Pharmacokinetics and pharmacodynamics of intraperitoneal cancer chemotherapeutics

Clinical Pharmacokinetics

Volumn 51, Issue 4, 2012, Pages 203-224

  Hasovits, Csilla ^a   Clarke, Stephen ^a,b  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Antineoplastics; Cancer; Intraperitoneal; Pharmacokinetics; Pharmacology.

Indexed keywords

AMINOTRANSFERASE; ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; CREATININE; CYTARABINE; DIPYRIDAMOLE; DOCETAXEL; DOXORUBICIN; ETOPOSIDE; FLOXURIDINE; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; GIMERACIL PLUS OTERACIL POTASSIUM PLUS TEGAFUR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IRINOTECAN; MELPHALAN; METHOTREXATE; MITOMYCIN; MITOXANTRONE; OXALIPLATIN; PACLITAXEL; PEMETREXED; SODIUM THIOSULFATE; THIOTEPA; TOPOTECAN; UNINDEXED DRUG; VASOPRESSIN; VINBLASTINE;

ABDOMINAL ABSCESS; ABDOMINAL PAIN; ADENOCARCINOMA; ALOPECIA; ANEMIA; AREA UNDER THE CURVE; ARTHRALGIA; BACTERIAL PERITONITIS; BLOOD TOXICITY; BONE MARROW SUPPRESSION; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER MORTALITY; CANCER OF UNKNOWN PRIMARY SITE; CANCER RELAPSE; CANCER SURVIVAL; CARCINOMATOUS PERITONITIS; CHILL; COLON CANCER; COLORECTAL CANCER; CONSOLIDATION CHEMOTHERAPY; CREATININE BLOOD LEVEL; DIARRHEA; DIGESTIVE SYSTEM CANCER; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG DOSE REDUCTION; DRUG FATALITY; DRUG FEVER; DRUG MEGADOSE; DRUG METABOLISM; DRUG PENETRATION; DRUG SAFETY; DRUG SOLUBILITY; DRUG SUBSTITUTION; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; DYSPNEA; ENDOMETRIUM CANCER; FATIGUE; FEBRILE NEUTROPENIA; FIRST PASS EFFECT; GASTROINTESTINAL SYMPTOM; GRANULOCYTOPENIA; HEARING LOSS; HUMAN; HYPERTENSION; HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY; HYPERTHERMIC THERAPY; HYPOMAGNESEMIA; INFECTION; INTESTINE OBSTRUCTION; INTRAPERITONEAL DRUG ADMINISTRATION; LAPAROSCOPY; LEIOMYOSARCOMA; LEUKOPENIA; LIVER DYSFUNCTION; LIVER TOXICITY; MEDICAL LITERATURE; MESOTHELIOMA; MICROCIRCULATION; MORBIDITY; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; MYALGIA; NAUSEA; NAUSEA AND VOMITING; NEPHROTOXICITY; NEUROTOXICITY; NEUTROPENIA; NEUTROPENIC SEPSIS; NONHUMAN; OTOTOXICITY; OVARY CANCER; OVERALL SURVIVAL; PAIN; PANCREAS CANCER; PANCYTOPENIA; PERITONEAL CAVITY; PERITONEUM CANCER; PERITONEUM MESOTHELIOMA; PERITONEUM METASTASIS; PERITONEUM PSEUDOMYXOMA; PERITONITIS; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); POSTOPERATIVE CARE; PRIMARY TUMOR; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RARE DISEASE; RESPIRATORY FAILURE; REVIEW; SENSORY NEUROPATHY; SEPSIS; SIDE EFFECT; STOMACH CANCER; STOMATITIS; SYSTEMATIC REVIEW; THROMBOCYTOPENIA; TINNITUS; TREATMENT OUTCOME; TUMOR VASCULARIZATION; UTERINE CERVIX CANCER; UTERINE TUBE TUMOR; UTERUS CANCER; VOMITING;

ANIMALS; ANTINEOPLASTIC AGENTS; COLORECTAL NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; INJECTIONS, INTRAPERITONEAL; NEOPLASM SEEDING; OVARIAN NEOPLASMS; PERITONEAL NEOPLASMS; STOMACH NEOPLASMS;

EID: 84858195784     PISSN: 03125963     EISSN: 11791926     Source Type: Journal    
DOI: 10.2165/11598890-000000000-00000     Document Type: Review

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