Antitumor effect of Croton lechleri Mull. Arg. (Euphorbiaceae)

Journal of Ethnopharmacology

Volumn 140, Issue 2, 2012, Pages 438-442

  Alonso Castro, Angel Josabad ^a,b   Ortiz Sánchez, Elizabeth ^b   Domínguez, Fabiola ^c   López Toledo, Gabriela ^b   Chávez, Marco ^c   Ortiz Tello, Angel De Jesús ^b   García Carrancá, Alejandro ^a,b,d  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO NACIONAL DE CANCEROLOGÍA   (Mexico)

^c INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^d CMN Siglo XXI ^*  (Mexico)

Author keywords

Antitumor; Cancer; Croton lechleri; Cytotoxic; Toxicity

Indexed keywords

ANTINEOPLASTIC AGENT; CROTON LECHLERI EXTRACT; PLANT EXTRACT; RUTOSIDE; UNCLASSIFIED DRUG; VITEXIN;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL ASSAY; CONTROLLED STUDY; CROTON LECHLERI; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG EFFECT; EUPHORBIACEAE; FEMALE; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; IC 50; IN VIVO STUDY; LD 50; MEDICINAL PLANT; MOUSE; NONHUMAN; ORGAN WEIGHT; PLANT LEAF; TUMOR VOLUME; UTERINE CERVIX TUMOR;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE; CROTON; FEMALE; HELA CELLS; HUMANS; LETHAL DOSE 50; MICE; MICE, INBRED C57BL; PHYTOTHERAPY; PLANT EXTRACTS; UTERINE CERVICAL NEOPLASMS;

ALEXA; CROTON LECHLERI; EUPHORBIACEAE; MUS;

EID: 84858004727     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.01.009     Document Type: Article

References (11)

1. Alonso-Castro, A.J., Zapata-Bustos, R., Domínguez, F., García-Carrancá, A., Salazar-Olivo, L.A., 2011. Magnolia dealbata Zucc and its active principles honokiol and magnolol stimulate glucose uptake in murine and human adipocytes using the insulin-signaling pathway. Phytomedicine 18, 926-933.
2. Bezerra, D.P., Marinho Filho, J.D., Alves, A.P., Pessoa, C., de Moraes, M.O., Pessoa, O.D., Torres, M.C., Silveira, E.R., Viana, F.A., Costa-Lotufo, L.V., 2009. Antitumor activity of the essential oil from the leaves of Croton regelianus and its component ascaridole. Chemistry and Biodiversity 6, 1224-1231.
3. Capasso, A., Piacente, S., Cumanda, J., De Tomassi, N., Ragucci, M., Pizza, C., 1998. Flavonol glycosides from Croton menthodorus reduce in vitro morphine withdrawal. Pharmaceutical Biology 36, 310-314. (Pubitemid 29346559)
4. Chen, Z.P., Cai, Y., Phillipson, J.D., 1994. Studies on the anti-tumour, anti-bacterial, and wound-healing properties of Dragon's blood. Planta Medica 60, 541-545. (Pubitemid 24382564)
5. Krebs, H.C., Ramiarantsoa, H., 1997. Clerodane diterpenes of Croton hovarum. Phytochemistry 45, 379-381. (Pubitemid 27180910)
6. Lorke, D., 1983. A new approach to partial acute toxicity testing. Archives of Toxicology 54, 275-287. (Pubitemid 14205493)
7. Ortiz-Sánchez, E., Daniels, T.R., Helguera, G., Martinez-Maza, O., Bonavida, B., Penichet, M.L., 2009. Enhanced cytotoxicity of an anti-transferrin receptor IgG3-avidin fusion protein in combination with gambogic acid against human malignant hematopoietic cells: functional relevance of iron, the receptor, and reactive oxygen species. Leukemia 23, 59-70.
8. Rossi, D., Bruni, R., Bianchi, N., Chiarabelli, C., Gambari, R., Medici, A., Lista, A., Paganetto, G., 2003. Evaluation of the mutagenic, antimutagenic and antiproliferative potential of Croton lechleri (Muell Arg.) latex. Phytomedicine 10, 139-144. (Pubitemid 36433208)
9. Suffness, M., Pezzuto, J.M., 1990. Assays related to cancer drug discovery. In: Hostettmann, K. (Ed.), Methods in Plant Biochemistry: Assays for Bioactivity, vol. 6. Academic Press, London, pp. 71-133.
10. Ubillas, R., Jolad, S.D., Bruening, R.C., Kernan, M.R., King, S.R., King Sesin, D.F., Barrett, M., Stoddart, C.A., Flaster, T., Kuo, J., Ayals, F., Meza, E., Castanel, M., McMeekin, D., Rozhon, E., Tempesta, M.S., Barnard, D., Huffman, J., Smee, D., Sidwell, R., Soike, K., Brazier, A., Safrin, S., Orlando, R., Kenny, P.T.M., Berova, N., Nakanishi, K., 1994. SP-303, an antiviral oligomeric proanthocyanidin from the latex of Croton lechleri (Sangre de Drago). Phytomedicine 1, 77-106.
11. Zou, G.A., Su, Z.H., Zhang, H.W., Wang, Y., Yang, J.S., Zou, Z.M., 2010. Flavonoids from the stems of Croton caudatus Geisel var. tomentosus Hook. Molecules 15, 1097-1102.