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Volumn 73, Issue 3, 2011, Pages 255-261

Boswellia serrata, a potential antiinflammatory agent: An overview

Author keywords

Agent; antiinflammatory; Boswellia serrata; frankincense; olibanum; potential; Salai Salai guggul

Indexed keywords

11 KETO BETA BOSWELLIC ACID; ACETYL 11 OXO BETA BOSWELLIC ACID; ACETYL BETA BOSWELLIC ACID; ARACHIDONATE 5 LIPOXYGENASE; BETA BOSWELLIC ACID; BOSWELLIA SERRATA EXTRACT; BOSWELLIC ACID; DITERPENE; ESSENTIAL OIL; RESIN; TERPENE DERIVATIVE; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 84858122505     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.93507     Document Type: Review
Times cited : (292)

References (64)
  • 1
    • 0003831162 scopus 로고
    • Anon(CSIR) New Delhi: Council of Scientific and Industrial Research;
    • Anon (CSIR). The Wealth of India, Raw Materials, Vol. 1, New Delhi: Council of Scientific and Industrial Research; 1948.
    • (1948) The Wealth of India, Raw Materials , vol.1
  • 3
    • 84951506249 scopus 로고
    • Age-old resins of the mediterranean region and their uses
    • Howes FN. Age-old resins of the Mediterranean region and their uses. Econ Bot 1950;4:307-16.
    • (1950) Econ Bot , vol.4 , pp. 307-316
    • Howes, F.N.1
  • 4
    • 33750498125 scopus 로고
    • Salai guggul (from boswellia serrata Roxb.): Its exploitation and utilization
    • Krishnamurthy T, Shiva MP. Salai guggul (from Boswellia serrata Roxb.): Its exploitation and utilization. Indian Forest 1977;103:466-74.
    • (1977) Indian Forest , vol.103 , pp. 466-474
    • Krishnamurthy, T.1    Shiva, M.P.2
  • 6
    • 85068246337 scopus 로고    scopus 로고
    • Frankincense oil
    • Holmes P. Frankincense oil. Int J Arom 1999;9:56-61.
    • (1999) Int J Arom , vol.9 , pp. 56-61
    • Holmes, P.1
  • 7
    • 0002949538 scopus 로고
    • New constituents in olibanum resinoid and essential oils
    • Maupetit P. New constituents in olibanum resinoid and essential oils. Perfumer Flavorist 1984;9:19-37.
    • (1984) Perfumer Flavorist , vol.9 , pp. 19-37
    • Maupetit, P.1
  • 9
    • 0004183440 scopus 로고
    • 5th ed. London: J and A Churchill Limited;
    • Wallis TE. Textbook of Pharmacognosy. 5th ed. London: J and A Churchill Limited; 1967. p. 500-1.
    • (1967) Textbook of Pharmacognosy , pp. 500-501
    • Wallis, T.E.1
  • 10
  • 11
    • 2242475198 scopus 로고
    • Differentiation between resins from boswellia carterii and boswellia frereana (Frankincense) of somali region
    • Chiavari G, Galletti GC, Piccaglia R, Mohamud MA. Differentiation between resins from Boswellia carterii and Boswellia frereana (Frankincense) of Somali region. J Essential Oil Res 1991;3:185-6.
    • (1991) J Essential Oil Res , vol.3 , pp. 185-186
    • Chiavari, G.1    Galletti, G.C.2    Piccaglia, R.3    Mohamud, M.A.4
  • 12
    • 84858117271 scopus 로고
    • Studies on gum obtained from boswellia serrata roxb
    • Sharma RA, Verma KC. Studies on gum obtained from Boswellia serrata Roxb. Indian Drugs 1980;17:225.
    • (1980) Indian Drugs , vol.17 , pp. 225
    • Sharma, R.A.1    Verma, K.C.2
  • 13
    • 84858115878 scopus 로고
    • Constituents of gum obtained from boswellia serrata exudates
    • Bhuchar VM, Agarwal AK, Sharma SK. Constituents of gum obtained from Boswellia serrata exudates. Indian J Technol 1982;20:38.
    • (1982) Indian J Technol , vol.20 , pp. 38
    • Bhuchar, V.M.1    Agarwal, A.K.2    Sharma, S.K.3
  • 14
    • 21844512075 scopus 로고
    • Carbohydrate contents of boswellia serrata
    • Gangwal ML, Vardhan DK. Carbohydrate contents of Boswellia serrata. Asian J Chem 1995;7:677.
    • (1995) Asian J Chem , vol.7 , pp. 677
    • Gangwal, M.L.1    Vardhan, D.K.2
  • 15
    • 1542348606 scopus 로고    scopus 로고
    • Pharmacokinetic study of 11-keto-beta-boswellic acid
    • Sharma S, Thawani V, Hingorani L. Pharmacokinetic study of 11-keto-beta-boswellic acid. Phytomedicine 2004;11:255-60.
    • (2004) Phytomedicine , vol.11 , pp. 255-260
    • Sharma, S.1    Thawani, V.2    Hingorani, L.3
  • 16
    • 0032134839 scopus 로고    scopus 로고
    • Monograph boswellia serrata
    • Monograph Boswellia serrata. Altern Med Rev 1998;3:306-7.
    • (1998) Altern Med Rev , vol.3 , pp. 306-307
  • 17
    • 0000225819 scopus 로고
    • The antiinflammatory action of indian medicinal plants
    • Kirtikar KR, Basu BD. The antiinflammatory action of Indian medicinal plants. Indian Med Plants 1935;1:521-9.
    • (1935) Indian Med Plants , vol.1 , pp. 521-529
    • Kirtikar, K.R.1    Basu, B.D.2
  • 18
    • 0000557085 scopus 로고
    • Antiinflammatory agents from indian medicinal plants
    • Chatterjee GK, Pal SD. Antiinflammatory agents from Indian medicinal plants. Indian Drugs 1984;21:431.
    • (1984) Indian Drugs , vol.21 , pp. 431
    • Chatterjee, G.K.1    Pal, S.D.2
  • 20
    • 84858123801 scopus 로고    scopus 로고
    • Pharmacopoeia of India Govt. of India New Delhi: Ministry of Health and Family Welfare;
    • Pharmacopoeia of India, Govt. of India, New Delhi: Ministry of Health and Family Welfare; 2007. p. 2045.
    • (2007) , pp. 2045
  • 21
    • 36849000674 scopus 로고    scopus 로고
    • Delhi: Daya Publishing House;
    • Dhiman AK. Ayurvedic Drug Plants. Delhi: Daya Publishing House; 2006. p. 326-7.
    • (2006) Ayurvedic Drug Plants , pp. 326-327
    • Dhiman, A.K.1
  • 22
    • 0036765655 scopus 로고    scopus 로고
    • Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro
    • Hostanska K, Daum G, Saller R. Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro. Anticancer Res 2002;22:2853-62. (Pubitemid 36069325)
    • (2002) Anticancer Research , vol.22 , Issue.5 , pp. 2853-2862
    • Hostanska, K.1    Daum, G.2    Saller, R.3
  • 23
    • 33645113833 scopus 로고    scopus 로고
    • Frankincense and myrrh resources of ethiopia: Ii. Medicinal and industrial uses
    • Lemenih M, Teketay D. Frankincense and myrrh resources of Ethiopia: II. Medicinal and industrial uses. Ethiop J Sci 2003;26:161-72.
    • (2003) Ethiop J Sci , vol.26 , pp. 161-172
    • Lemenih, M.1    Teketay, D.2
  • 24
    • 0344256474 scopus 로고    scopus 로고
    • Characterization of archaeological frankincense by gas chromatography-mass spectrometry
    • DOI 10.1016/j.chroma.2003.10.016
    • Mathe C, Culioli G, Archier P. Characterization of archeological frankincense by gas chromatography mass spectrometry. J Chromatogr 2004;1023:277-85. (Pubitemid 37494801)
    • (2004) Journal of Chromatography A , vol.1023 , Issue.2 , pp. 277-285
    • Mathe, C.1    Culioli, G.2    Archier, P.3    Vieillescazes, C.4
  • 26
    • 0000211538 scopus 로고
    • Tetracyclic triterpene acids from the resin of boswellia serrata roxb
    • Pardhy RS, Bhattacharyya SC. Tetracyclic triterpene acids from the resin of Boswellia serrata Roxb. Indian J Chem 1978;16B:174-5.
    • (1978) Indian J Chem , vol.16 B , pp. 174-175
    • Pardhy, R.S.1    Bhattacharyya, S.C.2
  • 27
    • 0000211539 scopus 로고
    • Β-boswellic acid, acetyl-β-boswellic acid, acetyl-11-keto- β-boswellic acid and 11-keto-β-boswellic acid, four pentacyclic triterpenic acids from the resin of boswellia serrata roxb
    • Pardhy RS, Bhattacharyya SC. β-Boswellic acid, acetyl-β- boswellic acid, acetyl-11-keto-β-boswellic acid and 11-keto-β- boswellic acid, four pentacyclic triterpenic acids from the resin of Boswellia serrata Roxb. Indian J Chem 1978;16B:176-8.
    • (1978) Indian J Chem , vol.16 B , pp. 176-178
    • Pardhy, R.S.1    Bhattacharyya, S.C.2
  • 29
    • 84858132111 scopus 로고
    • Herbal raw material and traditional remedies
    • Handa SS. Herbal raw material and traditional remedies. Eastern Pharmacist 1995;3:24.
    • (1995) Eastern Pharmacist , vol.3 , pp. 24
    • Handa, S.S.1
  • 31
    • 0036280641 scopus 로고    scopus 로고
    • Standardization, quality control and GMP's for herbal drugs
    • Sane RT. Standardization, quality control, and GMP for herbal drug. Indian Drugs 2002;39:184-90. (Pubitemid 34692666)
    • (2002) Indian Drugs , vol.39 , Issue.3 , pp. 184-190
    • Sane, R.T.1
  • 33
    • 0025922660 scopus 로고
    • Inhibition of leukotriene B4 formation in rat peritoneal neutrophils by an ethanolic extract of gum-resin exudates of boswellia serrata
    • Ammon HP, Mack T, Singh GB, Safayhi H. Inhibition of leukotriene B4 formation in rat peritoneal neutrophils by an ethanolic extract of gum-resin exudates of Boswellia serrata. Planta Med 1991;57:203-7.
    • (1991) Planta Med , vol.57 , pp. 203-207
    • Ammon, H.P.1    MacK, T.2    Singh, G.B.3    Safayhi, H.4
  • 34
    • 0031751961 scopus 로고    scopus 로고
    • Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis
    • Wildfeuer A, Neu IS, Safayhi H, Metzger G, Wehrmann M, Vogel U, et al. Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis. Arzneim Forsch 1998;48:668-74. (Pubitemid 28308193)
    • (1998) Arzneimittel-Forschung/Drug Research , vol.48 , Issue.6 , pp. 668-674
    • Wildfeuer, A.1    Neu, I.S.2    Safayhi, H.3    Metzger, G.4    Wehrmann, M.5    Vogel, U.6    Ammon, H.P.T.7
  • 35
    • 0036360009 scopus 로고    scopus 로고
    • Boswellic acids (components of frankincense) as the active principle in treatment of chronic inflammatory diseases
    • Ammon HP. Boswellic acids (components of frankincense) as the active principle in treatment of chronic inflammatory diseases. Wien Med Wochenschr 2002;152:337-78.
    • (2002) Wien Med Wochenschr , vol.152 , pp. 337-378
    • Ammon, H.P.1
  • 36
    • 33750391774 scopus 로고    scopus 로고
    • Boswellic acids in chronic inflammatory diseases
    • DOI 10.1055/s-2006-947227
    • Ammon HP. Boswellic acids in chronic inflammatory diseases. Planta Med 2006;72:1100-16. (Pubitemid 44638909)
    • (2006) Planta Medica , vol.72 , Issue.12 , pp. 1100-1116
    • Ammon, H.P.T.1
  • 38
    • 0002541438 scopus 로고    scopus 로고
    • Special extract of BOSWELLIA serrata (H15) in the treatment of rheumatoid arthritis
    • Etzel R. Special extract of boswellia serrata (H15) in the treatment of rheumatoid arthritis. Phytomedicine 1996;3:91-4. (Pubitemid 126491960)
    • (1996) Phytomedicine , vol.3 , Issue.1 , pp. 91-94
    • Etzel, R.1
  • 39
    • 0007816143 scopus 로고    scopus 로고
    • Salai guggul-boswellia serrata from a herbal medicine to a specific inhibitor of leukotriene biosynthesis
    • Ammon HP. Salai guggul-Boswellia serrata from a herbal medicine to a specific inhibitor of leukotriene biosynthesis. Phytomedicine 1996;3:67-70.
    • (1996) Phytomedicine , vol.3 , pp. 67-70
    • Ammon, H.P.1
  • 40
    • 0014502765 scopus 로고
    • Studies on mechanism of action of salicylates v: Effect of salicylic acid on enzymes involved in mucopolysaccharide synthesis
    • Lee KH, Spencer MR. Studies on mechanism of action of salicylates V: Effect of salicylic acid on enzymes involved in mucopolysaccharide synthesis. J Pharmacol Sci 1969;58:464-8.
    • (1969) J Pharmacol Sci , vol.58 , pp. 464-468
    • Lee, K.H.1    Spencer, M.R.2
  • 41
    • 0018568715 scopus 로고
    • Effect of salicylate on proteoglycan metabolism in normal canine articular cartilage in vitro
    • Palmowski MJ, Brandt KD. Effect of salicylate on proteoglycan metabolism in normal canine articular cartilage in vitro. Arthritis Rheum 1979;22:746-54. (Pubitemid 10142183)
    • (1979) Arthritis and Rheumatism , vol.22 , Issue.7 , pp. 746-754
    • Palmoski, M.J.1    Brandt, K.D.2
  • 42
    • 0018993905 scopus 로고
    • The effect of anti-inflammatory drugs on glycosaminoglycan sulphation in pig cartilage
    • Dekel S, Falconer J, Francis MJ. The effect of anti-inflammatory drugs on glycosaminoglycan sulphation in pig cartilage. Prostaglandins Med 1980;4:133-40.
    • (1980) Prostaglandins Med , vol.4 , pp. 133-140
    • Dekel, S.1    Falconer, J.2    Francis, M.J.3
  • 43
    • 0021202444 scopus 로고
    • Effects of salicylates and other nonsteroidal anti-inflammatory drugs on articular cartilage
    • Brandt KD, Palmowski MJ. Effect of salicylates and other non-steroidal anti-inflammatory drugs on articular cartilage. Am J Med 1984;77:65-9. (Pubitemid 14050200)
    • (1984) American Journal of Medicine , vol.77 , Issue.A , pp. 65-69
    • Brandt, K.D.1    Palmoski, M.J.2
  • 44
    • 0024432046 scopus 로고
    • Studies on the metabolism of glycosaminoglycans under the influence of new herbal anti-inflammatory agents
    • DOI 10.1016/0006-2952(89)90124-X
    • Reddy GK, Chandraksan G, Dhar SC. Studies on the metabolism of glycosaminoglycans under the influence of new herbal ant-inflammatory agents. Biochem Pharm 1989;38:3527-34. (Pubitemid 19250206)
    • (1989) Biochemical Pharmacology , vol.38 , Issue.20 , pp. 3527-3534
    • Kesava Reddy, G.1    Chandrakasan, G.2    Dhar, S.C.3
  • 45
    • 28944445468 scopus 로고
    • Mechanism of antiinflammatory actions of curcumine and boswellic acids
    • Ammon HP, Safayhi H, Mack T, Sabieraj J. Mechanism of anti-inflammatory actions of curcumine and boswellic acids. J Ethnopharmacol 1993;38:113-9. (Pubitemid 23136055)
    • (1993) Journal of Ethnopharmacology , vol.38 , Issue.2-3 , pp. 113-119
    • Ammon, H.P.T.1    Safayhi, N.2    Mack, T.3    Sabieraj, J.4
  • 46
    • 0029035973 scopus 로고
    • Mechanism of 5-Lipoxygenase inhibition by acetyl-11-keto-boswellic acid
    • Safayhi H, Sailer ER, Ammon HP. Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-boswellic acid. Mol Pharmacol 1995;47:1212-6.
    • (1995) Mol Pharmacol , vol.47 , pp. 1212-1216
    • Safayhi, H.1    Sailer, E.R.2    Ammon, H.P.3
  • 47
    • 0007856985 scopus 로고    scopus 로고
    • Boswellic acids and protease activities
    • Rall B, Ammon HP, Safayhi H. Boswellic acids and protease activities. Phytomed 1996;3:75-6. (Pubitemid 126491956)
    • (1996) Phytomedicine , vol.3 , Issue.1 , pp. 75-76
    • Rall, B.1    Ammon, H.P.T.2    Safayhi, H.3
  • 49
    • 77950065451 scopus 로고
    • Pharmacology of an extract of salai guggul ex-boswellia serrata
    • Singh GB, Atal CK. Pharmacology of an extract of salai guggul ex-Boswellia serrata. Indian J Pharmacol 1984;16:51.
    • (1984) Indian J Pharmacol , vol.16 , pp. 51
    • Singh, G.B.1    Atal, C.K.2
  • 50
    • 0025766095 scopus 로고
    • Treatment of osteoarthritis with A herbomineral formulation: A double blind, placebo-controlled, cross-over study
    • Kulkarni R, Patki P, Jog V, Gandage S, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: A double blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5.
    • (1991) J Ethnopharmacol , vol.33 , pp. 91-95
    • Kulkarni, R.1    Patki, P.2    Jog, V.3    Gandage, S.4    Patwardhan, B.5
  • 51
    • 0034040862 scopus 로고    scopus 로고
    • Randomized double blind trial of an Ayurvedic plant derived formulation for treatment of rheumatoid arthritis
    • Chopra A, Lavin P, Patwardhan B, Chitre D. Randomized double blind trial of an Ayurvedic plant derived formulation for treatment of rheumatoid arthritis. J Rheumatol 2000;27:1365-72. (Pubitemid 30354029)
    • (2000) Journal of Rheumatology , vol.27 , Issue.6 , pp. 1365-1372
    • Chopra, A.1    Lavin, P.2    Patwardhan, B.3    Chitre, D.4
  • 53
    • 0015102987 scopus 로고
    • Anti-inflammatory studies on curcuma longa (turmeric)
    • Arora RB, Kapoor V, Basu N, Jain AP. Anti-inflammatory studies on Curcuma longa (turmeric). Indian J Med Res 1971;50:1289-95.
    • (1971) Indian J Med Res , vol.50 , pp. 1289-1295
    • Arora, R.B.1    Kapoor, V.2    Basu, N.3    Jain, A.P.4
  • 54
    • 0026788146 scopus 로고
    • A sensitive and relevant model for evaluating antiinflammatory activity-Papaya latex-Induced rat paw edema
    • Gupta OP, Sharma N, Chand D. A sensitive and relevant model for evaluating antiinflammatory activity-papaya latex-induced rat paw edema. J Pharmacol Toxicol Methods 1992;28:15-9.
    • (1992) J Pharmacol Toxicol Methods , vol.28 , pp. 15-19
    • Gupta, O.P.1    Sharma, N.2    Chand, D.3
  • 55
    • 33845321884 scopus 로고    scopus 로고
    • Boswellic acids: Biological actions and molecular targets
    • DOI 10.2174/092986706779010333
    • Poeckel D, Werz O. Boswellic acids: Biological actions and molecular targets. Curr Med Chem 2006;13:3359-69. (Pubitemid 44873750)
    • (2006) Current Medicinal Chemistry , vol.13 , Issue.28 , pp. 3359-3369
    • Poeckel, D.1    Werz, O.2
  • 56
    • 0024462668 scopus 로고
    • Anti-arthritic activity of boswellic acids in bovine serum albumin (BSA)-induced arthritis
    • Sharma ML, Bani S, Singh GB. Anti-arthritic activity of boswellic acids in bovine serum albumin (BSA)-induced arthritis. Int Immunopharmacol 1989;11:647-52. (Pubitemid 19239439)
    • (1989) International Journal of Immunopharmacology , vol.11 , Issue.6 , pp. 647-652
    • Sharma, M.L.1    Bani, S.2    Singh, G.B.3
  • 57
    • 33847047219 scopus 로고    scopus 로고
    • Pure compound from Boswellia serrata extract exhibits anti-inflammatory property in human PBMCs and mouse macrophages through inhibition of TNFα, IL-1β, NO and MAP kinases
    • DOI 10.1016/j.intimp.2006.12.003, PII S1567576906003791
    • Gayathri B, Manjula N, Vinaykumar KS, Lakshmi BS, Balakrishnan A. Pure compound from Boswellia serrata extract exhibits antiinflammatory property in human PBMCs and mouse macrophages through inhibition of TNF alpha, IL-1beta, NO and MAP kinases. Int Immunopharmacol 2007;7:473-82. (Pubitemid 46275555)
    • (2007) International Immunopharmacology , vol.7 , Issue.4 , pp. 473-482
    • Gayathri, B.1    Manjula, N.2    Vinaykumar, K.S.3    Lakshmi, B.S.4    Balakrishnan, A.5
  • 59
    • 61449166861 scopus 로고    scopus 로고
    • On the interference of boswellic acids with 5-Lipoxygenase: Mechanistic studies in vitro and pharmacological relevance
    • Siemoneit U, Pergola C, Jazzar B, Northoff H, Skarke C, Jauch J, et al. On the interference of boswellic acids with 5-lipoxygenase: Mechanistic studies in vitro and pharmacological relevance. Eur J Pharmacol 2009;606:246-54.
    • (2009) Eur J Pharmacol , vol.606 , pp. 246-254
    • Siemoneit, U.1    Pergola, C.2    Jazzar, B.3    Northoff, H.4    Skarke, C.5    Jauch, J.6
  • 60
    • 67651005688 scopus 로고    scopus 로고
    • Acetyl-11-keto-β-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-Mediated angiogenesis
    • Pang X, Yi Z, Zhang X, Sung B, Qu W, Lian X, et al. Acetyl-11-keto- β-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis. Cancer Res 2009;69:5893-900.
    • (2009) Cancer Res , vol.69 , pp. 5893-5900
    • Pang, X.1    Yi, Z.2    Zhang, X.3    Sung, B.4    Qu, W.5    Lian, X.6
  • 61
    • 84858135493 scopus 로고    scopus 로고
    • Anonymous 4 August Available from Last accessed on 2011 May 18
    • Anonymous. Indian herb hope for arthritis relief. The Telegraph Calcutta, 4 August, 2008. p. 7. Available from: http://www.telegraphindia.com/1080804/ jsp/nation/story-9643877.jsp#top, Last accessed on 2011 May 18.
    • (2008) Indian Herb Hope for Arthritis Relief. The Telegraph Calcutta , pp. 7
  • 62
    • 79959850901 scopus 로고    scopus 로고
    • Physico-chemical standardization and development of HPTLC method for the determination of β-boswellic acid from boswellia serrata roxb. (exudate)
    • Pawar RK, Sharma S, Singh KC, Sharma RK. Physico-chemical standardization and development of HPTLC method for the determination of β-boswellic acid from Boswellia serrata Roxb. (exudate). Int J App Pharm 2011;3:8-13.
    • (2011) Int J App Pharm , vol.3 , pp. 8-13
    • Pawar, R.K.1    Sharma, S.2    Singh, K.C.3    Sharma, R.K.4
  • 64
    • 0038183455 scopus 로고    scopus 로고
    • Dabur Research Foundation and Dabur Ayurved Limited New York: Churchill Livingston;
    • Dabur Research Foundation and Dabur Ayurved Limited. Major herbs of Ayurveda. New York: Churchill Livingston; 2002.
    • (2002) Major Herbs of Ayurveda


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