Testosterone and suicidal behavior

Expert Review of Neurotherapeutics

Volumn 12, Issue 3, 2012, Pages 257-259

  Sher, Leo ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

aggression; cognition; depression; mood; suicide; testosterone

Indexed keywords

TESTOSTERONE;

AGGRESSION; BRAIN FUNCTION; COGNITION; MENTAL DISEASE; PATHOPHYSIOLOGY; REVIEW; SUICIDAL BEHAVIOR;

FEMALE; HUMANS; MALE; SUICIDE; TESTOSTERONE;

EID: 84857976567     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/ern.12.6     Document Type: Review

References (20)

1. Shahidi NT. A review of the chemistry, biological action, and clinical applications of anabolic-androgenic steroids. Clin. Ther. 23(9), 1355-1390 (2001). (Pubitemid 32912788)
2. Ebinger M, Sievers C, Ivan D, Schneider HJ, Stalla GK. Is there a neuroendocrinological rationale for testosterone as a therapeutic option in depression? J. Psychopharmacol. 23(7), 841-853 (2009).
3. Zarrouf FA, Artz S, Griffith J, Sirbu C, Kommor M. Testosterone and depression: systematic review and meta-analysis. J. Psychiatr. Pract. 15(4), 289-305 (2009).
4. Tripodianakis J, Markianos M, Rouvali O, Istikoglou C. Gonadal axis hormones in psychiatric male patients after a suicide attempt. Eur. Arch. Psychiatry Clin. Neurosci. 257(3), 135-139 (2007). (Pubitemid 46599125)
5. Markianos M, Tripodianakis J, Istikoglou C et al. Suicide attempt by jumping: a study of gonadal axis hormones in male suicide attempters versus men who fell by accident. Psychiatry Res. 170(1), 82-85 (2009).
6. Perez-Rodriguez MM, Lopez-Castroman J, Martinez-Vigo M et al. Lack of association between testosterone and suicide attempts. Neuropsychobiology 63(2), 125-130 (2011).
7. Butterfield MI, Stechuchak KM, Connor KM et al. Neuroactive steroids and suicidality in posttraumatic stress disorder. Am. J. Psychiatry 162(2), 380-382 (2005). (Pubitemid 40216221)
8. Pope HG Jr, Cohane GH, Kanayama G, Siegel AJ, Hudson JI. Testosterone gel supplementation for men with refractory depression: a randomized, placebo-controlled trial. Am. J. Psychiatry 160(1), 105-111 (2003). (Pubitemid 36042433)
9. Barrett-Connor E, Von Mühlen DG, Kritz- Silverstein D. Bioavailable testosterone and depressed mood in older men: the Rancho Bernardo Study. J. Clin. Endocrinol. Metab. 84(2), 573-577 (1999). (Pubitemid 29075686)
10. Pope HG Jr, Katz DL. Psychiatric and medical effects of anabolic-androgenic steroid use. A controlled study of 160 athletes. Arch. Gen. Psychiatry 51(5), 375-382 (1994). (Pubitemid 24176815)
11. Sher L, Oquendo MA, Mann JJ. Risk of suicide in mood disorders. Clin. Neurosci. Res. 1(5), 337-344 (2001). (Pubitemid 33665040)
12. Chu LW, Tam S, Wong RL, Yik PY et al. Bioavailable testosterone predicts a lower risk of Alzheimer's disease in older men. J. Alzheimers Dis. 21(4), 1335-1345 (2010).
13. Thilers PP, Macdonald SW, Herlitz A. The association between endogenous free testosterone and cognitive performance: a population-based study in 35 to 90 year-old men and women. Psychoneuroendocrinology 31(5), 565-576 (2006).
14. Sher L. Possible link between cognitive dysfunction and suicidal behavior in individuals with alcohol use disorders. Int. J. Disabil. Hum. Dev. 6(2), 149-152 (2007).
15. Gustavsson G, Träskman-Bendz L, Higley JD, Westrin A. CSF testosterone in 43 male suicide attempters. Eur. Neuropsychopharmacol. 13(2), 105-109 (2003). (Pubitemid 36313284)
16. Virkkunen M, Kallio E, Rawlings R et al. Personality profiles and state aggressiveness in Finnish alcoholic, violent offenders, fire setters, and healthy volunteers. Arch. Gen. Psychiatry 51(1), 28-33 (1994). (Pubitemid 24028995)
17. Olweus D, Mattsson A, Schalling D, Löw H. Circulating testosterone levels and aggression in adolescent males: a causal analysis. Psychosom. Med. 50(3), 261-272 (1988).
18. Engström G, Persson B, Levander S. Temperament traits in male suicide attempters and violent offenders. Eur. Psychiatry 14(5), 278-283 (1999). (Pubitemid 36187787)
19. Sher L, Oquendo MA, Galfalvy HC et al. The relationship of aggression to suicidal behavior in depressed patients with a history of alcoholism. Addict. Behav. 30(6), 1144-1153 (2005). (Pubitemid 40745372)
20. Kanayama G, Amiaz R, Seidman S, Pope HG Jr. Testosterone supplementation for depressed men: current research and suggested treatment guidelines. Exp. Clin. Psychopharmacol. 15(6), 529-538 (2007). (Pubitemid 351163127)