Antioxidant enzyme activity and MDA level in the rat testis following chronic administration of ghrelin

Andrologia

Volumn 41, Issue 6, 2009, Pages 335-340

  Kheradmand, A ^a,b   Alirezaei, M ^a   Asadian, P ^a   Rafiei Alavi, E ^b   Joorabi, S ^c  

^a LORESTAN UNIVERSITY   (Iran)

^b LORESTAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c Lorestan University of Medical Sciences ^*  (Iran)

Author keywords

Antioxidant enzymes; Ghrelin; MDA; Rat

Indexed keywords

CATALASE; GHRELIN; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVITY; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; TESTIS;

ANIMALS; CATALASE; DRUG ADMINISTRATION SCHEDULE; GHRELIN; GLUTATHIONE PEROXIDASE; INJECTIONS, SUBCUTANEOUS; MALE; MALONDIALDEHYDE; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; TESTIS; TIME FACTORS;

EID: 70449366433     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/j.1439-0272.2009.00932.x     Document Type: Article

References (37)

1. Aebi H (1984) Catalase in vitro. Methods Enzymol 105 : 121 126.
2. Aitken RJ, Clarkson JS, Fishel S (1989) Generation of reactive oxygen species, lipid peroxidation and human sperm function. Biol Reprod 41 : 183 197.
3. Barreiro ML, Tena-Sempere M (2004) Ghrelin and reproduction: a novel signal linking energy status and fertility? Mol Cell Endocrinol 226 : 1 9.
4. Bauche F, Fouchard MH, Jegou B (1994) Antioxidant system in rat testicular cells. FEBS Lett 349 : 392 396.
5. Buege JA, Aust SD (1978) Microsomal lipid peroxidation. Methods Enzymol 52 : 302 310.
6. Chapin RE, Phelps J (1990) Recent advances in testicular cell culture: implications for toxicology. Toxic In Vitro 4 : 543 559.
7. Cutler RG (1991) Human longevity and aging: possible role of reactive oxygen species. Ann N Y Acad Sci 621 : 1 28.
8. Dong MH, Kaunitz JD (2006) Gastroduodenal mucosal defense. Curr Opin Gastroentrol 22 : 599 606.
9. Fernandez-Fernandez R, Navarro VM, Barreiro ML, Vigo EM, Tovar S, Sirotkin AV, Casanueva FF, Aguilar E, Dieguez C, Pinilla L, Tene-Sempere M (2005) Effect of chronic hyperghrelinemia on puberty onset and pregnancy outcome in the rat. Endocrinology 146 : 3018 3025.
10. Garcia YJ, Rodriguez-Malaver AJ, Penaloza N (2005) Lipid peroxidation measurement by thiobarbituric acid assay in rat cerebellar slices. J Neurosci Meth 144 : 127 135.
11. Gomes WR (1970) Physiology of Reproduction. In : Johnson AD, Gomes WR, Vandemark NL (eds). The Testis. Vol. 3, Academic Press, New York, pp 483 545.
12. Hu Y, Rosen DJ, Zhou Y (2005) Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress. J Biol Chem 280 : 39485 39492.
13. Husain K, Scott BR, Reddy SK, Somani SM (2001) Chronic ethanol and nicotine interaction on rat tissue antioxidant defense system. Alcohol 25 : 89 97.
14. Ihrig TJ, Renston RH, Renston JP, Gondos B (1974) Catalase activity in the developing rabbit testis. J Reprod Fertil 39 : 105 108.
15. Iseri SO, Sener G, Yuksel M, Contuk G, Cetinel S, Gedik N, Yegen BC (2005) Ghrelin against alendronate-induced gastric damage in rats. J Endocrinol 187 : 399 406.
16. Kawczynska-Drozdz A, Olszanecki R, Jawein J, Brzozowski T, Pawlik WW, Korbut R, Guzik TJ (2006) Ghrelin inhibits vascular superoxide production in spontaneously hypertensive rats. Am J Hypertens 19 : 764 767.
17. Kojima M, Kanagawa K (2005) Ghrelin: structure and function. Physiol Rev 85 : 495 522.
18. Le Grande CE (1970) Radioprotectors and Anticarcinogens. In : Johnson AD, Gomes WR, Vandemark NL (eds). The Testis. Vol. 3, Academic Press, New York, pp 333 365.
19. Lowry O, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurements with the folin phenol reagent. J Biol Chem 193 : 265 275.
20. Mirault ME, Tremblay A, Beaudoin N, Tremblay M (1991) Overexpression of seleno-glutathione peroxidase by gene transfer enhances the resistance of T47D human breast cells to clastogenic oxidants. J Biol Chem 266 : 20752 20760.
21. Obay BD, Tasdemir E, Tumer C, Bilgin HM, Atmaca M (2008) Dose dependent effects of ghrelin on pentylenetetrazole-induced oxidative stress in a rat seizure model. Peptides 29 : 448 455.
22. Peltola V, Huhtaniemi I, Ahotupa M (1992) Antioxidant enzyme activity in the maturing rat testis. J Androl 13 : 450 455.
23. Petrie A, Watson P (1999) Statistics for Veterinary and Animal Science. Blackwell Science, London, pp 93 102.
24. Qian ZJ, Jung WK, Kim SK (2008) Free radical scavenging activity of a novel antioxidant peptide purified from hydrolysate of bullfrog skin, Rana catesbeiana shaw. Bioresource Technol 99 : 1690 1698.
25. Raes M, Michiels C, Remacle J (1987) Comparative study of the enzymatic defense systems against oxygen-derived free radicals: the key role of glutathione peroxidase. Free Radic Bio Med 3 : 3 7.
26. Robinson BS, Johnson DW, Poulos A (1992) Novel molecular species of sphingomyelin containing 2-hydroxylated polyenoic very-long-chain fatty acids in mammalian testes and spermatozoa. J Biol Chem 267 : 1746 1751.
27. 2-induced lipid peroxidation in rat brain homogenates is greatly reduced by melatonNeurosci Lett 195 : 203 205.
28. Sieja K, Talerczyk M (2004) Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy. Gynecol Oncol 93 : 320 327.
29. Tena-Sempere M, Barreiro ML, Gonzalez LC, Gaytan F, Zhang FP, Caminos JE, Pinilla L, Casanueva FF, Dieguez C, Aguilar E (2002) Novel expression and functional role of ghrelin in rat testis. Endocrinology 143 : 717 725.
30. Tian L, Cai Q, Wei H (1998) Alterations of antioxidant enzymes and oxidative damage to macromolecules in different organs of rats during aging. Free Radic Bio Med 24 : 1477 1484.
31. Tramer F, Rocco F, Micali F, Sandri G, Panfili E (1998) Antioxidant systems in rat epididymal spermatozoa. Biol Reprod 59 : 753 758.
32. Van Loon AAWM, Den Boer PJ, van der Schans GP, Mackenbach P, Grootegoed JA, Baan RA, Lohman PHM (1991) Immunochemical detection of DNA damage induction and repair at different cellular stages of spermatogenesis of the hamster after in vitro or in vivo exposure to ionizing radiation. Exp Cell Res 193 : 303 309.
33. Wren AM, Small CJ, Thomas EL, Abbott CR, Dhillo WS, Seal LJ, Cohen MA, Batterham RL, Taheri S, Stanley SA, Ghatei MA, Bloom SR (2001) Ghrelin causes hyperphagia and obesity in rats. Diabetes 50 : 2540 2547. (Pubitemid 33642772)
34. Yada T, Kaiya H, Mutoh K, Azuma T, Hyodo S, Kangawa K (2006) Ghrelin stimulates phagocytosis and superoxide production in fish leukocytes. J Endocrionol 189 : 57 65.
35. Yao P, Li K, Jin Y, Song F, Zhou S, Sun X (2006) Oxidative damage after chronic ethanol intake in rat tissues: prophylaxis of Ginkgo biloba extract. Food Chem 99 : 305 314.
36. Yao P, Li K, Song F, Zhou S, Sun X, Zhang X, Nussler AK, Liu L (2007) Heme oxygenase-1 upregulated by Ginkgo biloba extract: potential protection against ethanol-induced oxidative liver damage. Food Chem Toxicol 45 : 1333 1342.
37. Zwirska-Korczala K, Adamczyk-Sowa M, Sowa P, Pilc K, Suchanek R, Pierzchala K, Namyslowski G, Misiolek M, Sodowski K, Kato I, Kuwahara A, Zabielski R (2007) Role of leptin, ghrelin, angiotensin Π and orexins in 3T3 L1 preadipocyte cells proliferation and oxidative metabolism. J Physiol Pharmacol 58 : 53 64.