메뉴 건너뛰기




Volumn 141, Issue 3, 2012, Pages 651-660

Mast cell inhibition improves pulmonary vascular remodeling in pulmonary hypertension

Author keywords

[No Author keywords available]

Indexed keywords

CHYMASE; CROMOGLYCATE DISODIUM;

EID: 84857976204     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.11-0663     Document Type: Article
Times cited : (58)

References (41)
  • 1
    • 0033987606 scopus 로고    scopus 로고
    • Possibilities and impossibilities in the evaluation of pulmonary vascular disease in congenital heart defects
    • DOI 10.1053/euhj.1999.1698
    • Berger RM. Possibilities and impossibilities in the evaluation of pulmonary vascular disease in congenital heart defects. Eur Heart J. 2000;21(1):17-27. (Pubitemid 30042664)
    • (2000) European Heart Journal , vol.21 , Issue.1 , pp. 17-27
    • Berger, R.M.F.1
  • 2
    • 77954758530 scopus 로고    scopus 로고
    • Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era
    • Humbert M, Sitbon O, Chaouat A, et al. Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era. Circulation. 2010;122(2):156-163.
    • (2010) Circulation , vol.122 , Issue.2 , pp. 156-163
    • Humbert, M.1    Sitbon, O.2    Chaouat, A.3
  • 3
    • 0003756767 scopus 로고
    • Munro Neville A, Walker F, Gottlieb LS, eds. London, England:Chapman and Hall Medical
    • Wagenvoort CA, Mooi WJ. In: Munro Neville A, Walker F, Gottlieb LS, eds. Biopsy Pathology of the Pulmonary Vasculature. London, England:Chapman and Hall Medical; 1989:56-113.
    • (1989) Biopsy Pathology of the Pulmonary Vasculature , pp. 56-113
    • Wagenvoort, C.A.1    Mooi, W.J.2
  • 4
    • 71949129187 scopus 로고    scopus 로고
    • Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure
    • Stenmark KR, Meyrick B, Galie N, Mooi WJ, McMurtry IF. Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure. Am J Physiol Lung Cell Mol Physiol. 2009;297(6):L1013- L1032.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.297 , Issue.6
    • Stenmark, K.R.1    Meyrick, B.2    Galie, N.3    Mooi, W.J.4    McMurtry, I.F.5
  • 5
    • 33947361185 scopus 로고    scopus 로고
    • Pathobiology of pulmonary hypertension
    • DOI 10.1146/annurev.pathol.2.010506.092033, Annual Review of Pathology: Mechanisms of Disease
    • Rabinovitch M. Pathobiology of pulmonary hypertension. Annu Rev Pathol. 2007;2:369-399. (Pubitemid 46448070)
    • (2007) Annual Review of Pathology , vol.2 , pp. 369-399
    • Rabinovitch, M.1
  • 6
    • 67649599147 scopus 로고    scopus 로고
    • Cellular and molecular basis of pulmonary arterial hypertension
    • Morrell NW, Adnot S, Archer SL, et al. Cellular and molecular basis of pulmonary arterial hypertension. J Am Coll Cardiol. 2009;54(suppl 1):S20-S31.
    • (2009) J Am Coll Cardiol , vol.54 , Issue.SUPPL. 1
    • Morrell, N.W.1    Adnot, S.2    Archer, S.L.3
  • 7
    • 54049138069 scopus 로고    scopus 로고
    • Emerging concepts and translational priorities in pulmonary arterial hypertension
    • Michelakis ED, Wilkins MR, Rabinovitch M. Emerging concepts and translational priorities in pulmonary arterial hypertension. Circulation. 2008;118(14):1486-1495.
    • (2008) Circulation , vol.118 , Issue.14 , pp. 1486-1495
    • Michelakis, E.D.1    Wilkins, M.R.2    Rabinovitch, M.3
  • 8
    • 67649579669 scopus 로고    scopus 로고
    • Updated clinical classification of pulmonary hypertension
    • Simonneau G, Robbins IM, Beghetti M, et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2009;54(suppl 1):S43-S54.
    • (2009) J Am Coll Cardiol , vol.54 , Issue.SUPPL. 1
    • Simonneau, G.1    Robbins, I.M.2    Beghetti, M.3
  • 9
    • 77950320624 scopus 로고    scopus 로고
    • Gene expression profile in flow-associated pulmonary arterial hypertension with neointimal lesions
    • van Albada ME, Bartelds B, Wijnberg H, et al. Gene expression profile in flow-associated pulmonary arterial hypertension with neointimal lesions. Am J Physiol Lung Cell Mol Physiol. 2010;298(4):L483-L491.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298 , Issue.4
    • Van Albada, M.E.1    Bartelds, B.2    Wijnberg, H.3
  • 10
    • 34247481344 scopus 로고    scopus 로고
    • Mast cells - key effector cells in immune responses
    • DOI 10.1016/j.it.2007.03.003, PII S1471490607000713
    • Metz M, Maurer M. Mast cells-key effector cells in immune responses. Trends Immunol. 2007;28(5):234-241. (Pubitemid 46654869)
    • (2007) Trends in Immunology , vol.28 , Issue.5 , pp. 234-241
    • Metz, M.1    Maurer, M.2
  • 11
    • 67649844313 scopus 로고    scopus 로고
    • Inflammation, growth factors, and pulmonary vascular remodeling
    • Hassoun PM, Mouthon L, Barberà JA, et al. Inflammation, growth factors, and pulmonary vascular remodeling. J Am Coll Cardiol. 2009;54(suppl 1):S10-S19.
    • (2009) J Am Coll Cardiol , vol.54 , Issue.SUPPL. 1
    • Hassoun, P.M.1    Mouthon, L.2    Barberà, J.A.3
  • 12
    • 0032877551 scopus 로고    scopus 로고
    • Increased expression of mast cell chymase in the lungs of patients with congenital heart disease associated with early pulmonary vascular disease
    • Hamada H, Terai M, Kimura H, Hirano K, Oana S, Niimi H. Increased expression of mast cell chymase in the lungs of patients with congenital heart disease associated with early pulmonary vascular disease. Am J Respir Crit Care Med. 1999;160(4):1303-1308. (Pubitemid 29487474)
    • (1999) American Journal of Respiratory and Critical Care Medicine , vol.160 , Issue.4 , pp. 1303-1308
    • Hamada, H.1    Terai, M.2    Kimura, H.3    Hirano, K.4    Oana, S.5    Niimi, H.6
  • 13
    • 3142722666 scopus 로고    scopus 로고
    • Longitudinal transcriptional analysis of developing neointimal vascular occlusion and pulmonary hypertension in rats
    • DOI 10.1152/physiolgenomics.00198.2003
    • Vaszar LT, Nishimura T, Storey JD, et al. Longitudinal transcriptional analysis of developing neointimal vascular occlusion and pulmonary hypertension in rats. Physiol Genomics. 2004;17(2):150-156. (Pubitemid 38924161)
    • (2004) Physiological Genomics , vol.17 , pp. 150-156
    • Vaszar, L.T.1    Nishimura, T.2    Storey, J.D.3    Zhao, G.4    Qiu, D.5    Faul, J.L.6    Pearl, R.G.7    Kao, P.N.8
  • 15
    • 33748041146 scopus 로고    scopus 로고
    • Role of chymase-dependent angiotensin II formation in monocrotaline-induced pulmonary hypertensive rats
    • DOI 10.1203/01.pdr.0000219431.45075.d9, PII 0000645020060700000015
    • Kishi K, Jin D, Takai S, et al. Role of chymase-dependent angiotensin II formation in monocrotaline-induced pulmonary hypertensive rats. Pediatr Res. 2006;60(1):77-82. (Pubitemid 44297617)
    • (2006) Pediatric Research , vol.60 , Issue.1 , pp. 77-82
    • Kishi, K.1    Jin, D.2    Takai, S.3    Muramatsu, M.4    Katayama, H.5    Tamai, H.6    Miyazaki, M.7
  • 16
    • 46249128098 scopus 로고    scopus 로고
    • Prevention of mast cell degranulation by disodium cromoglycate attenuates the development of hypoxic pulmonary hypertension in rats exposed to chronic hypoxia
    • DOI 10.1159/000121410
    • Banasová A, Maxová H, Hampl V, et al. Prevention of mast cell degranulation by disodium cromoglycate attenuates the development of hypoxic pulmonary hypertension in rats exposed to chronic hypoxia. Respiration. 2008;76(1): 102-107. (Pubitemid 351914146)
    • (2008) Respiration , vol.76 , Issue.1 , pp. 102-107
    • Banasova, A.1    Maxova, H.2    Hampl, V.3    Vizek, M.4    Povysilova, V.5    Novotna, J.6    Vajnerova, O.7    Hnilickova, O.8    Herget, J.9
  • 17
    • 5044221645 scopus 로고    scopus 로고
    • Mast cells in vulnerable coronary plaques: Potential mechanisms linking mast cell activation to plaque erosion and rupture
    • DOI 10.1097/00041433-200410000-00011
    • Lindstedt KA, Kovanen PT. Mast cells in vulnerable coronary plaques: potential mechanisms linking mast cell activation to plaque erosion and rupture. Curr Opin Lipidol. 2004; 15(5):567-573. (Pubitemid 39336585)
    • (2004) Current Opinion in Lipidology , vol.15 , Issue.5 , pp. 567-573
    • Lindstedt, K.A.1    Kovanen, P.T.2
  • 18
    • 33947326318 scopus 로고    scopus 로고
    • Persistent Pulmonary Hypertension of the Newborn With Transposition of the Great Arteries
    • DOI 10.1016/j.athoracsur.2006.11.001, PII S0003497506021382
    • Roofthooft MT, Bergman KA, Waterbolk TW, Ebels T, Bartelds B, Berger RM. Persistent pulmonary hypertension of the newborn with transposition of the great arteries. Ann Thorac Surg. 2007;83(4):1446-1450. (Pubitemid 46440761)
    • (2007) Annals of Thoracic Surgery , vol.83 , Issue.4 , pp. 1446-1450
    • Roofthooft, M.T.R.1    Bergman, K.A.2    Waterbolk, T.W.3    Ebels, T.4    Bartelds, B.5    Berger, R.M.F.6
  • 20
    • 33751194658 scopus 로고    scopus 로고
    • Treprostinil in advanced experimental pulmonary hypertension: Beneficial outcome without reversed pulmonary vascular remodeling
    • van Albada ME, van Veghel R, Cromme-Dijkhuis AH, Schoemaker RG, Berger RM. Treprostinil in advanced experimental pulmonary hypertension: beneficial outcome without reversed pulmonary vascular remodeling. J Cardiovasc Pharmacol. 2006;48(5):249-254.
    • (2006) J Cardiovasc Pharmacol , vol.48 , Issue.5 , pp. 249-254
    • Van Albada, M.E.1    Van Veghel, R.2    Cromme-Dijkhuis, A.H.3    Schoemaker, R.G.4    Berger, R.M.5
  • 21
    • 33645219380 scopus 로고    scopus 로고
    • Chymase inhibition prevents cardiac fibrosis and dysfunction after myocardial infarction in rats
    • Kanemitsu H, Takai S, Tsuneyoshi H, et al. Chymase inhibition prevents cardiac fibrosis and dysfunction after myocardial infarction in rats. Hypertens Res. 2006;29(1) : 57-64.
    • (2006) Hypertens Res , vol.29 , Issue.1 , pp. 57-64
    • Kanemitsu, H.1    Takai, S.2    Tsuneyoshi, H.3
  • 22
    • 79957999313 scopus 로고    scopus 로고
    • Mast cells promote lung vascular remodeling in pulmonary hypertension
    • Hoffmann J, Yin J, Kukucka M, et al. Mast cells promote lung vascular remodeling in pulmonary hypertension. Eur Respir J. 2011;37(6):1400-1410.
    • (2011) Eur Respir J , vol.37 , Issue.6 , pp. 1400-1410
    • Hoffmann, J.1    Yin, J.2    Kukucka, M.3
  • 23
    • 78649745131 scopus 로고    scopus 로고
    • Reversible or irreversible remodeling in pulmonary arterial hypertension
    • Sakao S, Tatsumi K, Voelkel NF. Reversible or irreversible remodeling in pulmonary arterial hypertension. Am J Respir Cell Mol Biol. 2010;43(6):629-634.
    • (2010) Am J Respir Cell Mol Biol , vol.43 , Issue.6 , pp. 629-634
    • Sakao, S.1    Tatsumi, K.2    Voelkel, N.F.3
  • 24
    • 33746206340 scopus 로고    scopus 로고
    • Bosentan therapy in patients with Eisenmenger syndrome: A multicenter, double-blind, randomized, placebo-controlled study
    • Bosentan Randomized Trial of Endothelin Antagonist Therapy-5 (BREATHE-5) Investigators
    • Galiè N, Beghetti M, Gatzoulis MA, et al;Bosentan Randomized Trial of Endothelin Antagonist Therapy-5 (BREATHE-5) Investigators. Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation. 2006; 114(1):48-54.
    • (2006) Circulation , vol.114 , Issue.1 , pp. 48-54
    • Galiè, N.1    Beghetti, M.2    Gatzoulis, M.A.3
  • 26
    • 77956709644 scopus 로고    scopus 로고
    • Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy
    • Ghofrani HA, Morrell NW, Hoeper MM, et al. Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy. Am J Respir Crit Care Med. 2010;182(9):1171-1177.
    • (2010) Am J Respir Crit Care Med , vol.182 , Issue.9 , pp. 1171-1177
    • Ghofrani, H.A.1    Morrell, N.W.2    Hoeper, M.M.3
  • 27
    • 77957694135 scopus 로고    scopus 로고
    • Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats
    • Bogaard HJ, Natarajan R, Mizuno S, et al. Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats. Am J Respir Crit Care Med. 2010;182(5):652-660.
    • (2010) Am J Respir Crit Care Med , vol.182 , Issue.5 , pp. 652-660
    • Bogaard, H.J.1    Natarajan, R.2    Mizuno, S.3
  • 28
    • 77952019637 scopus 로고    scopus 로고
    • Combination therapy with bosentan and sildenafil in Eisenmenger syndrome: A randomized, placebo-controlled, double-blinded trial
    • Iversen K, Jensen AS, Jensen TV, Vejlstrup NG, Søndergaard L. Combination therapy with bosentan and sildenafil in Eisenmenger syndrome: a randomized, placebo-controlled, double-blinded trial. Eur Heart J. 2010;31(9):1124-1131.
    • (2010) Eur Heart J , vol.31 , Issue.9 , pp. 1124-1131
    • Iversen, K.1    Jensen, A.S.2    Jensen, T.V.3    Vejlstrup, N.G.4    Søndergaard, L.5
  • 29
    • 77249175436 scopus 로고    scopus 로고
    • Mast cell peptidases: Chameleons of innate immunity and host defense
    • Trivedi NN, Caughey GH. Mast cell peptidases: chameleons of innate immunity and host defense. Am J Respir Cell Mol Biol. 2010;42(3):257-267.
    • (2010) Am J Respir Cell Mol Biol , vol.42 , Issue.3 , pp. 257-267
    • Trivedi, N.N.1    Caughey, G.H.2
  • 30
    • 34948852371 scopus 로고    scopus 로고
    • Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors
    • DOI 10.1038/nm1649, PII NM1649
    • Soucek L, Lawlor ER, Soto D, Shchors K, Swigart LB, Evan GI. Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors. Nat Med. 2007;13(10):1211-1218. (Pubitemid 47530639)
    • (2007) Nature Medicine , vol.13 , Issue.10 , pp. 1211-1218
    • Soucek, L.1    Lawlor, E.R.2    Soto, D.3    Shchors, K.4    Swigart, L.B.5    Evan, G.I.6
  • 33
    • 76749104410 scopus 로고    scopus 로고
    • Dual inhibition of cathepsin G and chymase is effective in animal models of pulmonary inflammation
    • Maryanoff BE, de Garavilla L, Greco MN, et al. Dual inhibition of cathepsin G and chymase is effective in animal models of pulmonary inflammation. Am J Respir Crit Care Med. 2010;181(3):247-253.
    • (2010) Am J Respir Crit Care Med , vol.181 , Issue.3 , pp. 247-253
    • Maryanoff, B.E.1    De Garavilla, L.2    Greco, M.N.3
  • 34
    • 68349160704 scopus 로고    scopus 로고
    • Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
    • Liu J, Divoux A, Sun J, et al. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med. 2009;15(8):940-945.
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 940-945
    • Liu, J.1    Divoux, A.2    Sun, J.3
  • 35
    • 77956199020 scopus 로고    scopus 로고
    • Mast cell stabilization improves survival by preventing apoptosis in sepsis
    • Ramos L, Peña G, Cai B, Deitch EA, Ulloa L. Mast cell stabilization improves survival by preventing apoptosis in sepsis. J Immunol. 2010;185(1):709-716.
    • (2010) J Immunol , vol.185 , Issue.1 , pp. 709-716
    • Ramos, L.1    Peña, G.2    Cai, B.3    Deitch, E.A.4    Ulloa, L.5
  • 36
    • 51849130662 scopus 로고    scopus 로고
    • Severe pulmonary arterial hypertension: A forme fruste of cancer?
    • Humbert M, Hoeper MM. Severe pulmonary arterial hypertension: a forme fruste of cancer? Am J Respir Crit Care Med. 2008;178(6):551-552.
    • (2008) Am J Respir Crit Care Med , vol.178 , Issue.6 , pp. 551-552
    • Humbert, M.1    Hoeper, M.M.2
  • 37
    • 77953026428 scopus 로고    scopus 로고
    • Evidence for the use of combination targeted therapeutic approaches for the management of pulmonary arterial hypertension
    • O'Callaghan DS, Savale L, Jais X, et al. Evidence for the use of combination targeted therapeutic approaches for the management of pulmonary arterial hypertension. Respir Med. 2010;104(suppl 1):S74-80.
    • (2010) Respir Med , vol.104 , Issue.SUPPL. 1
    • O'Callaghan, D.S.1    Savale, L.2    Jais, X.3
  • 39
    • 68849084078 scopus 로고    scopus 로고
    • Chymase inhibition provides pancreatic islet protection in hamsters with streptozotocin-induced diabetes
    • Takai S, Jin D, Ohzu M, Tanaka K, Miyazaki M. Chymase inhibition provides pancreatic islet protection in hamsters with streptozotocin-induced diabetes. J Pharmacol Sci. 2009; 110(4):459-465.
    • (2009) J Pharmacol Sci , vol.110 , Issue.4 , pp. 459-465
    • Takai, S.1    Jin, D.2    Ohzu, M.3    Tanaka, K.4    Miyazaki, M.5
  • 40
    • 77954373221 scopus 로고    scopus 로고
    • Chymase inhibitor prevents the nonalcoholic steatohepatitis in hamsters fed a methionine-and choline-deficient diet
    • Tashiro K, Takai S, Jin D, et al. Chymase inhibitor prevents the nonalcoholic steatohepatitis in hamsters fed a methionine-and choline-deficient diet. Hepatol Res. 2010;40(5) : 514-523.
    • (2010) Hepatol Res , vol.40 , Issue.5 , pp. 514-523
    • Tashiro, K.1    Takai, S.2    Jin, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.