Phase i study of intraperitoneal irinotecan in patients with gastric adenocarcinoma with peritoneal seeding

Cancer Chemotherapy and Pharmacology

Volumn 67, Issue 1, 2011, Pages 5-11

  Choi, Moon Ki ^a   Ahn, Byung Jin ^b   Yim, Dong Seok ^c   Park, Young Suk ^a   Kim, Sung ^a   Sohn, Tae Sung ^a   Noh, Jae Hyung ^a   Heo, Jin Seok ^a   Lee, Jeeyun ^a   Park, Se Hoon ^a   Park, Joon Oh ^a   Lim, Ho Yeong ^a   Kang, Won Ki ^a  

^a Sungkyunkwan University   (South Korea)

^b Dongguk University   (South Korea)

^c The Catholic University of Korea   (South Korea)

Author keywords

Gastric adenocarcinoma; Intraperitoneal administration; Irinotecan; Peritoneal seeding

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; IRINOTECAN;

ADULT; ANEMIA; AREA UNDER THE CURVE; ARTICLE; CANCER PALLIATIVE THERAPY; CANCER SURVIVAL; CLINICAL ARTICLE; DIARRHEA; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG TOLERABILITY; FEBRILE NEUTROPENIA; GASTRECTOMY; GASTRECTOMY BILLROTH I; GASTRECTOMY BILLROTH II; HUMAN; MAXIMUM PLASMA CONCENTRATION; MAXIMUM TOLERATED DOSE; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUTROPENIA; OVERALL SURVIVAL; PERITONEUM METASTASIS; PHASE 1 CLINICAL TRIAL; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RECOMMENDED DRUG DOSE; REPEATED DRUG DOSE; STOMACH ADENOCARCINOMA; THROMBOCYTOPENIA; TIME TO MAXIMUM PLASMA CONCENTRATION; TUMOR SEEDING; VOMITING;

ADENOCARCINOMA; ADULT; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; DIARRHEA; DISEASE-FREE SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FEVER; FOLLOW-UP STUDIES; GASTRECTOMY; HUMANS; INFUSIONS, PARENTERAL; MALE; MAXIMUM TOLERATED DOSE; MIDDLE AGED; NEUTROPENIA; PERITONEAL DIALYSIS, CONTINUOUS AMBULATORY; PERITONEAL NEOPLASMS; STOMACH NEOPLASMS;

EID: 78651113497     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-010-1272-6     Document Type: Article

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