-
1
-
-
0004851872
-
Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group
-
Black DM, Cummings SR, Karpf DB, Cauley JA, Thompson DE, Nevitt MC, et al. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet. 1996; 348: 1535-41.
-
(1996)
Lancet
, vol.348
, pp. 1535-1541
-
-
Black, D.M.1
Cummings, S.R.2
Karpf, D.B.3
Cauley, J.A.4
Thompson, D.E.5
Nevitt, M.C.6
-
2
-
-
0032583492
-
Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: Results from the Fracture Intervention Trial
-
Cummings SR, Black DM, Thompson DE, Applegate WB, Barrett- Connor E, Musliner TA, et al. Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA. 1998; 280: 2077-82.
-
(1998)
JAMA
, vol.280
, pp. 2077-2082
-
-
Cummings, S.R.1
Black, D.M.2
Thompson, D.E.3
Applegate, W.B.4
Barrett-Connor, E.5
Musliner, T.A.6
-
3
-
-
0033552255
-
Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: A randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group
-
Harris ST, Watts NB, Genant HK, McKeever CD, Hangartner T, Keller M, et al. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA. 1999; 282: 1344-52.
-
(1999)
JAMA
, vol.282
, pp. 1344-1352
-
-
Harris, S.T.1
Watts, N.B.2
Genant, H.K.3
McKeever, C.D.4
Hangartner, T.5
Keller, M.6
-
4
-
-
12944291524
-
Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group
-
Reginster J, Minne HW, Sorensen OH, Hooper M, Roux C, Brandi ML, et al. Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group. Osteoporos Int. 2000; 11: 83-91.
-
(2000)
Osteoporos Int
, vol.11
, pp. 83-91
-
-
Reginster, J.1
Minne, H.W.2
Sorensen, O.H.3
Hooper, M.4
Roux, C.5
Brandi, M.L.6
-
5
-
-
4544262219
-
Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis
-
Chesnut IC, Skag A, Christiansen C, Recker R, Stakkestad JA, Hoiseth A, et al. Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis. J Bone Miner Res. 2004; 19: 1241-9.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1241-1249
-
-
Chesnut, I.C.1
Skag, A.2
Christiansen, C.3
Recker, R.4
Stakkestad, J.A.5
Hoiseth, A.6
-
6
-
-
34247866550
-
Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis
-
Black DM, Delmas PD, Eastell R, Reid IR, Boonen S, Cauley JA, et al. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med. 2007; 356: 1809-22.
-
(2007)
N Engl J Med
, vol.356
, pp. 1809-1822
-
-
Black, D.M.1
Delmas, P.D.2
Eastell, R.3
Reid, I.R.4
Boonen, S.5
Cauley, J.A.6
-
7
-
-
63449137386
-
Risk of fracture in women treated with monthly oral ibandronate or weekly bisphosphonates: The eValuation of IBandronate Efficacy (VIBE) database fracture study
-
Harris ST, Reginster JY, Harley C, Blumentals WA, Poston SA, Barr CE, et al. Risk of fracture in women treated with monthly oral ibandronate or weekly bisphosphonates: the eValuation of IBandronate Efficacy (VIBE) database fracture study. Bone. 2009; 44: 758-65.
-
(2009)
Bone
, vol.44
, pp. 758-765
-
-
Harris, S.T.1
Reginster, J.Y.2
Harley, C.3
Blumentals, W.A.4
Poston, S.A.5
Barr, C.E.6
-
8
-
-
33845353443
-
Effectiveness of bisphosphonates on nonvertebral and hip fractures in the first year of therapy: The risedronate and alendronate (REAL) cohort study
-
Silverman SL, Watts NB, Delmas PD, Lange JL, Lindsay R. Effectiveness of bisphosphonates on nonvertebral and hip fractures in the first year of therapy: the risedronate and alendronate (REAL) cohort study. Osteoporos Int. 2007; 18: 25-34.
-
(2007)
Osteoporos Int
, vol.18
, pp. 25-34
-
-
Silverman, S.L.1
Watts, N.B.2
Delmas, P.D.3
Lange, J.L.4
Lindsay, R.5
-
9
-
-
77955094693
-
Absolute risk reduction in osteoporosis: Assessing treatment efficacy by number needed to treat
-
Ringe JD, Doherty JG. Absolute risk reduction in osteoporosis: assessing treatment efficacy by number needed to treat. Rheumatol Int. 2010; 30: 863-9.
-
(2010)
Rheumatol Int
, vol.30
, pp. 863-869
-
-
Ringe, J.D.1
Doherty, J.G.2
-
12
-
-
33845890326
-
Effects of continuing or stopping alendronate after 5 years of treatment: The Fracture Intervention Trial Long-term Extension (FLEX): A randomized trial
-
Black DM, Schwartz AV, Ensrud KE, Cauley JA, Levis S, Quandt SA, et al. Effects of continuing or stopping alendronate after 5 years of treatment: the Fracture Intervention Trial Long-term Extension (FLEX): a randomized trial. JAMA. 2006; 296: 2927-38.
-
(2006)
JAMA
, vol.296
, pp. 2927-2938
-
-
Black, D.M.1
Schwartz, A.V.2
Ensrud, K.E.3
Cauley, J.A.4
Levis, S.5
Quandt, S.A.6
-
13
-
-
1642526540
-
Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro
-
Thompson K, Rogers MJ. Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro. J Bone Miner Res. 2004; 19: 278-88.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 278-288
-
-
Thompson, K.1
Rogers, M.J.2
-
14
-
-
35748967004
-
Zoledronic acid and clinical fractures and mortality after hip fracture
-
Lyles KW, Colon-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C, et al. Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med. 2007; 357: 1799-809.
-
(2007)
N Engl J Med
, vol.357
, pp. 1799-1809
-
-
Lyles, K.W.1
Colon-Emeric, C.S.2
Magaziner, J.S.3
Adachi, J.D.4
Pieper, C.F.5
Mautalen, C.6
-
15
-
-
67650767002
-
Adverse effects of bisphosphonates: Implications for osteoporosis management
-
quiz 8
-
Kennel KA, Drake MT. Adverse effects of bisphosphonates: implications for osteoporosis management. Mayo Clin Proc. 2009; 84: 632-7; quiz 8.
-
(2009)
Mayo Clin Proc
, vol.84
, pp. 632-637
-
-
Kennel, K.A.1
Drake, M.T.2
-
16
-
-
33751528987
-
Osteonecrosis of the jaw--do bisphosphonates pose a risk?
-
Bilezikian JP. Osteonecrosis of the jaw--do bisphosphonates pose a risk? N Engl J Med. 2006; 355: 2278-81.
-
(2006)
N Engl J Med
, vol.355
, pp. 2278-2281
-
-
Bilezikian, J.P.1
-
17
-
-
41949097526
-
Osteonecrosis of the jaw and bisphosphonate treatment for osteoporosis
-
Rizzoli R, Burlet N, Cahall D, Delmas PD, Eriksen EF, Felsenberg D, et al. Osteonecrosis of the jaw and bisphosphonate treatment for osteoporosis. Bone. 2008; 42: 841-7.
-
(2008)
Bone
, vol.42
, pp. 841-847
-
-
Rizzoli, R.1
Burlet, N.2
Cahall, D.3
Delmas, P.D.4
Eriksen, E.F.5
Felsenberg, D.6
-
18
-
-
67651233516
-
Bone turnover in bone biopsies of patients with low-energy cortical fractures receiving bisphosphonates: A case series
-
Armamento-Villareal R, Napoli N, Diemer K, Watkins M, Civitelli R, Teitelbaum S, et al. Bone turnover in bone biopsies of patients with low-energy cortical fractures receiving bisphosphonates: a case series. Calcif Tissue Int. 2009; 85: 37-44.
-
(2009)
Calcif Tissue Int
, vol.85
, pp. 37-44
-
-
Armamento-Villareal, R.1
Napoli, N.2
Diemer, K.3
Watkins, M.4
Civitelli, R.5
Teitelbaum, S.6
-
19
-
-
15944413442
-
Severely suppressed bone turnover: A potential complication of alendronate therapy
-
Odvina CV, Zerwekh JE, Rao DS, Maalouf N, Gottschalk FA, Pak CY. Severely suppressed bone turnover: a potential complication of alendronate therapy. J Clin Endocrinol Metab. 2005; 90: 1294-301.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 1294-1301
-
-
Odvina, C.V.1
Zerwekh, J.E.2
Rao, D.S.3
Maalouf, N.4
Gottschalk, F.A.5
Pak, C.Y.6
-
20
-
-
58249090943
-
Reports of esophageal cancer with oral bisphosphonate use
-
Wysowski DK. Reports of esophageal cancer with oral bisphosphonate use. N Engl J Med. 2009; 360: 89-90.
-
(2009)
N Engl J Med
, vol.360
, pp. 89-90
-
-
Wysowski, D.K.1
-
22
-
-
77955870208
-
Use of bisphosphonates and risk of postmenopausal breast cancer
-
Rennert G, Pinchev M, Rennert HS. Use of bisphosphonates and risk of postmenopausal breast cancer. J Clin Oncol. 2010; 28: 3577-81.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3577-3581
-
-
Rennert, G.1
Pinchev, M.2
Rennert, H.S.3
-
23
-
-
77955875028
-
Oral bisphosphonate use and breast cancer incidence in postmenopausal women
-
Chlebowski RT, Chen Z, Cauley JA, Anderson G, Rodabough RJ, Mc- Tiernan A, et al. Oral bisphosphonate use and breast cancer incidence in postmenopausal women. J Clin Oncol. 2010; 28: 3582-90.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3582-3590
-
-
Chlebowski, R.T.1
Chen, Z.2
Cauley, J.A.3
Anderson, G.4
Rodabough, R.J.5
Mc-Tiernan, A.6
-
24
-
-
84855700197
-
Exposure to bisphosphonates and risk of colorectal cancer: A population-based nested case-control study
-
[Epub ahead of print]
-
Singh H, Nugent Z, Demers A, Mahmud S, Bernstein C. Exposure to bisphosphonates and risk of colorectal cancer: A population-based nested case-control study. Cancer. 2011 [Epub ahead of print].
-
(2011)
Cancer
-
-
Singh, H.1
Nugent, Z.2
Demers, A.3
Mahmud, S.4
Bernstein, C.5
-
25
-
-
33746821808
-
Adherence to bisphosphonate therapy and fracture rates in osteoporotic women: Relationship to vertebral and nonvertebral fractures from 2 US claims databases
-
Siris ES, Harris ST, Rosen CJ, Barr CE, Arvesen JN, Abbott TA, et al. Adherence to bisphosphonate therapy and fracture rates in osteoporotic women: relationship to vertebral and nonvertebral fractures from 2 US claims databases. Mayo Clin Proc. 2006; 81: 1013-22.
-
(2006)
Mayo Clin Proc
, vol.81
, pp. 1013-1022
-
-
Siris, E.S.1
Harris, S.T.2
Rosen, C.J.3
Barr, C.E.4
Arvesen, J.N.5
Abbott, T.A.6
-
26
-
-
27844518271
-
Compliance with osteoporosis medications
-
Solomon DH, Avorn J, Katz JN, Finkelstein JS, Arnold M, Polinski JM, et al. Compliance with osteoporosis medications. Arch Intern Med. 2005; 165: 2414-9.
-
(2005)
Arch Intern Med
, vol.165
, pp. 2414-2419
-
-
Solomon, D.H.1
Avorn, J.2
Katz, J.N.3
Finkelstein, J.S.4
Arnold, M.5
Polinski, J.M.6
-
27
-
-
68949203799
-
Adherence to weekly oral bisphosphonate therapy: Cost of wasted drugs and fractures
-
Sheehy O, Kindundu C, Barbeau M, LeLorier J. Adherence to weekly oral bisphosphonate therapy: cost of wasted drugs and fractures. Osteoporos Int. 2009; 20: 1583-94.
-
(2009)
Osteoporos Int
, vol.20
, pp. 1583-1594
-
-
Sheehy, O.1
Kindundu, C.2
Barbeau, M.3
le Lorier, J.4
-
28
-
-
51249087611
-
-
European Medicines Agency, CPMP/EWP/552/95 Rev. 2. Available at, Last accessed 27 October 2010
-
European Medicines Agency 2006. Guideline on the evaluation of medicinal products in the treatment of primary osteoporosis. CPMP/EWP/552/95 Rev. 2. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500003405.pdf. Last accessed 27 October 2010.
-
(2006)
Guideline on the Evaluation of Medicinal Products in the Treatment of Primary Osteoporosis
-
-
-
29
-
-
84857940440
-
-
International Osteoporosis Foundation, About osteoporosis: prevention. Available at, Last accessed 27 October 2010
-
International Osteoporosis Foundation 2009. About osteoporosis: prevention. Available at: http://www.iofbonehealth.org/patientspublic/about-osteoporosis/prevention.html. Last accessed 27 October 2010.
-
(2009)
-
-
-
33
-
-
84857940441
-
-
European Medicines Agency, Assessment report for Fosavance. EMEA/CHMP/188952/2009. Available at, Last accessed 27 October 2010
-
European Medicines Agency 2009 Assessment report for Fosavance. EMEA/CHMP/188952/2009. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Assessment_Report_-_Variation/human/000619/WC500024252.pdf. Last accessed 27 October 2010.
-
(2009)
-
-
-
34
-
-
84857940439
-
-
U.S. Food and Drug Administration, Available at, Last accessed 27 October 2010
-
U.S. Food and Drug Administration 2009. Drug safety newsletter. Volume 2, Number 2. Available at: http://www.fda.gov/downloads/Drugs/DrugSafety/DrugSafetyNewsletter/UCM168579.pdf. Last accessed 27 October 2010.
-
(2009)
Drug Safety Newsletter
, vol.2
, Issue.2
-
-
-
35
-
-
84993812252
-
Zoledronic acid for the treatment and prevention of primary and secondary osteoporosis
-
Rizzoli R. Zoledronic acid for the treatment and prevention of primary and secondary osteoporosis. Ther Adv Musculoskel Dis 2010; 2: 3-16.
-
(2010)
Ther Adv Musculoskel Dis
, vol.2
, pp. 3-16
-
-
Rizzoli, R.1
|