IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites

Disease Markers

Volumn 32, Issue 2, 2012, Pages 133-141

  Hoyo, Cathrine ^a   Murphy, Susan K ^b   Schildkraut, Joellen M ^a   Vidal, Adriana C ^a   Skaar, David ^b   Millikan, Robert C ^c   Galanko, Joseph ^d   Sandler, Robert S ^d   Jirtle, Randy ^b   Keku, Temitope ^d  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c IL   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

colon cancer; IGF2 concentration; IGF2R polymorphism

Indexed keywords

SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR;

ADULT; AFRICAN AMERICAN; AGED; ALLELE; ARTICLE; CANCER RISK; CAUCASIAN; COLON CANCER; CONTROLLED STUDY; FEMALE; GENETIC VARIABILITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; SEX DIFFERENCE;

EID: 84858217366     PISSN: 02780240     EISSN: 18758630     Source Type: Journal    
DOI: 10.3233/DMA-2011-0865     Document Type: Article

References (56)

1. Cancer Facts and Figures, American Cancer Society, Atlanta, 2007.
2. A. Jemal, R. Siegel, E. Ward, T. Murray, J. Xu, C. Smigal et al., Cancer statistics, CA Cancer J Clin 56 (2006), 106-130.
3. K.R. Yabroff, K.S. Washington, A. Leader, E. Neilson and J. Mandelblatt, Is the promise of cancer-screening programs being compromised? Quality of follow-up care after abnormal screening results, Med Care Res Rev 60 (2003), 294-331. (Pubitemid 36993502)
4. R. Kaaks, The epidemiology of diet and colorectal cancer: review and perspectives for future research using biological markers, Annali dell'Istituto Superiore di Sanita 32 (1996), 111-121. (Pubitemid 126532096)
5. M.L. Slattery, M. Murtaugh, B. Caan, K.N. Ma, S. Neuhausen and W. Samowitz, Energy balance, insulin-related genes and risk of colon and rectal cancer, Int J Cancer 115 (2005), 148-154. (Pubitemid 40559681)
6. E. Giovannucci, M.N. Pollak, E.A. Platz, W.C. Willett, M.J. Stampfer, N. Majeed et al., A prospective study of plasma insulin-like growth factor-1 and binding protein-3 and risk of colorectal neoplasia in women, Cancer Epidemiol Biomarkers Prev 9 (2000), 345-349. (Pubitemid 30265776)
7. J. Ma, M.N. Pollak, E. Giovannucci, J.M. Chan, Y. Tao, C.H. Hennekens et al., Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3, J Natl Cancer Inst 91 (1999), 620-625. (Pubitemid 29194048)
8. A.M. Nomura, G.N. Stemmermann, J. Lee and N.M. Pollak, Serum insulin-like growth factor I and subsequent risk of col-orectal cancer among Japanese-American men, Am J Epidemiol 158 (2003), 424-431. (Pubitemid 37022840)
9. R. Palmqvist, G. Hallmans, S. Rinaldi, C. Biessy, R. Stenling, E. Riboli et al., Plasma insulin-like growth factor 1, insulinlike growth factor binding protein 3, and risk of colorectal cancer: a prospective study in northern Sweden, Gut 50 (2002), 642-646. (Pubitemid 34407490)
10. N.M. Probst-Hensch, J.M. Yuan, F.Z. Stanczyk, Y.T. Gao, R.K. Ross and M.C. Yu, IGF-1, IGF-2 and IGFBP-3 in pre-diagnostic serum: association with colorectal cancer in a cohort of Chinese men in Shanghai, Br J Cancer 85 (2001), 1695-1699. (Pubitemid 34081515)
11. M. Pollak, Insulin and insulin-like growth factor signalling in neoplasia, Nat Rev Cancer 8 (2008), 915-928.
12. G.R. Devi, A.T. De Souza, J.C. Byrd, R.L. Jirtle and R.G. Mac-Donald, Altered ligand binding by insulin-like growth factor II/mannose 6-phosphate receptors bearing missense mutations in human cancers, Cancer Res 59 (1999), 4314-4319. (Pubitemid 29418749)
13. J.K. Killian, Y. Oka, H.S. Jang, X. Fu, R.A. Waterland, T. Sohda et al., Mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) variants in American and Japanese populations, Hum Mutat 18 (2001), 25-31. (Pubitemid 32588475)
14. C. Hawkes and S. Kar, The insulin-like growth factor-II/mannose-6- phosphate receptor: structure, distribution and function in the central nervous system, Brain Res Rev 44 (2004), 117-140. (Pubitemid 38293429)
15. D. Rezgui, C. Williams, S.A. Savage, S.N. Prince, O.J. Zac-cheo, E.Y. Jones et al., Structure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growth, J Mol Endocrinol 42 (2009), 341-356.
16. J. Brown, C. Delaine, O.J. Zaccheo, C. Siebold, R.J. Gilbert, G. van Boxel, A. Denley et al., Structure and functional analy-sis of the IGF-II/IGF2R interaction, EMBO J 27 (2008), 265-276.
17. C. Williams, D. Rezgui, S.N. Prince, O.J. Zaccheo, E.J. Foul-stone, B.E. Forbes et al., Structural insights into the interaction of insulin-like growth factor 2 with IGF2R domain 11, Structure 15 (2007), 1065-1078. (Pubitemid 47371203)
18. P. Ghosh, N.M. Dahms and S. Kornfeld, Mannose 6-phosphate receptors: new twists in the tale, Nat Rev Mol Cell Biol 4 (2003), 202-212. (Pubitemid 36288042)
19. Z.Q. Wang, M.R. Fung, D.P. Barlow and E.F. Wagner, Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene, Nature 372 (1994), 464-467. (Pubitemid 24365453)
20. T. Ludwig, J. Eggenschwiler, P. Fisher, A.J. D'Ercole, M.L. Davenport and A. Efstratiadis, Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds, Dev Biol 177 (1996), 517-535. (Pubitemid 26275902)
21. A.J. Oates, L.M. Schumaker, S.B. Jenkins, A.A. Pearce, S.A. DaCosta, B. Arun et al., The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene, Breast Cancer Res Treat 47 (1998), 269-281. (Pubitemid 28059822)
22. F.M. Kong, M.S. Anscher, M.K. Washington, J.K. Killian and R.L. Jirtle, M6P/IGF2R is mutated in squamous cell carcinoma of the lung, Oncogene 19 (2000), 1572-1578. (Pubitemid 30175679)
23. S.A. Savage, K. Woodson, E. Walk, W. Modi, J. Liao, C. Douglass et al., Analysis of genes critical for growth regulation identifies Insulin-like Growth Factor 2 Receptor variations with possible functional significance as risk factors for osteosarcoma, Cancer Epidemiol Biomarkers Prev 16 (2007), 1667-1674. (Pubitemid 47294836)
24. Affymetrix IUS. Products and Services, in: Santa Clara: Affymetrix, Inc., 2009.
25. I. Illumina, Products and Services, in: Illumina I, San Diego: Illumina, Inc., ed., 2009.
26. J. Satia-Abouta, J.A. Galanko, J.D. Potter, A. Ammerman, C.F. Martin and R.S. Sandler, Associations of total energy and macronutrients with colon cancer risk in African Americans and Whites: results from the North Carolina colon cancer study, Am J Epidemiol 158 (2003), 951-962. (Pubitemid 37413394)
27. C.R. Weinberg and D.P. Sandler, Randomized recruitment in case-control studies, Am J Epidemiol 134 (1991), 421-432.
28. C.R. Weinberg and S. Wacholder, The design and analysis of case-control studies with biased sampling, Biometrics 46 (1990), 963-975.
29. G. Block, Dietary guidelines and the results of food consumption surveys, Am J Clin Nutr 53 (1991), 356S-357S.
30. G. Block, A.M. Hartman, C.M. Dresser, M.D. Carroll, J. Gannon and L. Gardner, A data-based approach to diet questionnaire design and testing, Am J Epidemiol 124 (1986), 453-469. (Pubitemid 16047362)
31. J. Satia-Abouta, J.A. Galanko, C.F. Martin, A. Ammerman and R.S. Sandler, Food groups and colon cancer risk in African-Americans and Caucasians, Int J Cancer 109 (2004), 728-736. (Pubitemid 38405621)
32. T. Keku, R. Millikan, K. Worley, S. Winkel, A. Eaton, L. Bis-cocho et al., 5,10-Methylenetetrahydrofolate reductase codon 677 and 1298 polymorphisms and colon cancer in African Americans and Whites, Cancer Epidemiol Biomarkers Prev 11 (2002), 1611-1621. (Pubitemid 36020015)
33. T.O. Keku, P.K.Lund, J. Galanko, J.G. Simmons, J.T. Woosley and R.S. Sandler, Insulin resistance, apoptosis, and colorectal adenoma risk, Cancer Epidemiol Biomarkers Prev 14 (2005), 2076-2081. (Pubitemid 41603248)
34. H. Cui, M. Cruz-Correa, F.M. Giardiello, D.F. Hutcheon, D.R. Kafonek, S. Brandenburg et al., Loss of IGF2 imprinting: a potential marker of colorectal cancer risk, Science 299 (2003), 1753-1755. (Pubitemid 36337205)
35. M. Cruz-Correa, H. Cui, F.M. Giardiello, N.R. Powe, L. Hylind, A. Robinson et al., Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition, Gastroenterology 126 (2004), 964-970. (Pubitemid 38451167)
36. N.M. Dahms, D.A. Wick and M.A. Brzycki-Wessell, The bovine mannose 6-phosphate/insulin-like growth factor II receptor. Localization of the insulin-like growth factor II binding site to domains 5-11, J Biol Chem 269 (1994), 3802-3809.
37. F. Garmroudi and R.G. MacDonald, Localization of the insulin-like growth factor II (IGF-II) binding/cross-linking site of the IGF-II/mannose 6-phosphate receptor to extracellular repeats 10-11, J Biol Chem 269 (1994), 26944-26952.
38. A.J. Yoon, A.I. Zavras, M.-K. Chen, C.-W. Lin and S.-F. Yang, Association between Gly1619ARG polymorphism of IGF2R domain 11 (rs629849) and advanced stage of oral cancer, Med Oncol (2011) DOI 10.1007/s12032-011-9863-6.
39. X. Dong, Y. Li, H. Tang, P. Chang, K.R. Hess, J.L. Abbruzesse and D. Li, Insulin-like growth factor axis gene polymosphisms modify risk of pancreatic cancer, Cancer Epidemiol (2011), in press.
40. R. Zhao, M. Berho, J. Nogueras, D. Sands, E. Weiss, S. Wexner et al., Positive correlation of insulin-like growth factor-II with proliferating cell index in patients with colorectal neoplasia, Cancer Epidemiol Biomarkers Prev 14 (2005), 1819-1822. (Pubitemid 40995100)
41. A.G. Renehan, J. Jones, C.S. Potten, S.M. Shalet and S.T. O'Dwyer, Elevated serum insulin-like growth factor (IGF)-II and IGF binding protein-2 in patients with colorectal cancer, Br J Cancer 83 (2000), 1344-1350.
42. M. Cruz-Correa, R. Zhao, M. Oviedo, R.D. Bernabe, M. La-court, A. Cardona et al., Temporal stability and age-related prevalence of loss of imprinting of the insulin-like growth factor-2 gene, Epigenetics 4 (2009), 114-118.
43. H. Cui, Loss of imprinting of IGF2 as an epigenetic marker for the risk of human cancer, Dis Markers 23 (2007), 105-112. (Pubitemid 46333644)
44. J.A. Toresky and L.J. Helman, Involvement of IGF-ii in human cancer J Endocrinol 149 (1996), 367-372. (Pubitemid 26196067)
45. A.B. Hassan and J.A. Howell, Insulin-like growth factor II SUPPLy modifies growth of intestinal adenoma in Apc(Min/+) mice, Cancer Epidemiol Biomarkers Prev 9 (2000), 345-349.
46. D.O. Desmet, D. Hamroun, M. Lalande, G. Collod-Beroud, M. Claustres and C. Beroud, Human splicing finder: an online bioinformatics tool to predict splicing signals, Nucleic acids res 37 (2009), 1-14.
47. D.A. Skaar, Biological consequences of the divergent evolution of IGF2R imprinting, Keystone meeting on environmental epigenomics and disease susceptibility, (2011), Asheville, NC.
48. J. Wang, A. Caballero and W. Hill, The effect of linkage disequilibrium and deviation from Hardy-Weinberg proportions on the changes in genetic variance with bottlenecking, Heredity 81 (1998), 174-186. (Pubitemid 28403812)
49. A.T. De Souza, G.R. Hankins, M.K. Washington, T.C. Or-ton and R.L. Jirtle, M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity, Nature Genetics 11 (1995), 447-449.
50. G.R. Hankins, A.T. De Souza, R.C. Bentley, M.R. Patel, J.R. Marks, J.D. Iglehart et al., M6P/IGF2 receptor: a candidate breast tumor suppressor gene, Oncogene 12 (1996), 2003-2009. (Pubitemid 26154672)
51. J.K. Killian, J.C. Byrd, J.V. Jirtle, B.L. Munday, M.K. Stoskopf, R.G. MacDonald et al., M6P/IGF2R imprinting evolution in mammals, Mol Cell 5 (2000), 707-716.
52. K. Kaku, H. Osada, K. Seki and S. Sekiya, Insulin-like growth factor 2 (IGF2) and IGF2 receptor gene variants are associated with fetal growth, Acta Paediatr 96 (2007), 363-367. (Pubitemid 46439493)
53. C. Hoyo, J.M. Schildkraut, S.K. Murphy, W.H. Chow, T.L. Vaughan, H. Risch et al., IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas, Int J Cancer 125 (2009), 2673-2678.
54. C.J. Petry, K.K. Ong, B.J. Barratt, D. Wingate, H.J. Cordell, S.M. Ring et al., Common polymorphism in H19 associated with birth weight and cord blood IGF-II levels in humans, BMC Genet 6 (2005), 22.
55. A. Engeland, S. Tretli, G. Austad and T. Bjorge, Height and body mass index in relation to colorectal and gallbladder cancer in two million Norwegian men and women, Cancer Causes Control 16 (2005), 987-996. (Pubitemid 41191423)
56. S. Garrone, G. Radetti, M. Sidoti, M. Bozzola, F. Minuto and A. Barreca, Increased insulin-like growth factor (IGF)-II and IGF/IGF-binding protein ratio in prepubertal constitutionally tall children, J Clin Endocrinol Metab 87 (2002), 5455-5460. (Pubitemid 36034343)