Platelet-rich plasma as a biological adjunct to the surgical treatment of osteochondral lesions of the talus

Techniques in Foot and Ankle Surgery

Volumn 11, Issue 1, 2012, Pages 18-25

  Smyth, Niall A ^a   Fansa, Ashraf M ^a   Murawski, Christopher D ^a   Kennedy, John G ^a  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

arthroscopic bone marrow stimulation; autologous osteochondral transplantation; cartilage repair; osteochondral lesion; platelet rich plasma

Indexed keywords

PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

ALLOTRANSPLANTATION; ANKLE FRACTURE; ANKLE INJURY; ANKLE SPRAIN; CARTILAGE CELL; CARTILAGE TRANSPLANTATION; CELL PROLIFERATION; CHONDROPATHY; CLINICAL DECISION MAKING; CLINICAL FEATURE; HUMAN; HYALINE CARTILAGE; INTERMETHOD COMPARISON; JOINT FUNCTION; MESENCHYMAL STEM CELL; MICROFRACTURE; NUCLEAR MAGNETIC RESONANCE IMAGING; ORTHOPEDIC SURGERY; OSTEOCHONDRAL LESIONS OF THE TALUS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REVIEW; SURGICAL TECHNIQUE; THROMBOCYTE RICH PLASMA; TREATMENT CONTRAINDICATION; TREATMENT INDICATION; TREATMENT PLANNING; UNITED STATES;

EID: 84858173213     PISSN: 15360644     EISSN: 15381943     Source Type: Journal    
DOI: 10.1097/BTF.0b013e3182463ca1     Document Type: Review

References (68)

1. Baumhauer JF, Alosa DM, Renstrom AF, et al. A propective study of ankle injury risk factors. Am J Sports Med. 1995;23:564-570.
2. Komenda GA, Ferkel RD. Arthroscopic findings associated with the unstable ankle. Foot Ankle Int. 1999;20:708-713.
3. Saxena A, Eakin C. Articular talar injuries in athletes: results of microfracture and autogenous bone graft. Am J Sports Med. 2007; 35:1680-1687. (Pubitemid 47476056)
4. Berlet G, Anderson RB, Davis W. Chronic lateral ankle instability. Foot Ankle Clin. 1999;4:713-728.
5. Harrington KD. Degenerative arthritis of the ankle secondary to long-standing lateral ligament instability. J Bone Joint Surg Am. 1979;61:354-361. (Pubitemid 9154272)
6. Chuckpaiwong B, Berkson EM, Theodore GH. Microfracture for osteochondral lesions of the ankle: outcome analysis and outcome predictors of 105 cases. Arthroscopy. 2008;24:106-112.
7. Amendola A, Panarella L. Osteochondral lesions: medial versus lateral persistent pain, cartilage restoration option and indications. Foot Ankle Clin. 2009;14:215-227.
8. Giannini S, Vannini F. Operative treatment of osteochondral lesions of the talar dome: current concepts review. Foot Ankle Int. 2004;25: 168-175. (Pubitemid 39096186)
9. Van Bergen CJ, de Leeuw PA, van Dijk CN. Treatment of osteochondral defects of the talus. Rev Chir Orthop Reparatrice Appar Mot. 2008;94:398-408.
10. Lahm A, Erggelet C, Steinwachs M, et al. Arthroscopic management of osteochondral lesions of the talus: results of drilling and usefulness of the magnetic resonance imaging before and after treatment. Arthroscopy. 2000;16:299-304. (Pubitemid 30196903)
11. Becher C, Driessen A, Hess T, et al. Microfracture for chondral defects of the talus: maintenance of early results at midterm follow-up. Knee Surg Sports Traumatol Arthrosc. 2010;18:656-663.
12. Ferkel RD, Zanotti RM, Komenda GA, et al. Arthroscopic treatment of chronic osteochondral lesions of the talus: long-term results. Am J Sports Med. 2008;36:1750-1762.
13. Murawski CD, Foo LF, Kennedy JG. A review of arthroscopic bone marrow stimulation techniques of the talus: the good,β the bad, and the causes for concern. Cartilage. 2010;1:137-144.
14. Valderrabano V, Leumann A, Rasch H, et al. Knee-to-ankle mosaicplasty for the treatment of osteochondral lesions of the ankle joint. Am J Sports Med. 2009;37(suppl 1):105S-111S.
15. Scranton PE Jr, Frey CC, Feder KS. Outcome of osteochondral autograft transplantation for type-V cystic osteochondral lesions of the talus. J Bone Joint Surg Br. 2006;88:614-619. (Pubitemid 43772943)
16. Kennedy John G, Christopher D Murawski. The treatment of osteochondral lesions of the talus with osteochondral autograft transplant (OATS): surgical technique. Cartilage. 2011;2:327-336.
17. Siebert CH, Miltner O, Schneider U, et al. Healing of osteochondral transplants-animal experiment studies using a sheep model. Z Orthop Ihre Grenzgeb. 2001;139:382-386.
18. Tibesku CO, Szuwart T, Kleffner TO, et al. Hyaline cartilage degenerates after autologous osteochondral transplantation. J Orthop Res. 2004;22:1210-1214. (Pubitemid 39317909)
19. Tasto JP, Ostrander R, Bugbee W, et al. The diagnosis and management of osteochondral lesions of the talus: osteochondral allograft update. Arthroscopy. 2003;19(suppl 1):138-141. (Pubitemid 37531953)
20. El-Rashidy H, Villacis D, Omar I, et al. Fresh osteochondral allograft for the treatment of cartilage defects of the talus: a retrospective review. J Bone Joint Surg Am. 2011;93:1634-1640.
21. Gross AE, Agnidis Z, Hutchison CR. Osteochondral defects of the talus treated with fresh osteochondral allograft transplantation. Foot Ankle Int. 2001;22:385-391. (Pubitemid 32554066)
22. Raikin SM, Stage VI. Massive osteochondral defects of the talus. Foot Ankle Clin. 2004;9:737-744. vi.
23. Miller Y, Bachowski G, Benjamin R, et al. Practice Guidelines for Blood Transfusion: a Compilation From Recent Peer-reviewed Literature. 2nd ed. Washington, DC: American Red Cross; 2007:56.
24. Cho HS, Song IH, Park SY, et al. Individual variation in growth factor concentrations in platelet-rich plasma and its influence on human mesenchymal stem cells. Korean J Lab Med. 2011; 31:212-218.
25. Smyth SS, McEver RP, Weyrich AS, et al. Platelet colloquium participants. Platelet functions beyond hemostasis. J Thromb Haemost. 2009;7:1759-1766.
26. Redini F, Galera P, Mauviel A, et al. Transforming growth factor beta stimulates collagen and glycosaminoglycan biosynthesis in cultured rabbit articular chondrocytes. FEBS Lett. 1988;234:172-176.
27. Fortier LA, Barker JU, Strauss EJ, et al. The role of growth factors in cartilage repair. Clin Orthop Relat Res. 2011;469:2706-2715.
28. Akeda K, An HS, Okuma M, et al. Platelet-rich plasma stimulates porcine articular chondrocyte proliferation and matrix biosynthesis. Osteoarthritis Cartilage. 2006;14:1272-1280. (Pubitemid 44774435)
29. Mishra A, Tummala P, King A, et al. Buffered platelet-rich plasma enhances mesenchymal stem cell proliferation and chondrogenic differentiation. Tissue Eng Part C Methods. 2009;15:431-435.
30. Sun Y, Feng Y, Zhang CQ, et al. The regenerative effect of platelet-rich plasma on healing in large osteochondral defects. Int Orthop. 2010;34:589-597.
31. Van Buul GM, Koevoet WL, Kops N, et al. Platelet-rich plasma releasate inhibits inflammatory processes in osteoarthritic chondrocytes. Am J Sports Med. 2011;39:2363-2370.
32. Easley ME, Scranton PE Jr. Osteochondral autologous transfer system. Foot Ankle Clin. 2003;8:275-290. (Pubitemid 38759126)
33. O'Loughlin PF, Heyworth BE, Kennedy JG. Current concepts in the diagnosis and treatment of osteochondral lesions of the ankle. Am J Sports Med. 2010;38:392-404.
34. Tol JL, Struijs PA, Bossuyt PM, et al. Treatment strategies in osteochondral defects of the talar dome: a systematic review. Foot Ankle Int. 2000;21:119-126. (Pubitemid 30094370)
35. Loomer R, Fisher C, Lloyd-Smith R, et al. Osteochondral lesions of the talus. Am J Sports Med. 1993;21:13-19. (Pubitemid 23026939)
36. Lusse S, Claassen H, Gehrke T, et al. Evaluation of water content by spatially resolved transverse relaxation times of human articular cartilage. Magn Reson Imaging. 2000;18:423-430. (Pubitemid 30228578)
37. Potter HG, Linklater JM, Allen AA, et al. Magnetic resonance imaging of articular cartilage in the knee. An evaluation with use of fast-spinecho imaging. J Bone Joint Surg Am. 1998;80:1276-1284. (Pubitemid 28443350)
38. Bredella MA, Tirman PF, Peterfy CG, et al. Accuracy of T2-weighted fast spin-echo MR imaging with fat saturation in detecting cartilage defects in the knee: comparison with arthroscopy in 130 patients. Am J Roentgenol. 1999;172:1073-1080. (Pubitemid 29505643)
39. Eckstein F, Westhoff J, Sittek H, et al. In vivo reproducibility of three dimensional cartilage volume and thickness measurements with MR imaging. Am J Roentgenol. 1998;170:593-597. (Pubitemid 28106642)
40. Eckstein F, Hudelmaier M, Wirth W, et al. Double echo steady state magnetic resonance imaging of knee articular cartilage at 3 Tesla: a pilot study for the Osteoarthritis Initiative. Ann Rheum Dis. 2006;65:433-441.
41. Eckstein F, Schnier M, Haubner M, et al. Accuracy of cartilage volume and thickness measurements with magnetic resonance imaging. Clin Orthop Relat Res. 1998;352:137-148. (Pubitemid 28326293)
42. Gold GE, Busse RF, Beehler C, et al. Isotropic MRI of the knee with 3D fast spin-echo extended echo-train acquisition (XETA): initial experience. Am J Roentgenol. 2007;188:1287-1293. (Pubitemid 46668510)
43. Scranton PE Jr. Osteochondral lesions of the talus: autograft and allograft replacement. Tech Foot Ankle Surg. 2004;3:25-39.
44. Guo QW, Hu YL, Jiao C, et al. Arthroscopic treatment for osteochondral lesions of the talus: analysis of outcome predictors. Chin Med J (Engl). 2010;123:296-300.
45. Ferkel RD, Fischer SP. Progress in ankle arthroscopy. Clin Orthop Relat Res. 1989;240:210-220. (Pubitemid 19072141)
46. Takao M, Uchio Y, Kakimaru H, et al. Arthroscopic drilling with debridement of remaining cartilage for osteochondral lesions of the talar dome in unstable ankles. Am J Sports Med. 2004;32: 332-336. (Pubitemid 38235499)
47. van Bergen CJ, de Leeuw PA, van Dijk CN. Potential pitfall in the microfracturing technique during the arthroscopic treatment of an osteochondral lesion. Knee Surg Sports Traumatol Arthrosc. 2009;17:184-187.
48. Nurden AT, Nurden P, Sanchez M, et al. Platelets and wound healing. Front Biosci. 2008;13:3532-3548. (Pubitemid 351594702)
49. Kurth T, Hedbom E, Shintani N, et al. Chondrogenic potential of human synovial mesenchymal stem cells in alginate. Osteoarthritis Cartilage. 2007;15:1178-1189. (Pubitemid 47387046)
50. Fan J, Gong Y, Ren L, et al. In vitro engineered cartilage using synovium-derived mesenchymal stem cells with injectable gellan hydrogels. Acta Biomater. 2010;6:1178-1185.
51. Blaney Davidson EN, van der Kraan PM, van den Berg WB. TGF-beta and osteoarthritis. Osteoarthritis Cartilage. 2007;15:597-604.
52. Bonewald LF, Mundy GR. Role of transforming growth factor-beta in bone remodeling. Clin Orthop. 1990;250:261-276. (Pubitemid 20033993)
53. Ellman MB, An HS, Muddasani P, et al. Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis. Gene. 2008;420:82-89.
54. Herbst RS. Review of epidermal growth factor receptor biology. Int J Radiat Oncol Bio Phys. 2004;59(suppl 2):21-26. (Pubitemid 38610223)
55. Yang D, Cheng J, Jing Z, et al. Platelet-derived growth factor (PDGF)-AA: a self imposed cytokine in the proliferation of human fetal osteoblasts. Cytokine. 2000;12:1271-1274. (Pubitemid 30611810)
56. Matsuda N, Lin WL, Kuman NM, et al. Mitogenic, chemotactic, and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro. J Periodontal. 1993;63:515-525.
57. Ferrara N, Gerber HP. The role of vascular endothelial growth factor in angiogenesis. Acta Haematol. 2001;106:148-156. (Pubitemid 34124153)
58. Qureshi AH, Chaoji V, Maiguel D, et al. Proteomic and phosphoproteomic profile of human platelets in basal, resting state: insight into integrin signaling. PLoS One. 2009;4:e7627.
59. Smyth SS, McEver RP, Weyrich AS, et al. 2009 Platelet Colloquium Participants. Platelet functions beyond hemostasis. J Thromb Haemost. 2009;7:1759-1766.
60. Elias I, Zoga AC, Morrison WB, et al. Osteochondral lesions of the talus: localization and morphologic data from 424 patients using a novel anatomical grid scheme. Foot Ankle Int. 2007;28:154-161. (Pubitemid 46185001)
61. Fansa AM, Murawski CD, Imhauser CW, et al. Autologous osteochondral transplantation of the talus partially restores contact mechanics of the ankle joint. Am J Sports Med. 2011;39:2457-2465.
62. Radin EL, Rose RM. Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop Relat Res. 1986; 213:34-40. (Pubitemid 17187796)
63. Sabokbar A, Crawford R, Murray DW, et al. Macrophage-osteoclast differentiation and bone resorption in osteoarthritic subchondral acetabular cysts. Acta Orthop Scand. 2000;71:255-261. (Pubitemid 30648929)
64. Von Rechenberg B, Leutenegger C, Zlinsky K, et al. Upregulation of mRNA of interleukin-1 and -6 in subchondral cystic lesions of four horses. Equine Vet J. 2001;33:143-149. (Pubitemid 33673440)
65. Alsousou J, Thompson M, Hulley P, et al. The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery: a review of the literature. J Bone Joint Surg Br. 2009;91:987-996.
66. Foster TE, Puskas BL, Mandelbaum BR, et al. Platelet-rich plasma: from basic science to clinical applications. Am J Sports Med. 2009;37:2259-2272.
67. Kon E, Buda R, Filardo G, et al. Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesions. Knee Surg Sports Traumatol Arthrosc. 2010;18: 472-479.
68. Spreafico A, Chellini F, Frediani B, et al. Biochemical investigation of the effects of human platelet releasates on human articular chondrocytes. J Cell Biochem. 2009;108:1153-1165.