Automated image analysis of hand radiographs reveals widened joint spaces in patients with long-term control of acromegaly: Relation to disease activity and symptoms

European Journal of Endocrinology

Volumn 166, Issue 3, 2012, Pages 407-413

  Biermasz, N R ^a   Van 't Klooster, R ^a   Wassenaar, M J E ^a   Malm, S H ^a   Claessen, K M J A ^a   Nelissen, R G H H ^a   Roelfsema, F ^a   Pereira, A M ^a   Kroon, H M ^a   Stoel, B C ^a   Romijn, J A ^a   Kloppenburg, M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN C;

ACROMEGALY; ADULT; ARTHRALGIA; ARTICLE; AUTOMATION; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DATA ANALYSIS SOFTWARE; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE CONTROL; FEMALE; HAND RADIOGRAPHY; HUMAN; IMAGE ANALYSIS; JOINT CAVITY; MAJOR CLINICAL STUDY; MALE; METACARPOPHALANGEAL JOINT; PRIORITY JOURNAL; PROXIMAL INTERPHALANGEAL JOINT; SEX DIFFERENCE;

ACROMEGALY; ADULT; AGED; CROSS-SECTIONAL STUDIES; FEMALE; FOLLOW-UP STUDIES; HAND; HAND JOINTS; HUMANS; MALE; MIDDLE AGED; PAIN MEASUREMENT; PROSPECTIVE STUDIES; TIME FACTORS;

EID: 84857941092     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-11-0795     Document Type: Article

References (20)

1. Melmed S. Medical progress: acromegaly. New England Journal of Medicine 2006 355 2558-2573. (doi:10.1056/NEJMra062453)
2. Layton MW, Fudman EJ, Barkan A, Braunstein EM & Fox IH. Acromegalic arthropathy. Characteristics and response to therapy. Arthritis and Rheumatism 1988 31 1022-1027. (doi:10.1002/art. 1780310813)
3. Biermasz NR, Pereira AM, Smit JW, Romijn JA & Roelfsema F. Morbidity after long-term remission for acromegaly: persisting joint-related complaints cause reduced quality of life. Journal of Clinical Endocrinology and Metabolism 2005 90 2731-2739. (doi:10.1210/jc.2004-2297)
4. Wassenaar MJ, Biermasz NR, van Duinen N, van der Klaauw AA, Pereira AM, Roelfsema F, Smit JW, Kroon HM, Kloppenburg M & Romijn JA. High prevalence of arthropathy, according to the definitions of radiological and clinical osteoarthritis, in patients with long-term cure of acromegaly: a case-control study. European Journal of Endocrinology 2009 160 357-365. (doi:10.1530/EJE- 08-0845)
5. van 't Klooster R, Hendriks EA, Watt I, Kloppenburg M, Reiber JH & Stoel BC. Automatic quantification of osteoarthritis in hand radiographs: validation of a new method to measure joint space width. Osteoarthritis and Cartilage 2008 16 18-25. (doi:10.1016/j. joca.2007.05.015)
6. Biermasz NR, Dekker FW, Pereira AM, van Thiel SW, Schutte PJ, van Dulken H, Romijn JA & Roelfsema F. Determinants of survival in treated acromegaly in a single center: predictive value of serial insulin-like growth factor I measurements. Journal of Clinical Endocrinology and Metabolism 2004 89 2789-2796. (doi:10. 1210/jc.2003-032041)
7. van Aken J, van Bilsen JH, Allaart CF, Huizinga TW & Breedveld FC. The Leiden Early Arthritis Clinic. Clinical and Experimental Rheumatology 2003 21 S100-S105. (Pubitemid 37265597)
8. Huetink K, Nelissen RGHH, Watt I, van Erkel AR & Bloem JL. Localized development of knee osteoarthritis can be predicted from MR imaging findings a decade earlier. Radiology 2010 256 536-546. (doi:10.1148/radiol.10090683)
9. Altman R, Alarcon G, Appelrouth D, Bloch D, Borenstein D, Brandt K, Brown C, Cooke TD, Daniel W & Gray R. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand. Arthritis and Rheumatism 1990 33 1601-1610. (doi:10.1002/art.1780331101)
10. Kellgren JH & Lawrence JS. Radiological assessment of osteoarthrosis. Annals of the Rheumatic Diseases 1957 16 494-502. (doi:10.1136/ard.16.4.494)
11. Kellgren JH & Lawrence JS. Osteo-arthrosis and disk degeneration in an urban population. Annals of the Rheumatic Diseases 1958 17 388-397. (doi:10.1136/ard.17.4.388)
12. Janssen YJ, Frolich M & Roelfsema F. A low starting dose of genotropin in growth hormone-deficient adults. Journal of Clinical Endocrinology and Metabolism 1997 82 129-135. (doi:10.1210/ jc.82.1.129)
13. Cole TJ. The LMS method for constructing normalized growth standards. European Journal of Clinical Nutrition 1990 44 45-60. (Pubitemid 20177198)
14. Rikken B, van Doorn J, Ringeling A, Van den Brande JL, Massa G & Wit JM. Plasma levels of insulin-like growth factor (IGF)-1, IGF1 and IGF-binding protein-3 in the evaluation of childhood growth hormone deficiency. Hormone Research 1998 50 166-176. (doi:10.1159/000023268)
15. Wassenaar MJ, Biermasz NR, Bijsterbosch J, Pereira AM, Meulenbelt I, Smit JW, Roelfsema F, Kroon HM, Romijn JA & Kloppenburg M. Arthropathy in long-term cured acromegaly is characterised by osteophytes without joint space narrowing: a comparison with generalised osteoarthritis. Annals of the Rheumatic Diseases 2011 70 320-325. (doi:10.1136/ard.2010. 131698)
16. Giustina A, Mazziotti G & Canalis E. Growth hormone, insulin-like growth factors, and the skeleton. Endocrine Reviews 2008 29 535-559. (doi:10.1210/er.2007-0036)
17. Colao A, Marzullo P, Vallone G, Giaccio A, Ferone D, Rossi E, Scarpa R, Smaltino F & Lombardi G. Ultrasonographic evidence of joint thickening reversibility in acromegalic patients treated with lanreotide for 12 months. Clinical Endocrinology 1999 51 611-618. (doi:10.1046/j.1365-2265.1999.00851.x)
18. Colao A, Marzullo P, Vallone G, Marino V, Annecchino M, Ferone D, De Brasi D, Scarpa R, Oriente P & Lombardi G. Reversibility of joint thickening in acromegalic patients: an ultrasonography study. Journal of Clinical Endocrinology and Metabolism 1998 83 2121-2125. (doi:10.1210/jc.83.6.2121)
19. Altman RD, Hochberg M, Murphy WA Jr, Wolfe F & Lequesne M. Atlas of individual radiographic features in osteoarthritis. Osteoarthritis and Cartilage 1995 3 (Supplement A) 3-70.
20. Kwok WY, Bijsterbosch J, Malm SH, Biermasz NR, Huetink K, Nelissen RG, Meulenbelt I, Huizinga TW, van 't Klooster R, Stoel BC & Kloppenburg M. Validity of joint space measurements in hand osteoarthritis. Osteoarthritis and Cartilage 2011 19 1349-1355. (doi:10.1016/j.joca.2011.08.011)