Shilajit: A natural phytocomplex with potential procognitive activity

International Journal of Alzheimer's Disease

Volumn , Issue , 2012, Pages

  Carrasco Gallardo, Carlos ^a   Guzmán, Leonardo ^a   MacCioni, Ricardo B ^a  

^a UNIVERSITY OF CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

FULVIC ACID; SHILAJEET;

ALZHEIMER DISEASE; COGNITIVE DEFECT; DIET SUPPLEMENTATION; PRIORITY JOURNAL; REVIEW;

EID: 84858191810     PISSN: None     EISSN: 20900252     Source Type: Journal    
DOI: 10.1155/2012/674142     Document Type: Review

References (33)

1. Cornejo A., Jiménez J. M., Caballero L., Melo F., Maccioni R. B., Fulvic acid inhibits aggregation and promotes disassembly of tau fibrils associated with alzheimer's disease Journal of Alzheimer's Disease 2011 27 1 143 153
2. Ghosal S., Chemistry of shilajit, an immunomodulatory Ayurvedic rasayan Pure and Applied Chemistry 1990 62 7 1285 1288
3. N. Chopra R., C. Chopra I., L. Handa K., D. Kapoor K., In Indigenous Drugs of India 1958 Calcutta, India U.N. Dhar Sons
4. Agarwal S. P., Khanna R., Karmarkar R., Anwer M. K., Khar R. K., Shilajit: a review Phytotherapy Research 2007 21 5 401 405 (Pubitemid 46715076)
5. Ghosal S., Reddy J. P., Lal V. K., Shilajit I: chemical constituents Journal of Pharmaceutical Sciences 1976 65 5 772 773
6. Khanna R., Witt M., Khalid Anwer M., Agarwal S. P., Koch B. P., Spectroscopic characterization of fulvic acids extracted from the rock exudate shilajit Organic Geochemistry 2008 39 12 1719 1724
7. Mittal P., Kaushik D., Gupta V., Bansal P., Khokra S., Therapeutic potencial of Shilajit RasayanaA Review International Journal of Pharmaceutical and Clinical Research 2009 1 2 47 49
8. M. S. Islam K., Schumacher A., M. Gropp J., Humic acid substances in animal agriculture Pakistan Journal of Nutrition 2005 4 126 134
9. Vucskits A. V., Hullr I., Bersényi A., Andrsofszky E., Kulcsr M., Szab J., Effect of fulvic and humic acids on performance, immune response and thyroid function in rats Journal of Animal Physiology and Animal Nutrition 2010 94 6 721 728
10. Schepetkin I. A., Xie G., Jutila M. A., Quinn M. T., Complement-fixing activity of fulvic acid from shilajit and other natural sources Phytotherapy Research 2009 23 3 373 384
11. Kong Y. C., But P. P. H., Ng K. H., Chemical studies on a Nepalese Panacea shilajit (I) International Journal of Crude Drug Research 1987 25 3 179 182 (Pubitemid 17138081)
12. Ghosal S., Lal J., Singh S. K., Goel R. K., Jaiwal A. K., Bhattacharya S. K., The need for formulation of shilajit by its isolated active constituents Phytotherapy Research 1991 5 5 211 216
13. Ghosal S., Mukherjee B., K. Bhattacharya S., Shilajit a comparative study of the ancient and the modern scientific findings Indian Journal of Indigenous Medicine 1995 17 1 10
14. Ghosal S., Singh S. K., Kumar Y., Srivastava R., Goel R. K., Dey R., Bhattacharya S. K., Shilajit. 3. Antiulcerogenic of fulvic acids and 4-methoxy-6-carbomethoxybiphenyl isolated from shilaji Phytotherapy Research 1988 2 4 187 191 (Pubitemid 19038349)
15. Ghosal S., Lata S., Kumar Y., Gaur B., Misra N., Interaction of shilajit with biogenic free radicals Indian Journal of Chemistry B 1995 34 596 602
16. Bhattacharya S. K., Sen A. P., Effects of shilajit on biogenic free radicals Phytotherapy Research 1995 9 1 56 59
17. K. Jaiswal A., K. Bhattacharya S., Effects of shilajit on memory, anxiety and brain monoamines in rats Indian Journal of Pharmacology 1992 24 12 17
18. Bhattacharya S. K., Shilajit attenuates streptozotocin induced diabetes mellitus and decrease in pancreatic islet superoxide dismutase activity in rats Phytotherapy Research 1995 9 1 41 44
19. Wang C., Wang Z., Peng A., Hou J., Xin W., Interaction between fulvic acids of different origins and active oxygen radicals Science in China, Series C 1996 39 3 267 275 (Pubitemid 126468000)
20. Ghosal S., Lal J., Singh S. K., Dasgupta G., Bhaduri J., Mukhopadhyay M., Bhattacharya S. K., Mast cell protecting effects of shilajit and its constituents Phytotherapy Research 1989 3 6 249 252 (Pubitemid 20066935)
21. Acharya S. B., Frotan M. H., Goel R. K., Tripathi S. K., Das P. K., Pharmacological actions of shilajit Indian Journal of Experimental Biology 1988 26 10 775 777 (Pubitemid 19019318)
22. Shalini, Srivastava R., Antifungal activity screening and hplc analysis of crude extract from Tectona grandis, shilajit, Valeriana wallachi Electronic Journal of Environmental, Agricultural and Food Chemistry 2009 8 4 218 229
23. Mirza M. A., Agarwal S. P., Rahman M. A., Rauf A., Ahmad N., Alam A., Iqbal Z., Role of humic acid on oral drug delivery of an antiepileptic drug Drug Development and Industrial Pharmacy 2011 37 3 310 319
24. Meena H., K. Pandey H., C. Arya M., Ahmed Z., Shilajit: a panacea for high-altitude problems International Journal of Ayurveda Research 2010 1 1 37 40
25. Wilson E., Rajamanickam G. V., Dubey G. P., Klose P., Musial F., Saha F. J., Rampp T., Michalsen A., Dobos G. J., Review on shilajit used in traditional Indian medicine Journal of Ethnopharmacology 2011 136 1 1 9
26. Rowland D., Vitamin/mineral composition. US Patent no. 5405613,1995
27. Ghosal S., Herbo-Mineral compositions. US Patent application no. 20030198695, 2002
28. Ghosal S., Process for preparing purified shilajit from native shilajit. US Patent no. 6440436, 2002
29. Ghosal S., Delivery system for pharmaceutical, nutritional and cosmetic ingredient. US Patent no. 6558712, 2003
30. B. Maccioni R., Quiones L., Saavedra I., Sandoval R., Nutraceutical composition that comprises extract of shilajit, folic acid, vitamin B12 and vitamin B6 and the use thereof for preventing and/or treating neurodegenerative disease and/or the cognitive deterioration association with cerebral aging. WO 2011/041920. PCT/CL2010/000043 April, 14. 2011
31. Saper R. B., Phillips R. S., Sehgal A., Khouri N., Davis R. B., Paquin J., Thuppil V., Kales S. N., Lead, mercury, and arsenic in US- and Indian-manufactured Ayurvedic medicines sold via the internet Journal of the American Medical Association 2008 300 8 915 923
32. Kales S. N., Saper R. B., Ayurvedic lead poisoning: an under-recognized, international problem Indian Journal of Medical Sciences 2009 63 9 379 381
33. Singh S., Mukherjee K. K., Gill K. D., Flora S. J. S., Lead-induced peripheral neuropathy following ayurvedic medication Indian Journal of Medical Sciences 2009 63 9 408 410