOELIASIS; DICROCOELIUM; FEMALE; HEPATOCYTES; HYMENOLEPIASIS; HYMENOLEPIS DIMINUTA; PRAZIQUANTEL; RATS; RATS, WISTAR; TANDEM MASS SPECTROMETRY;

DICROCOELIUM DENDRITICUM; HYMENOLEPIS DIMINUTA; RATTUS; VERMES;

EID: 84858289982     PISSN: 03044017     EISSN: 18732550     Source Type: Journal    
DOI: 10.1016/j.vetpar.2011.09.026     Document Type: Article

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