The role of the stomach in the control of appetite and the secretion of satiation peptides

American Journal of Physiology - Endocrinology and Metabolism

Volumn 302, Issue 6, 2012, Pages 666-673

  Steinert, Robert E ^a   Meyer Gerspach, Anne C ^a   Beglinger, Christoph ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

Glucagon like peptide 1; Gut; Humans; Interactions; Small intestine

Indexed keywords

GHRELIN; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INSULIN; PEPTIDE YY; PLACEBO;

ADULT; APPETITE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; MALE; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; RANDOMIZED CONTROLLED TRIAL; SATIETY; SHORT COURSE THERAPY; SIGNAL TRANSDUCTION; STOMACH; STOMACH DISTENSION; STOMACH EMPTYING;

ADULT; APPETITE; BLOOD GLUCOSE; DOUBLE-BLIND METHOD; DUODENUM; FEMALE; GASTRIC EMPTYING; GHRELIN; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE; HUMANS; INSULIN; INTUBATION, GASTROINTESTINAL; MALE; NEUROPEPTIDES; PEPTIDE YY; SATIATION; STOMACH; YOUNG ADULT;

EID: 84858208918     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00457.2011     Document Type: Article

References (53)

1. Batterham R, Cowley M, Small C, Herzog H, Cohen M, Dakin C, Wren A, Brynes A, Low M, Ghatei M, Cone R, Bloom S. Gut hormone PYY3-36 physiologically inhibits food intake. Nature 418: 650-654, 2002.
2. Blundell J, de Graaf C, Hulshof T, Jebb S, Livingstone B, Lluch A, Mela D, Salah S, Schuring E, van der Knaap H, Westerterp M. Appetite control: methodological aspects of the evaluation of foods. Obes Rev 11: 251-270, 2010.
3. Braden B, Adams S, Duan LP, Orth KH, Maul FD, Lembcke B, Hor G, Caspary WF. The [13C]acetate breath test accurately reflects gastric emptying of liquids in both liquid and semisolid test meals. Gastroenterology 108: 1048-1055, 1995.
4. Brener W, Hendrix TR, McHugh PR. Regulation of the gastric emptying of glucose. Gastroenterology 85: 76-82, 1983.
5. Castiglione KE, Read NW, French SJ. Food intake responses to upper gastrointestinal lipid infusions in humans. Physiol Behav 64: 141-145, 1998.
6. Cecil JE, Francis J, Read NW. Relative contributions of intestinal, gastric, oro-sensory influences and information to changes in appetite induced by the same liquid meal. Appetite 31: 377-390, 1998.
7. Chaikomin R, Doran S, Jones KL, Feinle-Bisset C, O'Donovan D, Rayner CK, Horowitz M. Initially more rapid small intestinal glucose delivery increases plasma insulin, GIP, and GLP-1 but does not improve overall glycemia in healthy subjects. Am J Physiol Endocrinol Metab 289: E504-E507, 2005.
8. Cummings D, Overduin J. Gastrointestinal regulation of food intake. J Clin Invest 117: 13-23, 2007.
9. Degen L, Oesch S, Matzinger D, Drewe J, Knupp M, Zimmerli F, Beglinger C. Effects of a preload on reduction of food intake by GLP-1 in healthy subjects. Digestion 74: 78-84, 2006.
10. Deutsch JA. The role of the stomach in eating. Am J Clin Nutr 42: 1040-1043, 1985.
11. Feinle C, Grundy D, Fried M. Modulation of gastric distension-induced sensations by small intestinal receptors. Am J Physiol Gastrointest Liver Physiol 280: G51-G57, 2001.
12. Feinle C, Grundy D, Read NW. Effects of duodenal nutrients on sensory and motor responses of the human stomach to distension. Am J Physiol Gastrointest Liver Physiol 273: G721-G726, 1997.
13. French SJ, Cecil JE. Oral, gastric and intestinal influences on human feeding. Physiol Behav 74: 729-734, 2001.
14. Geliebter A, Westreich S, Gage D. Gastric distention by balloon and test-meal intake in obese and lean subjects. Am J Clin Nutr 48: 592-594, 1988.
15. Gerspach AC, Steinert RE, Schönenberger L, Graber-Maier A, Beglinger C. The role of the gut sweet taste receptor in regulating GLP-1, PYY, and CCK release in humans. Am J Physiol Endocrinol Metab 301: E317-E325, 2011.
16. Ghoos YF, Maes BD, Geypens BJ, Mys G, Hiele MI, Rutgeerts PJ, Vantrappen G. Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test. Gastroenterology 104: 1640-1647, 1993.
17. Gibbs J, Young R, Smith G. Cholecystokinin decreases food intake in rats. J Comp Physiol Psychol 84: 488-495, 1973.
18. Goetze O, Steingoetter A, Menne D, van der Voort IR, Kwiatek MA, Boesiger P, Weishaupt D, Thumshirn M, Fried M, Schwizer W. The effect of macronutrients on gastric volume responses and gastric emptying in humans: A magnetic resonance imaging study. Am J Physiol Gastrointest Liver Physiol 292: G11-G17, 2007.
19. Gutzwiller J, Göke B, Drewe J, Hildebrand P, Ketterer S, Handschin D, Winterhalder R, Conen D, Beglinger C. Glucagon-like peptide-1: a potent regulator of food intake in humans. Gut 44: 81-86, 1999.
20. Horowitz M, Edelbroek MA, Wishart JM, Straathof JW. Relationship between oral glucose tolerance and gastric emptying in normal healthy subjects. Diabetologia 36: 857-862, 1993.
21. Hunt JN, Smith JL, Jiang CL. Effect of meal volume and energy density on the gastric emptying of carbohydrates. Gastroenterology 89: 1326-1330, 1985.
22. Hunt JN, Stubbs DF. The volume and energy content of meals as determinants of gastric emptying. J Physiol 245: 209-225, 1975.
23. Kaplan J, Spector A, Grill H. Dynamics of gastric emptying during and after stomach fill. Am J Physiol Regul Integr Comp Physiol 263: R813-R819, 1992.
24. Kaplan JM, Siemers W, Grill HJ. Ingestion, gastric fill, and gastric emptying before and after withdrawal of gastric contents. Am J Physiol Regul Integr Comp Physiol 267: R1257-R1265, 1994.
25. Liebling DS, Eisner JD, Gibbs J, Smith GP. Intestinal satiety in rats. J Comp Physiol Psychol 89: 955-965, 1975.
26. Lieverse R, Jansen J, Masclee A, Lamers C. Satiety effects of a physiological dose of cholecystokinin in humans. Gut 36: 176-179, 1995.
27. Lin HC, Doty JE, Reedy TJ, Meyer JH. Inhibition of gastric emptying by glucose depends on length of intestine exposed to nutrient. Am J Physiol Gastrointest Liver Physiol 256: G404-G411, 1989.
28. Ma J, Pilichiewicz AN, Feinle-Bisset C, Wishart JM, Jones KL, Horowitz M, Rayner CK. Effects of variations in duodenal glucose load on glycaemic, insulin, and incretin responses in type 2 diabetes. Diabet Med. In press.
29. Matzinger D, Gutzwiller J, Drewe J, Orban A, Engel R, D'Amato M, Rovati L, Beglinger C. Inhibition of food intake in response to intestinal lipid is mediated by cholecystokinin in humans. Am J Physiol Regul Integr Comp Physiol 277: R1718-R1724, 1999.
30. Moran TH, McHugh PR. Distinctions among three sugars in their effects on gastric emptying and satiety. Am J Physiol Regul Integr Comp Physiol 241: R25-R30, 1981.
31. Moran TH, McHugh PR. Gastric and nongastric mechanisms for satiety action of cholecystokinin. Am J Physiol Regul Integr Comp Physiol 254: R628-R632, 1988.
32. Moran TH, Wirth JB, Schwartz GJ, McHugh PR. Interactions between gastric volume and duodenal nutrients in the control of liquid gastric emptying. Am J Physiol Regul Integr Comp Physiol 276: R997-R1002, 1999.
33. Muurahainen N, Kissileff H, Lachaussée J, Pi-Sunyer F. Effect of a soup preload on reduction of food intake by cholecystokinin in humans. Am J Physiol Regul Integr Comp Physiol 260: R672-R680, 1991.
34. O'Donovan DG, Doran S, Feinle-Bisset C, Jones KL, Meyer JH, Wishart JM, Morris HA, Horowitz M. Effect of variations in small intestinal glucose delivery on plasma glucose, insulin, and incretin hormones in healthy subjects and type 2 diabetes. J Clin Endocrinol Metab 89: 3431-3435, 2004.
35. Oesch S, Degen L, Beglinger C. Effect of a protein preload on food intake and satiety feelings in response to duodenal fat perfusions in healthy male subjects. Am J Physiol Regul Integr Comp Physiol 289: R1042-R1047, 2005.
36. Oesch S, Rüegg C, Fischer B, Degen L, Beglinger C. Effect of gastric distension prior to eating on food intake and feelings of satiety in humans. Physiol Behav 87: 903-910, 2006.
37. Park MI, Camilleri M. Gastric motor and sensory functions in obesity. Obes Res 13: 491-500, 2005.
38. Parker BA, Doran S, Wishart J, Horowitz M, Chapman IM. Effects of small intestinal and gastric glucose administration on the suppression of plasma ghrelin concentrations in healthy older men and women. Clin Endocrinol (Oxf) 62: 539-546, 2005.
39. Peterli R, Wölnerhanssen B, Peters T, Devaux N, Kern B, Christoffel-Courtin C, Drewe J, von Flüe M, Beglinger C. Improvement in glucose metabolism after bariatric surgery: comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: a prospective randomized trial. Ann Surg 250: 234-241, 2009.
40. Phillips R, Powley T. Gastric volume rather than nutrient content inhibits food intake. Am J Physiol Regul Integr Comp Physiol 271: R766-R769, 1996.
41. Pilichiewicz AN, Chaikomin R, Brennan IM, Wishart JM, Rayner CK, Jones KL, Smout AJ, Horowitz M, Feinle-Bisset C. Load-dependent effects of duodenal glucose on glycemia, gastrointestinal hormones, antropyloroduodenal motility, and energy intake in healthy men. Am J Physiol Endocrinol Metab 293: E743-E753, 2007.
42. Powley TL, Phillips RJ. Gastric satiation is volumetric, intestinal satiation is nutritive. Physiol Behav 82: 69-74, 2004.
43. Rolls BJ, Castellanos VH, Halford JC, Kilara A, Panyam D, Pelkman CL, Smith GP, Thorwart ML. Volume of food consumed affects satiety in men. Am J Clin Nutr 67: 1170-1177, 1998.
44. Schirra J, Katschinski M, Weidmann C, Schäfer T, Wank U, Arnold R, Göke B. Gastric emptying and release of incretin hormones after glucose ingestion in humans. J Clin Invest 97: 92-103, 1996.
45. Schwartz GJ, McHugh PR, Moran TH. Gastric loads and cholecystokinin synergistically stimulate rat gastric vagal afferents. Am J Physiol Regul Integr Comp Physiol 265: R872-R876, 1993.
46. Steinert RE, Poller B, Castelli MC, Friedman K, Huber AR, Drewe J, Beglinger C. Orally administered glucagon-like peptide-1 affects glucose homeostasis following an oral glucose tolerance test in healthy male subjects. Clin Pharmacol Ther 86: 644-650, 2009.
47. Tschop M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature 407: 908-913, 2000.
48. Vazquez Roque MI, Camilleri M, Stephens DA, Jensen MD, Burton DD, Baxter KL, Zinsmeister AR. Gastric sensorimotor functions and hormone profile in normal weight, overweight, and obese people. Gastroenterology 131: 1717-1724, 2006.
49. Welch I, Saunders K, Read N. Effect of ileal and intravenous infusions of fat emulsions on feeding and satiety in human volunteers. Gastroenterology 89: 1293-1297, 1985.
50. Welch IM, Sepple CP, Read NW. Comparisons of the effects on satiety and eating behaviour of infusion of lipid into the different regions of the small intestine. Gut 29: 306-311, 1988.
51. Williams DL, Cummings DE, Grill HJ, Kaplan JM. Meal-related ghrelin suppression requires postgastric feedback. Endocrinology 144: 2765-2767, 2003.
52. Wirth JB, McHugh PR. Gastric distension and short-term satiety in the rhesus monkey. Am J Physiol Regul Integr Comp Physiol 245: R174-R180, 1983.
53. Wren AM, Seal LJ, Cohen MA, Brynes AE, Frost GS, Murphy KG, Dhillo WS, Ghatei MA, Bloom SR. Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab 86: 5992, 2001.