Comparison of reversed-phase/cation-exchange/anion-exchange trimodal stationary phases and their use in active pharmaceutical ingredient and counterion determinations

Journal of Chromatography A

Volumn 1232, Issue , 2012, Pages 190-195

  Liu, Xiaodong ^a   Pohl, Christopher A ^a  

^a Thermo Fisher Scientific   (United States)

Author keywords

Active pharmaceutical ingredient (API); Chromatography properties; Counterions; Mixed mode chromatography; Retention behavior; Trimodal stationary phases

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; COUNTERIONS; MIXED-MODE CHROMATOGRAPHY; RETENTION BEHAVIOR; STATIONARY PHASIS;

COLUMN CHROMATOGRAPHY; DRUG PRODUCTS; ORGANIC SOLVENTS; POLYVINYL ALCOHOLS; POSITIVE IONS;

ION EXCHANGE;

BUFFER; ORGANIC SOLVENT;

ANALYTICAL PARAMETERS; ANION EXCHANGE CAPACITY; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; CONTROLLED STUDY; HYDROPHILICITY; HYDROPHOBICITY; INTERMETHOD COMPARISON; ION EXCHANGE CAPACITY; ION EXCHANGE CHROMATOGRAPHY; PARTICLE SIZE; PH; PRIORITY JOURNAL; REVERSED PHASE CAPACITY; REVERSED PHASE LIQUID CHROMATOGRAPHY; STATIC ELECTRICITY;

ANIONS; BUFFERS; CATIONS; CHROMATOGRAPHY, ION EXCHANGE; CHROMATOGRAPHY, REVERSE-PHASE; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, CHEMICAL; PHARMACEUTICAL PREPARATIONS; SOLVENTS;

EID: 84858075211     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.12.009     Document Type: Article

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