Enthalpy-entropy compensation and cooperativity as thermodynamic epiphenomena of structural flexibility in ligand-receptor interactions

Journal of Molecular Biology

Volumn 417, Issue 5, 2012, Pages 454-467

  Ferrante, Andrea ^a   Gorski, Jack ^a  

^a BLOOD RESEARCH INSTITUTE   (United States)

Author keywords

antigen presentation; cooperativity; ligand receptor interaction; MHC class II; thermodynamics

Indexed keywords

CYCLOPEPTIDE; GLYCYLPROLYLLYSYLTYROSYLVALYLLYSYLGLUTAMINYLASPARAGINYLTHREONYLLEUCYLLYSYLLEUCYLALANYLTHREONINE; HLA DR1 ANTIGEN; LIGAND; MUTANT PROTEIN; RECEPTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENERGY; ENTHALPY; ENTROPY; HAEMOPHILUS INFLUENZAE; HYDROGEN BOND; LIGAND BINDING; MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; RECEPTOR BINDING; SOLVATION; THERMODYNAMICS; WILD TYPE;

EID: 84858277308     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.01.057     Document Type: Article

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