The effect of ghrelin pretreatment on epididymal sperm quality and tissue antioxidant enzyme activities after testicular ischemia/reperfusion in rats

Journal of Physiology and Biochemistry

Volumn 68, Issue 1, 2012, Pages 91-97

  Taati, Majid ^a   Moghadasi, Mehrnoush ^b   Dezfoulian, Omid ^a   Asadian, Payman ^a   Kheradmand, Arash ^a   Abbasi, Mohsen ^a   Zendehdel, Morteza ^c  

^a LORESTAN UNIVERSITY   (Iran)

^b LORESTAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c UNIVERSITY OF TEHRAN   (Iran)

Author keywords

Antioxidant enzymes; Ghrelin; Ischemia reperfusion; Testes

Indexed keywords

ANTIOXIDANT; CATALASE; GHRELIN; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EPIDIDYMIS; ISCHEMIA; LIPID PEROXIDATION; MALE; MALE GENITAL TRACT PARAMETERS; NONHUMAN; ORCHIECTOMY; RAT; REPERFUSION; SPERMATOZOON DENSITY; SPERMATOZOON MOTILITY; TESTIS INJURY; TESTIS ISCHEMIA;

ANIMALS; ANTIOXIDANTS; CATALASE; CELL MEMBRANE; EPIDIDYMIS; GHRELIN; GLUTATHIONE PEROXIDASE; ISCHEMIA; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; RATS; RATS, WISTAR; REPERFUSION INJURY; SPERM MOTILITY; SPERMATOZOA; SUPEROXIDE DISMUTASE; TESTIS;

RATTUS; RATTUS NORVEGICUS;

EID: 84858076376     PISSN: 11387548     EISSN: 18778755     Source Type: Journal    
DOI: 10.1007/s13105-011-0122-2     Document Type: Article

References (32)

1. Abasiyanik A, Daǧdönderen L (2004) Beneficial effects of melatonin compared with allopurinol in experimental testicular torsion. J Pediatr Surg 39:1238-4121
2. Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121-126
3. Akgur FM, Kilinc K, Aktug T (1993) Reperfusion injury after detorsion of unilateral testicular torsion. Urol Res 21:395-399 (Pubitemid 24053897)
4. Aurich JE, Schonherr U, Hoppe H, Aurich C (1997) Effects of antioxidants on motility and membrane integrity of chilled stored stallion semen. Theriogenology 48:185-192 (Pubitemid 28137127)
5. Beheshtian A, Salmasi AH, Payabvash S, Kiumehr S, Ghazinezami B, Rahimpour S, Tavangar SM, Dehpour AR (2008) Protective effects of sildenafil administration on testicular torsion/detorsion damage in rats. World J Urol 26:197-202
6. Buege JA, Aust SD (1978) Microsomal lipid peroxidation. Methods Enzymol 52:302-310
7. Cancel AM, Lobdell D, Mendola P, Perreault SD (2000) Objective evaluation of hyperactivated motility in rat spermatozoa using computer-assisted sperm analysis. Hum Reprod 15:1322-1328 (Pubitemid 30335958)
8. Cuzzocrea S, Riley DP, Caputi AP, Salvemini D (2001) Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharmacol Rev 53:135-159 (Pubitemid 32173112)
9. Garcia YJ, Rodriguez-Malaver AJ, Penaloza N (2005) Lipid peroxidation measurement by thiobarbituric acid assay in rat cerebellar slices. J Neurosci Meth 144:127-135 (Pubitemid 40546309)
10. 2 at physiological concentrations modulates leydig cell function inducing oxidative stress and apoptosis. Apoptosis 11:39-46
11. Hsieh Y, Guan Y, Tu C, Bratt PJ, Angerhofer JR, Lepock M, Hickey MJ, Tainer JA, Nick HS, Silverman DN (1998) Probing the active site of human manganese superoxide dismutase: the role of glutamine. Biochemistry 37:4731-4739 (Pubitemid 28175952)
12. Kheradmand A, Alirezaei M, Asadian P, Rafiei Alavi E, Joorabi S (2009) Antioxidant enzyme activity and MDA level in the rat testis following chronic administration of ghrelin. Andrologia 41:1-6
13. Kheradmand A, Taati M, Babaei H (2009) The effects of chronic administration of ghrelin on rat sperm quality and membrane integrity. Anim Biol 59:159-168
14. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K (1999) Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402:656-660 (Pubitemid 129516334)
15. Konturek PC, Brzozowski T, Walter B, Burnat G, Hess T, Hahn EG, Konturek SJ (2006) Ghrelin-induced gastroprotection against ischemia-reperfusion injury involves an activation of sensory afferent nerves and hyperemia mediated by nitric oxide. Eur J Pharmacol 536:171-181
16. Korbonits M, Goldstone AP, Gueorguiev M, Grossman AB (2004) Ghrelin: a hormone with multiple functions. Front Neuroendocrinol 25:27-68
17. Kurcer Z, Hekimoglu A, Aral F, Baba F, Sahna E (2010) Effect of melatonin on epididymal sperm quality after testicular ischemia/reperfusion in rats. Fertil Steril 93:1545-1549
18. Lin C, Yongsheng R, Xiuhua L, Wei Gen L, Jinghui Y, Bin G, Neal LW, Chaoshu T (2004) Protective effects of ghrelin on ischemia/reperfusion injury in the isolated rat heart. J Cardiovasc Pharm 43:165-170
19. Lowry O, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurements with the folin phenol reagent. J Biol Chem 193:265-275
20. Payabvash S, Kiumehr S, Tavangar SM, Dehpour AR (2008) Ethyl pyruvate reduces germ cell-specific apoptosis and oxidative stress in rat model of testicular torsion/ detorsion. J Pediatr Surg 43:705-712 (Pubitemid 351474556)
21. Peltola V, Huhtaniemi I, Ahotupa M (1992) Antioxidant enzyme activity in the maturing rat testis. J Androl 13:450-455
22. Pons E, Sipila P, Britan A, Vernet P, Poutaneri M, Huhtaniemi I, Drevet JR (2003) Epididymal expression of mouse GPX proteins: analysis of the mechanisms of GPX5 tissue and region-specific expression through in vitro and in vivo approaches. In: Hinton BT, Turner TT (eds) Third International Conference on the Epididymis. The Van Doren Company, Charlottesville, pp 74-93
23. Qian ZJ, Jung WK, Kim SK (2008) Free radical scavenging activity of a novel antioxidant peptide purified from hydrolysate of bullfrog skin, Rana catesbeiana shaw. Bioresource Technol 99:1690-1698
24. Sliwa L, Macura B (2005) Evaluation of cell membrane integrity of spermatozoa by hypoosmotic swelling testwater test in mice after intraperitoneal daidzein administration. Archives Androl 51:443-44825.
25. Somuncu S, Cakmak M, Erdogan S, Caglayan O, Akman H, Kaya M (2006) Protective effects of trapidil in ischemia-reperfusion injury due to testicular torsion and detorsion: an experimental study. Int J Urol 13:601-605
26. Sonmez M, Turk G, Yuce A (2005) The effect of ascorbic acid supplementation on sperm quality, lipid peroxidation and testosterone levels of male Wistar rats. Theriogenology 63:2063-2072 (Pubitemid 40483159)
27. Turner TT, Lysiak JJ (2008) Oxidative stress: a common factor in testicular dysfunction. J Androl 29:488-498
28. Turner TT, Bang HJ, Lysiak JL (2004) The molecular pathology of experimental testicular torsion suggests adjunct therapy to surgical repair. J Urol 172:2574-2578 (Pubitemid 39507473)
29. Turner TT, Tung KS, Tomomasa H, Wilson LW (1997) Acute testicular ischemia results in germ cell-specific apoptosis in the rat. Biol Reprod 57:1267-1274 (Pubitemid 27516628)
30. Ustün H, Akgül KT, Ayyildiz A et al (2008) Effect of phosphodiesterase 5 inhibitors on apoptosis and nitric oxide synthases in testis torsion: an experimental study. Pediatr Surg Int 24:205-211
31. Visser AJ, Heyns JF (2003) Testicular function after torsion of the spermatic cord. BJU Int 92:200-203 (Pubitemid 36966577)
32. Yurtcu M, Abasiyanik A, Avunduk MC, Muhtaroglu S (2008) Effects of melatonin on spermatogenesis and testicular ischemia reperfusion injury after unilateral testicular torsion-detorsion. J Pediatr Surg 43:1873-1878