Repeat dose study of the novel proapoptotic chemotherapeutic agent alpha-tocopheryloxy acetic acid in mice

Anti-Cancer Drugs

Volumn 23, Issue 4, 2012, Pages 455-464

  Hahn, Tobias ^a   Akporiaye, Emmanuel T ^a  

^a EARLE A CHILES RESEARCH INSTITUTE   (United States)

Author keywords

alpha tocopheryloxy acetic acid; cancer; pharmacokinetics; preclinical safety toxicity study; vitamin E analog

Indexed keywords

ALPHA TOCOPHEROL DERIVATIVE; ALPHA TOCOPHERYLOXY ACETIC ACID; UNCLASSIFIED DRUG;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CELL COUNT; BLOOD CHEMISTRY; BLOOD SAMPLING; BREAST CANCER; CANCER CHEMOTHERAPY; CECUM; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EFFICACY; DRUG HALF LIFE; DRUG SAFETY; FEMALE; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; ILEUM; IMMUNOHISTOCHEMISTRY; JEJUNUM; KIDNEY; LIVER; LIVER TOXICITY; LOW DRUG DOSE; LUNG; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PHARMACOLOGICAL PARAMETERS; PRIORITY JOURNAL; REPEATED DRUG DOSE; SINGLE DRUG DOSE; SPLEEN; TREATMENT DURATION; TUMOR GROWTH; TUMOR XENOGRAFT;

ANEMIA; ANIMALS; ANTINEOPLASTIC AGENTS; DRUG EVALUATION, PRECLINICAL; DRUG-INDUCED LIVER INJURY; FEMALE; MALE; MICE; MICE, INBRED BALB C; TOCOPHEROLS;

EID: 84858279418     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e32834f6271     Document Type: Article

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