Pinhole micro-SPECT/CT for noninvasive monitoring and quantitation of oncolytic virus dispersion and percent infection in solid tumors

Gene Therapy

Volumn 19, Issue 3, 2012, Pages 279-287

  Penheiter, A R ^a   Griesmann, G E ^a   Federspiel, M J ^a,b   Dingli, D ^a   Russell, S J ^a   Carlson, S K ^a  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

measles virus; micro SPECT CT; NIS; oncolytic virus; quantitation; sodium iodide symporter

Indexed keywords

IODINE 123; ONCOLYTIC VIRUS; RADIOISOTOPE; SODIUM IODIDE SYMPORTER; TECHNETIUM 99M; VIRUS RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DISPERSION; DRUG DISTRIBUTION; DRUG TUMOR LEVEL; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MEASLES VIRUS; NON INVASIVE PROCEDURE; NONHUMAN; ONCOLYTIC VIROTHERAPY; PANCREAS TUMOR; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOLID TUMOR; TUMOR CELL; TUMOR LOCALIZATION; TUMOR VOLUME; TUMOR XENOGRAFT; VIRUS LOAD;

ANIMALS; CELL LINE; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; IODINE RADIOISOTOPES; MICE; MICE, NUDE; NEOPLASMS; ONCOLYTIC VIRUSES; SENSITIVITY AND SPECIFICITY; SYMPORTERS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA; MEASLES VIRUS; MUS;

EID: 84858003007     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.107     Document Type: Article

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