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Volumn 23, Issue 3, 2012, Pages 298-304

Rational polytherapy with lacosamide in clinical practice: Results of a Spanish cohort analysis RELACOVA

Author keywords

Antiepileptic drug; Lacosamide; Observational study; Partial onset epilepsy; Polytherapy; Refractory epilepsy; Sodium channel blocker

Indexed keywords

CARBAMAZEPINE; ETIRACETAM; GABAPENTIN; HARKOSERIDE; LAMOTRIGINE; OXCARBAZEPINE; PHENYTOIN; PREGABALIN; TOPIRAMATE; VALPROIC ACID; ZONISAMIDE;

EID: 84858284935     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2011.11.026     Document Type: Article
Times cited : (80)

References (31)
  • 1
    • 0034598762 scopus 로고    scopus 로고
    • Early identification of refractory epilepsy
    • Kwan P., Brodie M.J. Early identification of refractory epilepsy. NEJM 2000, 342:314-319.
    • (2000) NEJM , vol.342 , pp. 314-319
    • Kwan, P.1    Brodie, M.J.2
  • 2
    • 34248335431 scopus 로고    scopus 로고
    • A new look at the second-generation antiepileptic drugs: a decade of experience
    • LaRoche S.M. A new look at the second-generation antiepileptic drugs: a decade of experience. Neurologist 2007, 13:133-139.
    • (2007) Neurologist , vol.13 , pp. 133-139
    • LaRoche, S.M.1
  • 3
    • 37349071555 scopus 로고    scopus 로고
    • The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels
    • Errington A.C., Stohr T., Heers C., Lees G. The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels. Mol Pharmacol 2008, 73:157-169.
    • (2008) Mol Pharmacol , vol.73 , pp. 157-169
    • Errington, A.C.1    Stohr, T.2    Heers, C.3    Lees, G.4
  • 4
    • 11144232600 scopus 로고    scopus 로고
    • Basic clinical pharmacological investigations of the new antiepileptic drug SPM-927 [abstract no. 2.174]
    • Horstmann R., Bonn R., Cawello W., Doty F., Rudd G.D. Basic clinical pharmacological investigations of the new antiepileptic drug SPM-927 [abstract no. 2.174]. Epilepsia 2002, 43:188.
    • (2002) Epilepsia , vol.43 , pp. 188
    • Horstmann, R.1    Bonn, R.2    Cawello, W.3    Doty, F.4    Rudd, G.D.5
  • 6
    • 84858284877 scopus 로고    scopus 로고
    • European Medicines Agency, in Spanish, European Medicines Agency, [cited 2011 August 2]; Available from:
    • European Medicines Agency Vimpat: Ficha Técnica O Resumen De Las Características Del Producto 2009, in Spanish, European Medicines Agency, [cited 2011 August 2]; Available from:. http://www.ema.europa.eu/docs/es_ES/document_library/EPAR_-_Product_Information/human/000863/WC500050338.pdf.
    • (2009) Vimpat: Ficha Técnica O Resumen De Las Características Del Producto
  • 7
    • 84858294730 scopus 로고    scopus 로고
    • UCB Pharma Limited, [cited 2011 July 25]; Available from:
    • UCB Pharma Limited Vimpat summary of product characteristics. electronic medicines compendium 2011, [cited 2011 July 25]; Available from:. http://www.medicines.org.uk/EMC/printfriendlydocument.aspx?documentid=21158&companyid=133.
    • (2011) Vimpat summary of product characteristics. electronic medicines compendium
  • 8
    • 34447344551 scopus 로고    scopus 로고
    • Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures
    • Ben-Menachem E., Biton V., Jatuzis D., Abou-Khalil B., Doty P., Rudd G.D. Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures. Epilepsia 2007, 48:1308-1317.
    • (2007) Epilepsia , vol.48 , pp. 1308-1317
    • Ben-Menachem, E.1    Biton, V.2    Jatuzis, D.3    Abou-Khalil, B.4    Doty, P.5    Rudd, G.D.6
  • 9
    • 77953033494 scopus 로고    scopus 로고
    • Lacosamide as adjunctive therapy for partial-onset seizures: a randomized controlled trial
    • Chung S., Sperling M.R., Biton V., et al. Lacosamide as adjunctive therapy for partial-onset seizures: a randomized controlled trial. Epilepsia 2010, 51:958-967.
    • (2010) Epilepsia , vol.51 , pp. 958-967
    • Chung, S.1    Sperling, M.R.2    Biton, V.3
  • 10
    • 61849088333 scopus 로고    scopus 로고
    • Adjunctive lacosamide for partial-onset seizures: efficacy and safety results from a randomized controlled trial
    • Halasz P., Kalviainen R., Mazurkiewicz-Beldzinska M., et al. Adjunctive lacosamide for partial-onset seizures: efficacy and safety results from a randomized controlled trial. Epilepsia 2009, 50:443-453.
    • (2009) Epilepsia , vol.50 , pp. 443-453
    • Halasz, P.1    Kalviainen, R.2    Mazurkiewicz-Beldzinska, M.3
  • 11
    • 11944254599 scopus 로고
    • Relating pharmacology to clinical practice: the pharmacologic basis of rational polypharmacy
    • Ferrendelli J.A. Relating pharmacology to clinical practice: the pharmacologic basis of rational polypharmacy. Neurology 1995, 45:S12-S16.
    • (1995) Neurology , vol.45
    • Ferrendelli, J.A.1
  • 12
    • 68949213747 scopus 로고    scopus 로고
    • Rational polytherapy
    • French J.A., Faught E. Rational polytherapy. Epilepsia 2009, 50(Suppl. 8):63-68.
    • (2009) Epilepsia , vol.50 , Issue.SUPPL. 8 , pp. 63-68
    • French, J.A.1    Faught, E.2
  • 13
    • 79955685813 scopus 로고    scopus 로고
    • Combining antiepileptic drugs-rational polytherapy?
    • Brodie M.J., Sills G.J. Combining antiepileptic drugs-rational polytherapy?. Seizure 2011, 20:369-375.
    • (2011) Seizure , vol.20 , pp. 369-375
    • Brodie, M.J.1    Sills, G.J.2
  • 14
    • 78649357007 scopus 로고    scopus 로고
    • A pooled analysis of lacosamide clinical trial data grouped by mechanism of action of concomitant antiepileptic drugs
    • Sake J.-K., Hebert D., Isojarvi J., et al. A pooled analysis of lacosamide clinical trial data grouped by mechanism of action of concomitant antiepileptic drugs. CNS Drugs 2010, 24:1055-1068.
    • (2010) CNS Drugs , vol.24 , pp. 1055-1068
    • Sake, J.-K.1    Hebert, D.2    Isojarvi, J.3
  • 15
    • 0019509687 scopus 로고
    • From the Commission on Classification and Terminology of the International League against Epilepsy
    • Proposal for revised clinical and electroencephalographic classification of epileptic seizures
    • Proposal for revised clinical and electroencephalographic classification of epileptic seizures From the Commission on Classification and Terminology of the International League against Epilepsy. Epilepsia 1981, 22:489-501.
    • (1981) Epilepsia , vol.22 , pp. 489-501
  • 16
    • 79954606109 scopus 로고    scopus 로고
    • Efficacy and tolerability of oral lacosamide as adjunctive therapy in pediatric patients with pharmacoresistant focal epilepsy
    • Gavatha M., Ioannou I., Papavasiliou A.S. Efficacy and tolerability of oral lacosamide as adjunctive therapy in pediatric patients with pharmacoresistant focal epilepsy. Epilepsy Behav 2011, 20:691-693.
    • (2011) Epilepsy Behav , vol.20 , pp. 691-693
    • Gavatha, M.1    Ioannou, I.2    Papavasiliou, A.S.3
  • 17
    • 79955833087 scopus 로고    scopus 로고
    • Experience with lacosamide in a series of children with drug-resistant focal epilepsy
    • Guilhoto L.M., Loddenkemper T., Gooty V.D., et al. Experience with lacosamide in a series of children with drug-resistant focal epilepsy. Pediatr Neurol 2011, 44:414-419.
    • (2011) Pediatr Neurol , vol.44 , pp. 414-419
    • Guilhoto, L.M.1    Loddenkemper, T.2    Gooty, V.D.3
  • 18
    • 70449533094 scopus 로고    scopus 로고
    • Six months of postmarketing experience with adjunctive lacosamide in patients with pharmacoresistant focal epilepsy at a tertiary epilepsy center in Germany
    • Wehner T., Bauer S., Hamer H.M., et al. Six months of postmarketing experience with adjunctive lacosamide in patients with pharmacoresistant focal epilepsy at a tertiary epilepsy center in Germany. Epilepsy Behav 2009, 16:423-425.
    • (2009) Epilepsy Behav , vol.16 , pp. 423-425
    • Wehner, T.1    Bauer, S.2    Hamer, H.M.3
  • 22
    • 51449122846 scopus 로고    scopus 로고
    • Lacosamide: an interim evaluation of long-term safety and efficacy as oral adjunctive therapy in subjects with partial-onset seizures [abstract no. 3.191]
    • Rosenfeld W., Fountain N.B., Kaubrys G., Heinzen L., McShea C. Lacosamide: an interim evaluation of long-term safety and efficacy as oral adjunctive therapy in subjects with partial-onset seizures [abstract no. 3.191]. Epilepsia 2007, 48:318-319.
    • (2007) Epilepsia , vol.48 , pp. 318-319
    • Rosenfeld, W.1    Fountain, N.B.2    Kaubrys, G.3    Heinzen, L.4    McShea, C.5
  • 23
    • 77954625557 scopus 로고    scopus 로고
    • Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies
    • Kwan P., Arzimanoglou A., Berg A.T., et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia 2010, 51:1069-1077.
    • (2010) Epilepsia , vol.51 , pp. 1069-1077
    • Kwan, P.1    Arzimanoglou, A.2    Berg, A.T.3
  • 24
    • 79960010513 scopus 로고    scopus 로고
    • Clinical comparability of the new antiepileptic drugs in refractory partial epilepsy: a systematic review and meta-analysis
    • Costa J., Fareleira F., Ascencao R., Borges M., Sampaio C., Vaz-Carneiro A. Clinical comparability of the new antiepileptic drugs in refractory partial epilepsy: a systematic review and meta-analysis. Epilepsia 2011, 52:1280-1291.
    • (2011) Epilepsia , vol.52 , pp. 1280-1291
    • Costa, J.1    Fareleira, F.2    Ascencao, R.3    Borges, M.4    Sampaio, C.5    Vaz-Carneiro, A.6
  • 25
    • 36148981106 scopus 로고    scopus 로고
    • Results of treatment changes in patients with apparently drug-resistant chronic epilepsy
    • Luciano A.L., Shorvon S.D. Results of treatment changes in patients with apparently drug-resistant chronic epilepsy. Ann Neurol 2007, 62:375-381.
    • (2007) Ann Neurol , vol.62 , pp. 375-381
    • Luciano, A.L.1    Shorvon, S.D.2
  • 26
    • 37849053121 scopus 로고    scopus 로고
    • Quantifying the response to antiepileptic drugs: effect of past treatment history
    • Schiller Y., Najjar Y. Quantifying the response to antiepileptic drugs: effect of past treatment history. Neurology 2008, 70:54-65.
    • (2008) Neurology , vol.70 , pp. 54-65
    • Schiller, Y.1    Najjar, Y.2
  • 27
    • 33746924499 scopus 로고    scopus 로고
    • Comparison of the efficacy and tolerability of new antiepileptic drugs: what can we learn from long-term studies?
    • Zaccara G., Messori A., Cincotta M., Burchini G. Comparison of the efficacy and tolerability of new antiepileptic drugs: what can we learn from long-term studies?. Acta Neurol Scand 2006, 114:157-168.
    • (2006) Acta Neurol Scand , vol.114 , pp. 157-168
    • Zaccara, G.1    Messori, A.2    Cincotta, M.3    Burchini, G.4
  • 28
    • 37149005294 scopus 로고    scopus 로고
    • Long-term effects of levetiracetam and topiramate in clinical practice: a head-to-head comparison
    • Bootsma H.P., Ricker L., Diepman L., et al. Long-term effects of levetiracetam and topiramate in clinical practice: a head-to-head comparison. Seizure 2008, 17:19-26.
    • (2008) Seizure , vol.17 , pp. 19-26
    • Bootsma, H.P.1    Ricker, L.2    Diepman, L.3
  • 29
    • 78649339546 scopus 로고    scopus 로고
    • Examining the clinical utility of lacosamide: pooled analyses of three phase II/III clinical trials
    • Chung S., Ben-Menachem E., Sperling M.R., et al. Examining the clinical utility of lacosamide: pooled analyses of three phase II/III clinical trials. CNS Drugs 2010, 24:1041-1054.
    • (2010) CNS Drugs , vol.24 , pp. 1041-1054
    • Chung, S.1    Ben-Menachem, E.2    Sperling, M.R.3
  • 30
    • 78651251889 scopus 로고    scopus 로고
    • Lacosamide neurotoxicity associated with concomitant use of sodium channel-blocking antiepileptic drugs: a pharmacodynamic interaction?
    • Novy J., Patsalos P.N., Sander J.W., Sisodiya S.M. Lacosamide neurotoxicity associated with concomitant use of sodium channel-blocking antiepileptic drugs: a pharmacodynamic interaction?. Epilepsy Behav 2011, 20:20-23.
    • (2011) Epilepsy Behav , vol.20 , pp. 20-23
    • Novy, J.1    Patsalos, P.N.2    Sander, J.W.3    Sisodiya, S.M.4
  • 31
    • 84858285851 scopus 로고    scopus 로고
    • Long-term safety and efficacy of lacosamide as adjunctive therapy in patients with uncontrolled POS: results from a phase III open-label extension trial
    • Husain A., Faught E., Chung S., Isojarvi J., McShea C., Doty P. Long-term safety and efficacy of lacosamide as adjunctive therapy in patients with uncontrolled POS: results from a phase III open-label extension trial. Epilepsia 2011, 52(Suppl. 6):155.
    • (2011) Epilepsia , vol.52 , Issue.SUPPL. 6 , pp. 155
    • Husain, A.1    Faught, E.2    Chung, S.3    Isojarvi, J.4    McShea, C.5    Doty, P.6


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