Potential of novel EPO derivatives in limb ischemia

Cardiology Research and Practice

Volumn 1, Issue 1, 2012, Pages

  Joshi, Dhiraj ^a   Tsui, Janice ^a   Yu, Rebekah ^a   Shiwen, Xu ^a   Selvakumar, Sadasivam ^a   Abraham, David J ^a   Baker, Daryll M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARA 290; ASIALO ERYTHROPOIETIN; CARBAMYLATED ERYTHROPOIETIN; CD131 ANTIGEN; CELL SURFACE PROTEIN; CYTOKINE; ERYTHROPOIETIN DERIVATIVE; HELIX B SURFACE PEPTIDE; HEMOGLOBIN; HUMAN ERYTHROPOIETIN RECEPTOR; JANUS KINASE 2; UNCLASSIFIED DRUG;

BLOOD VISCOSITY; BRAIN PROTECTION; CARDIOVASCULAR RISK; CELL MATURATION; CONFORMATIONAL TRANSITION; DRUG HALF LIFE; DRUG MECHANISM; ERYTHROCYTE LIFESPAN; ERYTHROPOIESIS; HEART PROTECTION; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HUMAN; KIDNEY FAILURE; LIMB ISCHEMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN QUATERNARY STRUCTURE; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION; THROMBOEMBOLISM;

EID: 84858272207     PISSN: None     EISSN: 20900597     Source Type: Journal    
DOI: 10.1155/2012/213785     Document Type: Review

References (46)

1. Henry A. J., Hevelone N. D., Belkin M., Nguyen L. L., Socioeconomic and hospital-related predictors of amputation for critical limb ischemia Journal of Vascular Surgery 2011 53 2 330 339
2. Marchesi S., Pasqualini L., Lombardini R., Vaudo G., Lupattelli G., Pirro M., Schillaci G., Mannarino E., Prostaglandin E1 improves endothelial function in critical limb ischemia Journal of Cardiovascular Pharmacology 2003 41 2 249 253 (Pubitemid 36135250)
3. Dormandy J. A., Rutherford R. B., Management of peripheral arterial disease (PAD). TASC Working Group. TransAtlantic Inter-Society Consensus (TASC) Journal of Vascular Surgery 2000 31 1, part 2 S1 S296
4. Management of Peripheral Arterial Disease (PAD), TransAtlantic Inter-Society Consensus (TASC) European Journal of Vascular and Endovascular Surgery 2000 19, supplemt A S1 S250
5. Takeshita S., Gal D., Leclerc G., Pickering J. G., Riessen R., Weir L., Isner J. M., Increased gene expression after liposome-mediated arterial gene transfer associated with intimal smooth muscle cell proliferation. In vitro and in vivo findings in a rabbit model of vascular injury Journal of Clinical Investigation 1994 93 2 652 661
6. Isner J. M., Pieczek A., Schainfeld R., Blair R., Haley L., Asahara T., Rosenfield K., Razvi S., Walsh K., Symes J. F., Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb The Lancet 1996 348 9024 370 374 (Pubitemid 26261511)
7. Baumgartner I., Pieczek A., Manor O., Blair R., Kearney M., Walsh K., Isner J. M., Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia Circulation 1998 97 12 1114 1123 (Pubitemid 28152883)
8. Tateishi-Yuyama E., Matsubara H., Murohara T., Ikeda U., Shintani S., Masaki H., Amano K., Kishimoto Y., Yoshimoto K., Akashi H., Shimada K., Iwasaka T., Imaizumi T., Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial The Lancet 2002 360 9331 427 435
9. Webster K. A., Therapeutic angiogenesis: a complex problem requiring a sophisticated approach Cardiovascular Toxicology 2003 3 3 283 297 (Pubitemid 37296080)
10. Erbayraktar S., Grasso G., Sfacteria A., Xie Q. W., Coleman T., Kreilgaard M., Torup L., Sager T., Erbayraktar Z., Gokmen N., Yilmaz O., Ghezzi P., Villa P., Fratelli M., Casagrande S., Leist M., Helboe L., Gerwein J., Christensen So. S.., Geist M. A., Pedersen L.., Cerami-Hand C., Wuerth J. P., Cerami A., Brines M., Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo Proceedings of the National Academy of Sciences of the United States of America 2003 100 11 6741 6746 (Pubitemid 36666650)
11. Leis M., Gliezzi P., Grasso G., Bianchi R., Vilia P., Fratelli M., Savino C., Bianchi M., Nielsen J., Gerwien J., Kallunki P., Kirstine Larsen A., Helboe L., Christensen S., Pedersen L. O., Nielsen M., Torup L., Sager T., Sfacteria A., Erbayraktar S., Erbayraktar Z., Gokmen N., Yilmaz O., Cerami-Hand C., Xie Q.-W., Coleman T., Cerami A., Brines M., Derivatives of erythropoitein that are tissue protective but not erythropoietic Science 2004 305 5681 239 242 (Pubitemid 38886736)
12. Fiordaliso F., Chimenti S., Staszewsky L., Bai A., Carlo E., Cuccovillo I., Doni M., Mengozzi M., Tonelli R., Ghezzi P., Coleman T., Brines M., Cerami A., Latini R., A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury Proceedings of the National Academy of Sciences of the United States of America 2005 102 6 2046 2051 (Pubitemid 40262009)
13. Fantacci M., Bianciardi P., Caretti A., Coleman T. R., Cerami A., Brines M., Samaja M., Carbamylated erythropoietin ameliorates the metabolic stress induced in vivo by severe chronic hypoxia Proceedings of the National Academy of Sciences of the United States of America 2006 103 46 17531 17536 (Pubitemid 44789003)
14. Erbayraktar S., de Lanerolle N., de Lotbinire A., Knisely J. P. S., Erbayraktar Z., Yilmaz O., Cerami A., Coleman T. R., Brines M., Carbamylated erythropoietin reduces radiosurgically-induced brain injury Molecular Medicine 2006 12 46 74 80 (Pubitemid 44454094)
15. Erbayraktar Z., Erbayraktar S., Yilmaz O., Cerami A., Coleman T., Brines M., Nonerythropoietic tissue protective compounds are highly effective facilitators of wound healing Molecular Medicine 2009 15 7-8 235 241
16. Ahmet I., Tae H. J., Juhaszova M., Riordon D. R., Boheler K. R., Sollott S. J., Brines M., Cerami A., Lakatta E. G., Talan M. I., A small nonerythropoietic helix B surface peptide based upon erythropoietin structure is cardioprotective against ischemic myocardial damage Molecular Medicine 2011 17 3-4 194 200
17. Joshi D., Tsui J., Shiwen X., Helix-B peptide of erythropoietin could be used as pharmacotherapy in critical limb ischaemia British Journal of Surgery 2011 98 2
18. Joshi D., Tsui J., Patel H., Role of erythropoietin receptors and ligands in attenuating inflammation and apoptosis in critical limb ischemia Journal of Vascular Surgery 2011 53 6, supplement 80S
19. Mitchell R. G., Duscha B. D., Robbins J. L., Redfern S. I., Chung J., Bensimhon D. R., Kraus W. E., Hiatt W. R., Regensteiner J. G., Annex B. H., Increased levels of apoptosis in gastrocnemius skeletal muscle in patients with peripheral arterial disease Vascular Medicine 2007 12 4 285 290
20. Ehrenreich H., Weissenborn K., Prange H., Schneider D., Weimar C., Wartenberg K., Schellinger P. D., Bohn M., Becker H., Wegrzyn M., Jhnig P., Herrmann M., Knauth M., Bhr M., Heide W., Wagner A., Schwab S., Reichmann H., Schwendemann G., Dengler R., Kastrup A., Bartels C., Recombinant human erythropoietin in the treatment of acute ischemic stroke Stroke 2009 40 12 e647 e656
21. Riksen N. P., Hausenloy D. J., Yellon D. M., Erythropoietin: ready for prime-time cardioprotection Trends in Pharmacological Sciences 2008 29 5 258 267
22. Bennett C. L., Silver S. M., Djulbegovic B., Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia JAMA 2008 299 8 914 924 (Pubitemid 351397066)
23. Brines M., Grasso G., Fiordaliso F., Sfacteria A., Ghezzi P., Fratelli M., Latini R., Xie Q. W., Smart J., Su-Rick C. J., Pobre E., Diaz D., Gomez D., Hand C., Coleman T., Cerami A., Erythropoietin mediates tissue protection through an erythropoietin and common -subunit heteroreceptor Proceedings of the National Academy of Sciences of the United States of America 2004 101 41 14907 14912 (Pubitemid 39410773)
24. Davis J. M., Arakawa T., Strickland T. W., Yphantis D. A., Characterization of recombinant human erythropoietin produced in Chinese hamster ovary cells Biochemistry 1987 26 9 2633 2638 (Pubitemid 17081496)
25. Elliott S., Lorenzini T., Chang D., Barzilay J., Delorme E., Mapping of the active site of recombinant human erythropoietin Blood 1997 89 2 493 502 (Pubitemid 27051684)
26. Budarf M., Huebner K., Emanuel B., Croce C. M., Copeland N. G., Jenkins N. A., D'Andrea A. D., Assignment of the erythropoietin receptor (EPOR) gene to mouse chromosome 9 and human chromosome 19 Genomics 1990 8 3 575 578
27. Bazan J. F., A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor -chain Biochemical and Biophysical Research Communications 1989 164 2 788 795 (Pubitemid 19280337)
28. Wojchowski D. M., He T. C., Signal transduction in the erythropoietin receptor system Stem Cells 1993 11 5 381 392 (Pubitemid 24007586)
29. Brines M., Cerami A., Emerging biological roles for erythropoietin in the nervous system Nature Reviews Neuroscience 2005 6 6 484 494 (Pubitemid 40769173)
30. Winearls C. G., Treatment of the anaemia of chornic renal failure with recombinant human erythropoietin Drugs 1989 38 3 342 345 (Pubitemid 19234435)
31. Ehrenreich H., Hasselblatt M., Dembowski C., Cepek L., Lewczuk P., Stiefel M., Rustenbeck H. H., Breiter N., Jacob S., Knerlich F., Bohn M., Poser W., Rther E., Kochen M., Gefeller O., Gleiter C., Wessel T. C., De Ryck M., Itri L., Prange H., Cerami A., Brines M., Sirén A. L., Erythropoietin therapy for acute stroke is both safe and beneficial Molecular Medicine 2002 8 8 495 505 (Pubitemid 36337492)
32. Yamaji R., Okada T., Moriya M., Naito M., Tsuruo T., Miyatake K., Nakano Y., Brain capillary endothelial cells express two forms of erythropoietin receptor mRNA European Journal of Biochemistry 1996 239 2 494 500 (Pubitemid 26246558)
33. Mingoli A., Sapienza P., Puggioni A., Modini C., Cavallaro A., A possible side-effect of human erythropoietin therapy: thrombosis of peripheral arterial reconstruction European Journal of Vascular and Endovascular Surgery 1999 18 3 273 274 (Pubitemid 29431355)
34. Zaoui P., Bayle F., Maurizi J., Foret M., DalSoglio S., Vialtel P., Early thrombosis in kidney grafted into patient treated with erythropoietin The Lancet 1988 2 8617 956
35. Dicato M., Plawny L., Erythropoietin in cancer patients: pros and cons Current Opinion in Oncology 2010 22 4 307 311
36. Hardee M. E., Kirkpatrick J. P., Shan S., Snyder S. A., Vujaskovic Z., Rabbani Z. N., Dewhirst M. W., Blackwell K. L., Human recombinant erythropoietin (rEpo) has no effect on tumour growth or angiogenesis British Journal of Cancer 2005 93 12 1350 1355 (Pubitemid 41752861)
37. Schiffl H., Lang S. M., Hypertension induced by recombinant human erythropoietin (rHU-EPO) can be prevented by indomethacin: pathogenetic role of cytosolic calcium European Journal of Medical Research 1997 2 3 97 100
38. Kuriyama S., Tokudome G., Tomonari H., Matsumoto H., Utsunomiya Y., Horiguchi M., Uchida H., Hashimoto T., Sakai O., Effect of human recombinant erythropoietin (Epo) on cellular Ca 2+, Na +, and K + regulation of vascular smooth muscle cells grown in vitroa new insight into the pathogenesis of Epo induced hypertension Japanese Journal of Nephrology 1993 35 6 671 678 (Pubitemid 23346011)
39. Ni Z., Wang X. Q., Vaziri N. D., Nitric oxide metabolism in erythropoietin-induced hypertension: effect of calcium channel blockade Hypertension 1998 32 4 724 729 (Pubitemid 28480551)
40. Brines M., Patel N. S. A., Villa P., Brines C., Mennini T., De Paola M., Erbayraktar Z., Erbayraktar S., Sepodes B., Thiemermann C., Ghezzi P., Yamin M., Hand C. C., Xie Q. W., Coleman T., Cerami A., Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin Proceedings of the National Academy of Sciences of the United States of America 2008 105 31 10925 10930
41. Brines M., Cerami A., Erythropoietin-mediated tissue protection: reducing collateral damage from the primary injury response Journal of Internal Medicine 2008 264 5 405 432
42. Rafiee P., Shi Y., Su J., Pritchard K. A., Tweddell J. S., Baker J. E., Erythropoietin protects the infant heart against ischemia-reperfusion injury by triggering multiple signaling pathways Basic Research in Cardiology 2005 100 3 187 197 (Pubitemid 41348809)
43. Digicaylioglu M., Garden G., Timberlake S., Fletcher L., Lipton S. A., Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I Proceedings of the National Academy of Sciences of the United States of America 2004 101 26 9855 9860 (Pubitemid 38869326)
44. Wen T. C., Sadamoto Y., Tanaka J., Zhu P. X., Nakata K., Yong-Jie M., Hata R., Sakanaka M., Erythropoietin protects neurons against chemical hypoxia and cerebral ischemic injury by up-regulating Bcl-x Journal of Neuroscience Research 2002 67 6 795 803 (Pubitemid 34226292)
45. Parsa C. J., Matsumoto A., Kim J., Riel R. U., Pascal L. S., Walton G. B., Thompson R. B., Petrofski J. A., Annex B. H., Stamler J. S., Koch W. J., A novel protective effect of erythropoietin in the infarcted heart Journal of Clinical Investigation 2003 112 7 999 1007 (Pubitemid 38056315)
46. Baker J. E., Kozik D., Hsu A. K., Fu X., Tweddell J. S., Gross G. J., Darbepoetin alfa protects the rat heart against infarction: dose-response, phase of action, and mechanisms Journal of Cardiovascular Pharmacology 2007 49 6 337 345 (Pubitemid 47000307)