메뉴 건너뛰기




Volumn 47, Issue 3, 2012, Pages 540-550

N-acetylcysteine may prevent severe intestinal damage in necrotizing enterocolitis

Author keywords

N acetylcysteine; Necrotizing enterocolitis; Newborn; Protection; Rat

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CASPASE 8; CASPASE 9; MALONALDEHYDE; MYELOPEROXIDASE; XANTHINE OXIDASE;

EID: 84858204253     PISSN: 00223468     EISSN: 15315037     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2011.09.051     Document Type: Article
Times cited : (22)

References (47)
  • 1
    • 78751625682 scopus 로고    scopus 로고
    • Necrotizing enterocolitis
    • N. Josef, and W.A. Walker Necrotizing enterocolitis N Engl J Med 364 2011 255 264
    • (2011) N Engl J Med , vol.364 , pp. 255-264
    • Josef, N.1    Walker, W.A.2
  • 2
    • 40749116798 scopus 로고    scopus 로고
    • Necrotizing Enterocolitis: Recent Scientific Advances in Pathophysiology and Prevention
    • DOI 10.1053/j.semperi.2008.01.004, PII S0146000508000050
    • P.W. Lin, T.R. Nasr, and B.J. Stoll Necrotizing enterocolitis: recent scientific advances in pathophysiology and prevention Semin Perinatol 32 2008 70 82 (Pubitemid 351381166)
    • (2008) Seminars in Perinatology , vol.32 , Issue.2 , pp. 70-82
    • Lin, P.W.1    Nasr, T.R.2    Stoll, B.J.3
  • 3
    • 63449128883 scopus 로고    scopus 로고
    • Necrotizing enterocolitis: Etiology, presentation, management, and outcomes
    • W.T. Bradshaw Necrotizing enterocolitis: etiology, presentation, management, and outcomes J Perinat Neonatal Nurs 23 2009 87 94
    • (2009) J Perinat Neonatal Nurs , vol.23 , pp. 87-94
    • Bradshaw, W.T.1
  • 4
    • 44949138568 scopus 로고    scopus 로고
    • Necrotizing enterocolitis in newborns: Pathogenesis, prevention and management
    • DOI 10.2165/00003495-200868090-00004
    • A.M. Thompson, and M.J. Bizzarro Necrotizing enterocolitis in newborns: pathogenesis, prevention and management Drugs 68 2008 1227 1238 (Pubitemid 351822112)
    • (2008) Drugs , vol.68 , Issue.9 , pp. 1227-1238
    • Thompson, A.M.1    Bizzarro, M.J.2
  • 5
    • 63549098010 scopus 로고    scopus 로고
    • Current concepts regarding the pathogenesis of necrotizing enterocolitis
    • M. Petrosyan, Y.S. Guner, and M. Williams Current concepts regarding the pathogenesis of necrotizing enterocolitis Pediatr Surg Int 25 2009 309 318
    • (2009) Pediatr Surg Int , vol.25 , pp. 309-318
    • Petrosyan, M.1    Guner, Y.S.2    Williams, M.3
  • 6
    • 34347398019 scopus 로고    scopus 로고
    • Treatment outcomes of necrotizing enterocolitis for preterm infants
    • B.M. Carter Treatment outcomes of necrotizing enterocolitis for preterm infants J Obstet Gynecol Neonatal Nurs 36 2007 377 384
    • (2007) J Obstet Gynecol Neonatal Nurs , vol.36 , pp. 377-384
    • Carter, B.M.1
  • 7
    • 0033011296 scopus 로고    scopus 로고
    • Relevance of N-acetylcysteine in clinical practice: Fact, myth or consequence?
    • DOI 10.1016/S0899-9007(98)00060-4, PII S0899900798000604
    • J. Faintuch, P.B. Aguilar, and W. Nadalin Relevance of N-acetylcysteine in clinical practice: fact, myth or consequence? Nutrition 15 1999 177 179 (Pubitemid 29072671)
    • (1999) Nutrition , vol.15 , Issue.2 , pp. 177-179
    • Faintuch, J.1    Aguilar, P.B.2    Nadalin, W.3
  • 8
    • 8844226799 scopus 로고    scopus 로고
    • The effect of N-acetylcysteine on oxidative stress in intestine and bacterial translocation after thermal injury
    • DOI 10.1016/j.burns.2004.05.006, PII S0305417904001330
    • K. Ocal, D. Avlan, and I. Cinel The effect of N-acetylcysteine on oxidative stress in intestine and bacterial translocation after thermal injury Burns 30 2004 778 784 (Pubitemid 39536043)
    • (2004) Burns , vol.30 , Issue.8 , pp. 778-784
    • Ocal, K.1    Avlan, D.2    Cinel, I.3    Unlu, A.4    Ozturk, C.5    Yaylak, F.6    Dirlik, M.7    Camdeviren, H.8    Aydin, S.9
  • 9
    • 63049126144 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine on intestinal reoxygenation injury in hypoxic newborn piglets resuscitated with 100% oxygen
    • S.T. Johnson, D.L. Bigam, and M. Emara Effects of N-acetylcysteine on intestinal reoxygenation injury in hypoxic newborn piglets resuscitated with 100% oxygen Neonatology 96 2009 162 170
    • (2009) Neonatology , vol.96 , pp. 162-170
    • Johnson, S.T.1    Bigam, D.L.2    Emara, M.3
  • 10
    • 33846859102 scopus 로고    scopus 로고
    • N-acetylcysteine improves intestinal barrier in partially hepatectomized rats
    • DOI 10.1111/j.1445-2197.2006.04001.x
    • S. Oz, E. Okay, and A. Karadenizli N-acetylcysteine improves intestinal barrier in partially hepatectomized rats ANZ J Surg 77 2007 173 176 (Pubitemid 46221086)
    • (2007) ANZ Journal of Surgery , vol.77 , Issue.3 , pp. 173-176
    • Oz, S.1    Okay, E.2    Karadenizli, A.3    Cekmen, M.B.4    Ozdogan, H.K.5
  • 12
    • 58149295859 scopus 로고    scopus 로고
    • Assessment of a neonatal rat model of necrotizing enterocolitis
    • A. Zani, L. Cordischi, and M. Cananzi Assessment of a neonatal rat model of necrotizing enterocolitis Eur J Pediatr Surg 18 2008 423 426
    • (2008) Eur J Pediatr Surg , vol.18 , pp. 423-426
    • Zani, A.1    Cordischi, L.2    Cananzi, M.3
  • 13
    • 0028020174 scopus 로고
    • Role of asphyxia and feeding in a neonatal rat model of necrotizing enterocolitis
    • M.S. Caplan, E. Hedlund, and L. Adler Role of asphyxia and feeding in a neonatal rat model of necrotizing enterocolitis Pediatr Pathol 14 1994 1017 1028 (Pubitemid 24357149)
    • (1994) Pediatric Pathology , vol.14 , Issue.6 , pp. 1017-1028
    • Caplan, M.S.1    Hedlund, E.2    Adler, L.3    Hsueh, W.4
  • 14
    • 1642447868 scopus 로고    scopus 로고
    • Intestinal Epithelial Apoptosis Initiates Gross Bowel Necrosis in an Experimental Rat Model of Neonatal Necrotizing Enterocolitis
    • DOI 10.1203/01.PDR.0000113463.70435.74
    • T. Jilling, J. Lu, and M. Jackson Intestinal epithelial apoptosis initiates gross bowel necrosis in an experimental rat model of neonatal necrotizing enterocolitis Pediatr Res 55 2004 622 629 (Pubitemid 38405849)
    • (2004) Pediatric Research , vol.55 , Issue.4 , pp. 622-629
    • Jilling, T.1    Lu, J.2    Jackson, M.3    Caplan, M.S.4
  • 15
    • 71449107256 scopus 로고    scopus 로고
    • Oxidant stress due to non-ionic low osmolar contrast medium in rat kidney
    • E. Devrim, M. Çetin, and M. Namuslu Oxidant stress due to non-ionic low osmolar contrast medium in rat kidney Indian J Med Res 130 2009 433 436
    • (2009) Indian J Med Res , vol.130 , pp. 433-436
    • Devrim, E.1    Çetin, M.2    Namuslu, M.3
  • 16
    • 71849104860 scopus 로고
    • Protein measurement with the folin phenol reagent
    • O.H. Lowry, N.J. Rosebrough, and A.L. Farr Protein measurement with the folin phenol reagent J Biol Chem 193 1951 265 275
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.L.3
  • 17
    • 0016818865 scopus 로고
    • Malignant transformation-linked imbalance: Decreased xanthine oxidase activity in hepatomas
    • N. Prajda, and G. Weber Malignant transformation-linked imbalance: decreased xanthine oxidase activity in hepatomas FEBS Lett 59 1975 245 249
    • (1975) FEBS Lett , vol.59 , pp. 245-249
    • Prajda, N.1    Weber, G.2
  • 18
    • 77954780042 scopus 로고    scopus 로고
    • Exaggerated liver injury induced by renal ischemia reperfusion in diabetes: Effect of exenatide
    • J.D. Vaghasiya, N.R. Sheth, and Y.S. Bhalodia Exaggerated liver injury induced by renal ischemia reperfusion in diabetes: effect of exenatide Saudi J Gastroenterol 16 2010 174 180
    • (2010) Saudi J Gastroenterol , vol.16 , pp. 174-180
    • Vaghasiya, J.D.1    Sheth, N.R.2    Bhalodia, Y.S.3
  • 19
    • 29144527533 scopus 로고    scopus 로고
    • A new automated colorimetric method for measuring total oxidant status
    • O. Erel A new automated colorimetric method for measuring total oxidant status Clin Biochem 38 2005 1103 1111
    • (2005) Clin Biochem , vol.38 , pp. 1103-1111
    • Erel, O.1
  • 20
    • 0025142672 scopus 로고
    • Malondialdehyde determination as index of lipid peroxidation
    • DOI 10.1016/0076-6879(90)86135-I
    • H.H. Draper, and M. Hadley Malondialdehyde determination as index of lipid peroxidation Methods Enzymol 186 1990 421 431 (Pubitemid 20279983)
    • (1990) Methods in Enzymology , vol.186 , pp. 421-431
    • Draper, H.H.1    Hadley, M.2
  • 21
    • 33749256611 scopus 로고    scopus 로고
    • Vitamin E protects against oxidative damage caused by formaldehyde in the liver and plasma of rats
    • DOI 10.1007/s11010-006-9165-z
    • M. Gulec, A. Gurel, and F. Armutcu Vitamin E protects against oxidative damage caused by formaldehyde in the liver and plasma of rats Mol Cell Biochem 290 2006 61 67 (Pubitemid 44478693)
    • (2006) Molecular and Cellular Biochemistry , vol.290 , Issue.1-2 , pp. 61-67
    • Gulec, M.1    Gurel, A.2    Armutcu, F.3
  • 22
    • 79251556899 scopus 로고    scopus 로고
    • The effect of glutamine on oxidative damage in an experimental abdominal compartment syndrome model in rats
    • D.N. Tihan, Y. Erbil, and R. Seven The effect of glutamine on oxidative damage in an experimental abdominal compartment syndrome model in rats Ulus Travma Acil Cerrahi Derg 17 2011 1 8
    • (2011) Ulus Travma Acil Cerrahi Derg , vol.17 , pp. 1-8
    • Tihan, D.N.1    Erbil, Y.2    Seven, R.3
  • 23
    • 15244361254 scopus 로고    scopus 로고
    • Epidermal growth factor reduces intestinal apoptosis in an experimental model of necrotizing enterocolitis
    • J.A. Clark, R.H. Lane, and N.K. Maclennan Epidermal growth factor reduces intestinal apoptosis in an experimental model of necrotizing enterocolitis Am J Physiol Gastrointest Liver Physiol 288 2005 755 762
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.288 , pp. 755-762
    • Clark, J.A.1    Lane, R.H.2    MacLennan, N.K.3
  • 24
    • 73549100466 scopus 로고    scopus 로고
    • Neonatal necrotizing enterocolitis-inflammation and intestinal immaturity
    • E.C. Claud Neonatal necrotizing enterocolitis-inflammation and intestinal immaturity Antiinflamm Antiallergy Agents Med Chem 8 2009 248 259
    • (2009) Antiinflamm Antiallergy Agents Med Chem , vol.8 , pp. 248-259
    • Claud, E.C.1
  • 25
    • 38349138320 scopus 로고    scopus 로고
    • Understanding the susceptibility of the premature infant to necrotizing enterocolitis (NEC)
    • C.J. Hunter, J.S. Upperman, and H.R. Ford Understanding the susceptibility of the premature infant to necrotizing enterocolitis (NEC) Pediatr Res 63 2008 117 123
    • (2008) Pediatr Res , vol.63 , pp. 117-123
    • Hunter, C.J.1    Upperman, J.S.2    Ford, H.R.3
  • 26
    • 53149118993 scopus 로고    scopus 로고
    • Bacterial colonization, probiotics, and necrotizing enterocolitis
    • E.C. Claud, and W.A. Walker Bacterial colonization, probiotics, and necrotizing enterocolitis J Clin Gastroenterol 42 2008 S46 S52
    • (2008) J Clin Gastroenterol , vol.42
    • Claud, E.C.1    Walker, W.A.2
  • 27
    • 40749100118 scopus 로고    scopus 로고
    • The Neonatal Intestinal Vasculature: Contributing Factors to Necrotizing Enterocolitis
    • DOI 10.1053/j.semperi.2008.01.003, PII S0146000508000049
    • C.A. Nankervis, P.J. Giannone, and K.M. Reber The neonatal intestinal vasculature: contributing factors to necrotizing enterocolitis Semin Perinatol 32 2008 83 91 (Pubitemid 351381165)
    • (2008) Seminars in Perinatology , vol.32 , Issue.2 , pp. 83-91
    • Nankervis, C.A.1    Giannone, P.J.2    Reber, K.M.3
  • 28
    • 77951621050 scopus 로고    scopus 로고
    • Mesenteric nitric oxide and superoxide production in experimental necrotizing enterocolitis
    • J.S. Whitehouse, H. Xu, and Y. Shi Mesenteric nitric oxide and superoxide production in experimental necrotizing enterocolitis J Surg Res 161 2010 1 8
    • (2010) J Surg Res , vol.161 , pp. 1-8
    • Whitehouse, J.S.1    Xu, H.2    Shi, Y.3
  • 29
    • 73449140783 scopus 로고    scopus 로고
    • N-acetylcysteine improves disturbed ileal contractility following partial hepatectomy in rats
    • E. Okay, O. Mutlu, and S.S. Gocmez N-acetylcysteine improves disturbed ileal contractility following partial hepatectomy in rats J Gastroenterol Hepatol 25 2010 203 208
    • (2010) J Gastroenterol Hepatol , vol.25 , pp. 203-208
    • Okay, E.1    Mutlu, O.2    Gocmez, S.S.3
  • 32
    • 79953892976 scopus 로고    scopus 로고
    • Future applications of antioxidants in premature infants
    • W.L. Jennifer, and J.M. Davis Future applications of antioxidants in premature infants Curr Opin Pediatr 22 2011 161 166
    • (2011) Curr Opin Pediatr , vol.22 , pp. 161-166
    • Jennifer, W.L.1    Davis, J.M.2
  • 33
    • 62849084588 scopus 로고    scopus 로고
    • The effects of N-acetylcysteine on intestinal ischemia/reperfusion injury in rats
    • S. Ayvaz, B. Aksu, and M. Inan The effects of N-acetylcysteine on intestinal ischemia/reperfusion injury in rats Saudi Med J 30 2009 24 29
    • (2009) Saudi Med J , vol.30 , pp. 24-29
    • Ayvaz, S.1    Aksu, B.2    Inan, M.3
  • 35
    • 0030859188 scopus 로고    scopus 로고
    • The effects of intravenous antioxidants in patients with septic shock
    • DOI 10.1016/S0891-5849(97)00059-2, PII S0891584997000592
    • H.F. Galley, P.D. Howdle, and B.E. Walker The effect of intravenous antioxidants in patients with septic shock Free Radic Biol Med 23 1997 768 774 (Pubitemid 27364871)
    • (1997) Free Radical Biology and Medicine , vol.23 , Issue.5 , pp. 768-774
    • Galley, H.F.1    Howdle, P.D.2    Walker, B.E.3    Webster, N.R.4
  • 36
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • DOI 10.1016/0003-2697(79)90738-3
    • H. Okhawa, N. Ohishi, and K. Yagi Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Ann Biochem 95 1979 351 358 (Pubitemid 9194347)
    • (1979) Analytical Biochemistry , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 37
    • 77649182470 scopus 로고    scopus 로고
    • Microecology, intestinal epithelial barrier and necrotizing enterocolitis
    • R. Sharma, and J.J. Tepas III Microecology, intestinal epithelial barrier and necrotizing enterocolitis Pediatr Surg Int 26 2010 11 21
    • (2010) Pediatr Surg Int , vol.26 , pp. 11-21
    • Sharma, R.1    Tepas Iii, J.J.2
  • 38
    • 0035007355 scopus 로고    scopus 로고
    • Hypothesis: Inappropriate colonization of the premature intestine can cause neonatal necrotizing enterocolitis
    • DOI 10.1096/fj.00-0833hyp
    • E.C. Claud, and W.A. Walker Hypothesis: inappropriate colonization of the premature intestine can cause neonatal necrotizing enterocolitis FASEB J 15 2001 1398 1403 (Pubitemid 32531817)
    • (2001) FASEB Journal , vol.15 , Issue.8 , pp. 1398-1403
    • Claud, E.C.1    Walker, W.A.2
  • 39
    • 0032950419 scopus 로고    scopus 로고
    • Effects of bucillamine and N-acetyl-L-cysteine on cytokine production and collagen-induced arthritis (CIA)
    • DOI 10.1046/j.1365-2249.1999.00749.x
    • F. Tsuji, Y. Miyake, and H. Aono Effects of bucillamine and N-acetylcysteine on cytokine production and collagen-induced arthritis Clin Exp Immunol 115 1999 26 31 (Pubitemid 29030360)
    • (1999) Clinical and Experimental Immunology , vol.115 , Issue.1 , pp. 26-31
    • Tsuji, F.1    Miyake, Y.2    Aono, H.3    Kawashima, Y.4    Mita, S.5
  • 40
    • 0033106338 scopus 로고    scopus 로고
    • N-acetyl-L-cysteine inhibits primary human T cell responses at the dendritic cell level: Association with NF-κB inhibition
    • V. Verhasselt, W. Vanden Berghe, and N. Vanderheyde N-acetylcysteine inhibits primary human T cell responses at the dendritic cell level: association with NF-B inhibition J Immunol 162 1999 2569 2574 (Pubitemid 29309275)
    • (1999) Journal of Immunology , vol.162 , Issue.5 , pp. 2569-2574
    • Verhasselt, V.1    Vanden Berghe, W.2    Vanderheyde, N.3    Willems, F.4    Haegeman, G.5    Goldman, M.6
  • 42
    • 0038113408 scopus 로고    scopus 로고
    • The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model
    • A. Ozdulger, I. Cinel, and O. Koksel The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model Shock 19 2003 366 372
    • (2003) Shock , vol.19 , pp. 366-372
    • Ozdulger, A.1    Cinel, I.2    Koksel, O.3
  • 44
    • 79955906531 scopus 로고    scopus 로고
    • N-acetylcysteine in handgrip exercise: Plasma thiols and adverse reactions
    • L.F. Ferreira, K.S. Campbell, and M.B. Reid N-acetylcysteine in handgrip exercise: plasma thiols and adverse reactions Int J Sport Nutr Exerc Metab 21 2011 146 154
    • (2011) Int J Sport Nutr Exerc Metab , vol.21 , pp. 146-154
    • Ferreira, L.F.1    Campbell, K.S.2    Reid, M.B.3
  • 45
    • 69149098551 scopus 로고    scopus 로고
    • N-acetylcysteine: Multiple clinical applications
    • P.J. Millea N-acetylcysteine: multiple clinical applications Am Fam Physician 80 2009 265 269
    • (2009) Am Fam Physician , vol.80 , pp. 265-269
    • Millea, P.J.1
  • 46
    • 33846677487 scopus 로고    scopus 로고
    • Acetaminophen-induced hepatic failure with encephalopathy in a newborn
    • DOI 10.1038/sj.jp.7211641, PII 7211641
    • L. Walls, C.F. Baker, and S. Sarkar Acetaminophen-induced hepatic failure with encephalopathy in a newborn J Perinatol 27 2007 133 135 (Pubitemid 46195916)
    • (2007) Journal of Perinatology , vol.27 , Issue.2 , pp. 133-135
    • Walls, L.1    Baker, C.F.2    Sarkar, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.