Low glycemic index treatment for epilepsy in tuberous sclerosis complex

Epilepsy Research

Volumn 99, Issue 1-2, 2012, Pages 180-182

  Larson, Anna M ^a   Pfeifer, Heidi H ^a   Thiele, Elizabeth A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Epilepsy; Ketogenic diet; Low glycemic index treatment; MTOR pathway; Tuberous sclerosis complex

Indexed keywords

ANTICONVULSIVE AGENT;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DIET THERAPY; DISEASE CONTROL; EPILEPSY; FEMALE; GENERAL HOSPITAL; GLYCEMIC INDEX; HUMAN; INTENTION TO TREAT ANALYSIS; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; TREATMENT DURATION; TUBEROUS SCLEROSIS; UNITED STATES;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; EPILEPSY; FEMALE; GLYCEMIC INDEX; HUMANS; INFANT; KETOGENIC DIET; MALE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; TUBEROUS SCLEROSIS; YOUNG ADULT;

EID: 84857920108     PISSN: 09201211     EISSN: 18726844     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2011.10.021     Document Type: Article

References (9)

1. Crino P., Nathanson K., Henske E. The tuberous sclerosis complex. N. Engl. J. Med. 2006, 355:1345-1356.
2. Chu-Shore C., Major P., Camposano S., Muzykewicz D., Thiele E. The natural history of epilepsy in tuberous sclerosis complex. Epilepsia 2010, 51:1236-1241.
3. Pfeifer H., Thiele E. Low-glycemic-index treatment: a liberalized ketogenic diet for treatment of intractable epilepsy. Neurology 2005, 65:1810-1812.
4. Muzykewicz D.A., Lyczkowski D.A., Memon N., Conant K.D., Pfeifer H.H., Thiele E.A. Efficacy, safety, and tolerability of the low glycemic index treatment in pediatric epilepsy. Epilepsia 2009, 50:1118-1126.
5. Kossoff E., Thiele E., Pfeifer H., McGrogan J., Freeman J. Tuberous sclerosis complex and the ketogenic diet. Epilepsia 2005, 46:1684-1686.
6. Pfeifer H., Lyczkowski D., Thiele E. Low glycemic index treatment: implementation and new insights into efficacy. Epilepsia 2008, 49:42-45.
7. Erbayat-Altay E., Zeng L., Xu L., Gutmann D.H., Wong M. The natural history and treatment of epilepsy in a murine model of tuberous sclerosis. Epilepsia 2007, 48:1470-1476.
8. Sengupta S., Peterson T., Sabatini D. Regulation of the mTOR complex 1 Pathway by nutrients, growth factors, and stress. Mol. Cell 2010, 40:310-322.
9. Wong M. Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: from tuberous sclerosis to common acquired epilepsies. Epilepsia 2010, 51:27-36.