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Volumn 419, Issue 2, 2012, Pages 299-304

Ghrelin modulates testicular germ cells apoptosis and proliferation in adult normal rats

Author keywords

Apoptosis; Bax; Ghrelin; PCNA; Rat; Spermatogenesis

Indexed keywords

CASPASE 3; CYCLINE; GHRELIN; PROTEIN BAX; PROTEIN BCL 2;

EID: 84857998195     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.02.014     Document Type: Article
Times cited : (29)

References (36)
  • 3
    • 0020806536 scopus 로고
    • Further quantification of human spermatogenesis: germ cell loss during postprophase of meiosis and its relationship to daily sperm production
    • Johnson L., Petty C.S., Neaves W.B. Further quantification of human spermatogenesis: germ cell loss during postprophase of meiosis and its relationship to daily sperm production. Biol. Reprod. 1983, 29:207-215.
    • (1983) Biol. Reprod. , vol.29 , pp. 207-215
    • Johnson, L.1    Petty, C.S.2    Neaves, W.B.3
  • 4
    • 5644248156 scopus 로고    scopus 로고
    • Ghrelin and reproduction: a novel signal linking energy status and fertility
    • Barreiro M.L., Tena-Sempere M. Ghrelin and reproduction: a novel signal linking energy status and fertility. Mol. Cell. Endocrinol. 2004, 226:1-9.
    • (2004) Mol. Cell. Endocrinol. , vol.226 , pp. 1-9
    • Barreiro, M.L.1    Tena-Sempere, M.2
  • 5
    • 67349227911 scopus 로고    scopus 로고
    • Ghrelin inhibits apoptosis induced by high glucose and sodium palmitate in adult rat cardiomycytes through the PI3K-Akt signaling pathway
    • Kui L., Weiwei Z., Ling L., Daikun H., Guoming Z., Linuo Z., Renming H. Ghrelin inhibits apoptosis induced by high glucose and sodium palmitate in adult rat cardiomycytes through the PI3K-Akt signaling pathway. Regul. Pept. 2009, 155:62-69.
    • (2009) Regul. Pept. , vol.155 , pp. 62-69
    • Kui, L.1    Weiwei, Z.2    Ling, L.3    Daikun, H.4    Guoming, Z.5    Linuo, Z.6    Renming, H.7
  • 6
    • 33846435771 scopus 로고    scopus 로고
    • Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic β-cells and human islets: involvement of 3,5-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2 and phosphatidyl inositol 3-kinase/Akt signaling
    • Granata R., Settanni F., Biancone L., Trovato L., Nano R., Bettuzzi F., Destefanis S., Annunziata M., Martinetti M., Catapano F., Ghe C., Isgaard J., Papotti M., Ghigo E., Muccioli G. Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic β-cells and human islets: involvement of 3,5-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2 and phosphatidyl inositol 3-kinase/Akt signaling. Endocrinology 2007, 148:512-529.
    • (2007) Endocrinology , vol.148 , pp. 512-529
    • Granata, R.1    Settanni, F.2    Biancone, L.3    Trovato, L.4    Nano, R.5    Bettuzzi, F.6    Destefanis, S.7    Annunziata, M.8    Martinetti, M.9    Catapano, F.10    Ghe, C.11    Isgaard, J.12    Papotti, M.13    Ghigo, E.14    Muccioli, G.15
  • 9
    • 0037784049 scopus 로고    scopus 로고
    • Ghrelin a novel growth hormone releasing peptide, in the treatment of chronic heart failure
    • Nagaya N., Kanagawa K. Ghrelin a novel growth hormone releasing peptide, in the treatment of chronic heart failure. Regul. Pept. 2003, 114:71-77.
    • (2003) Regul. Pept. , vol.114 , pp. 71-77
    • Nagaya, N.1    Kanagawa, K.2
  • 13
    • 33750723137 scopus 로고    scopus 로고
    • Bcl-2 expression as a predictivemarker of hormone-refractory prostate cancer treated with taxane-based chemotherapy
    • Yoshino T., Shina H., Urakami Sh., Kikuno N., Yoneda T., Shigeno K., Igawa M. Bcl-2 expression as a predictivemarker of hormone-refractory prostate cancer treated with taxane-based chemotherapy. Clin. Cancer Res. 2006, 12:6116-6124.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 6116-6124
    • Yoshino, T.1    Shina, H.2    Urakami, S.3    Kikuno, N.4    Yoneda, T.5    Shigeno, K.6    Igawa, M.7
  • 14
    • 0029903232 scopus 로고    scopus 로고
    • Apoptotic cell death in the normal and cryptorchid human testis: the effect of human chrionic gonadotropin on testicular cell survival
    • Heiskanen P., Billing H., Toppari J., Kaleva M., Arsalo A., Rapola J., Dunkel L. Apoptotic cell death in the normal and cryptorchid human testis: the effect of human chrionic gonadotropin on testicular cell survival. Pediatr. Res. 1996, 40:351-356.
    • (1996) Pediatr. Res. , vol.40 , pp. 351-356
    • Heiskanen, P.1    Billing, H.2    Toppari, J.3    Kaleva, M.4    Arsalo, A.5    Rapola, J.6    Dunkel, L.7
  • 16
    • 4544298249 scopus 로고    scopus 로고
    • Mitochondrial mechanisms of neural cell apoptosis
    • Polster B.M., Fiskum G. Mitochondrial mechanisms of neural cell apoptosis. J. Neurochem. 2004, 90:1281-1289.
    • (2004) J. Neurochem. , vol.90 , pp. 1281-1289
    • Polster, B.M.1    Fiskum, G.2
  • 17
    • 0034463078 scopus 로고    scopus 로고
    • Bcl-w forms complexes with Bax and Bak, and elevated ratios of Bax/Bcl-w and Bak/Bcl-w correspond to spermatogonia and spermatocyte apoptosis in the testis
    • Yan W., Samson M., Jegou B., Toppari J. Bcl-w forms complexes with Bax and Bak, and elevated ratios of Bax/Bcl-w and Bak/Bcl-w correspond to spermatogonia and spermatocyte apoptosis in the testis. Mol. Endocrinol. 2000, 14:682-699.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 682-699
    • Yan, W.1    Samson, M.2    Jegou, B.3    Toppari, J.4
  • 18
    • 0030975776 scopus 로고    scopus 로고
    • An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis
    • Rodriguez I., Ody C., Araki K., Garcia I., Vassalli P. An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis. EMBO J. 1997, 16:2262-2270.
    • (1997) EMBO J. , vol.16 , pp. 2262-2270
    • Rodriguez, I.1    Ody, C.2    Araki, K.3    Garcia, I.4    Vassalli, P.5
  • 20
    • 79956150435 scopus 로고    scopus 로고
    • Role of ghrelin on testosterone secretion and the mRNA expression of androgen receptors in adult rat testis
    • Wang L., Fang F., Li Y., Zhang Y., Pu Y., Zhang X. Role of ghrelin on testosterone secretion and the mRNA expression of androgen receptors in adult rat testis. Syst. Biol. Reprod. Med. 2011, 57:119-123.
    • (2011) Syst. Biol. Reprod. Med. , vol.57 , pp. 119-123
    • Wang, L.1    Fang, F.2    Li, Y.3    Zhang, Y.4    Pu, Y.5    Zhang, X.6
  • 21
    • 0028837040 scopus 로고
    • Apoptosis in the testis germ cells: developmental changes in gonadotropin dependence and localization to selective tubule stages
    • Billing H., Furuta I., Rivier C., Tapanainen J., Parvinen M., Hsueh A.J.W. Apoptosis in the testis germ cells: developmental changes in gonadotropin dependence and localization to selective tubule stages. Endocrinology 1995, 136:5-12.
    • (1995) Endocrinology , vol.136 , pp. 5-12
    • Billing, H.1    Furuta, I.2    Rivier, C.3    Tapanainen, J.4    Parvinen, M.5    Hsueh, A.J.W.6
  • 22
    • 0029121708 scopus 로고
    • Testosterone inhibits and induces apoptosis in rat seminiferous tubules in a stage-specific manner: in situ quantification in squash preparations after administration of ethane dimethane sulfonate
    • Henriksen H., Hakovitra H., Parvinen M. Testosterone inhibits and induces apoptosis in rat seminiferous tubules in a stage-specific manner: in situ quantification in squash preparations after administration of ethane dimethane sulfonate. Endocrinology 1995, 136:3285-3289.
    • (1995) Endocrinology , vol.136 , pp. 3285-3289
    • Henriksen, H.1    Hakovitra, H.2    Parvinen, M.3
  • 23
    • 0029030962 scopus 로고
    • Involvement of apoptosis in adult rats after gonadotropin-releasing hormone antagonist treatment
    • Hikim A.P.S., Wang C., Leung A., Swerdloff R.S. Involvement of apoptosis in adult rats after gonadotropin-releasing hormone antagonist treatment. Endocrinology 1995, 136:2770-2775.
    • (1995) Endocrinology , vol.136 , pp. 2770-2775
    • Hikim, A.P.S.1    Wang, C.2    Leung, A.3    Swerdloff, R.S.4
  • 26
    • 60749105018 scopus 로고    scopus 로고
    • The role of ghrelin on the morphometry and intracellular changes in the rat testis
    • Kheradmand A., Roshangar L., Taati M. The role of ghrelin on the morphometry and intracellular changes in the rat testis. Tissue Cell 2009, 41:105-111.
    • (2009) Tissue Cell , vol.41 , pp. 105-111
    • Kheradmand, A.1    Roshangar, L.2    Taati, M.3
  • 27
    • 70049087380 scopus 로고    scopus 로고
    • Morphometrical and intracellular changes in rat ovaries following chronic administration of ghrelin
    • Kheradmand A., Roshangar L., Taati M., Sirotkin A.V. Morphometrical and intracellular changes in rat ovaries following chronic administration of ghrelin. Tissue Cell 2009, 41:311-317.
    • (2009) Tissue Cell , vol.41 , pp. 311-317
    • Kheradmand, A.1    Roshangar, L.2    Taati, M.3    Sirotkin, A.V.4
  • 28
    • 0036199876 scopus 로고    scopus 로고
    • Bax-dependent spermatogonia apoptosis is required for testicular development and spermatogenesis
    • Russell L.D., Chiarini-Garcia H., Korsmeyer S.J., Knudson C.M. Bax-dependent spermatogonia apoptosis is required for testicular development and spermatogenesis. Biol. Reprod. 2002, 66:950-958.
    • (2002) Biol. Reprod. , vol.66 , pp. 950-958
    • Russell, L.D.1    Chiarini-Garcia, H.2    Korsmeyer, S.J.3    Knudson, C.M.4
  • 30
    • 0034077189 scopus 로고    scopus 로고
    • Roles of caspases in apoptosis, development, and cytokine maturation revealed by homozygous gene deficiencies
    • Wang J., Lenardo M.J. Roles of caspases in apoptosis, development, and cytokine maturation revealed by homozygous gene deficiencies. J. Cell Sci. 2000, 113:753-757.
    • (2000) J. Cell Sci. , vol.113 , pp. 753-757
    • Wang, J.1    Lenardo, M.J.2
  • 31
    • 58449103629 scopus 로고    scopus 로고
    • Modulatory effect of ghrelin in prepubertal porcine ovarian follicles
    • Rak A., Gregoraszczuk E.L. Modulatory effect of ghrelin in prepubertal porcine ovarian follicles. J. Physiol. Pharmacol. 2008, 59:781-793.
    • (2008) J. Physiol. Pharmacol. , vol.59 , pp. 781-793
    • Rak, A.1    Gregoraszczuk, E.L.2
  • 32
    • 66449088834 scopus 로고    scopus 로고
    • Growth hormone-releasing peptide 6 protection of hypothalamic neurons from glutamate excitotoxicity is caspase independent and not mediated by insulin-like growth factor I
    • Delgado-Rubin A., Chowen J.A., Argente J., Frago L.M. Growth hormone-releasing peptide 6 protection of hypothalamic neurons from glutamate excitotoxicity is caspase independent and not mediated by insulin-like growth factor I. Eur. J. Neurosci. 2009, 29:2115-2124.
    • (2009) Eur. J. Neurosci. , vol.29 , pp. 2115-2124
    • Delgado-Rubin, A.1    Chowen, J.A.2    Argente, J.3    Frago, L.M.4
  • 34
    • 9244247597 scopus 로고    scopus 로고
    • Ghrelin inhibits the proliferative activity of immature Leydig cells in vitro and regulates stem cell factor messenger ribonucleic acid expression in rat testis
    • Barreiro M.L., Gaytan F., Castellano J.M., Suominen J.S., Roa J., Gaytan M., Aguilar E., Dieguez C., Toppari J., Tena-Sempere M. Ghrelin inhibits the proliferative activity of immature Leydig cells in vitro and regulates stem cell factor messenger ribonucleic acid expression in rat testis. Endocrinology 2004, 145:4825-4834.
    • (2004) Endocrinology , vol.145 , pp. 4825-4834
    • Barreiro, M.L.1    Gaytan, F.2    Castellano, J.M.3    Suominen, J.S.4    Roa, J.5    Gaytan, M.6    Aguilar, E.7    Dieguez, C.8    Toppari, J.9    Tena-Sempere, M.10
  • 36
    • 0032914010 scopus 로고    scopus 로고
    • Function of stem cell factor as a survival factor of spermatogonia and localization of messenger ribonucleic acid in the rat seminiferous epithelium
    • Hakovitra H., Yan W., Kaleva M., Zhang F., Vanttinen K., Morris P.L., Soder M., Parvinen M., Toppari J. Function of stem cell factor as a survival factor of spermatogonia and localization of messenger ribonucleic acid in the rat seminiferous epithelium. Endocrinology 1999, 140:1492-1498.
    • (1999) Endocrinology , vol.140 , pp. 1492-1498
    • Hakovitra, H.1    Yan, W.2    Kaleva, M.3    Zhang, F.4    Vanttinen, K.5    Morris, P.L.6    Soder, M.7    Parvinen, M.8    Toppari, J.9


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