Using DNA damage sensitivity phenotypes to characterize mutations affecting proteasome function

Methods in Molecular Biology

Volumn 832, Issue , 2012, Pages 363-371

  Tallec, Benoît Le ^a,b   Peyroche, Anne ^a  

^a SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^b INSTITUT CURIE   (France)

Author keywords

4 Nitroquinoline 1 oxide; Camptothecin; DNA damage sensitivity; Hyperresistance; Quantitative spotting

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; 4 NITROQUINOLONE 1 OXIDE; 4-NITROQUINOLONE-1-OXIDE; ATP DEPENDENT 26S PROTEASE; CAMPTOTHECIN; CANAVANINE; MESYLIC ACID METHYL ESTER; POLYUBIQUITIN; PROTEASOME; QUINOLONE DERIVATIVE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; DNA DAMAGE; DRUG EFFECT; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; SACCHAROMYCES CEREVISIAE;

4-NITROQUINOLINE-1-OXIDE; CAMPTOTHECIN; CANAVANINE; DNA DAMAGE; METHYL METHANESULFONATE; MUTATION; POLYUBIQUITIN; PROTEASOME ENDOPEPTIDASE COMPLEX; QUINOLONES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCETALES;

EID: 84858185673     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-474-2_25     Document Type: Article

References (7)

1. Le Tallec B, Barrault MB, Courbeyrette R, et al (2007) 20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals, Mol Cell 27 , 660-674.
2. Le Tallec B, Barrault MB, Guerois R, et al (2009) Hsm3/S5b participates in the assembly pathway of the 19S regulatory particle of the proteasome. Mol Cell 33 :389-399.
3. Ornstein RL, Rein R (1980) Molecular models of induced DNA premutational damage and mutational pathways for the carcinogen 4-nitroquinoline 1-oxide and its metabolites. Chem Biol Interact 30 :87-103.
4. Pommier Y (2006) Topoisomerase I inhibitors: Camptothecins and beyond. Nat Rev Cancer 6 :789-802.
5. Wyatt MD, Pittman DL (2006) Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks. Chem Res Toxicol 19 :1580-1594.
6. London MK, Keck BI, Ramos PC, Dohmen RJ (2004) Regulatory mechanisms controlling biogenesis of ubiquitin and the proteasome. FEBS Lett 567 :259-264.
7. Ramos PC, Hockendorff J, Johnson ES, et al (1998) Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92 :489-499.