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Volumn 26, Issue 3, 2012, Pages 390-394

How to manage lower-risk myelodysplastic syndromes

Author keywords

MDS; outcomes; therapy

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; LENALIDOMIDE; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; THYMOCYTE ANTIBODY;

EID: 84857992233     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.223     Document Type: Review
Times cited : (7)

References (57)
  • 1
    • 0019952276 scopus 로고
    • Proposals for the classification of the myelodysplastic syndromes
    • Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR et al. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 1982; 51: 189-199. (Pubitemid 12073508)
    • (1982) British Journal of Haematology , vol.51 , Issue.2 , pp. 189-199
    • Bennett, J.M.1    Catovsky, D.2    Daniel, M.T.3
  • 2
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 Revisions of the WHO classification of myeloid neoplasms and acute leukemia: Rationale and important changes
    • Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A et al. The 2008 Revisions of the WHO classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood 2009; 114: 937-951.
    • (2009) Blood , vol.114 , pp. 937-951
    • Vardiman, J.W.1    Thiele, J.2    Arber, D.A.3    Brunning, R.D.4    Borowitz, M.J.5    Porwit, A.6
  • 4
    • 0035283119 scopus 로고    scopus 로고
    • Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes
    • DOI 10.1182/blood.V97.5.1427
    • Bellamy WT, Richter L, Sirjani D, Roxas C, Glinsmann-Gibson B, Frutiger Y et al. Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes. Blood 2001; 97: 1427-1434. (Pubitemid 32183769)
    • (2001) Blood , vol.97 , Issue.5 , pp. 1427-1434
    • Bellamy, W.T.1    Richter, L.2    Sirjani, D.3    Roxas, C.4    Glinsmann-Gibson, B.5    Frutiger, Y.6    Grogan, T.M.7    List, A.F.8
  • 5
    • 0031464758 scopus 로고    scopus 로고
    • Overexpression of tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma by bone marrow cells from patients with myelodysplastic syndromes
    • Kitagawa M, Saito I, Kuwata T, Yoshida S, Yamaguchi S, Takahashi M et al. Overexpression of tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma by bone marrow cells from patients with myelodysplastic syndromes. Leukemia 1997; 11: 2049-2054. (Pubitemid 28043688)
    • (1997) Leukemia , vol.11 , Issue.12 , pp. 2049-2054
    • Kitagawa, M.1    Saito, I.2    Kuwata, T.3    Yoshida, S.4    Yamaguchi, S.5    Takahashi, M.6    Tanizawa, T.7    Kamiyama, R.8    Hirokawa, K.9
  • 6
    • 60849089645 scopus 로고    scopus 로고
    • Aberrant DNA methylation is a dominant mechanism in MDS progression to AML
    • Jiang Y, Dunbar A, Gondek LP, Mohan S, Rataul M, O'Keefe C et al. Aberrant DNA methylation is a dominant mechanism in MDS progression to AML. Blood 2009; 113: 1315-1325.
    • (2009) Blood , vol.113 , pp. 1315-1325
    • Jiang, Y.1    Dunbar, A.2    Gondek, L.P.3    Mohan, S.4    Rataul, M.5    O'Keefe, C.6
  • 7
    • 79955945973 scopus 로고    scopus 로고
    • Prognostic impact of SNP array karyotyping in myelodys-plastic syndromes and related myeloid malignancies
    • Tiu RV, Gondek LP, O'Keefe CL, Elson P, Huh J, Mohamedali A et al. Prognostic impact of SNP array karyotyping in myelodys-plastic syndromes and related myeloid malignancies. Blood 2011; 117: 4552-4560.
    • (2011) Blood , vol.117 , pp. 4552-4560
    • Tiu, R.V.1    Gondek, L.P.2    O'Keefe, C.L.3    Elson, P.4    Huh, J.5    Mohamedali, A.6
  • 8
    • 34247172535 scopus 로고    scopus 로고
    • Myelodysplastic syndromes: Incidence and survival in the United States
    • DOI 10.1002/cncr.22570
    • Ma X, Does M, Raza A, Mayne ST. Myelodysplastic syndromes: incidence and survival in the United States. Cancer 2007; 109: 1536-1542. (Pubitemid 46595689)
    • (2007) Cancer , vol.109 , Issue.8 , pp. 1536-1542
    • Ma, X.1    Does, M.2    Raza, A.3    Mayne, S.T.4
  • 9
    • 47249150213 scopus 로고    scopus 로고
    • Epidemiology of myelodysplastic syndromes and chronic myeloproliferative disorders in the United States, 2001-2004, using data from the NAACCR and SEER programs
    • Rollison DE, Howlader N, Smith MT, Strom SS, Merritt WD, Ries LA et al. Epidemiology of myelodysplastic syndromes and chronic myeloproliferative disorders in the United States, 2001-2004, using data from the NAACCR and SEER programs. Blood 2008; 112: 45-52.
    • (2008) Blood , vol.112 , pp. 45-52
    • Rollison, D.E.1    Howlader, N.2    Smith, M.T.3    Strom, S.S.4    Merritt, W.D.5    Ries, L.A.6
  • 10
    • 0026688084 scopus 로고
    • Age-related incidence and other epidemiological aspects of myelodysplastic syndromes
    • Aul C, Gattermann N, Schneider W. Age-related incidence and other epidemiological aspects of myelodysplastic syndromes. Br J Haematol 1992; 82: 358-367.
    • (1992) Br J Haematol , vol.82 , pp. 358-367
    • Aul, C.1    Gattermann, N.2    Schneider, W.3
  • 12
    • 0031398164 scopus 로고    scopus 로고
    • Age and sex distributions of hematological malignancies in the U.K.
    • DOI 10.1002/(SICI)1099-1069(199711)15:4<173::AID-HON610>3.0.CO;2-K
    • McNally RJ, Rowland D, Roman E, Cartwright RA. Age and sex distributions of hematological malignancies in the UK. Hematol Oncol 1997; 15: 173-189. (Pubitemid 28374886)
    • (1997) Hematological Oncology , vol.15 , Issue.4 , pp. 173-189
    • McNally, R.J.Q.1    Rowland, D.2    Roman, E.3    Cartwright, R.A.4
  • 14
    • 55749114037 scopus 로고    scopus 로고
    • Characteristics of USA patients with myelodysplastic syndromes: Results of six cross-sectional physician surveys
    • Sekeres MA, Schoonen WM, Kantarjian H, List A, Fryzek J, Paquette R et al. Characteristics of USA patients with myelodysplastic syndromes: results of six cross-sectional physician surveys. J Natl Cancer Inst 2008; 100: 1542-1551.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1542-1551
    • Sekeres, M.A.1    Schoonen, W.M.2    Kantarjian, H.3    List, A.4    Fryzek, J.5    Paquette, R.6
  • 15
    • 53149113768 scopus 로고    scopus 로고
    • Proposal for a new risk model in myelodysplastic syndrome that accounts for events not considered in the original International Prognostic Scoring System
    • Kantarjian H, O'Brien S, Ravandi F, Cortes J, Shan J, Bennett JM et al. Proposal for a new risk model in myelodysplastic syndrome that accounts for events not considered in the original International Prognostic Scoring System. Cancer 2008; 113: 1351-1361.
    • (2008) Cancer , vol.113 , pp. 1351-1361
    • Kantarjian, H.1    O'Brien, S.2    Ravandi, F.3    Cortes, J.4    Shan, J.5    Bennett, J.M.6
  • 17
    • 79959586108 scopus 로고    scopus 로고
    • Perceptions of disease state, treatment outcomes, and prognosis among patients with myelodysplastic syndromes: Results from an internet-based survey
    • Sekeres MA, Maciejewski JP, List AF, Steensma DP, Artz A, Swern AS et al. Perceptions of disease state, treatment outcomes, and prognosis among patients with myelodysplastic syndromes: results from an internet-based survey. Oncologist 2011; 16: 904-911.
    • (2011) Oncologist , vol.16 , pp. 904-911
    • Sekeres, M.A.1    Maciejewski, J.P.2    List, A.F.3    Steensma, D.P.4    Artz, A.5    Swern, A.S.6
  • 22
    • 0032409909 scopus 로고    scopus 로고
    • A randomized double-blind placebo-controlled study with subcutaneous recombinant human erythropoietin in patients with low-risk myelodysplastic syndromes
    • Italian cooperative study group for rHuEpo in myelodysplastic syndromes
    • A randomized double-blind placebo-controlled study with subcutaneous recombinant human erythropoietin in patients with low-risk myelodysplastic syndromes. Italian cooperative study group for rHuEpo in myelodysplastic syndromes. Br J Haematol 1998; 103: 1070-1074.
    • (1998) Br J Haematol , vol.103 , pp. 1070-1074
  • 25
    • 0029940725 scopus 로고    scopus 로고
    • Maintenance treatment of the anemia of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor and erythropoietin: Evidence for in vivo synergy
    • Negrin RS, Stein R, Doherty K, Cornwell J, Vardiman J, Krantz S et al. Maintenance treatment of the anemia of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor and erythropoietin: evidence for in vivo synergy. Blood 1996; 87: 4076-4081. (Pubitemid 26152251)
    • (1996) Blood , vol.87 , Issue.10 , pp. 4076-4081
    • Negrin, R.S.1    Stein, R.2    Doherty, K.3    Cornwall, J.4    Vardiman, J.5    Krantz, S.6    Greenberg, P.L.7
  • 27
    • 0034043581 scopus 로고    scopus 로고
    • Treatment of anaemia in myelodysplastic syndromes with prolonged administration of recombinant human granulocyte colony-stimulating factor and erythropoietin
    • DOI 10.1046/j.1365-2141.2000.02016.x
    • Mantovani L, Lentini G, Hentschel B, Wickramanayake PD, Loeffler M, Diehl V et al. Treatment of anaemia in myelodysplastic syndromes with prolonged administration of recombinant human granulocyte colony-stimulating factor and erythropoietin. Br J Haematol 2000; 109: 367-375. (Pubitemid 30350720)
    • (2000) British Journal of Haematology , vol.109 , Issue.2 , pp. 367-375
    • Mantovani, L.1    Lentini, G.2    Hentschel, B.3    Wickramanayake, P.D.4    Loeffler, M.5    Diehl, V.6    Tesch, H.7
  • 28
    • 23044440179 scopus 로고    scopus 로고
    • Long-term outcome of treatment of anemia in MDS with erythropoietin and G-CSF
    • DOI 10.1182/blood-2004-10-3872
    • Jadersten M, Montgomery SM, Dybedal I, Porwit-MacDonald A, Hellstrom-Lindberg E. Long-term outcome of treatment of anemia in MDS with erythropoietin and G-CSF. Blood 2005; 106: 803-811. (Pubitemid 41076418)
    • (2005) Blood , vol.106 , Issue.3 , pp. 803-811
    • Jadersten, M.1    Montgomery, S.M.2    Dybedal, I.3    Porwit-MacDonald, A.4    Hellstrom-Lindberg, E.5
  • 29
    • 0028953367 scopus 로고
    • Efficacy of erythropoietin in the myelodysplastic syndromes: A meta-analysis of 205 patients from 17 studies
    • Hellstrom-Lindberg E. Efficacy of erythropoietin in the myelodysplastic syndromes: a meta-analysis of 205 patients from 17 studies. Br J Haematol 1995; 89: 67-71.
    • (1995) Br J Haematol , vol.89 , pp. 67-71
    • Hellstrom-Lindberg, E.1
  • 30
    • 49049116574 scopus 로고    scopus 로고
    • Erythropoietin and granulocytecolony stimulating factor treatment associated with improved survival in myelodysplastic syndrome
    • Jadersten M, Malcovati L, Dybedal I, Della Porta MG, Invernizzi R, Montgomery SM et al. Erythropoietin and granulocytecolony stimulating factor treatment associated with improved survival in myelodysplastic syndrome. J Clin Oncol 2008; 26: 3607-3613.
    • (2008) J Clin Oncol , vol.26 , pp. 3607-3613
    • Jadersten, M.1    Malcovati, L.2    Dybedal, I.3    Della Porta, M.G.4    Invernizzi, R.5    Montgomery, S.M.6
  • 31
    • 38349097652 scopus 로고    scopus 로고
    • Predictive factors of response and survival in myelodysplastic syndrome treated with erythropoietin and G-CSF: The GFM experience
    • Park S, Grabar S, Kelaidi C, Beyne-Rauzy O, Picard F, Bardet V et al. Predictive factors of response and survival in myelodysplastic syndrome treated with erythropoietin and G-CSF: the GFM experience. Blood 2008; 111: 574-582.
    • (2008) Blood , vol.111 , pp. 574-582
    • Park, S.1    Grabar, S.2    Kelaidi, C.3    Beyne-Rauzy, O.4    Picard, F.5    Bardet, V.6
  • 33
    • 0030682515 scopus 로고    scopus 로고
    • Erythroid response to treatment with G-CSF plus erythropoietin for the anaemia of patients with myelodysplastic syndromes: Proposal for a predictive model
    • Hellstrom-Lindberg E, Negrin R, Stein R, Krantz S, Lindberg G, Vardiman J et al. Erythroid response to treatment with G-CSF plus erythropoietin for the anaemia of patients with myelodysplastic syndromes: proposal for a predictive model. Br J Haematol 1997; 99: 344-351. (Pubitemid 27497565)
    • (1997) British Journal of Haematology , vol.99 , Issue.2 , pp. 344-351
    • Hellstrom-Lindberg, E.1    Negrin, R.2    Stein, R.3    Krantz, S.4    Lindberg, G.5    Vardiman, J.6    Ost, A.7    Greenberg, P.8
  • 35
    • 33947260567 scopus 로고    scopus 로고
    • A decision analysis to determine the appropriate treatment for low-risk myelodysplastic syndromes
    • DOI 10.1002/cncr.22497
    • Sekeres MA, Fu AZ, Maciejewski JP, Golshayan AR, Kalaycio ME, Kattan MW. A decision analysis to determine the appropriate treatment for low-risk myelodysplastic syndromes. Cancer 2007; 109: 1125-1132. (Pubitemid 46435391)
    • (2007) Cancer , vol.109 , Issue.6 , pp. 1125-1132
    • Sekeres, M.A.1    Fu, A.Z.2    Maciejewski, J.P.3    Golshayan, A.-R.4    Kalaycio, M.E.5    Kattan, M.W.6
  • 37
    • 69149090140 scopus 로고    scopus 로고
    • A critical role for phosphatase haplodeficiency in the selective suppression of deletion 5q MDS by lenalidomide
    • Wei S, Chen X, Rocha K, Epling-Burnette PK, Djeu JY, Liu Q et al. A critical role for phosphatase haplodeficiency in the selective suppression of deletion 5q MDS by lenalidomide. Proc Natl Acad Sci USA 2009; 106: 12974-12979.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 12974-12979
    • Wei, S.1    Chen, X.2    Rocha, K.3    Epling-Burnette, P.K.4    Djeu, J.Y.5    Liu, Q.6
  • 38
    • 38349088899 scopus 로고    scopus 로고
    • Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
    • Ebert BL, Pretz J, Bosco J, Chang CY, Tamayo P, Galili N et al. Identification of RPS14 as a 5q- syndrome gene by RNA interference screen. Nature 2008; 451: 335-339.
    • (2008) Nature , vol.451 , pp. 335-339
    • Ebert, B.L.1    Pretz, J.2    Bosco, J.3    Chang, C.Y.4    Tamayo, P.5    Galili, N.6
  • 40
    • 58049221263 scopus 로고    scopus 로고
    • Relationship of treatment-related cytopenias and response to lenalidomide in patients with lower-risk myelodysplastic syndromes
    • Sekeres MA, Maciejewski JP, Giagounidis AA, Wride K, Knight R, Raza A et al. Relationship of treatment-related cytopenias and response to lenalidomide in patients with lower-risk myelodysplastic syndromes. J Clin Oncol 2008; 26: 5943-5949.
    • (2008) J Clin Oncol , vol.26 , pp. 5943-5949
    • Sekeres, M.A.1    Maciejewski, J.P.2    Giagounidis, A.A.3    Wride, K.4    Knight, R.5    Raza, A.6
  • 41
    • 38049113182 scopus 로고    scopus 로고
    • Phase 2 study of lenalidomide in transfusion-dependent, low-risk, and intermediate-1 risk myelodysplastic syndromes with karyotypes other than deletion 5q
    • Raza A, Reeves JA, Feldman EJ, Dewald GW, Bennett JM, Deeg HJ et al. Phase 2 study of lenalidomide in transfusion-dependent, low-risk, and intermediate-1 risk myelodysplastic syndromes with karyotypes other than deletion 5q. Blood 2008; 111: 86-93.
    • (2008) Blood , vol.111 , pp. 86-93
    • Raza, A.1    Reeves, J.A.2    Feldman, E.J.3    Dewald, G.W.4    Bennett, J.M.5    Deeg, H.J.6
  • 42
    • 78651247688 scopus 로고    scopus 로고
    • Survival, prognostic factors, and rates of leukemic transformation in a multicenter study of 303 untreated patients with MDS and del(5q)
    • Germing U, Lauseker M, Hildebrandt B, Symeonidis A, Cermak J, Pfeilstocker M et al. Survival, prognostic factors, and rates of leukemic transformation in a multicenter study of 303 untreated patients with MDS and del(5q). ASH Annual Meeting Abstracts 2009; 114: 945.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 945
    • Germing, U.1    Lauseker, M.2    Hildebrandt, B.3    Symeonidis, A.4    Cermak, J.5    Pfeilstocker, M.6
  • 43
  • 44
    • 75749124291 scopus 로고    scopus 로고
    • Safety and efficacy of romiplostim in patients with lower-risk myelodysplastic syndrome and thrombocytopenia
    • Kantarjian H, Fenaux P, Sekeres MA, Becker PS, Boruchov A, Bowen D et al. Safety and efficacy of romiplostim in patients with lower-risk myelodysplastic syndrome and thrombocytopenia. J Clin Oncol 2009; 28: 437-444.
    • (2009) J Clin Oncol , vol.28 , pp. 437-444
    • Kantarjian, H.1    Fenaux, P.2    Sekeres, M.A.3    Becker, P.S.4    Boruchov, A.5    Bowen, D.6
  • 45
    • 79952011926 scopus 로고    scopus 로고
    • Subcutaneous or intravenous administration of romiplostim in thrombocytopenic patients with lower risk myelodysplastic syndromes
    • Sekeres MA, Kantarjian H, Fenaux P, Becker P, Boruchov A, Guerci-Bresler A et al. Subcutaneous or intravenous administration of romiplostim in thrombocytopenic patients with lower risk myelodysplastic syndromes. Cancer 2011; 117: 992-1000.
    • (2011) Cancer , vol.117 , pp. 992-1000
    • Sekeres, M.A.1    Kantarjian, H.2    Fenaux, P.3    Becker, P.4    Boruchov, A.5    Guerci-Bresler, A.6
  • 46
    • 79951996237 scopus 로고    scopus 로고
    • Immunosuppressive therapy for patients with myelodysplastic syndrome: A prospective randomized multicenter phase III trial comparing antithymocyte globulin plus cyclosporine with best supportive care-SAKK 33/99
    • Passweg JR, Giagounidis AA, Simcock M, Aul C, Dobbelstein C, Stadler M et al. Immunosuppressive therapy for patients with myelodysplastic syndrome: a prospective randomized multicenter phase III trial comparing antithymocyte globulin plus cyclosporine with best supportive care-SAKK 33/99. J Clin Oncol 2011; 29: 303-309.
    • (2011) J Clin Oncol , vol.29 , pp. 303-309
    • Passweg, J.R.1    Giagounidis, A.A.2    Simcock, M.3    Aul, C.4    Dobbelstein, C.5    Stadler, M.6
  • 47
    • 0141923848 scopus 로고    scopus 로고
    • A simple method to predict response to immunosuppressive therapy in patients with myelodysplastic syndrome
    • DOI 10.1182/blood-2002-11-3325
    • Saunthararajah Y, Nakamura R, Wesley R, Wang QJ, Barrett AJ. A simple method to predict response to immunosuppressive therapy in patients with myelodysplastic syndrome. Blood 2003; 102: 3025-3027. (Pubitemid 37248879)
    • (2003) Blood , vol.102 , Issue.8 , pp. 3025-3027
    • Saunthararajah, Y.1    Nakamura, R.2    Wesley, R.3    Wang, Q.J.4    Barrett, A.J.5
  • 48
    • 77955173236 scopus 로고    scopus 로고
    • A study comparing dosing regimens and efficacy of subcutaneous to intravenous azacitidine (AZA) for the treatment of myelodysplastic syndromes (MDS)
    • Sekeres MA, Maciejewski JP, Donley DW, Grinblatt DL, Narang M, Malone III JM et al. A study comparing dosing regimens and efficacy of subcutaneous to intravenous azacitidine (AZA) for the treatment of myelodysplastic syndromes (MDS). ASH Annual Meeting Abstracts 2009; 114: 3797.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 3797
    • Sekeres, M.A.1    Maciejewski, J.P.2    Donley, D.W.3    Grinblatt, D.L.4    Narang, M.5    Malone III, J.M.6
  • 49
    • 79957510305 scopus 로고    scopus 로고
    • The relevance of iron overload and the appropriateness of iron chelation therapy for patients with myelodysplastic syndromes: A dialogue and debate
    • Steensma DP. The relevance of iron overload and the appropriateness of iron chelation therapy for patients with myelodysplastic syndromes: a dialogue and debate. Curr Hematol Malig Rep 2011; 6: 136-144.
    • (2011) Curr Hematol Malig Rep , vol.6 , pp. 136-144
    • Steensma, D.P.1
  • 50
    • 78951487148 scopus 로고    scopus 로고
    • The role of iron chelation therapy for patients with myelodysplastic syndromes
    • Steensma DP. The role of iron chelation therapy for patients with myelodysplastic syndromes. J Natl Compr Canc Netw 2011; 9: 65-75.
    • (2011) J Natl Compr Canc Netw , vol.9 , pp. 65-75
    • Steensma, D.P.1
  • 51
    • 67549104444 scopus 로고    scopus 로고
    • Myelodysplasia paranoia: Iron as the new radon
    • Steensma DP. Myelodysplasia paranoia: iron as the new radon. Leuk Res 2009; 33: 1158-1163.
    • (2009) Leuk Res , vol.33 , pp. 1158-1163
    • Steensma, D.P.1
  • 52
    • 68749110767 scopus 로고    scopus 로고
    • Iron chelation therapy in myelodysplastic syndromeFcui bono?
    • Tefferi A, Stone RM. Iron chelation therapy in myelodysplastic syndromeFcui bono? Leukemia 2009; 23: 1373.
    • (2009) Leukemia , vol.23 , pp. 1373
    • Tefferi, A.1    Stone, R.M.2
  • 54
    • 69249238115 scopus 로고    scopus 로고
    • Phase 1 multicenter dose-escalation study of ezatiostat hydrochloride (TelintraTM, TLK199 tablets), a novel glutathione analog prodrug, in patients with myelodysplastic syndrome
    • Raza A, Galili N, Smith S, Godwin J, Lancet J, Melchert M et al. Phase 1 multicenter dose-escalation study of ezatiostat hydrochloride (TelintraTM, TLK199 tablets), a novel glutathione analog prodrug, in patients with myelodysplastic syndrome. Blood 2009; 113: 6533-6540.
    • (2009) Blood , vol.113 , pp. 6533-6540
    • Raza, A.1    Galili, N.2    Smith, S.3    Godwin, J.4    Lancet, J.5    Melchert, M.6
  • 56
    • 78650354414 scopus 로고    scopus 로고
    • Alemtuzumab treatment of intermediate-1 myelodysplasia patients is associated with sustained improvement in blood counts and cytogenetic remissions
    • Sloand EM, Olnes MJ, Shenoy A, Weinstein B, Boss C, Loeliger K et al. Alemtuzumab treatment of intermediate-1 myelodysplasia patients is associated with sustained improvement in blood counts and cytogenetic remissions. J Clin Oncol 2010; 28: 5166-5173.
    • (2010) J Clin Oncol , vol.28 , pp. 5166-5173
    • Sloand, E.M.1    Olnes, M.J.2    Shenoy, A.3    Weinstein, B.4    Boss, C.5    Loeliger, K.6
  • 57
    • 84857997081 scopus 로고    scopus 로고
    • Siltuximab treatment increases hemoglobin (Hb) levels: Preliminary results from a prospective phase 1 study in refractory solid tumors
    • Kurzrock R, Angevin E, Cohen S, Van Laethem J, Rijnbeek B, Vermeulen J et al. Siltuximab treatment increases hemoglobin (Hb) levels: preliminary results from a prospective phase 1 study in refractory solid tumors. ASH Annual Meeting Abstracts 2010; 116: 5150.
    • (2010) ASH Annual Meeting Abstracts , vol.116 , pp. 5150
    • Kurzrock, R.1    Angevin, E.2    Cohen, S.3    Van Laethem, J.4    Rijnbeek, B.5    Vermeulen, J.6


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