Changes in global function and regional ventilation and perfusion on SPECT during the course of radiotherapy in patients with non-small-cell lung cancer

International Journal of Radiation Oncology Biology Physics

Volumn 82, Issue 4, 2012, Pages

  Yuan, Shuanghu ^a,c   Frey, Kirk A ^b   Gross, Milton D ^b   Hayman, James A ^a   Arenberg, Doug ^b   Cai, Xu Wei ^a   Ramnath, Nithya ^b   Hassan, Khaled ^b   Moran, Jean ^a   Eisbruch, Avraham ^a   Ten Haken, Randall K ^a   Kong, Feng Ming ^a,d  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c Department of Radiation Oncology   (China)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Non small cell lung cancer; Perfusion; Radiotherapy; Single photon emission computerized tomography; Ventilation

Indexed keywords

ADVERSE EVENTS; COMMON TERMINOLOGY CRITERIA; FUNCTIONAL ACTIVITIES; GLOBAL FUNCTIONS; IPSILATERAL LUNGS; LUNG TISSUE; LUNG TUMOR; NON SMALL CELL LUNG CANCER; PERFUSION; PULMONARY FUNCTION TEST; Q-FUNCTIONS; REGIONAL LUNG FUNCTIONS; REGIONAL VENTILATION; SEMI-QUANTITATIVE; SINGLE PHOTON EMISSION; SPECT IMAGES; TUMOR VOLUMES; V-DEFECTS;

BIOLOGICAL ORGANS; CHEMOTHERAPY; DRUG PRODUCTS; PARTICLE BEAMS; PATIENT MONITORING; RADIOTHERAPY; TUMORS; VENTILATION;

SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY;

ADULT; AGED; ARTICLE; BREATHING; CANCER RADIOTHERAPY; DYSPNEA; FEMALE; HUMAN; LUNG FUNCTION TEST; LUNG NON SMALL CELL CANCER; LUNG VENTILATION PERFUSION RATIO; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RADIATION DOSE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; DYSPNEA; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; LUNG; LUNG NEOPLASMS; MALE; MIDDLE AGED; ORGAN SPARING TREATMENTS; PROSPECTIVE STUDIES; PULMONARY DIFFUSING CAPACITY; RADIOTHERAPY DOSAGE; RESPIRATION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; VITAL CAPACITY;

EID: 84857910771     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.07.044     Document Type: Article

References (19)

1. D.M. Parkin, F. Bray, and J. Ferlay Global cancer statistics, 2002 CA Cancer J Clin 55 2005 74 108
2. S. Tyldesley, C. Boyd, and K. Schulze Estimating the need for radiotherapy for lung cancer: An evidence-based, epidemiologic approach Int J Radiat Oncol Biol Phys 49 2001 973 985
3. G.R. Borst, K. De Jaeger, and J.S. Belderbos Pulmonary function changes after radiotherapy in non-small-cell lung cancer patients with long-term disease-free survival Int J Radiat Oncol Biol Phys 62 2005 639 644
4. L.J. Boersma, E.M. Damen, and R.W. de Boer Dose-effect relations for local functional and structural changes of the lung after irradiation for malignant lymphoma Radiother Oncol 32 1994 201 209
5. I.W. Gayed, J. Chang, and E.E. Kim Lung perfusion imaging can risk stratify lung cancer patients for the development of pulmonary complications after chemoradiation J Thorac Oncol 3 2008 858 864
6. Y. Shioyama, S.Y. Jang, and H.H. Liu Preserving functional lung using perfusion imaging and intensity-modulated radiation therapy for advanced-stage non-small cell lung cancer Int J Radiat Oncol Biol Phys 68 2007 1349 1358
7. K. Lavrenkov, J.A. Christian, and M. Partridge A potential to reduce pulmonary toxicity: The use of perfusion SPECT with IMRT for functional lung avoidance in radiotherapy of non-small cell lung cancer Radiother Oncol 83 2007 156 162
8. Y. Seppenwoolde, M. Engelsman, and K. De Jaeger Optimizing radiation treatment plans for lung cancer using lung perfusion information Radiother Oncol 63 2002 165 177
9. S.M. McGuire, S. Zhou, and L.B. Marks A methodology for using SPECT to reduce intensity-modulated radiation therapy (IMRT) dose to functioning lung Int J Radiat Oncol Biol Phys 66 2006 1543 1552
10. J.A. Christian, M. Partridge, and E. Nioutsikou The incorporation of SPECT functional lung imaging into inverse radiotherapy planning for non-small cell lung cancer Radiother Oncol 77 2005 271 277
11. K. Lavrenkov, S. Singh, and J.A. Christian Effective avoidance of a functional spect-perfused lung using intensity modulated radiotherapy (IMRT) for non-small cell lung cancer (NSCLC): An update of a planning study Radiother Oncol 91 2009 349 352
12. S.K. Das, M.M. Miften, and S. Zhou Feasibility of optimizing the dose distribution in lung tumors using fluorine-18-fluorodeoxyglucose positron emission tomography and single photon emission computed tomography guided dose prescriptions Med Phys 31 2004 1452 1461
13. T. Yamamoto, S. Kabus, and J. von Berg Impact of four-dimensional computed tomography pulmonary ventilation imaging-based functional avoidance for lung cancer radiotherapy Int J Radiat Oncol Biol Phys 79 2011 279 288
14. Y. Seppenwoolde, S.H. Muller, and J.C. Theuws Radiation dose-effect relations and local recovery in perfusion for patients with non-small-cell lung cancer Int J Radiat Oncol Biol Phys 47 2000 681 690
15. F.M. Kong, K.A. Frey, and L.E. Quint A pilot study of [18F]fluorodeoxyglucose positron emission tomography scans during and after radiation-based therapy in patients with non small-cell lung cancer J Clin Oncol 25 2007 3116 3123
16. S. Yuan, F.A. Kirk, and M.D. Gross Semi-quantification and classification of local pulmonary function by V/Q SPECT in patients with non-small cell lung cancer J Thorac Oncol 6 2011 71 78
17. J. Zhang, J. Ma, and S. Zhou Radiation-induced reductions in regional lung perfusion: 0.1-12 year data from a prospective clinical study Int J Radiat Oncol Biol Phys 76 2010 425 432
18. M. Feng, F.M. Kong, and M. Gross Using fluorodeoxyglucose positron emission tomography to assess tumor volume during radiotherapy for non-small-cell lung cancer and its potential impact on adaptive dose escalation and normal tissue sparing Int J Radiat Oncol Biol Phys 73 2009 1228 1234
19. Kong FM, Mahasittiwat P, Yuan S, et al. Define tumor volume during radiaotherapy to individualize adaptive radiation dose escalation in n non-small cell lung cancer. Imaging for treatment assessment in radiation therapy (ITART) 2010. Abstract 14327.